scholarly journals Provocation of Dry Eye Disease during COVID-19 Lockdown

2021 ◽  
Author(s):  
Nutnicha Neti ◽  
Pinnita Prabhasawat ◽  
Chareenun Chirapapaisan ◽  
Panotsom Ngowyutagon
Keyword(s):  
Mental Health ◽  
Health Status ◽  
Dry Eye ◽  
Dry Eye Disease ◽  
Mental Health Status ◽  
Eye Disease ◽  
Eye Symptoms ◽  
The Mean ◽  
The Impact ◽  
Dry Eye Symptoms

Abstract To assess the impact of COVID-19 lockdown measures on dry-eye symptoms in a community-based population, a cross-sectional study was conducted during the first wave of the COVID-19 outbreak in Thailand. An online survey was distributed via social media between June and July 2020. The questionnaire elicited information on demographics, dry-eye symptoms, viewing habits, and mental health status. There were 535 respondents. Thirty-seven percent reported having been diagnosed with dry-eye disease (DED). During the lockdown, the mean dry-eye symptom score (DESS) of overall participants dropped significantly from 81.6±15.9 to 79.8±17.4 (P<0.001). The mean, daily, visual display terminal (VDT) usage increased from 10.55±5.16 hours to 13.08±5.65 hours (P<0.001). A negative correlation between age and VDT usage was observed in both the normal and lockdown situations. One-quarter of all participants had an abnormal mental health status. The female gender (OR 1.86; 95% CI 1.14–3.04) and increased VDT usage during the lockdown (OR 5.68; 95% CI 3.49–9.23) were independently associated with worsening dry-eye symptoms. The lockdown measures abruptly altered the behaviors and lifestyles of the overall population. Excessive exposure to VDTs were associated with deteriorated dry-eye symptoms, and it possibly contributed to the increased DED incidence in the general population.

scholarly journals Provocation of dry eye disease symptoms during COVID-19 lockdown

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nutnicha Neti ◽  
Pinnita Prabhasawat ◽  
Chareenun Chirapapaisan ◽  
Panotsom Ngowyutagon
Keyword(s):  
Mental Health ◽  
Health Status ◽  
Dry Eye ◽  
Visual Display ◽  
Dry Eye Disease ◽  
Mental Health Status ◽  
Eye Disease ◽  
Eye Symptoms ◽  
The Mean ◽  
Dry Eye Symptoms

AbstractTo assess the impact of COVID-19 lockdown measures on dry-eye symptoms in a community-based population, a cross-sectional study was conducted during the first wave of the COVID-19 outbreak in Thailand. An online survey was distributed via social media between June and July 2020. The questionnaire elicited information on demographics, dry-eye symptoms, use of visual display terminals, and mental health status. There were 535 respondents. Thirty-seven percent reported having been diagnosed with dry-eye disease (DED). During the lockdown, the mean dry-eye symptom score (DESS) of overall participants dropped significantly from 81.6 ± 15.9 to 79.8 ± 17.4 (P < 0.001). The mean, daily, visual display terminal (VDT) usage increased from 10.55 ± 5.16 to 13.08 ± 5.65 h (P < 0.001). A negative correlation between age and VDT usage was observed in both the normal and lockdown situations. One-quarter of all participants had an abnormal mental health status. The female gender (OR 1.86; 95% CI 1.14–3.04) and increased VDT usage during the lockdown (OR 5.68; 95% CI 3.49–9.23) were independently associated with worsening dry-eye symptoms. The lockdown measures abruptly altered the behaviors and lifestyles of the overall population. Excessive exposure to VDTs were associated with deteriorated dry-eye symptoms, and it possibly contributed to the increased DED incidence in the surveyed population.

scholarly journals Mental Health Status in Dry Eye Disease – a Case Control Study

2018 ◽  
Vol 12 (1) ◽  
pp. 56 ◽  
Author(s):  
Luxmi Singh ◽  
Vijay Pratap Singh ◽  
Swati Yadav ◽  
Pragati Garg ◽  
◽  
...  
Keyword(s):  
Mental Health ◽  
Health Status ◽  
Dry Eye ◽  
Case Control Study ◽  
Case Control ◽  
Dry Eye Disease ◽  
Mental Health Status ◽  
Eye Disease ◽  
Control Study

scholarly journals Impact of Prolonged Face Mask Wearing On Tear Break-Up Time and Dry Eye Symptoms in Health Care Professionals

2021 ◽  
Author(s):  
Mine Esen Baris ◽  
Suzan Guven Yilmaz ◽  
Melis Palamar
Keyword(s):  
Health Care ◽  
Dry Eye ◽  
Health Care Professionals ◽  
Face Mask ◽  
Ophthalmological Examination ◽  
Eye Symptoms ◽  
The Mean ◽  
Break Up ◽  
The Impact ◽  
Dry Eye Symptoms

Abstract Purpose To evaluate the impact of prolonged surgical face mask wearing on dry eye symptoms and tear film break-up time (T-BUT) in health care professionals. Materials and Methods A total of 33 health care professionals were included in this cross sectional, prospective study. T-BUT measurements were performed twice for all participants in the morning (8 am) and in the afternoon (5 pm) in addition to a complete ophthalmological examination. The subjects also filled-in the ocular surface disease index (OSDI) questionnaire twice, before and after wearing the face mask, on the same day. Results Sixty six eyes of 33 participants (17 female and 16 male) were evaluated. The mean age was 33.6 ± 7.55 (24–48) years and mean total duration with mask on between the two evaluations was 514 ± 12.5 (495–526) minutes. The mean T-BUT was 9.3 ± 1.0 (3–16) seconds at 8 am and 8.3 ± 1.5 (3–14) seconds at 5 pm (p = 0.01). The mean OSDI score was 20.1 ± 8.3 (0-68.75) at 8 am and 27.4 ± 10.4 (0-81.25) at 5 pm (p < 0.01). Conclusion Use of a surgical mask for the entire work day was seen to worsen T-BUT and dry eye symptoms in healthy individuals. Ophthalmologists should be aware of possible worsening of condition in patients with dry eye with the prolonged use of face masks and consider modifications if necessary.

Dry eye disease, dry eye symptoms and depression: the Beijing Eye Study

2013 ◽  
Vol 97 (11) ◽  
pp. 1399-1403 ◽  
Author(s):  
Antoine Labbé ◽  
Ya Xing Wang ◽  
Ying Jie ◽  
Christophe Baudouin ◽  
Jost B Jonas ◽  
...  
Keyword(s):  
Dry Eye ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Beijing Eye Study ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

scholarly journals Case finding of dry eye disease in Norwegian optometric practice: a cross-sectional study

2021 ◽  
Vol 14 (1) ◽  
pp. 1-6
Author(s):  
Ann Elisabeth Ystenæs ◽  
Ingeborg Sand ◽  
Vibeke Sundling
Keyword(s):  
Dry Eye ◽  
Contact Lens ◽  
Cross Sectional Study ◽  
Case Finding ◽  
Eye Disease ◽  
Cross Sectional ◽  
Eye Symptoms ◽  
The Mean ◽  
Breakup Time ◽  
Dry Eye Symptoms

Optometrists are primary eye care providers, and it is essential that they efficiently identify patients who will benefit from dry eye management. The aim of the study was to explore case finding of dry eye disease (DED) in optometric practice. A cross-sectional study examining dry eye symptoms and signs in 186 patients (18–70 years of age) attending a routine eye examination, with DED defined according to the criteria of the Tear Film and Ocular Surface Society Dry Eye Workshop II. Standard statistical tests were used, and clinical diagnostics were explored using sensitivity, specificity, and receiveroperating curve (ROC) statistics. Fifty-six patients were contact lens wearers, and they were significantly younger than the non-contact lens wearers (mean age 35 (SD = 1) versus 48 (± 2) years). The mean best corrected visual acuity (BCVA) in the better eye was 1.0 (± 0.1) (decimal acuity). There was no difference in BCVA between contact lens wearers and non-contact lens wearers. The mean Ocular Surface Disease Index (OSDI) score was 22 (± 19), and 138 patients had at least one positive homeostasis marker. Eighty-six had DED, 52 had signs without symptoms, and 23 had symptoms without signs of DED. The sensitivity and specificity of OSDI in detecting any positive homeostasis marker were 62% and 54%, respectively. In all, 106 patients had meibomian gland dysfunction (MGD), of which 49 were asymptomatic. In a ROC analysis, an OSDI ≥ 13 showed a diagnostic ability to differentiate between patients with a fluorescein breakup time (FBUT) < 10 seconds and a fluorescein breakup time ≥ 10 seconds, but not between patients with and without staining or MGD. The majority of patients had dry eye signs and/or dry eye symptoms. Routine assessment of FBUT and meibomian glands may enable case finding of DED in optometric practice.

The Impact of Addiction on Family Members Mental Health Status

2019 ◽  
Vol 11 (2) ◽  
pp. 129-134
Author(s):  
Farshid Shamsaei ◽  
Mohammad Baanavi ◽  
Zahra Marzieh Hassanian ◽  
Fatemeh Cheraghi
Keyword(s):  
Mental Health ◽  
Substance Abuse ◽  
Health Status ◽  
Substance Abusers ◽  
Family Members ◽  
Psychological Needs ◽  
Mental Health Status ◽  
Control Group ◽  
The Mean ◽  
The Impact

Background: Effects of substance abuse frequently expand beyond the nuclear family. Extended family members can experience feelings of abandonment, anxiety, fear, anger, concern, embarrassment, or guilt. Thus, they may wish to ignore or cut ties with the person involved in substance abuse. The aim of this study was to compare the mental health status of families with and without substance abusers. Methods: This cross sectional study was conducted among 114 family members with substance abusers (case group) and 114 without substance abusers (control group) in Hamadan city of Iran, in a time period from October to December 2016. Data collection tools included demographic and SCL-90-R questionnaires. Data were analyzed by t- test using SPSS software version 16. The significance level was considered less than 0.05. Results: The mean age of participants in the case and control groups was 33±4.7 and 35±5.2 years. There was a significant difference in the mean of subscales which included somatization, interpersonal sensitivity, depression, anxiety and phobia in families with and without substance abusers (p< 0.001). In other words, the mental health status of family members with a substance abuser was lower than in the control group. Overall, 29.4% of family members with substance abusers and 16% without substance abusers were suspected to have mental disorders. Conclusion: Substance abuse is a disorder that can impact families in countless ways. Therefore, it is recommended that more attention should be given to this group toward planning mental health programs. Also, families should be screened by health professionals in regard to psychological needs and improvement of their mental health conditions.

scholarly journals Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Miyuki Kubota ◽  
Motoko Kawashima ◽  
Sachiko Inoue ◽  
Toshihiro Imada ◽  
Shigeru Nakamura ◽  
...  
Keyword(s):  
Dry Eye ◽  
Molecular Hydrogen ◽  
Human Subjects ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Efficacy Trial ◽  
Tear Secretion ◽  
Eye Symptoms ◽  
New Treatment ◽  
Dry Eye Symptoms

AbstractThe incidence of dry eye disease is increasing worldwide because of the aging population and increasing use of information technology. Dry eye disease manifests as tear-layer instability and inflammation caused by osmotic hypersensitization in tear fluids; however, to our knowledge, no agent that treats both pathologies simultaneously is available. Molecular hydrogen (H2) is known to be effective against various diseases; therefore, we aimed to elucidate the effects of H2on tear dynamics and the treatment of dry eye disease. We revealed that administering a persistent H2-generating supplement increased the human exhaled H2concentration (p < 0.01) and improved tear stability (p < 0.01) and dry eye symptoms (p < 0.05) significantly. Furthermore, H2significantly increased tear secretion in healthy mice (p < 0.05) and significantly suppressed tear reduction in a murine dry eye model (p = 0.007). H2significantly and safely improved tear stability and dry eye symptoms in a small exploratory group of 10 human subjects, a subset of whom reported dry eye symptoms prior to treatment. Furthermore, it increased tear secretion rapidly in normal mice. Therefore, H2may be a safe and effective new treatment for dry eye disease and thus larger trials are warranted.

scholarly journals Dexamethasone-Loaded Nanostructured Lipid Carriers for the Treatment of Dry Eye Disease

Pharmaceutics ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 905
Author(s):  
Sangeeta Kumari ◽  
Madhuri Dandamudi ◽  
Sweta Rani ◽  
Elke Behaeghel ◽  
Gautam Behl ◽  
...  
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Pilot Scale ◽  
Dry Eye Disease ◽  
Rapid Screening ◽  
Eye Disease ◽  
Topical Steroids ◽  
Nanostructured Lipid Carrier ◽  
The Impact ◽  
Ophthalmic Formulation

Dry eye disease (DED) or keratoconjunctivitis sicca is a chronic multifactorial disorder of the ocular surface caused by tear film dysfunction. Symptoms include dryness, irritation, discomfort and visual disturbance, and standard treatment includes the use of lubricants and topical steroids. Secondary inflammation plays a prominent role in the development and propagation of this debilitating condition. To address this we have investigated the pilot scale development of an innovative drug delivery system using a dexamethasone-encapsulated cholesterol-Labrafac™ lipophile nanostructured lipid carrier (NLC)-based ophthalmic formulation, which could be developed as an eye drop to treat DED and any associated acute exacerbations. After rapid screening of a range of laboratory scale pre-formulations, the chosen formulation was prepared at pilot scale with a particle size of 19.51 ± 0.5 nm, an encapsulation efficiency of 99.6 ± 0.5%, a PDI of 0.08, and an extended stability of 6 months at 4 °C. This potential ophthalmic formulation was observed to have high tolerability and internalization capacity for human corneal epithelial cells, with similar behavior demonstrated on ex vivo porcine cornea studies, suggesting suitable distribution on the ocular surface. Further, ELISA was used to study the impact of the pilot scale formulation on a range of inflammatory biomarkers. The most successful dexamethasone-loaded NLC showed a 5-fold reduction of TNF-α production over dexamethasone solution alone, with comparable results for MMP-9 and IL-6. The ease of formulation, scalability, performance and biomarker assays suggest that this NLC formulation could be a viable option for the topical treatment of DED.

scholarly journals The Diagnostic Value and Accuracy of Conjunctival Impression Cytology, Dry Eye Symptomatology, and Routine Tear Function Tests in Computer Users

2014 ◽  
Vol 6 (02) ◽  
pp. 102-108 ◽  
Author(s):  
Rahul Bhargava ◽  
Prachi Kumar ◽  
Avinash Kaur ◽  
Manjushri Kumar ◽  
Anurag Mishra
Keyword(s):  
Correlation Analysis ◽  
Dry Eye ◽  
Diagnostic Value ◽  
Computer Users ◽  
Impression Cytology ◽  
Schirmer’S Test ◽  
Conjunctival Impression Cytology ◽  
Eye Symptoms ◽  
The Mean ◽  
Dry Eye Symptoms

ABSTRACT Aims and Objectives: To compare the diagnostic value and accuracy of dry eye scoring system (DESS), conjunctival impression cytology (CIC), tear film breakup time (TBUT), and Schirmer's test in computer users. Methods: A case-control study was done at two referral eye centers. Eyes of 344 computer users were compared to 371 eyes of age and sex matched controls. Dry eye questionnaire (DESS) was administered to both groups and they further underwent measurement of TBUT, Schirmer's, and CIC. Correlation analysis was performed between DESS, CIC, TBUT, and Schirmer's test scores. A Pearson's coefficient of the linear expression (R 2) of 0.5 or more was statistically significant. Results: The mean age in cases (26.05 ± 4.06 years) was comparable to controls (25.67 ± 3.65 years) (P = 0.465). The mean symptom score in computer users was significantly higher as compared to controls ( P < 0.001). Mean TBUT, Schirmer's test values, and goblet cell density were significantly reduced in computer users (P < 0.001). TBUT, Schirmer's, and CIC were abnormal in 48.5%, 29.1%, and 38.4% symptomatic computer users respectively as compared to 8%, 6.7%, and 7.3% symptomatic controls respectively. On correlation analysis, there was a significant (inverse) association of dry eye symptoms (DESS) with TBUT and CIC scores (R 2 > 0.5), in contrast to Schirmer's scores (R 2 < 0.5). Duration of computer usage had a significant effect on dry eye symptoms severity, TBUT, and CIC scores as compared to Schirmer's test. Conclusion: DESS should be used in combination with TBUT and CIC for dry eye evaluation in computer users.

scholarly journals An assessment of mental health status of physicians working in medical college hospitals of Dhaka city

2020 ◽  
Vol 32 (2) ◽  
pp. 37-39
Author(s):  
Kazi Mahbubul Haque ◽  
Md Shafiqul Islam ◽  
Saida Sharmin
Keyword(s):  
Mental Health ◽  
Mental Illness ◽  
Health Status ◽  
Health Care Professionals ◽  
Cross Sectional Study ◽  
Mental Health Status ◽  
Dhaka City ◽  
Cross Sectional ◽  
Medical College ◽  
The Impact

Mental health status is often ignored in our country. Even many health care professionals commonly ignore the impact of mental illness on both daily and professional lives, which may lead to dire consequences. The purpose of this study was to find the mental health status of physicians working in medical college hospitals of Dhaka city. A cross sectional study was conducted from January to December 2015 for this purpose among 215 number of respondents selected conveniently. Data were collected from 210 physicians by face-to face interview using a semi structured questionnaire containing 4DSQ (Four-Dimensional Symptom Questionnaire), socio economic and other variables. The prevalence of mental illness was calculated according to the scoring system of the scale. Mental illness prevalence was as follows: distress 20%, Anxiety 15.7%, Depression 15.2% and Somatization 8.6%. Majority of the respondents were interns and below 30 years of age. However, in light of current pandemic situation, regular assessment of health personnel’s mental health is needed more than ever. Bang J Psychiatry 2018;32(2): 37-39

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