scholarly journals The Predictive Value of Head Circumference Growth during the First Year of Life on Early Child Traits

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Caroline Dupont ◽  
Natalie Castellanos-Ryan ◽  
Jean R. Séguin ◽  
Gina Muckle ◽  
Marie-Noëlle Simard ◽  
...  
Keyword(s):  
Head Circumference ◽  
Predictive Value ◽  
First Year ◽  
Early Child ◽  
First Year Of Life

Prenatal Sonographic Head Circumference and Cerebral Ventricle Width Measurements Before and After Open Fetal Myelomeningocele Repair – Prediction of Shunting During the First Year of Life

2018 ◽  
Vol 41 (05) ◽  
pp. 544-549 ◽  
Author(s):  
Ladina Vonzun ◽  
Franziska Maria Winder ◽  
Martin Meuli ◽  
Ueli Moerlen ◽  
Luca Mazzone ◽  
...  
Keyword(s):  
Head Circumference ◽  
Predictive Accuracy ◽  
False Positive Rate ◽  
Roc Curves ◽  
First Year ◽  
Fetal Head ◽  
Fetal Diagnosis ◽  
Before And After ◽  
Width Measurements ◽  
First Year Of Life

Abstract Purpose The aim of this study was to describe the sonographic evolution of fetal head circumference (HC) and width of the posterior horn of the lateral ventricle (Vp) after open fetal myelomeningocele (fMMC) repair and to assess whether pre- or postoperative measurements are helpful to predict the need for shunting during the first year of life. Patients & Methods All 30 children older than one year by January 2017 who previously had fMMC repair at the Zurich Center for Fetal Diagnosis and Therapy were included. Sonographic evolution of fetal HC and Vp before and after fMMC repair was assessed and compared between the non-shunted (N = 16) and the shunted group (N = 14). ROC curves were generated for the fetal HC Z-score and Vp in order to show their predictive accuracy for the need for shunting until 1 year of age. Results HC was not an independent factor for predicting shunting. However, the need for shunting was directly dependent on the preoperative Vp as well as the Vp before delivery. A Vp > 10 mm at evaluation for fMMC repair or > 15 mm before delivery identifies 100 % of the infants needing shunt placement at a false-positive rate of 44 % and 25 %, respectively. All fetuses with a Vp > 15 mm at first evaluation received a shunt. Conclusion Fetuses demonstrating a Vp of > 15 mm before in utero MMC repair are extremely likely to develop hydrocephalus requiring a shunt during the first year of life. This compelling piece of evidence must be appropriately integrated into prenatal counseling.

scholarly journals Human Milk Glucocorticoid Levels Are Associated With Infant Adiposity and Head Circumference Over the First Year of Life

2020 ◽  
Vol 7 ◽  
Author(s):  
Shikha Pundir ◽  
Zoya Gridneva ◽  
Avinesh Pillai ◽  
Eric B. Thorstensen ◽  
Clare R. Wall ◽  
...  
Keyword(s):  
Human Milk ◽  
Head Circumference ◽  
First Year ◽  
First Year Of Life

scholarly journals Evaluation of the Liaison Automated Testing System for Diagnosis of Congenital Toxoplasmosis

2012 ◽  
Vol 19 (11) ◽  
pp. 1859-1863 ◽  
Author(s):  
Andrea-Romana Prusa ◽  
Michael Hayde ◽  
Arnold Pollak ◽  
Kurt R. Herkner ◽  
David C. Kasper
Keyword(s):  
Predictive Value ◽  
Congenital Toxoplasmosis ◽  
Congenital Infection ◽  
Confirmatory Test ◽  
Diagnostic Tools ◽  
First Year ◽  
Study Cohort ◽  
Serum Samples ◽  
Content Type ◽  
First Year Of Life

ABSTRACTCongenital toxoplasmosis is a worldwide health problem, and different screening strategies exist. Testing of toxoplasma-specific antibodies in infants identifies congenital toxoplasmosis during the first year of life. However, experience with commercial available immunoassays is limited. The aim of this study was to evaluate both the performance and analytical characteristics of the Liaison diagnostic system in infants. In a retrospective study, serumToxoplasma gondiiantibodies were measured in samples from 333 infants, including 212 noninfected infants and 121 infants with congenital toxoplasmosis. A total of 1,157 umbilical cord blood and peripheral serum samples were analyzed. Liaison toxoplasma-specific IgG and IgM antibodies and the IgG avidity index were compared to the infection status of the infant, determined by the Sabin-Feldman dye test and immunosorbent agglutination assay—IgM. All noninfected infants were seronegative by Liaison IgG within the first year of life. The Liaison system showed a sensitivity of 81.8%, a specificity of 100.0%, a positive predictive value of 100.0%, a negative predictive value of 90.6%, and overall agreement of 84.4% by comparison with the dye test. Overall agreement of both IgM test systems was 96.0%. In this study cohort, avidity did not show a potential diagnostic benefit for the detection of congenital infection. In conclusion, the Liaison system is a valuable tool to monitor the serologic course of infants at risk. A final serologic confirmatory test is recommended to improve the rate of detection of congenital toxoplasmosis at 1 year of life. Protocols of routine follow-up testing in infants and accurate diagnostic tools after acute gestational infections are needed to improve medical care.

Autism and head circumference in the first year of life

2004 ◽  
Vol 56 (11) ◽  
pp. 892-894 ◽  
Author(s):  
E. Fuller Torrey ◽  
Dawn Dhavale ◽  
John P. Lawlor ◽  
Robert H. Yolken
Keyword(s):  
Head Circumference ◽  
First Year ◽  
First Year Of Life

scholarly journals A computed tomography scoring system to assess pulmonary disease among premature infants

2010 ◽  
Vol 128 (6) ◽  
pp. 328-335 ◽  
Author(s):  
Márcia Cristina Bastos Boechat ◽  
Rosane Reis de Mello ◽  
Kátia Silveira da Silva ◽  
Pedro Daltro ◽  
Edson Marchiori ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Premature Infants ◽  
Predictive Value ◽  
Scoring System ◽  
Intraclass Correlation ◽  
Pulmonary Involvement ◽  
Respiratory Morbidity ◽  
First Year ◽  
High Resolution Computed Tomography ◽  
First Year Of Life

CONTEXT AND OBJECTIVE: High-resolution computed tomography (HRCT) is considered to be the best method for detailed pulmonary evaluation. The aim here was to describe a scoring system based on abnormalities identified on HRCT among premature infants, and measure the predictive validity of the score in relation to respiratory morbidity during the first year of life. DESIGN AND SETTING: Prospective cohort study in Instituto Fernandes Figueira, Fundação Oswaldo Cruz. METHODS: Scoring system based on HRCT abnormalities among premature newborns. The affected lung area was quantified according to the number of compromised lobes, in addition to bilateral pulmonary involvement. Two radiologists applied the score to 86 HRCT scans. Intraobserver and interobserver agreement were analyzed. The score properties were calculated in relation to predictions of respiratory morbidity during the first year of life. RESULTS: Most of the patients (85%) presented abnormalities on HRCT, and among these, 56.2% presented respiratory morbidity during the first year of life. Scores ranged from zero to 12. There was good agreement between observers (intraclass correlation coefficient, ICC = 0.86, confidence interval, CI: 0.64-0.83). The predictive scores were as follows: positive predictive value 81.8%, negative predictive value 56.3%, sensitivity 39.1%, and specificity 90.0%. CONCLUSION: The scoring system is reproducible, easy to apply and allows HRCT comparisons among premature infants, by identifying patients with greater likelihood of respiratory morbidity during the first year of life. Its use will enable HRCT comparisons among premature infants with different risk factors for respiratory morbidity.

scholarly journals THE EFFECT OF DIFFERENT TYPES OF FEEDING ON THE BASIC PARAMETERS OF PHYSICAL DEVELOPMENT OF INFANTS LIVING IN GOMEL DURING THEIR FIRST YEAR OF LIFE

2017 ◽  
pp. 44-49
Author(s):  
A. A. Kozlovsky ◽  
V. A. Melnik ◽  
E. V. Kurashevich ◽  
A. A. Kozlovsky1 (Jr) ◽  
E. O. Lopatenko
Keyword(s):  
Body Mass ◽  
Body Length ◽  
Head Circumference ◽  
Physical Development ◽  
Chest Circumference ◽  
First Year ◽  
Term Infants ◽  
Different Types ◽  
Basic Parameters ◽  
First Year Of Life

Aim of research: to carry out comparative assessment of monthly gains of length, body mass, head circumference, and chest circumference in healthy full-term infants during their first year of life receiving different types of feeding. Material and methods of research. We have analyzed monthly gains of the basic parameters of physical development of 200 full-term infants by the results of the retrospective survey of histories of infant development performed at Branch No. 3 of state health institution «Gomel City Central Children`s Out-Patient Clinic». Results. We have revealed accelerated gains of body mass, head circumference, and chest circumference in the first quarter and some lag of these parameters in other periods (as compared to the parameters recommended by the WHO). At the same time, the gain of body length practically did not differ from the standard one. On the whole, the average gains of body mass and body length, head circumference, and chest circumference in most the infants by 12 months did not differ from the standard ones. Only the girls receiving artificial feeding noted an inadequate gain of body length in comparison with the standard one (22.34 and 25 см correspondingly; -10.6 %), and those who were receiving natural feeding detected a decrease of the average gain of chest circumference by 10.4 %. Conclusion. We have found uneven rates of gains of the basic parameters of physical development in contemporary infants during their first year of life which do not depend on the type of feeding.

Early Identification of Cerebral Palsy Using a Profile of Abnormal Motor Patterns

PEDIATRICS ◽  
1996 ◽  
Vol 98 (4) ◽  
pp. 692-697
Author(s):  
Andrew M. Morgan ◽  
Jean C. Aldag
Keyword(s):  
Cerebral Palsy ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
First Year ◽  
Cutoff Score ◽  
Optimal Cutoff ◽  
Motor Patterns ◽  
Health Maintenance ◽  
First Year Of Life ◽  
Abnormal Motor

Objective. To determine whether a profile of abnormal motor patterns can identify children with cerebral palsy (CP) in the first year of life. Methods. The Early Motor Pattern Profile (EMPP) consists of 15 items reflecting variations in muscle tone, reflexes, and movement that have been organized into a standardized format to provide the clinician with an objective picture of neurologic status. A three-point scoring system was applied to each item, delineating a clearly normal response from a clearly abnormal one and placing all partial or inconsistent responses in the middle. Twelve hundred forty-seven high-risk infants who were enrolled in a neonatal intensive care unit follow-up program were examined at 6 and/or 12 months' corrected age using the EMPP. These infants were followed to at least 36 months of age to distinguish those with CP from those with normal motor outcome or minimal impairment (no CP). Results. Predictive validity of the EMPP at the 6- and 12-month examinations was determined using various pass-fail cutoffs. The optimal cutoff score at 6 months was between 9 and 10, at which the positive predictive value was 89.4, sensitivity was 87.1, and specificity was 97.8. The optimal cutoff score at 12 months was between 3 and 4, at which the positive predictive value was 91.0, sensitivity was 91.5, and specificity was 97.9. Conclusions. The EMPP offers the clinician an effective instrument to identify children in the first year of life who are at greatest risk for the development of CP. The EMPP can be incorporated into a routine health maintenance visit, adding only a few minutes to the process, and has high sensitivity and specificity.

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