scholarly journals Effects of SARS CoV-2, COVID-19, and its vaccines on male sexual health and reproduction: where do we stand?

Author(s):  
Sharon P. Lo ◽  
Tung-Chin Hsieh ◽  
Alexander W. Pastuszak ◽  
James M. Hotaling ◽  
Darshan P. Patel

AbstractSince severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first discovered, there have been questions surrounding the effects of coronavirus disease 2019 (COVID-19), and more recently the COVID-19 vaccine, on men’s health and fertility. Significant research has been conducted to study viral tropism, potential causes for gender susceptibility, the impact of COVID-19 on male sexual function in the acute and recovery phases, and the effects of the virus on male reproductive organs and hormones. This review provides a recent assessment of the literature regarding the impact of COVID-19 and its vaccine on male sexual health and reproduction.

Author(s):  
Anna Fuchs ◽  
Aleksandra Matonóg ◽  
Joanna Pilarska ◽  
Paulina Sieradzka ◽  
Mateusz Szul ◽  
...  

Introduction: Coronavirus disease (COVID−19), announced as a pandemic by the World Health Organization, recently has dominated people’s lifestyle. The impact of COVID−19 seems to be relevant to the sexual health as well. Methods: This prospective study was conducted on two occasions involving 764 female patients between March and April 2020—before and during the time of social quarantine. The sexual function was assessed using the Polish version of the Female Sexual Function Index (FSFI). Every patient filled out the survey concerning socio-demographic characteristics as well as the influence of SARS-CoV−2 pandemic on their lives. Results: The overall FSFI score before the pandemic was 30.1 ± 4.4 and changed to 25.8 ± 9.7 during it. Scores of every domain: desire, arousal, lubrication, orgasm, satisfaction and pain decreased as well (p < 0.001). There was statistically significant association between the workplace and the change of FSFI scores before and during COVID−19 pandemic (p < 0.01). We noticed the biggest decrease in FSFI score in the group of women who did not work at all (5.2 ± 9.9). Religion had a statistically important impact on level of anxiety (p < 0.01). Conclusion: The main finding of our study was the influence of COVID−19 pandemic on the quality of sexual lifestyle and frequency of intercourse among Polish women.


2021 ◽  
Vol 15 (12) ◽  
Author(s):  
Benjamin Shiff ◽  
Udi Blankstein ◽  
Jafar Hussaen ◽  
Keith Jarvi ◽  
Ethan Grober ◽  
...  

Introduction: Despite increasing consumption rates in much of the world, the impact of cannabis use on various components of male sexual function remain poorly established. The purpose of this study was to further evaluate the relationship between cannabis use and reproductive and sexual function using a large patient cohort from a single academic andrology clinic. Methods: This is a historical cohort study from a single academic center andrology clinic. Patients from 2008–2017 were included. Intake questionnaires provided baseline demographic information, as well as data regarding substance use and various sexual function parameters. Subjects were categorized as cannabis users or non-users. Cannabis users and non-users were compared using descriptive statistics and Chi-squared tests, and regression analyses were performed to test for association. Results: A total of 7809 males were included in the study; 993 (12.7%) were cannabis users and 6816 (87.3%) were non-users. Cannabis users had a higher mean Sexual Health Inventory for Men (SHIM) score (21.94.4 vs. 21.24.8, p<0.001) and mean serum total testosterone (13.412.0 nmol/L vs. 12.611.8 nmol/L, p=0.04) than non-users, although they also had a higher rate of positive Androgen Deficiency in the Aging Male (ADAM) scores (52% vs. 46%, p<0.001). Cannabis users also reported higher sexual frequency compared to non-users (8.8 events/month vs. 7.8 events/month, p<0.05). On multivariate analysis, cannabis use was not associated with SHIM score or serum testosterone concentration. Cannabis use was associated with positive ADAM scores. Conclusions: Cannabis use was not associated with clinically significant deleterious effects on male sexual parameters in this cohort.


2014 ◽  
Vol 5 (3) ◽  
pp. 183-188 ◽  
Author(s):  
C. Dupont ◽  
D. Ralliard-Rousseau ◽  
A. Tarrade ◽  
C. Faure ◽  
M. Dahirel ◽  
...  

The concept of Developmental Origins of Health and Disease initially stemmed from the developmental programming of metabolic diseases. Reproductive functions and fertility in adulthood may also be programmed during foetal development. We studied the impact of dietary-induced maternal hyperlipidaemia and hypercholesterolaemia (HH), administered at 10 weeks of age and throughout the gestation and lactation, on male reproductive functions of rabbit offspring. Male rabbits born to HH dams and fed a control diet had significantly lighter testes and epididymes compared with rabbits born to control dams at adulthood. No significant changes in sperm concentration, sperm DNA integrity and sperm membrane composition were observed, but serum-free testosterone concentrations were decreased in HH males. This study confirms the importance of maternal metabolic status for the development of male reproductive organs.


2017 ◽  
Vol 16 (13) ◽  
pp. e3021
Author(s):  
A. Zachariou ◽  
M. Filiponi ◽  
F. Dimitriadis ◽  
I. Giannakis ◽  
P. Lantin ◽  
...  

2010 ◽  
Vol 33 (2) ◽  
pp. 74-76 ◽  
Author(s):  
J. Elia ◽  
M. Delfino ◽  
N. Imbrogno ◽  
F. Mazzilli

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