scholarly journals Prevalence of glaucoma in patients with obstructive sleep apnoea—a cross-sectional case-series

Eye ◽  
2007 ◽  
Vol 22 (9) ◽  
pp. 1105-1109 ◽  
Author(s):  
R E Bendel ◽  
J Kaplan ◽  
M Heckman ◽  
P A Fredrickson ◽  
S-C Lin
2011 ◽  
Vol 126 (2) ◽  
pp. 190-195 ◽  
Author(s):  
T Gutierrez ◽  
A C Leong ◽  
L Pang ◽  
E Chevretton ◽  
J-P Jeannon ◽  
...  

AbstractBackground:Obstructive sleep apnoea syndrome has been linked to obesity, nasal obstruction and adenotonsillar hypertrophy, but rarely to large thyroid goitres.Objective:To study the possible association between multinodular retrolaryngo-pharyngeal or retrosternal goitres and obstructive sleep apnoea syndrome.Subjects and methods:Retrospective case series at a tertiary referral centre (2000–2010). Study parameters included body mass index, Epworth sleep score and polysomnographic index.Results:Five patients were diagnosed with obstructive sleep apnoea syndrome and managed with nasal continuous positive airway pressure ventilation. Computed tomography showed a retrolaryngo-pharyngeal or retrosternal goitre with significant tracheal compression, displacement and laryngeal oedema. After total thyroidectomy, obstructive sleep apnoea resolved in all patients.Conclusion:Large, multinodular goitres with retrolaryngo-pharyngeal extension can cause obstructive sleep apnoea syndrome due to laryngeal compression and oedema. In such cases, total thyroidectomy enables resolution of symptoms. Patients with obstructive sleep apnoea syndrome should be screened for thyroid goitre.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
P. Philip ◽  
S. Bailly ◽  
M. Benmerad ◽  
J. A. Micoulaud-Franchi ◽  
Y. Grillet ◽  
...  

Abstract To evaluate the value of apnoea + hypopnoea index versus self-reported sleepiness at the wheel in anticipating the risk of sleepiness-related accidents in patients referred for obstructive sleep apnoea. A cross-sectional analysis of the French national obstructive sleep apnoea registry. 58,815 subjects referred for a suspicion of obstructive sleep apnoea were investigated by specific items addressing sleepiness at the wheel and sleepiness-related accidents. Apnoea + hypopnoea index was evaluated with a respiratory polygraphy or full polysomnography. Subjects had a median age of 55.6 years [45.3; 64.6], 65% were men, with a median apnoea + hypopnoea index of 22 [8; 39] events/h. Median Epworth sleepiness scale score was 9 [6; 13], 35% of the patients reported sleepiness at the wheel (n = 20,310), 8% (n = 4,588) reported a near-miss accident and 2% (n = 1,313) reported a sleepiness-related accident. Patients reporting sleepiness at the wheel whatever their obstructive sleep apnoea status and severity exhibited a tenfold higher risk of sleepiness-related accidents. In multivariate analysis, other predictors for sleepiness-related accidents were: male gender, ESS, history of previous near-miss accidents, restless leg syndrome/periodic leg movements, complaints of memory dysfunction and nocturnal sweating. Sleep apnoea per se was not an independent contributor. Self-reported sleepiness at the wheel is a better predictor of sleepiness-related traffic accidents than apnoea + hypopnoea index.


2015 ◽  
Vol 29 (2-3) ◽  
pp. 59-64
Author(s):  
Amrit Thapa ◽  
B. Jayan ◽  
Karan Nehra ◽  
Vishvaroop Nagpal ◽  
D. Bhattacharya

2020 ◽  
Vol 12 (S2) ◽  
pp. S129-S138
Author(s):  
Matteo Bradicich ◽  
Noriane A. Sievi ◽  
Fabian A. Grewe ◽  
Alessio Gasperetti ◽  
Malcolm Kohler ◽  
...  

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Ozaifa Kareem ◽  
Masood Tanvir ◽  
G. N. Bader

Abstract Background Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods A cross-sectional prospective cohort study of 504 patients with hypertension was undertaken at a tertiary care hospital of India for a period of 6 months. OSA was evaluated using the Berlin questionnaire while the daytime sleepiness was determined using Epworth Sleepiness Scale. Data analysis was done using SPSS v. 20. Results High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score >16) was found to be 32.5% (95% CI, p < 0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group were 37.41 ± 3.396 cm, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 35.45 ± 2.652 cm, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, p<0.001). The mean blood pressure (BP) ≥133.52/84.37 mmHg was recorded in patients with a high risk of OSA (95% CI, P < 0.05), and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P < 0.05). Conclusion In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from a proper evaluation of OSA.


2017 ◽  
Vol 4 (4) ◽  
pp. 894
Author(s):  
Raj Kumar Bhimwal ◽  
Mohan Makwana ◽  
Ravindra Jangid ◽  
Ratan Lal Bhati

Background: Obstructive Sleep Apnoea (OSA) has been too common yet under diagnosed clinical entity. It is associated with the metabolic syndrome, a cluster of cardio-metabolic parameters including central obesity, insulin resistance, hypertension and dyslipidemia. Obesity predisposes to both OSA and disorders in glucose metabolism. There is growing evidence that OSA confers an independent risk of adverse glucose metabolism.Methods: The present study conducted in the Department of Medicine at MDM Hospital attached to Dr. S.N. Medical College, Jodhpur, Rajasthan, India. Participants after understanding the study protocol and procedure, asked to give their written consent for the study. It was a cross sectional hospital based study in patients, screened at Diabetic clinic and those referred from the periphery. Berlin questionnaires and Epworth score are tools to screen for OSA attending the Medicine OPD and IPD, Dr. S. N. Medical College, Jodhpur. 50 patients with type 2 DM and 20 age and sex-matched controls were studied. Randomly selected T2DM subjects of age 20 to 75 years both sex with obesity, BMI>25 kg/m2, clinical history suggestive of OSA, Epworth score>6, Positive Berlin questionnaires were included in the study. Acute and unstable medical condition e.g. CHF, CRF, COPD, Recent stroke, Acute ACS, Pregnant women were excluded.Results: In the study OSA was prevalent in the diabetic population (54%), Mean age of the study population was 54.96±9.35 years. OSA was found to be increased with increasing age with maximum prevalence in ≥60 year’s age group. OSA was more prevalent in the male population (64.29%), in urban population. Snoring, observed sleep apnoea, restless sleep/insomnia, excessive daytime sleepiness and non-refreshing sleep were significantly associated with OSA. (P<0.001). Prevalence of OSA was more in high BMI group (≥35 kg/m2), OSA increased with increase in neck circumference. OSA was more in subjects with uncontrolled diabetes (blood sugar>200 mg/dl), smokers and alcoholics.Conclusions: This study shows that OSA has a high prevalence in subjects with T2DM and identify several factors that may be associated with its presence in the diabetic population. OSA can be usefully and easily assessed in an outpatient setting by using a portable device such as Apnea Link. Clinicians should increase patients' awareness of the signs and symptoms of OSA and refer for sleep studies when appropriate. Once diagnosed, patients should be encouraged to adhere to CPAP treatment in order to halt progression and prevent complications.


2019 ◽  
Vol 46 (2) ◽  
pp. 22-25
Author(s):  
Syed Hasan Imam Al-Masum ◽  
Syed AM Asfarul Abedin ◽  
Anup Kumar Chowdhury ◽  
Bishwojit Kumar Saha ◽  
Md Nazmul Islam ◽  
...  

Obstructive sleep apnoea (OSA) is a condition characterized by episodic partial or complete obstruction of the upper airway during sleep. This cause apnoea or cessation of breathing. During sleep, muscles around the airway relax causing the throat and upper airway to narrow. This leads to snoring, but it can also lead to the airway being blocked. Trying to breathe against a blocked airway causes oxygen levels to fall and carbon dioxide to rise. This cross-sectional study was conducted in Department of ENT, Dhaka Shishu (Children) Hospital and Dhaka Medical College Hospital from April to September’2015. The purpose of the study was to prevent significant morbidity and enhancement of child growth. One hundred children of OSA were studied by detail history and clinical examination. All children whose parents consulted their ENT surgeon in Dhaka Shishu(Children) Hospital and DMCH for snoring or laboured breathing during sleep (nocturnal sweating particularly in the nuchal area, unusual sleeping positions, restless sleep, awakening and excessive movements, intercostals recession and dry mouth) were included in the study. More common predisposing conditions for OSA were obesity and Craniofacial anomalies which were 34% and 27% respectively. In present study most of the children (73%) were managed by Adenotonsillectomy and 27% children were manage by Adenoidectomy. Outcome data have demonstrated that surgical therapy can be successful in the treatment of OSA. Bangladesh Med J. 2017 May; 46 (2): 22-25


2021 ◽  
Vol 11 (9) ◽  
pp. 1160
Author(s):  
Elizabeth A. Hill ◽  
Linda J. Williams ◽  
Sally-Ann Cooper ◽  
Renata L. Riha

Prior to this study, the prevalence of obstructive sleep apnoea/hypopnoea syndrome (OSAHS) in adults with Down syndrome was unknown. We hypothesized that unrecognised OSAHS could have an additional deleterious impact on mood and behavioural disturbances in this group of people. Aims: To assess the prevalence of OSAHS in adults with Down syndrome in the United Kingdom, subjectively and objectively, and ascertain its association with diurnal behavioural disturbances. Method: Cross-sectional questionnaire study with home sleep apnoea testing (HSAT) during 2011–2015 across the four nations of the United Kingdom. Participants were adults aged ≥16 years with Down syndrome. Main outcome measures were: self- or caregiver-completed questionnaire data, including the Pictorial Epworth Sleepiness Scale (pESS), selected domains of the Developmental Behavioural Checklist for Adults (DBC-A), anthropometric measures, and symptoms of OSAHS. Objective prevalence was undertaken in a sample of responders using HSAT. Results: Responses were received from 1321/5270 participants (25%), with 1105 valid responses (21%). Eighty-one participants (7%) reported a prior diagnosis of OSA, of whom 38 were receiving therapy. Using validated algorithms, a diagnosis of OSAHS was probable in 366 participants (35%), who were younger, with higher BMI and higher mean total pESS (p < 0.0001). A total of 23% of participants had a pESS > 10. OSAHS was a strong marker for behavioural disturbances on the DBC-A depression, disruption and anti-social subscales (p < 0.001). Of 149 individuals who underwent HSAT, 42% were diagnosed with OSAHS. Conclusions: Untreated OSAHS in Down syndrome is common and associated with behavioural and mood disturbances. Improving awareness of OSAHS amongst adults with Down syndrome, their families and healthcare professionals is essential.


SLEEP ◽  
2021 ◽  
Author(s):  
Hoi Man Yuen ◽  
Chun Ting Au ◽  
Winnie Chiu Wing Chu ◽  
Albert Martin Li ◽  
Kate Ching-ching Chan

Abstract Study Objectives Childhood obstructive sleep apnoea (OSA) is an important and prevalent disease. A short lingual frenulum is a risk factor for OSA, but whether tongue mobility also plays a role in OSA aetiology remains unknown. This study aimed to examine tongue mobility in children with and without OSA. We hypothesized that reduced tongue mobility was associated with OSA. We also evaluated the relationship between tongue mobility and craniofacial profile. Methods This was a cross-sectional case-control study. Prepubertal Chinese children aged 5-12 years, suspected to have OSA were recruited from our sleep disorder clinic. All subjects underwent overnight polysomnography (PSG). The lingual frenulum was evaluated based on tongue mobility and free tongue length. Craniofacial measurements were assessed by lateral cephalometry. Results Eighty-two subjects (mean age: 8.32 ± 1.70 years, 57 males) were recruited. The mean tongue mobility was 58.2 (±19)% and 67.4 (±15)% (p=0.019) in subjects with and without OSA, respectively. Tongue mobility was inversely correlated with OAHI (r=-0.218, p=0.049). In multivariate logistic regression, low tongue mobility was independently associated with a higher risk of OSA after adjustment for age, sex, BMI z-score, presence of large tonsils and turbinates and nocturnal oral breathing (odds ratio=3.65, 95% CI= 1.22-11.8). Tongue mobility was found to correlate with the cranial base angle (Ba-S-N) (r=0.262, p=0.018), which determines the relative position of the mandible. Conclusions In pre-pubertal children, reduced tongue mobility is associated with the occurrence and severity of OSA. Assessing tongue mobility is recommended in childhood OSA management.


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