Non-enzymatic amperometric sensing of glucose by employing sucrose templated microspheres of copper oxide (CuO)

2016 ◽  
Vol 45 (13) ◽  
pp. 5833-5840 ◽  
Author(s):  
Mohit Saraf ◽  
Kaushik Natarajan ◽  
Shaikh M. Mobin
Keyword(s):  
Detection Limit ◽  
Copper Oxide ◽  
Glucose Sensor ◽  
Hydrothermal Reaction ◽  
Copper Nitrate ◽  
Good Sensitivity ◽  
Detection Range ◽  
Low Detection Limit ◽  
Linear Detection ◽  
Amperometric Sensing

An enzymeless glucose sensor (MCSPE) based on copper oxide microspheres (CMS) prepared by hydrothermal reaction of copper nitrate and sucrose, can sense glucose in a wide linear detection range with good sensitivity and low detection limit.

scholarly journals Nanostructured copper selenide as an ultrasensitive and selective non-enzymatic glucose sensor

2021 ◽  
Author(s):  
Siddesh Umapathi ◽  
Harish Singh ◽  
Jahangir Masud ◽  
Manashi Nath
Keyword(s):  
Detection Limit ◽  
High Efficiency ◽  
Glucose Sensor ◽  
High Sensitivity ◽  
Copper Selenide ◽  
Glucose Detection ◽  
Applied Potential ◽  
Detection Range ◽  
Low Detection Limit ◽  
Linear Detection

CuSe nanostructures exhibit high-efficiency for glucose detection with high sensitivity (19.419 mA mM−1 cm−2) and selectivity at low applied potential (0.15 V vs. Ag|AgCl), low detection limit (0.196 μM) and linear detection range (100 nM to 40 μM).

scholarly journals Cu-Based Conductive MOF Grown in situ on Cu Foam as a Highly Selective and Stable Non-Enzymatic Glucose Sensor

2021 ◽  
Vol 9 ◽  
Author(s):  
Qin Hu ◽  
Jie Qin ◽  
Xiao-Feng Wang ◽  
Guang-Ying Ran ◽  
Qiang Wang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Glucose Sensor ◽  
Electrochemical Sensors ◽  
Hydrothermal Reaction ◽  
Metal Organic Framework ◽  
Copper Acetate ◽  
Fast Response ◽  
Glucose Detection ◽  
Low Detection Limit ◽  
Cu Foam

A non-enzymatic electrochemical sensor for glucose detection is executed by using a conductive metal–organic framework (MOF) Cu-MOF, which is built from the 2,3,6,7,10,11-hexahydroxytriphenylene (HHTP) ligand and copper acetate by hydrothermal reaction. The Cu-MOF demonstrates superior electrocatalytic activity for glucose oxidation under alkaline pH conditions. As an excellent non-enzymatic sensor, the Cu-MOF grown on Cu foam (Cu-MOF/CF) displays an ultra-low detection limit of 0.076 μM through a wide concentration range (0.001–0.95 mM) and a strong sensitivity of 30,030 mA μM−1 cm−2. Overall, the Cu-MOF/CF exhibits a low detection limit, high selectivity, excellent stability, fast response time, and good practical application feasibility for glucose detection and can promote the development of MOF materials in the field of electrochemical sensors.

A nanofluidic device for ultrasensitive and label-free detection of tetracycline in association with γ-cyclodextrin and GO

2021 ◽  
Vol 13 (15) ◽  
pp. 1832-1838
Author(s):  
Jiaxi Cheng ◽  
Fenghua Jiang ◽  
Siqi Zhang
Keyword(s):  
Detection Limit ◽  
Water Samples ◽  
Recovery Rate ◽  
Label Free ◽  
Detection Range ◽  
Low Detection Limit ◽  
Sensing Platform ◽  
Label Free Detection ◽  
Nanofluidic Device

We develop a label-free, sensitive and selective nanochannel sensing platform for detection of TC. The nanosensor provided a low detection limit, a wide detection range and excellent recovery rate in different water samples.

scholarly journals Single-Atom Cobalt-Based Electrochemical Biomimetic Uric Acid Sensor with Wide Linear Range and Ultralow Detection Limit

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Fang Xin Hu ◽  
Tao Hu ◽  
Shihong Chen ◽  
Dongping Wang ◽  
Qianghai Rao ◽  
...  
Keyword(s):  
Uric Acid ◽  
Detection Limit ◽  
Single Atom ◽  
Practical Application ◽  
Oxidation Of Co ◽  
Renal Disorder ◽  
Detection Range ◽  
Low Detection Limit ◽  
Doped Graphene ◽  
Better Than

Abstract Uric acid (UA) detection is essential in diagnosis of arthritis, preeclampsia, renal disorder, and cardiovascular diseases, but it is very challenging to realize the required wide detection range and low detection limit. We present here a single-atom catalyst consisting of Co(II) atoms coordinated by an average of 3.4 N atoms on an N-doped graphene matrix (A–Co–NG) to build an electrochemical biomimetic sensor for UA detection. The A–Co–NG sensor achieves a wide detection range over 0.4–41,950 μM and an extremely low detection limit of 33.3 ± 0.024 nM, which are much better than previously reported sensors based on various nanostructured materials. Besides, the A–Co–NG sensor also demonstrates its accurate serum diagnosis for UA for its practical application. Combination of experimental and theoretical calculation discovers that the catalytic process of the A–Co–NG toward UA starts from the oxidation of Co species to form a Co3+–OH–UA*, followed by the generation of Co3+–OH + *UA_H, eventually leading to N–H bond dissociation for the formation of oxidized UA molecule and reduction of oxidized Co3+ to Co2+ for the regenerated A–Co–NG. This work provides a promising material to realize UA detection with wide detection range and low detection limit to meet the practical diagnosis requirements, and the proposed sensing mechanism sheds light on fundamental insights for guiding exploration of other biosensing processes.

In-Vitro Diagnosis of Colon Cancer Using Bio-Functionalized Magnetic Nanoparticles

2011 ◽  
Author(s):  
Chin-Yih Hong ◽  
Shieh-Yueh Yang ◽  
K. W. Huang ◽  
Herng-Er Horng ◽  
Hong-Chang Yang
Keyword(s):  
Colon Cancer ◽  
Magnetic Nanoparticles ◽  
Detection Limit ◽  
Dynamic Range ◽  
Risk Level ◽  
Enzyme Linked Immunosorbent Assay ◽  
Detection Range ◽  
Low Detection Limit ◽  
In Vitro Diagnosis

The popular bio-marker for colon cancer is carcinoembryonic antigen (CEA). By conjugating anti-CEA onto magnetic nanoparticles, CEA can be specially labeled and detected by measuring magnetic signals via immunomagnetic reduction (IMR). The low detection limit and detection range of IMR on CEA are investigated. The results are compared with those by using the existing assay, such as enzyme-linked immunosorbent assay (ELISA). It is evidenced that IMR has sensitivity much higher than that of ELISA. The low detection limit is below the normal level of CEA concentration of clinic practice and is suitable for early-stage in-vitro diagnosis for colon cancer. Furthermore, the dynamic range of detection for the CEA concentration using IMR extends well above the threshold of high risk level of colorectal carcinoma in current diagnosing practice. Therefore, IMR is also suitable in other stages diagnosis for colon cancer development.

Mesoporous Ni0.3Co2.7O4 hierarchical structures for effective non-enzymatic glucose detection

RSC Advances ◽  
2014 ◽  
Vol 4 (63) ◽  
pp. 33514-33519 ◽  
Author(s):  
Yuanying Liu ◽  
Youjuan Zhang ◽  
Ting Wang ◽  
Panpan Qin ◽  
Qifei Guo ◽  
...  
Keyword(s):  
Detection Limit ◽  
Hierarchical Structures ◽  
Glucose Detection ◽  
Good Sensitivity ◽  
Low Detection Limit

An electrode modified with mesoporous Ni0.3Co2.7O4 hierarchical structures shows a low detection limit of 1.0 μM glucose, good sensitivity of 206.5 mA mM−1 cm−2, and good selectivity.

scholarly journals Development of Galactose Biosensor Based on Functionalized ZnO Nanorods with Galactose Oxidase

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
K. Khun ◽  
Z. H. Ibupoto ◽  
O. Nur ◽  
M. Willander
Keyword(s):  
Ascorbic Acid ◽  
Electromotive Force ◽  
Zno Nanorods ◽  
Galactose Oxidase ◽  
Fast Time ◽  
Good Sensitivity ◽  
Magnesium Ions ◽  
Detection Range ◽  
Linear Detection ◽  
Cross Linker

The fabrication of galactose biosensor based on functionalised ZnO nanorods is described. The galactose biosensor was developed by immobilizing galactose oxidase on ZnO nanorods in conjunction with glutaraldehyde as a cross-linker molecule. The IRAS study provided evidence for the interaction of galactose oxidase with the surface of ZnO nanorods. The electromotive force (EMF) response of the galactose biosensor was measured by potentiometric method. We observed that the proposed biosensor has a linear detection range over a concentration range from 10 mM to 200 mM with good sensitivity of89.10±1.23 mV/decade. In addition, the proposed biosensor has shown fast time response of less than 10 s and a good selectivity towards galactose in the presence of common interferents such as ascorbic acid, uric acid, glucose, and magnesium ions. The galactose biosensor based on galactose oxidase immobilized ZnO nanorods has a shelf life more than four weeks.

Ferritin-mediated biomimetic synthesis of bimetallic Au–Ag nanoparticles on graphene nanosheets for electrochemical detection of hydrogen peroxide

2015 ◽  
Vol 08 (04) ◽  
pp. 1550044 ◽  
Author(s):  
Li Wang ◽  
Jiku Wang ◽  
Pengjuan Ni ◽  
Zhuang Li
Keyword(s):  
Hydrogen Peroxide ◽  
Detection Limit ◽  
Green Synthesis ◽  
Electrochemical Detection ◽  
Ag Nanoparticles ◽  
Graphene Nanosheets ◽  
Amperometric Biosensor ◽  
Biomimetic Synthesis ◽  
Detection Range ◽  
Linear Detection

We demonstrated a biomimetic green synthesis of bimetallic Au – Ag nanoparticles (NPs) on graphene nanosheets (GNs). The spherical protein, ferritin ( Fr ), was bound onto GNs and served as the template for the synthesis of GN / Au – Ag nanohybrids. The created GN / Au – Ag nanohybrids were further utilized to fabricate a non-enzymatic amperometric biosensor for the sensitive detection of hydrogen peroxide ( H 2 O 2), and this biosensor displayed high performances to determine H 2 O 2 with a detection limit of 20.0 × 10-6 M and a linear detection range from 2.0 μM to 7.0 mM.

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