Efficacy and safety of 3D printing-assisted percutaneous nephrolithotomy in complex renal calculi

AbstractThis study evaluated the efficacy and safety of 3D printing technology combined with percutaneous nephrolithotomy in the treatment of complex renal calculi. Ninety patients with complex renal calculi were randomly divided into a 3D printing group (45 patients) and a control group (45 patients). In the 3D printing group, a patient-specific 1:1 3D printing model was established based on the patient's thin-layer CT scanning data. A 3D printing model was used for preoperative communication between doctors and patients. Preoperative puncture training, channel design, residual stone prediction, and percutaneous nephrolithotomy were performed under the guidance of a 3D printing model and B-ultrasound. The control group was treated with the conventional B-ultrasound-guided puncture method. Results suggest that there was a statistically significant difference between the two groups (P < 0.05). The overall score of the doctor-patient communication objects in the 3D printing group was 19.32 ± 1.57 points, and in the control group, it was 14.51 ± 2.13 points. The operation time of the 3D printing group was 103.21 ± 13.49 min, and that of the control group was 126.12 ± 25.87 min. The calculi clearance rate of the 3D printing group was 96%, while that of the control group was 80%. The incidence of postoperative complications was 6.67% in the 3D printing group and 22.22% in the control group. Compared with traditional percutaneous nephrolithotomy, 3D printing technology combined with percutaneous nephrolithotomy can significantly enhance the effectiveness of doctor–patient communication, shorten operation time, reduce operation bleeding, improve the stone clearance rate, reduce the incidence of complications and shorten the length of hospital stay. The proposed method is thus a safe and effective method to treat complex renal calculi.

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A 3D Printing Personalized Percutaneous Nephroscope Puncture Guide Plate in Percutaneous Nephrolithotomy: A Pilot Study

10.21203/rs.3.rs-724657/v1 ◽

2021 ◽

Author(s):

Gao Keyu ◽

Li Shuaishuai ◽

Ashok raj ◽

Li Shuofeng ◽

Liu Shuai ◽

...

Keyword(s):

3D Printing ◽

Blood Loss ◽

Percutaneous Nephrolithotomy ◽

Color Doppler ◽

Control Group ◽

Intraoperative Blood Loss ◽

Printing Technology ◽

3D Printing Technology ◽

Guide Plate ◽

Significant Difference

Abstract Objective Using CTU, combined with 3D printing technology, digital design, the development of individualized PCNL) puncture guides, preliminary discussion of its feasibility for PCNL puncture positioning.Methods Twenty-two patients with renal calculi who underwent PCNL in the hospital of Xuzhou Medical University in 2017-2018, including 10 experimental groups, used 3D printing technology to make guides (puncture guides); simulated punctures in vitro, after clearing the needle angle, PCNL was performed in 10 patients and PCNL in 12 patients in the control group. The accuracy of puncture positioning, puncture time and intraoperative blood loss were compared between the two groups.Results In the experimental group, 10 patients had good puncture guide plate and the patient's skin. The puncture needle was puncture under the guidance of the guide plate and verified by the color Doppler. The 1 needle puncture was successful 100.00% (10/10), the positioning of the needle point, the depth of the puncture. The angles were consistent with the preoperative design. The success rate of 12 cases of color Doppler ultrasound in the control group was 75.00% (9/12). There was no significant difference between the two groups (P>0.05). The amount of hemorrhage was (7.78±0.94) min and (49.31±6.43) mL, respectively. The control group was (9.04±1.09) min and (60.08±12.18) mL, respectively. The two groups were statistically significant (P<0.05). Conclusion 3D printing personalized percutaneous nephrolithotomy guide can improve the accuracy of PCNL renal puncture channel positioning, shorten the puncture time and reduce intraoperative blood loss, and provide a new method for PCNL renal puncture positioning, which is worthy of further clinical exploration.

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Traditional versus mirror three-dimensional printing technology for isolated acetabular fractures: a retrospective study with a median follow-up of 25 months

Journal of International Medical Research ◽

10.1177/03000605211028554 ◽

2021 ◽

Vol 49 (6) ◽

pp. 030006052110285

Author(s):

Kai Xiao ◽

Bo Xu ◽

Lin Ding ◽

Weiguang Yu ◽

Lei Bao ◽

...

Keyword(s):

3D Printing ◽

Three Dimensional ◽

Operation Time ◽

Harris Hip Score ◽

Acetabular Fractures ◽

Printing Technology ◽

Three Dimensional Printing ◽

3D Printing Technology ◽

Significant Difference

Objective To assess the outcomes of traditional three-dimensional (3D) printing technology (TPT) versus mirror 3D printing technology (MTT) in treating isolated acetabular fractures (IAFs). Methods Consecutive patients with an IAF treated by either TPT or MTT at our tertiary medical centre from 2012 to 2018 were retrospectively reviewed. Follow-up was performed 1, 3, 6, and 12 months postoperatively and annually thereafter. The primary outcome was the Harris hip score (HHS), and the secondary outcomes were major intraoperative variables and key orthopaedic complications. Results One hundred fourteen eligible patients (114 hips) with an IAF (TPT, n = 56; MTT, n = 58) were evaluated. The median follow-up was 25 months (range, 21–28 months). At the last follow-up, the mean HHS was 82.46 ±14.70 for TPT and 86.30 ± 13.26 for MTT with a statistically significant difference. Significant differences were also detected in the major intraoperative variables (operation time, intraoperative blood loss, number of fluoroscopic screenings, and anatomical reduction number) and the major orthopaedic complications (loosening, implant failure, and heterotopic ossification). Conclusion Compared with TPT, MTT tends to produce accurate IAF reduction and may result in better intraoperative variables and a lower rate of major orthopaedic complications.

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Application of Three-dimensional Visualization assisted Ultrasound for Percutaneous Renal Puncture

10.21203/rs.3.rs-113148/v1 ◽

2020 ◽

Author(s):

Zhibin Xu ◽

Zhenchi Li ◽

Maomao Guo ◽

Hao Bian ◽

Tianli Niu ◽

...

Keyword(s):

Clearance Rate ◽

3D Visualization ◽

Three Dimensional ◽

Operation Time ◽

Control Group ◽

Transfusion Rate ◽

Stone Clearance ◽

Time Operation ◽

Postoperative Blood Transfusion ◽

Experimental Group

Abstract We present here the three-dimensional (3D) visualization fused with ultrasound and to evaluate its clinical application effect preliminarily. One hundred and eighteen patients with renal calculi in our hospital from September 2017 to December 2019 were prospectively randomized into two groups. The experimental group was treated with percutaneous renal puncture guided by the 3D visualization fused with ultrasound. The control group was treated with percutaneous renal puncture guided by B-ultrasonography (B-US). The puncture time, operation time, and the loss of hemoglobin in the experimental group were lower than those in the control group, and the success rate of establishing the channel at one time, and the coincidence rate between the channel and the longitudinal axis of the target renal calyx were higher. The stone clearance rate in the experimental group was higher, while the postoperative blood transfusion rate and interventional embolization rate in the experimental group were significantly lower. The difference was statistically significant (P < 0.05). 3D visualization assisted ultrasound could preliminarily guide precise navigation to puncture tissues, reduced operation time and bleeding, improved stone clearance rate and operation safety.

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V6-04 FULL IMMERSION SIMULATED PERCUTANEOUS NEPHROLITHOTOMY USING 3D PRINTING TECHNOLOGY

The Journal of Urology ◽

10.1016/j.juro.2016.02.404 ◽

2016 ◽

Vol 195 (4S) ◽

Author(s):

Jonathan Stone ◽

Alexander Fidalgo ◽

Jennifer Park ◽

Braden Candela ◽

Doran Mix ◽

...

Keyword(s):

3D Printing ◽

Percutaneous Nephrolithotomy ◽

Printing Technology ◽

3D Printing Technology ◽

Full Immersion

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Comparing the Effectiveness of 3D Printing Technology in the Treatment of Clavicular Fracture between Surgeons with Different Experiences

10.21203/rs.3.rs-940167/v1 ◽

2021 ◽

Author(s):

Jiang long Guo ◽

Hong yi Li ◽

Kui Zhao ◽

Meng Zhang ◽

Jing zhi Ye ◽

...

Keyword(s):

3D Printing ◽

Standard Dose ◽

Operation Time ◽

3D Models ◽

P Value ◽

Printing Technology ◽

3D Printing Technology ◽

Value Range ◽

Group A ◽

Group B

Abstract Purpose To comparethe effectiveness of the three-dimensional (3D) printing technology in the treatment of clavicularfracturebetween experienced and inexperienced orthopedic surgeons. Methods A total of 80 patients with clavicle fracture (from February 2017 to May 2021)were enrolled in our study. Patients were divided randomly into four groups: group A: Patients underwent low-dose CT scan and 3D models were printed before surgeries performed by inexperienced surgeons; group B: Standard-dose CT were taken and 3D models were printed before surgeries performed by experienced surgeons; group C and D: Standard-dose CT were taken in both groups, and the operations were performed differently by inexperienced (group C) and experienced (group D) surgeons. Operation time, blood loss, length of incision and number of intraoperative fluoroscopy were recorded. Results No statistically significant differences were found in age, gender, fracture site and fracture type (P value: 0.23–0.88).Group A showed shorter incision length and less intraoperative fluoroscopy times than group C and D (P value < 0.05). There were no significant differences in blood loss volume, incision length and number of intraoperative time between group A and group B (P value range: 0.11–0.28). The operation time of group A was no longer than that of group C and D (P value range: 0.11 and 0.24). Conclusion The surgical effectiveness of inexperienced surgeons who applied 3D printing technology before clavicular fracture operation were better than those of both inexperienced and experienced surgeons did not use preoperative 3D printing technology.

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3D printing technology in percutaneous nephrolithotomy: babyhood but will be promising

World Journal of Urology ◽

10.1007/s00345-019-03068-z ◽

2020 ◽

Vol 38 (12) ◽

pp. 3303-3303 ◽

Cited By ~ 1

Author(s):

Weizhou Wu ◽

Zhijian Zhao ◽

Shike Zhang ◽

WenQi Wu

Keyword(s):

3D Printing ◽

Percutaneous Nephrolithotomy ◽

Printing Technology ◽

3D Printing Technology

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Therapeutic Efficacy of Artificial Skin Produced by 3D Bioprinting

Materials ◽

10.3390/ma14185177 ◽

2021 ◽

Vol 14 (18) ◽

pp. 5177

Author(s):

Kwang-Sik Jang ◽

Soon-Jung Park ◽

Jong-Jin Choi ◽

Ha-Na Kim ◽

Kyung-Mi Shim ◽

...

Keyword(s):

3D Printing ◽

Healing Process ◽

Skin Layer ◽

The Body ◽

Control Group ◽

Wound Healing Process ◽

Therapeutic Effects ◽

Skin Substitutes ◽

Printing Technology ◽

3D Printing Technology

The skin protects the body from external barriers. Certain limitations exist in the development of technologies to rapidly prepare skin substitutes that are therapeutically effective in surgeries involving extensive burns and skin transplantation. Herein, we fabricated a structure similar to the skin layer by using skin-derived decellularized extracellular matrix (dECM) with bioink, keratinocytes, and fibroblasts using 3D-printing technology. The therapeutic effects of the produced skin were analyzed using a chimney model that mimicked the human wound-healing process. The 3D-printed skin substitutes exhibited rapid re-epithelialization and superior tissue regeneration effects compared to the control group. These results are expected to aid the development of technologies that can provide customized skin-replacement tissues produced easily and quickly via 3D-printing technology to patients.

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Percutaneous nephrolithotomy assisted by LithoClast master in one-phase treatment for staghorn renal stones with refractory infections

10.21203/rs.3.rs-38642/v1 ◽

2020 ◽

Author(s):

Hai-Xiao Tang ◽

Di Wu ◽

Bo-Wen Shi ◽

Ze-Hao Dai ◽

Yun-Teng Huang

Keyword(s):

Percutaneous Nephrolithotomy ◽

Medical Center ◽

Operation Time ◽

Renal Stones ◽

Efficacy And Safety ◽

Medical Systems ◽

Two Phase ◽

Reactive Protein ◽

Fifth Generation ◽

Grade Ii

Abstract Background: Infectious staghorn renal stones are usually treated with one-phase for percutaneous puncture and drainage, and then two-phase for percutaneous nephrolithotomy (PCNL). The objective of the study was to evaluate the efficacy and safety of PCNL assisted by LithoClast master (the fifth-generation Electro Medical Systems, EMS) in one-phase treatment for staghorn renal stones with refractory infections.Methods: From September 2017 to September 2019, 80 patients with staghorn renal stones who underwent one-phase for PCNL combined with the fifth-generation EMS in our hospital were retrospectively analyzed. According to whether patients with staghorn renal stones were complicated with refractory infections or not before operation, they were divided into A group (48 cases with refractory infections) and B group (32 cases without infections). In A group, refractory infections were properly controlled with sensitive antibiotics before operation. The efficacy and safety of treatment for two groups were compared.Results: Before taking sensitive antibiotics in A group, there was statistical difference in the location of stones between the two groups (P＜0.05), while there were no statistical significances in other general clinical data between the two groups (P＞0.05). Although there were statistical differences in the increase rate of white blood cell count, C-reactive protein, procalcitonin on the first day after operation between the two groups (P＜0.05), there were no statistical differences in operation time, hospitalization time, hemoglobin, stone-free rate, Clavien-Dindo grade I complications, Clavien-Dindo grade II and above complications between the two groups (P＞0.05). Conclusions: For staghorn renal stones with refractory infections, based on the application of sensitive antibiotics before operation to properly control refractory infections, PCNL assisted by the fifth-generation EMS in one-phase can efficiently remove staghorn renal stones, without increasing the risk of postoperative complications. In the medical center with mature technical conditions and rich experience, staghorn renal stones with refractory infections can be selected carefully to carry out one-phase operation.

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Study on the Application Value of CT Thin-Layer Scan Data Assisted 3D Printing Technology in Hip and Knee Replacement

Journal of Healthcare Engineering ◽

10.1155/2021/3491509 ◽

2021 ◽

Vol 2021 ◽

pp. 1-7

Author(s):

Shihua Sun ◽

Yongbin Xi ◽

Xingchen Shi ◽

Li Zhao ◽

Fuming Ma ◽

...

Keyword(s):

3D Printing ◽

Thin Layer ◽

Knee Replacement ◽

Operation Time ◽

Printing Technology ◽

3D Printing Technology ◽

Actual Application ◽

Loss Of Reduction ◽

Scan Data ◽

Ankle Function

To better study hip and knee replacement, 50 eligible hip and knee patients from March 2020 to April 2021 were selected. A 1 : 1 scale solid model was printed with CT thin-layer scanning data assisted by 3D printing technology to evaluate the ankle function of patients six months after surgery. The results showed that the 3D rapid prototyping time of the 1 : 1 fracture model in 50 patients was 3-4 hours. The operation time was 70–90 min, and the average operation time was 80 min. The actual application in operation was consistent with that in the simulation of the 3D printing model, after surgery, and there was no infection of incision soft tissue or loss of reduction in all 50 patients. CT thin-layer scan data aided 3D printing technology can help clinical hip and knee replacement simulation and planning, improving surgery’s accuracy and safety.

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A 3D printing personalized percutaneous puncture guide access plate for percutaneous nephrolithotomy: a pilot study

BMC Urology ◽

10.1186/s12894-021-00945-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Gao Keyu ◽

Li Shuaishuai ◽

Ashok Raj ◽

Li Shuofeng ◽

Liu Shuai ◽

...

Keyword(s):

3D Printing ◽

Blood Loss ◽

Success Rate ◽

Percutaneous Nephrolithotomy ◽

Control Group ◽

Intraoperative Blood Loss ◽

Percutaneous Puncture ◽

Puncture Needle ◽

Guide Plate ◽

Group 12

Abstract Objective CT-Urography combined with 3D printing technology, digital design, construction of individualized PCNL puncture guides, and preliminary analyze their efficacy, safety puncture positioning for PCNL. Methods Twenty-two patients with renal calculi were randomly selected at the affiliated Hospital of Xuzhou Medical University during 2017–2018. We randomly divided the patients into two groups: in 10 experimental groups, we used our 3D printing personalized percutaneous puncture guide access plate for PCNL, and in the control group, 12 patients with standard USG guide PCNL. The accuracy of puncture position, puncture time, and intraoperative blood loss was compared. Results In the experimental group, 10 patients with 3D printing personalized percutaneous puncture guide access plate. The puncture needle was accessed through the guide plate and verified by the color Doppler. The single puncture, needle position, and depth success rate were 100.00% (10/10). The angles were consistent with the preoperative design. In the control group, 12 patients via USG guided PCNL success rate was 75.00% (9/12). The puncture time and amount of hemorrhage was (7.78 ± 0.94) min and (49.31 ± 6.43) mL, and (9.04 ± 1.09) min and (60.08 ± 12.18) mL, respectively. The above data of the two groups were statistically significant (P < 0.05). Conclusion 3D printing personalized percutaneous nephrolithotomy guide plate for PCNL can improve PCNL renal puncture channel positioning accuracy, shorten puncture time, reduce intraoperative blood loss, bleeding-related complications and provide a new method for PCNL renal puncture positioning, which is worthy of further clinical exploration.

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