Impact of different PEGylation patterns on the long-term bio-stability of colloidal mesoporous silica nanoparticles

2010 ◽  
Vol 20 (39) ◽  
pp. 8693 ◽  
Author(s):  
Valentina Cauda ◽  
Christian Argyo ◽  
Thomas Bein
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles

scholarly journals Electrospun Antimicrobial Films of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Containing Eugenol Essential Oil Encapsulated in Mesoporous Silica Nanoparticles

Nanomaterials ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 227 ◽  
Author(s):  
Beatriz Melendez-Rodriguez ◽  
Kelly J. Figueroa-Lopez ◽  
Andrea Bernardos ◽  
Ramón Martínez-Máñez ◽  
Luis Cabedo ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Food Packaging ◽  
Mesoporous Silica Nanoparticles ◽  
Life Extension ◽  
Release Capacity ◽  
Active Food Packaging ◽  
Closed Systems

The main goal of this study was to develop poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) films with long-term antimicrobial capacity of interest in food packaging applications. To this end, eugenol was first highly efficiently encapsulated at 50 wt.-% in the pores of mesoporous silica nanoparticles by vapor adsorption. The eugenol-containing nanoparticles were then loaded in the 2.5–20 wt.-% range into PHBV by electrospinning and the resultant electrospun composite fibers were annealed at 155 °C to produce continuous films. The characterization showed that the PHBV films filled with mesoporous silica nanoparticles containing eugenol present sufficient thermal resistance and enhanced mechanical strength and barrier performance to water vapor and limonene. The antimicrobial activity of the films was also evaluated against foodborne bacteria for 15 days in open vs. closed conditions in order to simulate real packaging conditions. The electrospun PHBV films with loadings above 10 wt.-% of mesoporous silica nanoparticles containing eugenol successfully inhibited the bacterial growth, whereas the active films stored in hermetically closed systems increased their antimicrobial activity after 15 days due to the volatile portion accumulated in the system’s headspace and the sustained release capacity of the films. The resultant biopolymer films are, therefore, potential candidates to be applied in active food packaging applications to provide shelf life extension and food safety.

Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery

2016 ◽  
Vol 4 (15) ◽  
pp. 2646-2653 ◽  
Author(s):  
Yue Wang ◽  
Yusilawati Ahmad Nor ◽  
Hao Song ◽  
Yannan Yang ◽  
Chun Xu ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Bacterial Inhibition ◽  
Large Pore ◽  
Enzyme Delivery

Small-sized silica nanoparticles with large dendritic mesopores demonstrate a superior antimicrobial enzyme delivery efficacy with long-term bacterial inhibition.

Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
High Surface ◽  
Delivery Systems ◽  
Surface Reactivity ◽  
External Stimulus ◽  
Recent Advances

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.

Fluorescent spherical mesoporous silica nanoparticles loaded with emodin: Synthesis, cellular uptake and anticancer activity

2021 ◽  
Vol 119 ◽  
pp. 111619
Author(s):  
Paul Jänicke ◽  
Claudia Lennicke ◽  
Annette Meister ◽  
Barbara Seliger ◽  
Ludger A. Wessjohann ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Anticancer Activity ◽  
Silica Nanoparticles ◽  
Cellular Uptake ◽  
Mesoporous Silica Nanoparticles
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