Real time monitoring of aminothiol level in blood using a near-infrared dye assisted deep tissue fluorescence and photoacoustic bimodal imaging

Anin vitroandin vivodrug-reporting system is developed for real-time monitoring of drug release via the analysis of the concurrently released near-infrared fluorescence dye.

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Process modeling and control applied to real-time monitoring of distillation processes by near-infrared spectroscopy

Analytica Chimica Acta ◽

10.1016/j.aca.2017.07.038 ◽

2017 ◽

Vol 985 ◽

pp. 41-53 ◽

Cited By ~ 4

Author(s):

Rodrigo R. de Oliveira ◽

Ricardo H.P. Pedroza ◽

A.O. Sousa ◽

Kássio M.G. Lima ◽

Anna de Juan

Keyword(s):

Infrared Spectroscopy ◽

Real Time ◽

Near Infrared Spectroscopy ◽

Process Modeling ◽

Near Infrared ◽

Real Time Monitoring ◽

Modeling And Control ◽

And Control

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Ratiometric and light-up near-infrared fluorescent DCM-based probe for real-time monitoring endogenous tyrosinase activity

Dyes and Pigments ◽

10.1016/j.dyepig.2018.11.019 ◽

2019 ◽

Vol 162 ◽

pp. 802-807 ◽

Cited By ~ 7

Author(s):

Qiang Li ◽

Chenxu Yan ◽

Jie Zhang ◽

Zhiqian Guo ◽

Wei-Hong Zhu

Keyword(s):

Real Time ◽

Near Infrared ◽

Tyrosinase Activity ◽

Real Time Monitoring

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NIR-Responsive Lysosomotropic Phototrigger: ʽAIE + ESIPTʼ Active Naphthalene Based Single Component Photoresponsive Nanocarrier with Two-Photon Uncaging and Real-Time Monitoring Ability

10.33774/chemrxiv-2021-nftrb ◽

2021 ◽

Author(s):

Biswajit Roy ◽

Rakesh Mengji ◽

Samrat Roy ◽

Bipul Pal ◽

Avijit Jana ◽

...

Keyword(s):

Drug Delivery ◽

Drug Release ◽

Real Time ◽

Near Infrared ◽

Single Component ◽

Photon Absorption ◽

Real Time Monitoring ◽

Two Photon ◽

Nir Light

In recent times, organelle-targeted drug delivery systems gained tremendous attention due to the site specific delivery of active drug molecules resulting in enhanced bioefficacy. In this context, the phototriggered drug delivery system (DDS) for releasing an active molecule is superior as it provides spatial and temporal control over the release. So far, near infrared (NIR) light responsive organelle targeted DDS has not yet been developed. Hence, we introduced a two-photon NIR-light responsive lysosome targeted ʽAIE + ESIPTʼ active single component DDS based on naphthalene chromophore. The Two-photon absorption cross-section of our DDS is 142 GM at 850 nm. The DDS was converted into pure organic nanoparticles for biological applications. Our nano-DDS is capable of selective targeting, AIE-luminogenic imaging, and drug release within the lysosome. In vitro studies using cancerous cell lines showed that our single component photoresponsive nanocarrier exhibited enhanced cytotoxicity and real-time monitoring ability of the drug release.

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Near-IR-induced dissociation of thermally-sensitive star polymers

Chemical Science ◽

10.1039/c6sc04650a ◽

2017 ◽

Vol 8 (3) ◽

pp. 1815-1821 ◽

Cited By ~ 24

Author(s):

Yuqiong Dai ◽

Hao Sun ◽

Sunirmal Pal ◽

Yunlu Zhang ◽

Sangwoo Park ◽

...

Keyword(s):

Near Infrared ◽

Star Polymers ◽

Tissue Penetration ◽

Triggered Release ◽

Deep Tissue ◽

Responsive Systems ◽

Nir Light ◽

Near Ir ◽

Triggering Events ◽

Spatiotemporal Control

Responsive systems sensitive to near-infrared (NIR) light are promising for triggered release due to efficient deep tissue penetration of NIR irradiation relative to higher energy sources (e.g., UV), allowing for spatiotemporal control over triggering events with minimal potential for tissue damage.

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