Abstract 17380: Can Understanding of National Search Engine Queries Inform Heart Failure Prevention? National Internet Search Engine Queries Correlates With CHF Prevalence but Not Outcomes

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
adebayo atanda ◽  
Olajide Buhari ◽  
Mohammed Alarfaj ◽  
Hassan Khalil ◽  
Alberto Batresh ◽  
...  

Introduction: Congestive heart failure (CHF) remains an epidemic with rising prevalence and a contributing cause of 1 in 9 deaths in the United States. An understanding of internet search engines for congestive heart failure as informational and initial diagnostic tools may enable targeted education strategies. Hypothesis: There is a correlation between CHF google search and outcomes. Methods: We used google trends, a publicly available google tool, to identify search frequency for CHF and related terms like early signs of heart failure, congestive heart failure facts over a 2 year period from 2014-2016 across regions of the United States. We then evaluated the prevalence of hospitalization and mortality rates among Medicare beneficiaries based on Center for Disease Control (CDC) data. Utilizing Pearson correlation (R) test, we determined the association between relative search frequency (RSF) in various states versus CHF hospitalization and mortality rates. Results: Across the 50 states in United States, there were 25 searches related to the search terms. There was a moderate positive correlation (R 0.4-0.7) between CHF hospitalization (R= 0.43) and mortality (R=0.51) with relative search frequency in google trends. Conclusions: We demonstrated a correlation between internet search and CHF prevalence and hospitalization. The emergence of data analytics in CHF care may enable greater understanding of patient questions in CHF to better target education and prevention.

2018 ◽  
Vol 33 (4) ◽  
pp. 611-615 ◽  
Author(s):  
Zachary H. Hopkins ◽  
Aaron M. Secrest

Purpose: Google Trends (GT) offers insights into public interests and behaviors and holds potential for guiding public health campaigns. We evaluated trends in US searches for sunscreen, sunburn, skin cancer, and melanoma and their relationships with melanoma outcomes. Design: Google Trends was queried for US search volumes from 2004 to 2017. Time-matched search term data were correlated with melanoma outcomes data from Surveillance Epidemiology and End Results Program and United States Cancer Statistics databases (2004-2014 and 2010-2014, respectively). Setting: Users of the Google search engine in the United States. Participants: Google search engine users in the United States. This represents approximately 65% of the population. Measures: Search volumes, melanoma outcomes. Analysis: Pearson correlations between search term volumes, time, and national melanoma outcomes. Spearman correlations between state-level search data and melanoma outcomes. Results: The terms “sunscreen,” “sunburn,” “skin cancer,” and “melanoma” were all highly correlated ( P < .001), with sunscreen and sunburn having the greatest correlation ( r = 0.95). Sunscreen/sunburn searches have increased over time, but skin cancer/melanoma searches have decreased ( P < .05). Nationally, sunscreen, sunburn, and skin cancer were significantly correlated with melanoma incidence. At the state level, only sunscreen and melanoma searches were significantly correlated with melanoma incidence. Conclusions: We conclude that online skin cancer prevention campaigns should focus on the search terms “sunburn” and “sunscreen,” given the decreasing online searches for skin cancer and melanoma. This is reinforced by the finding that sunscreen searches are higher in areas with higher melanoma incidence.


2019 ◽  
Vol 16 ◽  
pp. 101007
Author(s):  
Kristin Primm ◽  
Alva O. Ferdinand ◽  
Timothy Callaghan ◽  
Marvellous A. Akinlotan ◽  
Samuel D. Towne ◽  
...  

Author(s):  
Belén Mora Garijo ◽  
Jonathan E. Katz ◽  
Aubrey Greer ◽  
Mia Gonzalgo ◽  
Alejandro García López ◽  
...  

AbstractSeveral diseases associated with erectile dysfunction (ED), such as type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD), are known to have seasonal variation, with increased incidence during winter months. However, no literature exists on whether this chronological-seasonal evolution is also present within ED symptomatology. We hypothesized ED would follow the seasonal pattern of its lifestyle-influenced comorbid conditions and exhibit increased incidence during winter months. In order to investigate the seasonal variation of ED in the United States between 2009 and 2019, Internet search query data were obtained using Google Trends. Normalized search volume was determined during the winter and summer seasons for ED, other diseases known to be significantly associated with ED (T2DM and CAD), kidney stones (positive control), and prostate cancer (negative control). There were significantly more internet search queries for ED during the winter than during the summer (p = 0.001). CAD and T2DM also had significantly increased search volume during winter months compared to summer months (p < 0.001 and p = 0.011, respectively). By contrast, searches for kidney stones were significantly increased in the summer than in the winter (p < 0.001). There was no significant seasonal variation in the relative search frequency for prostate cancer (p = 0.75). In conclusion, Google Trends internet search data across a ten-year period in the United States suggested a seasonal variation in ED, which implies an increase in ED during winter. This novel finding in ED epidemiology may help increase awareness of ED’s associated lifestyle risk factors, which may facilitate early medical evaluation and treatment for those at risk of both ED and cardiovascular disease.


PEDIATRICS ◽  
1980 ◽  
Vol 66 (6) ◽  
pp. 972-976
Author(s):  
H. Peter Chase ◽  
Vijay Kumar ◽  
Richard T. Caldwell ◽  
Donough O'Brien

Kwashiorkor, with typical edema and skin rash is occasionally seen in affluent countries as a result of severe protein restriction. Treatment is with a lactose-free formula after rehydration and sometimes after a period of parenteral alimentation. Complications of therapy included: diarrhea, congestive heart failure, infections, a bleeding tendency, and seizures. Two of the 14 children in this series died.


Neurosurgery ◽  
2012 ◽  
Vol 71 (4) ◽  
pp. 795-803 ◽  
Author(s):  
Fred Rincon ◽  
Sayantani Ghosh ◽  
Saugat Dey ◽  
Mitchell Maltenfort ◽  
Matthew Vibbert ◽  
...  

AbstractBACKGROUND:Traumatic brain injury (TBI) is a major cause of disability, morbidity, and mortality. The effect of the acute respiratory distress syndrome and acute lung injury (ARDS/ALI) on in-hospital mortality after TBI remains controversial.OBJECTIVE:To determine the epidemiology of ARDS/ALI, the prevalence of risk factors, and impact on in-hospital mortality after TBI in the United States.METHODS:Retrospective cohort study of admissions of adult patients &gt;18 years with a diagnosis of TBI and ARDS/ALI from 1988 to 2008 identified through the Nationwide Inpatient Sample.RESULTS:During the 20-year study period, the prevalence of ARDS/ALI increased from 2% (95% confidence interval [CI], 2.1%–2.4%) in 1988 to 22% (95% CI, 21%–22%) in 2008 (P &lt; .001). ARDS/ALI was more common in younger age; males; white race; later year of admission; in conjunction with comorbidities such as congestive heart failure, hypertension, chronic obstructive pulmonary disease, chronic renal and liver failure, sepsis, multiorgan dysfunction; and nonrural, medium/large hospitals, located in the Midwest, South, and West continental US location. Mortality after TBI decreased from 13% (95% CI, 12%–14%) in 1988 to 9% (95% CI, 9%–10%) in 2008 (P &lt; .001). ARDS/ALI-related mortality after TBI decreased from 33% (95% CI, 33%–34%) in 1988 to 28% (95% CI, 28%–29%) in 2008 (P &lt; .001). Predictors of in-hospital mortality after TBI were older age, male sex, white race, cancer, chronic kidney disease, hypertension, chronic liver disease, congestive heart failure, ARDS/ALI, and organ dysfunctions.CONCLUSION:Our analysis demonstrates that ARDS/ALI is common after TBI. Despite an overall reduction of in-hospital mortality, ARDS/ALI carries a higher risk of in-hospital death after TBI.


PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0246813
Author(s):  
Jacob B. Pierce ◽  
Nilay S. Shah ◽  
Lucia C. Petito ◽  
Lindsay Pool ◽  
Donald M. Lloyd-Jones ◽  
...  

Background Adults in rural counties in the United States (US) experience higher rates broadly of cardiovascular disease (CVD) compared with adults in urban counties. Mortality rates specifically due to heart failure (HF) have increased since 2011, but estimates of heterogeneity at the county-level in HF-related mortality have not been produced. The objectives of this study were 1) to quantify nationwide trends by rural-urban designation and 2) examine county-level factors associated with rural-urban differences in HF-related mortality rates. Methods and findings We queried CDC WONDER to identify HF deaths between 2011–2018 defined as CVD (I00-78) as the underlying cause of death and HF (I50) as a contributing cause of death. First, we calculated national age-adjusted mortality rates (AAMR) and examined trends stratified by rural-urban status (defined using 2013 NCHS Urban-Rural Classification Scheme), age (35–64 and 65–84 years), and race-sex subgroups per year. Second, we combined all deaths from 2011–2018 and estimated incidence rate ratios (IRR) in HF-related mortality for rural versus urban counties using multivariable negative binomial regression models with adjustment for demographic and socioeconomic characteristics, risk factor prevalence, and physician density. Between 2011–2018, 162,314 and 580,305 HF-related deaths occurred in rural and urban counties, respectively. AAMRs were consistently higher for residents in rural compared with urban counties (73.2 [95% CI: 72.2–74.2] vs. 57.2 [56.8–57.6] in 2018, respectively). The highest AAMR was observed in rural Black men (131.1 [123.3–138.9] in 2018) with greatest increases in HF-related mortality in those 35–64 years (+6.1%/year). The rural-urban IRR persisted among both younger (1.10 [1.04–1.16]) and older adults (1.04 [1.02–1.07]) after adjustment for county-level factors. Main limitations included lack of individual-level data and county dropout due to low event rates (<20). Conclusions Differences in county-level factors may account for a significant amount of the observed variation in HF-related mortality between rural and urban counties. Efforts to reduce the rural-urban disparity in HF-related mortality rates will likely require diverse public health and clinical interventions targeting the underlying causes of this disparity.


Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 4453-4453 ◽  
Author(s):  
Adeel M Khan ◽  
Alok A. Khorana

Abstract Background: Analysis of internet search traffic has provided a new proxy measure into the trends and patterns of patients' diseases and their information-seeking behaviors. In recent years, Google Trends has become a data resource of interest given its status as the largest internet search provider in the world with publicly-viewable, passively-collected, and expansive data on any searchable term or combination of terms. For instance, search terms related to influenza (e.g. fever) predicted influenza spread faster than standard surveillance as shown by Ginsberg et al in Nature 2009. The true outpatient burden and incidence of venous thromboembolism (VTE) has long been debated. Extant VTE data are limited to cases that present to medical attention, thus missing any cases that do not come to an emergency department or clinic. We hypothesized that Google Trends analysis offers potential insight into the general populations' blood clot burden and awareness. This study aimed to explore general trends of VTE-related terms and seasonal variation in searches. Methods: Google Trends was utilized to obtain relative search engine traffic values (defined as search volume indices, SVIs) for terms related to DVT in the United States from summer 2004 - winter 2015. Terms related to LEG SWELLING, CALF PAIN, VARICOSE VEINS, and LEG CLOT were used and combined with Boolean operators to combine similar terms. A separate search occurred for BLOOD CLOT and related terms to investigate awareness of VTEs. Analysis was performed in R (V3.1.1) in accordance with previously published Google Trends investigations. Results: The average relative volume of searches was highest for VARICOSE VEINS and lowest for LEG SWELLING by approximately 3.2 fold. A seasonal pattern was seen with summer months (May-Aug) having higher SVIs than winter months (Nov-Feb) for all terms in the 11 year study period except for BLOOD CLOT. Using a Wilcoxon signed rank test, mean SVI difference comparing summer to winter for LEG SWELLING showed W = 66 (p = 0.004), for CALF PAIN W = 66 (p = 0.003), for VARICOSE VEINS W = 67 (p = 0.004), and for LEG CLOT W = 65 (p = 0.005). For BLOOD CLOT, a gradual increase in SVIs was seen and characterized by a Mann-Kendall test as having a significant positive trend, S = 898, p = 0.024. Conclusions: Search terms related to VTE in the United States show a strong seasonal pattern with greater search activity in summer months compared to winters months. These data suggest a higher incidence and burden of VTE in the summer. This challenges previous notions of a weakly higher incidence of VTE in winter months, calculated as a relative risk of 1.143 by Dentali et al in 2011. The gradual increase in relative search traffic for BLOOD CLOT terms reflects a likely rising awareness and/or true rise in the incidence of VTEs in the United States from 2004-2015. Further studies should investigate whether internet search traffic correlates directly with total yearly DVT incidence rates. Keywords: Population, venous thromboembolism, incidence Figure 1. Figure 1. Figure 2. Figure 2. Disclosures Khorana: Leo Pharma: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Daiichi Sankyo: Consultancy, Honoraria; sanofi: Consultancy, Honoraria; Pfizer: Consultancy, Honoraria; Boehringer-Ingelheim: Consultancy, Honoraria.


2020 ◽  
Author(s):  
Young-Rock Hong ◽  
John Lawrence ◽  
Dunc Williams Jr ◽  
Arch Mainous III

BACKGROUND As the novel coronavirus disease (COVID-19) is widely spreading across the United States, there is a concern about the overloading of the nation’s health care capacity. The expansion of telehealth services is expected to deliver timely care for the initial screening of symptomatic patients while minimizing exposure in health care facilities, to protect health care providers and other patients. However, it is currently unknown whether US hospitals have the telehealth capacity to meet the increasing demand and needs of patients during this pandemic. OBJECTIVE We investigated the population-level internet search volume for telehealth (as a proxy of population interest and demand) with the number of new COVID-19 cases and the proportion of hospitals that adopted a telehealth system in all US states. METHODS We used internet search volume data from Google Trends to measure population-level interest in telehealth and telemedicine between January 21, 2020 (when the first COVID-19 case was reported), and March 18, 2020. Data on COVID-19 cases in the United States were obtained from the Johns Hopkins Coronavirus Resources Center. We also used data from the 2018 American Hospital Association Annual Survey to estimate the proportion of hospitals that adopted telehealth (including telemedicine and electronic visits) and those with the capability of telemedicine intensive care unit (tele-ICU). Pearson correlation was used to examine the relations of population search volume for telehealth and telemedicine (composite score) with the cumulative numbers of COVID-19 cases in the United States during the study period and the proportion of hospitals with telehealth and tele-ICU capabilities. RESULTS We found that US population–level interest in telehealth increased as the number of COVID-19 cases increased, with a strong correlation (<i>r</i>=0.948, <i>P</i>&lt;.001). We observed a higher population-level interest in telehealth in the Northeast and West census region, whereas the proportion of hospitals that adopted telehealth was higher in the Midwest region. There was no significant association between population interest and the proportion of hospitals that adopted telehealth (<i>r</i>=0.055, <i>P</i>=.70) nor hospitals having tele-ICU capability (<i>r</i>=–0.073, <i>P</i>=.61). CONCLUSIONS As the number of COVID-19 cases increases, so does the US population’s interest in telehealth. However, the level of population interest did not correlate with the proportion of hospitals providing telehealth services in the United States, suggesting that increased population demand may not be met with the current telehealth capacity. Telecommunication infrastructures in US hospitals may lack the capability to address the ongoing health care needs of patients with other health conditions. More practical investment is needed to deploy the telehealth system rapidly against the impending patient surge.


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