An online coupled breast cancer cell membrane chromatography with HPLC/MS for screening active compounds from Fructus evodiae

2013 ◽  
Vol 5 (20) ◽  
pp. 5767 ◽  
Author(s):  
Xilong Yuan ◽  
Bing Zhang ◽  
Yunan Wang ◽  
Jing Ma ◽  
Xiaofang Hou
Keyword(s):  
Breast Cancer ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Active Compounds ◽  
Cell Membrane Chromatography ◽  
Membrane Chromatography

scholarly journals Aberrant Expression of Novel and Previously Described Cell Membrane Markers in Human Breast Cancer Cell Lines and Tumors

2005 ◽  
Vol 11 (12) ◽  
pp. 4357-4364 ◽  
Author(s):  
Huayi Huang ◽  
Jeff Groth ◽  
Khalid Sossey-Alaoui ◽  
Lesleyann Hawthorn ◽  
Stephanie Beall ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Membrane ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Human Breast Cancer ◽  
Human Breast Cancer Cell ◽  
Breast Cancer Cell Lines ◽  
Human Breast ◽  
Aberrant Expression

Cell membrane and intracellular expression of toll-like receptor 9 (TLR9) in colorectal cancer and breast cancer cell-lines

2017 ◽  
Vol 18 (4) ◽  
pp. 375-380 ◽  
Author(s):  
Shadab Shahriari ◽  
Somayeh Rezaeifard ◽  
Hamid Reza Moghimi ◽  
Mohammad Reza Khorramizadeh ◽  
Zahra Faghih
Keyword(s):  
Breast Cancer ◽  
Colorectal Cancer ◽  
Cell Membrane ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Toll Like Receptor ◽  
Intracellular Expression

Co-biomembrane coated Fe3O4/MnO2 multifunctional nanoparticles for targeted delivery and enhanced hemodynamic/photothermal/chemo therapy

2021 ◽  
Author(s):  
Yingshu Guo ◽  
Xiaofei Zheng ◽  
Tingting Gai ◽  
Zhiyong Wei ◽  
Shu-Sheng Zhang
Keyword(s):  
Breast Cancer ◽  
Escherichia Coli ◽  
Drug Delivery ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Targeted Delivery ◽  
Membrane System ◽  
Multifunctional Nanoparticles ◽  
Mcf 7

Here, the co-membrane system of MCF-7 breast cancer cell membrane (MM) and Escherichia coli membrane (EM)-coated Fe3O4/MnO2 multifunctional composite nanoparticles loaded with DOX (Fe3O4/MnO2/MM/EM/D) was used for targeting drug delivery...

scholarly journals Progesterone receptor enhances breast cancer cell motility and invasion via extranuclear activation of focal adhesion kinase

2010 ◽  
Vol 17 (2) ◽  
pp. 431-443 ◽  
Author(s):  
Xiao-Dong Fu ◽  
Lorenzo Goglia ◽  
Angel Matias Sanchez ◽  
Marina Flamini ◽  
Maria S Giretti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Membrane ◽  
Progesterone Receptor ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Focal Adhesion ◽  
Breast Cancer Cells ◽  
Cell Movement ◽  
Migration And Invasion

While progesterone plays multiple roles in the process of breast development and differentiation, its role in breast cancer is less understood. We have shown previously that progestins stimulate breast cancer cell migration and invasion because of the activation of rapid signaling cascades leading to modifications in the actin cytoskeleton and cell membrane that are required for cell movement. In this study, we have investigated the effects of progesterone on the formation of focal adhesion (FA) complexes, which provide anchoring sites for cell attachment to the extracellular matrix during cell movement and invasion. In T47-D breast cancer cells, progesterone rapidly enhances FA kinase (FAK) phosphorylation at Tyr397 in a time- and concentration-dependent manner. As a result, exposure to progesterone leads to increased formation of FA complexes within specialized cell membrane protrusions. The cascade of events required for this phenomenon involves progesterone receptor interaction with the tyrosine kinase c-Src, which activates the phosphatidylinositol-3-kinase/Akt pathway and the small GTPase RhoA/Rho-associated kinase complex. In the presence of progesterone, T47-D breast cancer cells display enhanced horizontal migration and invasion of three-dimensional matrices, which is reversed by small interfering RNAs abrogating FAK. In conclusion, progesterone promotes breast cancer cell movement and invasion by facilitating the formation of FA complexes via the rapid regulation of FAK. These results provide novel mechanistic views on the effects of progesterone on breast cancer progression, and may in the future be helpful to develop new strategies for the treatment of endocrine-sensitive breast cancers.

scholarly journals Increasing roughness of the human breast cancer cell membrane through incorporation of gold nanoparticles

2016 ◽  
Vol Volume 11 ◽  
pp. 5149-5161 ◽  
Author(s):  
Carlos Lara Cruz ◽  
Javier Jimenez Salazar ◽  
Eva Ramon Gallegos ◽  
Pablo Damian Matsumura ◽  
Nikola Batina
Keyword(s):  
Breast Cancer ◽  
Gold Nanoparticles ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Human Breast Cancer ◽  
Human Breast Cancer Cell ◽  
Human Breast

Mechanical Properties of Breast Cancer Cell Membrane Studied with Optical Tweezers

2004 ◽  
Vol 21 (12) ◽  
pp. 2543-2546 ◽  
Author(s):  
Guo Hong-Lian ◽  
Liu Chun-Xiang ◽  
Duan Jian-Fa ◽  
Jiang Yu-Qiang ◽  
Han Xue-Hai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mechanical Properties ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Optical Tweezers ◽  
Breast Cancer Cell

Comprehensive two-dimensional PC-3 prostate cancer cell membrane chromatography for screening anti-tumor components from Radix Sophorae flavescentis

2017 ◽  
Vol 40 (13) ◽  
pp. 2688-2693 ◽  
Author(s):  
Qiang Wang ◽  
Junnan Xu ◽  
Xiang Li ◽  
Dawei Zhang ◽  
Yong Han ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Two Dimensional ◽  
Cell Membrane Chromatography ◽  
Membrane Chromatography
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