scholarly journals A retrospective clinical analysis of pediatric paragonimiasis in a Chinese children’s hospital from 2011 to 2019

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Manning Qian ◽  
Fei Li ◽  
Yuhan Zhang ◽  
Zhongwei Qiao ◽  
Yingyan Shi ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Clinical Analysis ◽  
High Rate ◽  
Serological Tests ◽  
Female Ratio ◽  
Children's Hospital ◽  
Male Female Ratio ◽  
Children’S Hospital ◽  
History Of ◽  
Rate Of Failure

AbstractDiagnosis of pediatric paragonimiasis is difficult because of its non-specific clinical manifestations. We retrospectively reviewed the records of pediatric paragonimiasis in Children’s Hospital of Fudan University from January 2011 to May 2019. The confirmed diagnosis of paragonimiasis was based on positive anti-parasite serological tests from the local Center for Disease Control (CDC). A total of 11 patients (mean age: 7.7 ± 3.1, male–female ratio: 7:4) diagnosed as paragonimiasis were included. 81.8% were from endemic areas such as Sichuan and Yunnan, and 36% had a clear history of raw crab or crayfish consumption. The characteristic clinical features of pediatric paragonimiasis were eosinophilia (100%), pleural effusion (81.8%), hepatomegaly (54.5%), ascites (54.5%), and subcutaneous nodules (45.5%). Misdiagnosed with other diseases including tuberculosis (18.2%), pneumonia (9.1%), intracranial space-occupying lesions (9.1%) and brain abcess (9.1%) led to rehospitalization and prolonged hospitalization. For treatment, a 3-day course of 150 mg/kg praziquantel (PZQ) didn’t show ideal treatment effectivity and 63.6% needed more than one course of PZQ, while triclabendazole in a total dose of 10 mg/kg had a better efficacy to stubborn manifestations. This study indicated that pediatric paragonimiasis was often misdiagnosed, and the treatment with a 3-day course of 150 mg/kg PZQ had a high rate of failure.

scholarly journals Screening household members of shepherds in brucellosis endemic areas in China and reporting follow-up results of asymptomatic infections

2020 ◽  
Author(s):  
Jing Hu ◽  
Huixin Yang ◽  
Xiangyi Zhang ◽  
Siwen Zhang ◽  
Taijun Wang ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Asymptomatic Infection ◽  
Female Ratio ◽  
Brucella Infection ◽  
Male Female Ratio ◽  
History Of ◽  
Household Members ◽  
Asymptomatic Infections ◽  
Endemic Areas

Abstract Background: Brucellosis is a zoonotic infectious disease caused by brucella, patients often show obvious clinical manifestation, however, many cases of asymptomatic brucella infection were reported. Previous scholars have described or screened the asymptomatic infection, but little attention has been paid to the results. This research focused on the short-term results in patients with asymptomatic brucella infectionMethods: 595 household members of shepherds in brucellosis endemic areas were included, all of them have questionnaires and laboratory tests. Based on inclusion and exclusion criteria for the cohort, 15 asymptomatic infections were included and followed-up for 18months.Results: Among 595 subjects, 34(5.7%) were asymptomatic infections, 460(77.3%) were healthy, 58patients (9.7%) were diagnosed as brucellosis, 13(2.2%) suspected cases, 19(3.2%) cured cases and 11(1.8%) unclear diagnosis. Among 15 asymptomatic infections, the median age was 34 [12, 50] years, there were 40%cases <18 years old and the male-female ratio was 1.5:1, 60% cases were farmers and herdsmen, 11(73.3%) cases had a history of possible exposure to brucella. Average follow-up time was 10.47 ± 8.47 months. A total of 7 asymptomatic infections developed into brucellosis, of which five patients turned in the first month of follow-up, one patient in the second month, and one minor case turned in the seventh month. Remaining asymptomatic infections showed negative outcomes after 7 months of follow-up, among them, SAT titer decreased in two cases, no changes in SAT titer and clinical manifestations in six cases.Conclusions: Continued exposure to brucella may be a major risk factor for asymptomatic infection turn to brucellosis.

scholarly journals Current Situation of Treatment and Follow-up Re-examination of Children with Epilepsy at Vietnam National Children’s Hospital

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Thi Huyen Tran ◽  
Vu Hung Cao ◽  
Van Hoc Tran ◽  
Danh Ngon Nguyen
Keyword(s):  
Treatment Time ◽  
Age Of Onset ◽  
Treatment Compliance ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Female Ratio ◽  
Children's Hospital ◽  
Male Female Ratio ◽  
Children’S Hospital

Purpose: To assess treatment compliance and follow-up appointment of children with epilepsy at the Vietnam National Children’s Hospital in 2019. Method: A cross-sectional descriptive study was conducted on pediatric patients and primary caregivers came for examination and treatment at the Neurology Department, Vietnam National Children’s Hospital from January 2019 to December 2019. Results: Mean age was 74.3 ± 45.1 (month age). The most common age group was the 2-6 year old group (40.5%), the lower rate was the 6-12 year old group (30.0%), and rest groups was the low rate. The male: female ratio is 1.43:1. Most of the main caregivers are parents (92.5%). Average treatment time was 20.4 ± 15.7 months, the rate of good adherence to treatment 43.5%, 31.5% of children had  moderated adhering to treatment and 25.0% had poor adhering to treatment. Within 6 months, 40.5% of children re-examined on time. The reasons for not complying with on-time re-examination were mainly due to the caregiver's busy work or the child was busy at school (37.8%) and the distance from home to hospital (26.1%). Conclusions: The percentage of patients who complied with treatment and re-examination was not high. Factors that were statistically significant for children's non-compliance were: health insurance level, age of onset, duration of treatment, and frequency of attacks following treatment.

scholarly journals Wheat Pill Poisoning: Management and outcome in cases reported in DG Khan District.

2021 ◽  
Vol 28 (08) ◽  
pp. 1096-1100
Author(s):  
Alina Nawaz Khan ◽  
◽  
Rabia Khan ◽  
Naheed Siddiqui ◽  
Salman Pervaiz Rana ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Coconut Oil ◽  
Symptomatic Treatment ◽  
Aluminum Phosphide ◽  
Female Ratio ◽  
Male Female Ratio ◽  
History Of ◽  
Recovery Result ◽  
Study Setting ◽  
Overall Mortality

Objective: To determine the clinical manifestations and prognosis of victims presenting with wheat pill poisoning. Study Design: Prospective Cohort Study. Setting: Emergency Department in District Headquarter Hospital DG Khan. Period: February 2019 to January 2020. Material & Methods: Patients admitted with history of accidental or suicidal wheat pills poisoning were followed over a period of 3 to 6 months. Symptomatic treatment was initially given for 2-3 hours. The patients were retained in CCU for 24 hours before shifting to ward. Research tool (proforma) was designed for collection and interpretation of data. Acute Physiology and Chronic Health Evaluation Score 2 (APACHE-2) score was used for prognosis and recovery. Result: Out of 96 victims of aluminum phosphide ingestion male/female ratio was 2:1, 64% (n= 64) were females and 36% (n=32) were males. Higher incidence was found in age group (16–25 years (n= 27 victims). Overall mortality was 63 (65.6%). Conclusion: Wheat pill was a poison of choice among teens and adults in Pakistan as it is freely available and cheap. Arrhythmia and metabolic acidosis are the major causes of death after wheat pills ingestion. Coconut oil was found effective in delaying the absorption.

Clinical and paraclinical characteristics of Chlamydia trachomatis pneumonia in infants less than 6 months of age at National Children’s Hospital

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Hien Pham Thu
Keyword(s):  
Chlamydia Trachomatis ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Children's Hospital ◽  
Persistent Cough ◽  
Children’S Hospital ◽  
History Of ◽  
Eosinophil Counts

SUMMARY Objectives: The study aim was to describe clinical and paraclinical characteristics of Chlamydia trachomatis pneumonia in children under 6 months of age at National Children’s Hospital. Methods: This cross-sectional study included 71 cases of C. trachomatis pneumonia in Respiratory Department, National Children’s Hospital between 1 September 2017 and 31 August 2018. Results: Important features of C. trachomatis pneumonia in children under 6 months of age include persistent cough, nasopharyngitis, conjunctivitis, history of vaginal birth, mother’s history of vaginosis during pregnancy. Absolute eosinophil counts greater than 300/mm3 may suggest C. trachomatis pneumonia. Conclusion: Clinical manifestations of pneumonia due to C. trachomatis pneumonia are persistent cough, nasopharyngitis, conjunctivitis, mother’s history of vaginosis during pregnancy. A higher than 300 eosinophils/mm3 is strongly associated with C. trachomatis pneumonia.

Clinical characteristics and treatment results of Shigella in Digestion department, National Children’s Hospital 2019

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Hà Ngọc Đạt
Keyword(s):  
Clinical Characteristics ◽  
High Fever ◽  
Treatment Results ◽  
Cross Sectional ◽  
Female Ratio ◽  
Children's Hospital ◽  
Male Female Ratio ◽  
Hospital Patients ◽  
Children’S Hospital ◽  
Epidemiological Characteristics

Objectives: 1. Describe some clinical epidemiological characteristics of Shigella dysentery in children in the Department of Gastroenterology of Central Children's Hospital in 2019; 2. Comment on treatment results in the above patients. Subjects: All patients under 15 years old are admitted to the Hospital of Gastroenterology, Vietnam National Children's Hospital.. Method of cross-sectional description. Results: More morbidity rates in men than in women. The male / female ratio is 1.8 / 1. In which, the highest incidence is from 1 to 3 years old. In comparison with other seasons, autumn has the highest proportion of hospital patients, accounting for 46.4%. The majority of patients admitted to hospital due to diarrhea and fever accompanied by blood in the stool accounted for 41.3%, some came to the hospital due to high fever with 15/184 patients accounting for 7.9%, high fever. Accompanied by seizures, accounting for 16.5%. The rate of treatment with Ciprofloxacin is 89.5%. The recovery rate is quite high, 93.3%, the percentage of patients who are also significantly better at 6.7% and there is no case of treatment failure.  

Etiology and clinical features of epididymo-orchitis: A single-center study in Tehran, Iran

2020 ◽  
Vol 20 ◽  
Author(s):  
Sara Abolghasemi ◽  
Mohammad Alizadeh ◽  
Ali Hashemi ◽  
Shabnam Tehrani
Keyword(s):  
Chlamydia Trachomatis ◽  
Clinical Symptoms ◽  
Urine Culture ◽  
Clinical Manifestations ◽  
Urinary Frequency ◽  
Serological Tests ◽  
Duration Of Symptoms ◽  
Two Samples ◽  
History Of ◽  
Tract Infections

Introduction: Epididymo-orchitis is a common urological disease among men. Little is known about the clinical and epidemiological aspects of the disease in Iran. Thus, the present study was aimed to investigate the etiology, clinical sequelae and risk factors of patients with epididymo-orchitis in Tehran, Iran. Materials and Methods: Patients presenting with epididymo-orchitis were prospectively analyzed in order to study the etiology and pattern of the disease. Bacteriological, molecular and serological tests were undertaken to look for Chlamydia trachomatis, Neisseria gonorrhoeae, Brucella spp., Mycoplasma spp, and other bacteria. Results: Fifty patients with epididymo-orchitis were evaluated according to their clinical symptoms, duration of symptoms, physical examination, and laboratory studies. The mean age of the patients was 53 years. Fever, dysuria, pain in the flanks, urinary frequency and discharges occurred in 58.0%, 50.0%, 50.0%, 28.0% and 6.0%, respectively. Bacterial pathogen was identified in 26% (13/50) of patients by urine culture. Escherichia coli was the etiological agent in 11/13 patients (84.6%). Two out of 50 patients (4.0%) were also positive for Chlamydia trachomatis. Two samples were serologically positive for Brucella spp. High Mean age, fever, urinary frequency, history of the underlying disease and history of urinary tract infections were found to have a significant association with the positive bacteriologic urine culture (P<0.05). Conclusions: The most common clinical manifestations were fever, dysuria, and abdominal pain. E. coli and C. trachomatis were the major causative agents. Use of a set of diagnostic approaches including clinical symptoms, urine culture and more precise techniques such as PCR should be taken into consideration for the definitive diagnosis.

scholarly journals Author Correction: A retrospective clinical analysis of pediatric paragonimiasis in a Chinese children’s hospital from 2011 to 2019

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Manning Qian ◽  
Fei Li ◽  
Yuhan Zhang ◽  
Zhongwei Qiao ◽  
Yingyan Shi ◽  
...  
Keyword(s):  
Clinical Analysis ◽  
Children's Hospital ◽  
Children’S Hospital

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals Hospital based study of demography and clinical picture of vernal keratoconjunctivitis

2017 ◽  
Vol 6 (1) ◽  
pp. 65 ◽  
Author(s):  
Maneesha Sethi ◽  
Ridham Nanda ◽  
Amarjeet Singh Bali ◽  
P. Sadhotra
Keyword(s):  
Mixed Type ◽  
Clinical Presentation ◽  
Signs And Symptoms ◽  
Vernal Keratoconjunctivitis ◽  
Female Ratio ◽  
Northern India ◽  
Department Of Ophthalmology ◽  
Male Female Ratio ◽  
History Of ◽  
Ocular Morbidity

Background: Vernal Keratoconjunctivitis (VKC) is common cause of ocular morbidity in children living in tropical countries. Its diagnosis is based on signs and symptoms of the disease. The study was undertaken to stress upon the demography and clinical presentation of VKC.Methods: Retrospective pre-formed proforma of 155 patients of VKC, who were detected at random in the out - patient department of ophthalmology, ASCOMS, Jammu from May 2016 to April 2017, were analyzed.Results: Mean age at presentation was 10.31 years +4.05. The Male: Female ratio was 4.96:1. Majority of patients reported in the month of May. Mixed type of VKC was predominant. Personal or family history of allergy was seen in 5.8% of patients. Itching (100%) was commonest symptom and palpaberal papillae were commonest sign seen in 78.70% of patients.Conclusions: Clinical pattern of VKC seen in hot and dry climate of Northern India is like that seen in other parts of country.

Clinical Manifestations of Cholelithiasis in Quito, Ecuador. A Cohort Study

2021 ◽  
pp. 12
Author(s):  
◽  
◽  
Keyword(s):  
Epigastric Pain ◽  
Medical Center ◽  
Clinical Manifestations ◽  
Abdominal Ultrasound ◽  
Common Symptom ◽  
Low Back ◽  
Female Ratio ◽  
Male Female Ratio ◽  
The Right ◽  
A Prospective Study

Introduction: A prospective study was carried out, with the aim of establishing the clinical manifestations of cholelithiasis in the population of Quito, Ecuador. Methods: During the period from January 2012 to October 2017, 534 patients were referred from different outpatient clinics of the Ecuadorian Institute of Social Security to the Batan Medical Center with the diagnosis of cholelithiasis after a clinical assessment and abdominal ultrasound, to be treated surgically. Results: Sixty-nine percent of patients were female with a male-female ratio of 1:2.21. Mean age was 44.9 years. Pain was the most common symptom in our study: 95.7%. Among these patients, pain was located in the epigastrium in 49.8%, in the right hypochondrium in 45.1% and only 0.8% had low back pain. Pain ranged from moderate and even severe. The remaining 4.3% of patients had dyspepsia or were asymptomatic. Conclusions: This finding highlights the fact that epigastric pain must be always considered as a clinical manifestation on cholelithiasis.

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