scholarly journals Automatic 3D dense phenotyping provides reliable and accurate shape quantification of the human mandible

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pieter-Jan Verhelst ◽  
H. Matthews ◽  
L. Verstraete ◽  
F. Van der Cruyssen ◽  
D. Mulier ◽  
...  

AbstractAutomatic craniomaxillofacial (CMF) three dimensional (3D) dense phenotyping promises quantification of the complete CMF shape compared to the limiting use of sparse landmarks in classical phenotyping. This study assesses the accuracy and reliability of this new approach on the human mandible. Classic and automatic phenotyping techniques were applied on 30 unaltered and 20 operated human mandibles. Seven observers indicated 26 anatomical landmarks on each mandible three times. All mandibles were subjected to three rounds of automatic phenotyping using Meshmonk. The toolbox performed non-rigid surface registration of a template mandibular mesh consisting of 17,415 quasi landmarks on each target mandible and the quasi landmarks corresponding to the 26 anatomical locations of interest were identified. Repeated-measures reliability was assessed using root mean square (RMS) distances of repeated landmark indications to their centroid. Automatic phenotyping showed very low RMS distances confirming excellent repeated-measures reliability. The average Euclidean distance between manual and corresponding automatic landmarks was 1.40 mm for the unaltered and 1.76 mm for the operated sample. Centroid sizes from the automatic and manual shape configurations were highly similar with intraclass correlation coefficients (ICC) of > 0.99. Reproducibility coefficients for centroid size were < 2 mm, accounting for < 1% of the total variability of the centroid size of the mandibles in this sample. ICC’s for the multivariate set of 325 interlandmark distances were all > 0.90 indicating again high similarity between shapes quantified by classic or automatic phenotyping. Combined, these findings established high accuracy and repeated-measures reliability of the automatic approach. 3D dense CMF phenotyping of the human mandible using the Meshmonk toolbox introduces a novel improvement in quantifying CMF shape.

2019 ◽  
Vol 90 (1) ◽  
pp. 92-99 ◽  
Author(s):  
Maria Eduarda Assad Duarte ◽  
Bruno Frazão Gribel ◽  
Alice Spitz ◽  
Flavia Artese ◽  
José Augusto Mendes Miguel

ABSTRACT Objective To evaluate the reproducibility of digital tray transfer fit on digital indirect bonding by analyzing the differences in bracket positions. Materials and Methods Digital indirect bonding was performed by positioning brackets on digital models superimposed by tomography using Ortho Analyzer (3Shape) software. Thirty-three orthodontists performed indirect bonding on prototyped models of the same malocclusion using prototyped transfer trays for two types of brackets (MiniSprint Roth and BioQuick self-ligating). The models with brackets were scanned using an intraoral scanner (Trios, 3Shape). Superimpositions were made between the digital models obtained after indirect bonding and those from the original virtual setup. To analyze the differences in bracket positions, three planes were examined for each bracket: vertical, horizontal, and angulation. Three orthodontists repeated indirect bonding after 15 days, and Bland-Altman plots and intraclass correlation coefficients were used to evaluate inter- and intraevaluator reproducibility and reliability, respectively. Repeated-measures analysis of variance (ANOVA) was used to analyze the differences between bracket positions, and multivariate ANOVA was used to evaluate the influence of orthodontists' experience on the results. Results Differences between bracket positions were not statistically significant, except mesial-distal discrepancies in the BioQuick group (P = .016). However, differences were not clinically significant (horizontal varied from 0.04 to 0.13 mm; angulation, 0.45° to 2.03°). There was no significant influence of orthodontist experience and years of clinical practice on bracket positions (P = .314 and P = .158). The reproducibility among orthodontists was confirmed. Conclusions The reproducibility of digital indirect bonding was confirmed in terms of bracket positions using three-dimensional printed transfer trays.


Author(s):  
Richard R. Suminski ◽  
Gregory M. Dominick ◽  
Matthew Saponaro

Evidence suggests that video captured with a wearable video device (WVD) may augment or supplant traditional methods for assessing park use. Unmanned aerial systems (UASs) are used to assess human activity, but research employing them for park assessments is sparse. Therefore, this study compared park user counts between a WVD and UAS. A diverse set of 33 amenities (e.g., playground) in three parks were videoed simultaneously by one researcher wearing a WVD and another operating the UAS. Assessments were done at 12 p.m. and 7 p.m. on weekends, with one park evaluated on two occasions 7 days apart. Two investigators independently reviewed videos and reached consensus on the counts of individuals at each amenity. Intraclass correlation coefficients (ICCs) were used to determine intra- and interrater reliabilities. A total of 404 (M = 4.7; SD = 9.6) and 389 (M = 4.5; SD = 9.0) individuals were counted in the UAS and WVD videos, respectively. Absolute agreement was 86% (74/86) and 100% when no individuals were using the amenity. Whether using all 86 videos or only videos having people (48 videos), ICCs indicated excellent reliability (ICC = .99; p < .001). The totals seen for the repeated measures were UAS = 146 and WVD = 136 for Day 1 and UAS = 169 and WVD = 161 for Day 2. Intrarater reliability was excellent for the UAS (ICC = .92; p < .001) and good for the WVD (ICC = .89; p < .001). Disagreement was mainly due to obstructions—people behind or under structures. This study provides support for the use of UASs for counting park users and future research examining the potential benefits of video analysis for assessing park use.


2019 ◽  
Vol 90 (3) ◽  
pp. 397-404 ◽  
Author(s):  
Zhuoxing Xiao ◽  
Zijin Liu ◽  
Yan Gu

ABSTRACT Objective To evaluate three-dimensional (3D) accuracy and reliability of nonradiographic dentofacial images integrated with a two-step method. Methods 3D facial images, cone-beam computed tomography (CBCT) images and digital maxillary dental casts were obtained from 20 pre-orthodontic subjects. Digital dental casts were integrated into 3D facial images using a two-step method based on the anterior tooth area. 3D coordinate values of five dental landmarks were identified in both dentofacial images and CBCT images. The accuracy of the integration method was assessed with paired t-tests between dentofacial images and CBCT-based reference standards. Intraclass correlation coefficients (ICCs) were assessed for the reliability of dentofacial images and CBCT-based images. Analysis of variance and Kruskal-Wallis tests evaluated the accuracy of the method in different dimensions. Results There was no statistical difference between dentofacial images and CBCT reference standards in both translational and rotational dimensions (P &gt; .05). Translational mean absolute errors for full dentitions were within 0.42 mm and ICCs were over 0.998 in x, y, and z directions. Rotational mean absolute errors for full dentitions were within 0.92° and ICCs over 0.734 in pitch, yaw, and roll orientations. Integration errors were significantly greater in the first molar, z-translation, and pitch rotation (P &lt; .05). Conclusions Integrating 3D dentofacial images with the two-step method is precise and acceptable for clinical diagnostics and scientific purposes. Errors were greater in the molar region, z-translation, and pitch rotation.


2012 ◽  
Vol 102 (2) ◽  
pp. 130-138 ◽  
Author(s):  
Jeanna M. Fascione ◽  
Ryan T. Crews ◽  
James S. Wrobel

Background: Identifying the variability of footprint measurement collection techniques and the reliability of footprint measurements would assist with appropriate clinical foot posture appraisal. We sought to identify relationships between these measures in a healthy population. Methods: On 30 healthy participants, midgait dynamic footprint measurements were collected using an ink mat, paper pedography, and electronic pedography. The footprints were then digitized, and the following footprint indices were calculated with photo digital planimetry software: footprint index, arch index, truncated arch index, Chippaux-Smirak Index, and Staheli Index. Differences between techniques were identified with repeated-measures analysis of variance with post hoc test of Scheffe. In addition, to assess practical similarities between the different methods, intraclass correlation coefficients (ICCs) were calculated. To assess intrarater reliability, footprint indices were calculated twice on 10 randomly selected ink mat footprint measurements, and the ICC was calculated. Results: Dynamic footprint measurements collected with an ink mat significantly differed from those collected with paper pedography (ICC, 0.85–0.96) and electronic pedography (ICC, 0.29–0.79), regardless of the practical similarities noted with ICC values (P = .00). Intrarater reliability for dynamic ink mat footprint measurements was high for the footprint index, arch index, truncated arch index, Chippaux-Smirak Index, and Staheli Index (ICC, 0.74–0.99). Conclusions: Footprint measurements collected with various techniques demonstrate differences. Interchangeable use of exact values without adjustment is not advised. Intrarater reliability of a single method (ink mat) was found to be high. (J Am Podiatr Med Assoc 102(2): 130–138, 2012)


2001 ◽  
Vol 21 (10) ◽  
pp. 1146-1150 ◽  
Author(s):  
Jussi Hirvonen ◽  
Kjell Någren ◽  
Jaana Kajander ◽  
Jarmo Hietala

[11C]SCH 23390 is a standard ligand for positron emission tomography (PET) studies on striatal dopamine D1 receptors. Its usefulness for cortical D1 receptor quantification in human PET studies has been questioned but has not been addressed previously. The authors tested the reproducibility of [11C]SCH 23390 binding potential (BP) in cortical areas in five healthy volunteers using three-dimensional PET. Measurement of D1 receptor BP was reproducible in basal ganglia, as well as in all cortical areas studied (intraclass correlation coefficients between 0.81 and 0.92). The absolute variability in cortical areas was 9.21% ± 0.07%. The reproducibility of cortical D1 receptor BP measurement with [11C]SCH 23390 is equal to that observed with a more recent D1 -ligand, [11C]NNC 112. [11C]NNC 112 produces slightly higher specific-to-nonspecific binding ratios but has markedly slower kinetics resulting in a need for a longer scan time. These aspects should be considered when designing studies on the cortical D1 -like receptors.


2006 ◽  
Vol 3 (s2) ◽  
pp. S67-S77 ◽  
Author(s):  
Michelle Ihmels ◽  
Gregory J. Welk ◽  
James J. McClain ◽  
Jodee Schaben

Background:Advances in BIA offer practical alternative approaches to assessing body composition in young adolescents and have not been studied for comparability.Methods:This study compared reliability and convergent validity of three field tests (2-site skinfold, Omron and Tanita BIA devices) on young adolescents. Reliability was determined using intraclass correlation coefficients, convergent validity was examined by computing correlations among the three estimates, differences in estimated body fat values were evaluated using repeated-measures ANOVA, and classification agreement was computed for achieving FITNESSGRAM® Healthy Fitness Zone.Results:ICC values of all three measures exceeded .97. Correlations ranged from .74 to .81 for males and .79 to .91 for females. Classification agreement values ranged from 82.8% to 92.6%.Conclusions:Results suggest general agreement among the selected methods of body composition assessments in both boys and girls with the exception that percent body fat in boys by Tanita BIA is significantly lower than skinfold estimation.


2006 ◽  
Vol 43 (2) ◽  
pp. 129-137 ◽  
Author(s):  
Emeka Nkenke ◽  
Bernhard Lehner ◽  
Manuel Kramer ◽  
Gerd Haeusler ◽  
Stefanie Benz ◽  
...  

Objective To assess measurement errors of a novel technique for the three-dimensional determination of the degree of facial symmetry in patients suffering from unilateral cleft lip and palate malformations. Design Technical report, reliability study. Setting Cleft Lip and Palate Center of the University of Erlangen-Nuremberg, Erlangen, Germany. Patients The three-dimensional facial surface data of five 10-year-old unilateral cleft lip and palate patients were subjected to the analysis. Distances, angles, surface areas, and volumes were assessed twice. Main Outcome Measures Calculations were made for method error, intraclass correlation coefficient, and repeatability of the measurements of distances, angles, surface areas, and volumes. Results The method errors were less than 1 mm for distances and less than 1.5° for angles. The intraclass correlation coefficients showed values greater than .90 for all parameters. The repeatability values were comparable for cleft and noncleft sides. Conclusion The small method errors, high intraclass correlation coefficients, and comparable repeatability values for cleft and noncleft sides reveal that the new technique is appropriate for clinical use.


2016 ◽  
Vol 86 (6) ◽  
pp. 1004-1009 ◽  
Author(s):  
Asli Baysal ◽  
Ahmet Oguz Sahan ◽  
Mehmet Ali Ozturk ◽  
Tancan Uysal

ABSTRACT Objective: To evaluate the intraexaminer repeatability and interexaminer reproducibility of soft tissue landmarks on three-dimensional (3-D) stereophogrammetric images. Materials and Methods: Thirty-four stereophotogrammetric images were taken and 19 soft tissue points were identified. The images were obtained using the 3-DMD Face (3-DMD TM Ltd, Atlanta, Ga) system. Two examiners marked 34 images manually with a mouse-driven cursor 4 weeks apart. Intraexaminer marking differences were calculated and classified as &lt;0.5 mm, 0.5–1 mm, and &gt;1 mm. Intraclass correlation coefficients were calculated for intraexaminer reliability. A paired-samples t-test was used to evaluate the difference between the examiners. Interexaminer reproducibility was evaluated by kappa analysis. Statistical significance was set at P &lt; .05. Results: Only one landmark (labiale superior) had an intraexaminer marking difference less than 0.5 mm. Existing landmarks had an intraexaminer difference less than 1 mm, but higher than 0.5 mm. The intraclass correlation coefficients (ICCs) indicated good intraexaminer repeatability for both observers. The ICC range for examiners 1 and 2 was 0.986–1.000 and 0.990–1.000, respectively. Kappa scores showed good interexaminer agreement, especially on the z-axis. Conclusions: Except labiale superior, the soft tissue landmarks used in this study were shown to have moderate reproducibility, but the difference between the landmarks was less than 1 mm, and they had clinically acceptable reproducibility.


Author(s):  
Megan Sax van der Weyden ◽  
Christopher D. Black ◽  
Daniel Larson ◽  
Brian Rollberg ◽  
Jason A. Campbell

This investigation examined relationships between a Special Weapons and Tactics-specific fitness test (SORT) and an obstacle course (OC) used for qualification in fourteen male SWAT members from three local, regional police departments. The SORT included: squat, pushup, and lunge in 60 s; pullup hold; sled drag; and Yo-Yo Intermittent Recovery Test L1. The obstacle course included: 25 m sprint (repeated); window ascent; scale under a wall; 25 m serpentine run (repeated), body drag (20 m, repeated). Pearson coefficients examined SORT and OC relationships (p ≤ 0.05); intraclass correlation coefficients (ICC2,1) assessed agreement of SORT trials. Repeated measures ANOVA evaluated differences in SORT metrics across time. Coefficients of variation (COV) examined SORT scoring consistency. The YoYo test was related to all SORT assessments (r = −0.803–0.894), except sled drag. The remaining SORT metrics were related to ≥two tests. SORT COVs ranged from 0.77–13.26% for trials 1–2 but decreased between trials 2–3 (0.95–8.97%). The OC was associated with YoYo, lunges, squats and sled drag (r = −0.790, −0.730, −0.766, and 0.802, respectively). No differences (p > 0.05) existed across SORT trials for event scores. The SORT battery appears to be a valid and reliable testing measure to assess SWAT occupational specific fitness.


2020 ◽  
pp. 193229682097465
Author(s):  
Joel Willem Johan Lasschuit ◽  
Jill Featherston ◽  
Katherine Thuy Trang Tonks

Background: In an era of increasing technology and telehealth utilization, three-dimensional (3D) wound cameras promise reliable, rapid, and touch-free ulceration measurements. However, reliability data for commercially available devices in the diabetes foot service setting is lacking. We aimed to evaluate the reliability of diabetes-related foot ulceration measurement using a 3D wound camera in comparison to the routinely used ruler and probe. Method: Participants were prospectively recruited from a tertiary interdisciplinary diabetes foot service. Ulcerations were measured at each visit by two blinded observers, first by ruler and probe, and then using a 3D wound camera twice. Reliability was evaluated using intraclass correlation coefficients (ICC). Measurement methods were compared by Pearson correlation. Results: Sixty-three ulcerations affecting 38 participants were measured over 122 visits. Interobserver reliability of ruler measurement was excellent for estimated area (ICC 0.98, 95% CI 0.97-0.98) and depth (ICC 0.93, 95% CI 0.90-0.95). Intraobserver and interobserver reliability of the 3D wound camera area was excellent (ICC 0.96, 95%CI 0.95-0.97 and 0.97 95% CI 0.96-0.98, respectively). Depth was unrecordable in over half of 3D wound camera measurements, and reliability was inferior to probe measurement. Area correlation between methods was good ( R = 0.88 and 0.94 per observer); however, depth correlation was poor ( R = 0.49 and 0.65). Conclusions: 3D wound cameras offer practical advantages over ruler-based measurement. In diabetes-related foot ulceration, the reliability and comparability of area measurement was excellent across both methods, although depth was more reliably obtained by the probe. These limitations, together with cost, are important considerations if implementing this technology in diabetes foot care.


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