Affinity of zinc and copper ions for insulin monomers

Metallomics ◽  
2014 ◽  
Vol 6 (7) ◽  
pp. 1296-1300 ◽  
Author(s):  
Julia Gavrilova ◽  
Vello Tõugu ◽  
Peep Palumaa

Zinc is an essential trace element involved in the correct packing and storage of insulin.

Geology ◽  
2021 ◽  
Author(s):  
Simon Turner ◽  
Heather Handley ◽  
Paul Hesse ◽  
Bruce Schaefer ◽  
Anthony Dosseto

Dust plays important roles in the environment, and there has been much interest in the formation, provenance, and age of the world’s dust deposits. Ongoing debates are concerned with the importance of glacial grinding versus eolian abrasion and fluvial transport in the formation of silt-sized particles. Short-lived uranium-series isotopes afford new insights because they can be used both for provenance fingerprinting and for constraining the integrated age of chemical and physical weathering and subsequent transport and storage of sediments. Here we present trace element and Sr, Nd, and U-series isotope analyses from a number of Australian dusts and suspended river sediments remobilized during floods a year later. The inferred ages of the Australian dust appear to be linked to aridification and the loss of inland megalakes ~30–120 k.y. ago. This provides preliminary evidence that the age of dust may provide a new hydrological indicator in arid environments.


2020 ◽  
Vol 11 (1) ◽  
pp. 200-210 ◽  
Author(s):  
Yu Chen ◽  
Yi-fan Zhao ◽  
Jing Yang ◽  
Hong-yuan Jing ◽  
Wan Liang ◽  
...  

Selenium (Se) is an essential trace element for living organisms and plays diverse biological roles.


2005 ◽  
Vol 170 (12) ◽  
pp. 1048-1052 ◽  
Author(s):  
James P. McClung ◽  
Angus G. Scrimgeour

Metallomics ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 868-875 ◽  
Author(s):  
Norika Goto ◽  
Hirokazu Hara ◽  
Mao Kondo ◽  
Naomi Yasuda ◽  
Tetsuro Kamiya ◽  
...  

Copper (Cu) is an essential trace element and acts as a redox cofactor for many enzymes; however, excess Cu is toxic to cells.


2009 ◽  
Vol 106 (26) ◽  
pp. 10859-10864 ◽  
Author(s):  
S. Yamaguchi ◽  
C. Miura ◽  
K. Kikuchi ◽  
F. T. Celino ◽  
T. Agusa ◽  
...  

Author(s):  
AWANISH KUMAR ◽  
KUMAR SURANJIT PRASAD

Biosynthesis is an eloquent, safe, biocompatible, eco-friendly, and recyclable way of preparing selenium nanoparticles (SeNPs). Selenium occurs in multiple oxidation states, for example, +6, +4, 0, or −2. Selenium (Se) is an essential trace element with a very narrow margin between the lowest acceptable levels of intake and toxicity. Selenium is an essential trace element required for all living organisms. Despite its essentiality, selenium is a potentially toxic element to natural ecosystems due to its bioaccumulation potential that is why it is biologically available in the environment. Selenium is a trace element commonly found in materials of the earth’s crust, and it is essential for humans, animals, and plants. Oxyanions of selenium, that is selenite and selenate, are biologically available. Selenium in the form of selenate ion (SeO42−) is more toxic to most organisms than selenite (SeO32−). Contrarily, elemental selenium (Se0) is inOsoluble and less toxic in comparison to other forms of selenium. Nanoselenium (Se0) in the range of 100–500 nm has similar bioavailability to other forms of selenium into plants, animals, humans, and microorganisms. Biologically synthesized SeNP has many biological applications in the field of medical and pharmaceutical research to combat threats to human health. Biogenic SeNPs have anticancer (cytotoxic) activity, antioxidant activity, and antimicrobial activity. Researches are going on with special interest of SeNPs. Conjugation of antibiotics with SeNPs enhances their anticancer efficacy. SeNPs have also applications in nanobiosensors and environmental remediation.


Antioxidants ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 145 ◽  
Author(s):  
Athanasios C. Pappas ◽  
Evangelos Zoidis ◽  
Stella E. Chadio

Selenium (Se) is an essential trace element of fundamental importance to health due to its antioxidant, anti-inflammatory, and chemopreventive properties, attributed to its presence within at least 25 selenoproteins (Sel). In this review, we describe some of the recent progress, in our understanding, on the impact of maternal Se intake during the periconceptional period on offspring development and health. Maternal nutrition affects the performance and health of the progeny, and both maternal and offspring Se supplementations are essential for the optimal health and antioxidant protection of the offspring. The case of Se in epigenetic programming and early life nutrition is also discussed.


2010 ◽  
Vol 38 (3) ◽  
pp. 372-377 ◽  
Author(s):  
Y. Srinivasa Reddy ◽  
Raghu Pullakhandam ◽  
K. V. Radha Krishna ◽  
P. Uday Kumar ◽  
B. Dinesh Kumar

2020 ◽  
Vol 37 (10) ◽  
pp. 188-193
Author(s):  
Cebrail ÅžimÅŸek ◽  
Gülden Sarı ◽  
Bilge Akgündüz ◽  
Yetkin AÄŸaçkıran ◽  
V. Ali Türksoy ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document