Magnetite/dextran-functionalized graphene oxide nanosheets for in vivo positive contrast magnetic resonance imaging

Purpose: The aim of this study was to assess the volumetry of the hippocampus in the Leber’s hereditary optic neuropathy (LHON) of blind patients. Methods: A total of 25 patients with LHON were randomly included into the study from the national health database. A total of 15 patients were selected according to the inclusion criteria. The submillimeter segmentation of the hippocampus was based on three-dimensional spoiled gradient recalled acquisition in steady state (3D-SPGR) BRAVO 7T magnetic resonance imaging (MRI) protocol. Results: Statistical analysis revealed that compared to healthy controls (HC), LHON subjects had multiple significant differences only in the right hippocampus, including a significantly higher volume of hippocampal tail (p = 0.009), subiculum body (p = 0.018), CA1 body (p = 0.002), hippocampal fissure (p = 0.046), molecular layer hippocampus (HP) body (p = 0.014), CA3 body (p = 0.006), Granule Cell (GC) and Molecular Layer (ML) of the Dentate Gyrus (DG)–GC ML DG body (p = 0.003), CA4 body (p = 0.001), whole hippocampal body (p = 0.018), and the whole hippocampus volume (p = 0.023). Discussion: The ultra-high-field magnetic resonance imaging allowed hippocampus quality visualization and analysis, serving as a powerful in vivo diagnostic tool in the diagnostic process and LHON disease course assessment. The study confirmed previous reports regarding volumetry of hippocampus in blind individuals.

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Highly Selective Heavy Metal Ions Membranes Combining Sulfonated Polyethersulfone and Self-assembled Manganese Oxide Nanosheets on Positively Functionalized Graphene Oxide Nanosheets

Chemical Engineering Journal ◽

10.1016/j.cej.2021.131267 ◽

2021 ◽

pp. 131267

Author(s):

Yazan Ibrahim ◽

Vijay S Wadi ◽

Mariam Ouda ◽

Vincenzo Naddeo ◽

Fawzi Banat ◽

...

Keyword(s):

Heavy Metal ◽

Graphene Oxide ◽

Metal Ions ◽

Manganese Oxide ◽

Heavy Metal Ions ◽

Functionalized Graphene ◽

Graphene Oxide Nanosheets ◽

Functionalized Graphene Oxide ◽

Self Assembled ◽

Sulfonated Polyethersulfone

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In Vivo Tracking of the Human Patella Using Cine Phase Contrast Magnetic Resonance Imaging

Journal of Biomechanical Engineering ◽

10.1115/1.2800868 ◽

1999 ◽

Vol 121 (6) ◽

pp. 650-656 ◽

Cited By ~ 86

Author(s):

F. T. Sheehan ◽

F. E. Zajac ◽

J. E. Drace

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Knee Joint ◽

Phase Contrast ◽

Three Dimensional ◽

Resonance Imaging ◽

Contrast Magnetic Resonance ◽

Knee Joint Kinematics ◽

Cine Phase Contrast

Improper patellar tracking is often considered to be the cause of patellar-femoral pain. Unfortunately, our knowledge of patellar-femoral-tibial (knee) joint kinematics is severely limited due to a lack of three-dimensional, noninvasive, in vivo measurement techniques. This study presents the first large-scale, dynamic, three-dimensional, noninvasive, in vivo study of nonimpaired knee joint kinematics during volitional leg extensions. Cine-phase contrast magnetic resonance imaging was used to measure the velocity profiles of the patella, femur, and tibia in 18 unimpaired knees during leg extensions, resisted by a 34 N weight. Bone displacements were calculated through integration and then converted into three-dimensional orientation angles. We found that the patella displaced laterally, superiorly, and anteriorly as the knee extended. Further, patellar flexion lagged knee flexion, patellar tilt was variable, and patellar rotation was fairly constant throughout extension.

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