scholarly journals Provocation of dry eye disease symptoms during COVID-19 lockdown

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nutnicha Neti ◽  
Pinnita Prabhasawat ◽  
Chareenun Chirapapaisan ◽  
Panotsom Ngowyutagon
Keyword(s):  
Mental Health ◽  
Health Status ◽  
Dry Eye ◽  
Visual Display ◽  
Dry Eye Disease ◽  
Mental Health Status ◽  
Eye Disease ◽  
Eye Symptoms ◽  
The Mean ◽  
Dry Eye Symptoms

AbstractTo assess the impact of COVID-19 lockdown measures on dry-eye symptoms in a community-based population, a cross-sectional study was conducted during the first wave of the COVID-19 outbreak in Thailand. An online survey was distributed via social media between June and July 2020. The questionnaire elicited information on demographics, dry-eye symptoms, use of visual display terminals, and mental health status. There were 535 respondents. Thirty-seven percent reported having been diagnosed with dry-eye disease (DED). During the lockdown, the mean dry-eye symptom score (DESS) of overall participants dropped significantly from 81.6 ± 15.9 to 79.8 ± 17.4 (P < 0.001). The mean, daily, visual display terminal (VDT) usage increased from 10.55 ± 5.16 to 13.08 ± 5.65 h (P < 0.001). A negative correlation between age and VDT usage was observed in both the normal and lockdown situations. One-quarter of all participants had an abnormal mental health status. The female gender (OR 1.86; 95% CI 1.14–3.04) and increased VDT usage during the lockdown (OR 5.68; 95% CI 3.49–9.23) were independently associated with worsening dry-eye symptoms. The lockdown measures abruptly altered the behaviors and lifestyles of the overall population. Excessive exposure to VDTs were associated with deteriorated dry-eye symptoms, and it possibly contributed to the increased DED incidence in the surveyed population.

scholarly journals Provocation of Dry Eye Disease during COVID-19 Lockdown

2021 ◽  
Author(s):  
Nutnicha Neti ◽  
Pinnita Prabhasawat ◽  
Chareenun Chirapapaisan ◽  
Panotsom Ngowyutagon
Keyword(s):  
Mental Health ◽  
Health Status ◽  
Dry Eye ◽  
Dry Eye Disease ◽  
Mental Health Status ◽  
Eye Disease ◽  
Eye Symptoms ◽  
The Mean ◽  
The Impact ◽  
Dry Eye Symptoms

Abstract To assess the impact of COVID-19 lockdown measures on dry-eye symptoms in a community-based population, a cross-sectional study was conducted during the first wave of the COVID-19 outbreak in Thailand. An online survey was distributed via social media between June and July 2020. The questionnaire elicited information on demographics, dry-eye symptoms, viewing habits, and mental health status. There were 535 respondents. Thirty-seven percent reported having been diagnosed with dry-eye disease (DED). During the lockdown, the mean dry-eye symptom score (DESS) of overall participants dropped significantly from 81.6±15.9 to 79.8±17.4 (P<0.001). The mean, daily, visual display terminal (VDT) usage increased from 10.55±5.16 hours to 13.08±5.65 hours (P<0.001). A negative correlation between age and VDT usage was observed in both the normal and lockdown situations. One-quarter of all participants had an abnormal mental health status. The female gender (OR 1.86; 95% CI 1.14–3.04) and increased VDT usage during the lockdown (OR 5.68; 95% CI 3.49–9.23) were independently associated with worsening dry-eye symptoms. The lockdown measures abruptly altered the behaviors and lifestyles of the overall population. Excessive exposure to VDTs were associated with deteriorated dry-eye symptoms, and it possibly contributed to the increased DED incidence in the general population.

scholarly journals Mental Health Status in Dry Eye Disease – a Case Control Study

2018 ◽  
Vol 12 (1) ◽  
pp. 56 ◽  
Author(s):  
Luxmi Singh ◽  
Vijay Pratap Singh ◽  
Swati Yadav ◽  
Pragati Garg ◽  
◽  
...  
Keyword(s):  
Mental Health ◽  
Health Status ◽  
Dry Eye ◽  
Case Control Study ◽  
Case Control ◽  
Dry Eye Disease ◽  
Mental Health Status ◽  
Eye Disease ◽  
Control Study

Dry eye disease, dry eye symptoms and depression: the Beijing Eye Study

2013 ◽  
Vol 97 (11) ◽  
pp. 1399-1403 ◽  
Author(s):  
Antoine Labbé ◽  
Ya Xing Wang ◽  
Ying Jie ◽  
Christophe Baudouin ◽  
Jost B Jonas ◽  
...  
Keyword(s):  
Dry Eye ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Beijing Eye Study ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

scholarly journals Case finding of dry eye disease in Norwegian optometric practice: a cross-sectional study

2021 ◽  
Vol 14 (1) ◽  
pp. 1-6
Author(s):  
Ann Elisabeth Ystenæs ◽  
Ingeborg Sand ◽  
Vibeke Sundling
Keyword(s):  
Dry Eye ◽  
Contact Lens ◽  
Cross Sectional Study ◽  
Case Finding ◽  
Eye Disease ◽  
Cross Sectional ◽  
Eye Symptoms ◽  
The Mean ◽  
Breakup Time ◽  
Dry Eye Symptoms

Optometrists are primary eye care providers, and it is essential that they efficiently identify patients who will benefit from dry eye management. The aim of the study was to explore case finding of dry eye disease (DED) in optometric practice. A cross-sectional study examining dry eye symptoms and signs in 186 patients (18–70 years of age) attending a routine eye examination, with DED defined according to the criteria of the Tear Film and Ocular Surface Society Dry Eye Workshop II. Standard statistical tests were used, and clinical diagnostics were explored using sensitivity, specificity, and receiveroperating curve (ROC) statistics. Fifty-six patients were contact lens wearers, and they were significantly younger than the non-contact lens wearers (mean age 35 (SD = 1) versus 48 (± 2) years). The mean best corrected visual acuity (BCVA) in the better eye was 1.0 (± 0.1) (decimal acuity). There was no difference in BCVA between contact lens wearers and non-contact lens wearers. The mean Ocular Surface Disease Index (OSDI) score was 22 (± 19), and 138 patients had at least one positive homeostasis marker. Eighty-six had DED, 52 had signs without symptoms, and 23 had symptoms without signs of DED. The sensitivity and specificity of OSDI in detecting any positive homeostasis marker were 62% and 54%, respectively. In all, 106 patients had meibomian gland dysfunction (MGD), of which 49 were asymptomatic. In a ROC analysis, an OSDI ≥ 13 showed a diagnostic ability to differentiate between patients with a fluorescein breakup time (FBUT) < 10 seconds and a fluorescein breakup time ≥ 10 seconds, but not between patients with and without staining or MGD. The majority of patients had dry eye signs and/or dry eye symptoms. Routine assessment of FBUT and meibomian glands may enable case finding of DED in optometric practice.

scholarly journals Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Miyuki Kubota ◽  
Motoko Kawashima ◽  
Sachiko Inoue ◽  
Toshihiro Imada ◽  
Shigeru Nakamura ◽  
...  
Keyword(s):  
Dry Eye ◽  
Molecular Hydrogen ◽  
Human Subjects ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Efficacy Trial ◽  
Tear Secretion ◽  
Eye Symptoms ◽  
New Treatment ◽  
Dry Eye Symptoms

AbstractThe incidence of dry eye disease is increasing worldwide because of the aging population and increasing use of information technology. Dry eye disease manifests as tear-layer instability and inflammation caused by osmotic hypersensitization in tear fluids; however, to our knowledge, no agent that treats both pathologies simultaneously is available. Molecular hydrogen (H2) is known to be effective against various diseases; therefore, we aimed to elucidate the effects of H2on tear dynamics and the treatment of dry eye disease. We revealed that administering a persistent H2-generating supplement increased the human exhaled H2concentration (p < 0.01) and improved tear stability (p < 0.01) and dry eye symptoms (p < 0.05) significantly. Furthermore, H2significantly increased tear secretion in healthy mice (p < 0.05) and significantly suppressed tear reduction in a murine dry eye model (p = 0.007). H2significantly and safely improved tear stability and dry eye symptoms in a small exploratory group of 10 human subjects, a subset of whom reported dry eye symptoms prior to treatment. Furthermore, it increased tear secretion rapidly in normal mice. Therefore, H2may be a safe and effective new treatment for dry eye disease and thus larger trials are warranted.

scholarly journals The Association between Dry Eye Disease and Physical Activity as well as Sedentary Behavior: Results from the Osaka Study

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Motoko Kawashima ◽  
Miki Uchino ◽  
Norihiko Yokoi ◽  
Yuichi Uchino ◽  
Murat Dogru ◽  
...  
Keyword(s):  
Physical Activity ◽  
Sedentary Behavior ◽  
Dry Eye ◽  
Visual Display ◽  
Dry Eye Disease ◽  
Activity Level ◽  
Eye Disease ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Large Groups

Purpose. To assess the association of dry eye disease (DED) with physical activity and sedentary behavior.Methods. The cross-sectional survey conducted included Japanese office workers who use visual display terminals (n=672). DED was assessed according to the Japanese Dry Eye Diagnostic Criteria, and participants were categorized into “definite DED,” “probable DED,” or “non-DED” groups based on the results of DED examinations. Physical activity and sedentary behavior of participants were assessed using the International Physical Activity Questionnaire (IPAQ), and physical activity level was calculated in metabolic equivalent units per week (MET, min/week). Participants were classified as having a high, moderate, or low level of physical activity.Results. Participants with abnormal tear break-up time (BUT) (≤5 s) were involved in sedentary behavior for significantly longer duration than those with normal BUT (P=0.035). Non-DED participants (14.5%) tended to have higher levels of physical activity than definite DED participants (2.5%). Participants with definite DED had significantly lower MET scores than those with non-DED (P=0.025).Conclusions. Our findings suggest that a lower level of physical activity and sedentary behavior are associated with DED; however, longitudinal/intervention studies with large groups of participants are needed to validate these findings.

Dry Eye Disease and Work Productivity Loss in Visual Display Users: The Osaka Study

2014 ◽  
Vol 157 (2) ◽  
pp. 294-300 ◽  
Author(s):  
Miki Uchino ◽  
Yuichi Uchino ◽  
Murat Dogru ◽  
Motoko Kawashima ◽  
Norihiko Yokoi ◽  
...  
Keyword(s):  
Dry Eye ◽  
Productivity Loss ◽  
Work Productivity ◽  
Visual Display ◽  
Dry Eye Disease ◽  
Eye Disease

scholarly journals The Diagnostic Value and Accuracy of Conjunctival Impression Cytology, Dry Eye Symptomatology, and Routine Tear Function Tests in Computer Users

2014 ◽  
Vol 6 (02) ◽  
pp. 102-108 ◽  
Author(s):  
Rahul Bhargava ◽  
Prachi Kumar ◽  
Avinash Kaur ◽  
Manjushri Kumar ◽  
Anurag Mishra
Keyword(s):  
Correlation Analysis ◽  
Dry Eye ◽  
Diagnostic Value ◽  
Computer Users ◽  
Impression Cytology ◽  
Schirmer’S Test ◽  
Conjunctival Impression Cytology ◽  
Eye Symptoms ◽  
The Mean ◽  
Dry Eye Symptoms

ABSTRACT Aims and Objectives: To compare the diagnostic value and accuracy of dry eye scoring system (DESS), conjunctival impression cytology (CIC), tear film breakup time (TBUT), and Schirmer's test in computer users. Methods: A case-control study was done at two referral eye centers. Eyes of 344 computer users were compared to 371 eyes of age and sex matched controls. Dry eye questionnaire (DESS) was administered to both groups and they further underwent measurement of TBUT, Schirmer's, and CIC. Correlation analysis was performed between DESS, CIC, TBUT, and Schirmer's test scores. A Pearson's coefficient of the linear expression (R 2) of 0.5 or more was statistically significant. Results: The mean age in cases (26.05 ± 4.06 years) was comparable to controls (25.67 ± 3.65 years) (P = 0.465). The mean symptom score in computer users was significantly higher as compared to controls ( P < 0.001). Mean TBUT, Schirmer's test values, and goblet cell density were significantly reduced in computer users (P < 0.001). TBUT, Schirmer's, and CIC were abnormal in 48.5%, 29.1%, and 38.4% symptomatic computer users respectively as compared to 8%, 6.7%, and 7.3% symptomatic controls respectively. On correlation analysis, there was a significant (inverse) association of dry eye symptoms (DESS) with TBUT and CIC scores (R 2 > 0.5), in contrast to Schirmer's scores (R 2 < 0.5). Duration of computer usage had a significant effect on dry eye symptoms severity, TBUT, and CIC scores as compared to Schirmer's test. Conclusion: DESS should be used in combination with TBUT and CIC for dry eye evaluation in computer users.

scholarly journals Intense Pulse Laser Therapy and Dry Eye Disease

2021 ◽  
Author(s):  
Sana Niazi ◽  
Farideh Doroodgar
Keyword(s):  
Chronic Disease ◽  
Dry Eye ◽  
Management Strategies ◽  
Tear Film ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Second Phase ◽  
Eye Symptoms ◽  
Periocular Region ◽  
New Treatment

The high and increasing prevalence of Dry Eye Disease (DED) highlights the need for new treatment treatments and more effective management strategies for this chronic disease. After training, lid grooming, and various ocular lubricants, the Tear Film & Ocular Surface Society Dry Eye Workshop II (TFOS DEWS II) Management and Therapy Subcommittee recently proposed Intense Pulsed Light (IPL) as the second phase of therapy. Brief flashes of non-coherent light (400–1,200 nm) are delivered to the skin’s surface using IPL technology. Toyos et al. found in 2005 that rosacea sufferers who were treated with IPL in the periocular region had a significant increase in their dry eye symptoms.

scholarly journals The effect of tamarind seed polysaccharidecontaining eye drop in dry eye syndrome: Results of an interventional, comparative, clinical study

2021 ◽  
Vol 2 (2) ◽  
pp. 71-76
Author(s):  
Naser Nozari ◽  
Shahrokh Ramin
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Dry Eye Disease ◽  
Ocular Surface Disease ◽  
Eye Disease ◽  
Eye Drops ◽  
Artificial Tears ◽  
Mean Values ◽  
The Mean ◽  
Contralateral Eye

Background: The mainstay of dry eye treatment is artificial tear solutions. Contralateral eye comparison of 2 types of artificial tears (Xiloial versus Tearlose) in managing dry eye disease was sought in this study. Methods: This study was a prospective, interventional, contralateral eye comparison of 2 types of artificial tears used for managing dry eye disease. The study participants were categorized into mild (13–22 points), moderate (23–32 points), or severe (33–100 points) ocular surface disease according to the baseline ocular surface disease index (OSDI) questionnaire score. Schirmer I and tear film break-up time (TBUT) tests, as well as detailed slit-lamp examinations, were performed at baseline and at the end of the study. All participants received Xiloial monodose eye drops for the right eye and Tearlose eye drops for the left eye, administered as a single drop 4 times per day. Furthermore, they were instructed to perform lid hygiene every 12 hours per day for both eyes. Results: Thirty-five patients (70 eyes) with a mean ± standard (SD) age of 50.2 ± 13.4 years were included, and 14 (40%) were men. The mean ± SD of the OSDI score was 44.24 ± 22.59 at baseline. Of the 35 patients, 10 (28.6%), 5 (14.3%), and 20 (57.1%) had mild, moderate, and severe ocular surface disease, respectively, according to the baseline OSDI score. Compared to baseline, the mean values of both TBUT and Schirmer I tests improved significantly in both groups (both P < 0.001). In comparing the final mean values between the 2 groups, this improvement was comparable for the Schirmer I test (P = 0.179), but TBUT in Tearlose-instilled eyes improved significantly more than in the fellow eyes (P < 0.001). Conclusions: Both Xiloial and Tearlose eye drops improved tear stability and tear production after a 2 week treatment period in eyes with dry eye disease. This improvement was comparable for tear production, but Tearlose-instilled eyes showed significantly greater improvement in tear stability. Further studies with longer follow-up and larger sample sizes could provide more reliable results as a basis for the clinical use of this TSP-containing lubricant eye drop solution in dry eye disease.

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