scholarly journals Drug induced micelle-to-vesicle transition in aqueous solutions of cationic surfactants

RSC Advances ◽  
2017 ◽  
Vol 7 (7) ◽  
pp. 3861-3869 ◽  
Author(s):  
Zuber S. Vaid ◽  
Arvind Kumar ◽  
Omar A. El Seoud ◽  
Naved I. Malek
Keyword(s):  
Drug Delivery ◽  
Ionic Liquid ◽  
Aqueous Solutions ◽  
Cationic Surfactants ◽  
Cetyltrimethylammonium Bromide ◽  
Diclofenac Sodium ◽  
Drug Induced ◽  
P Solubilization ◽  
Micellar Aggregates ◽  
Potential Use

Solubilization of the drug diclofenac sodium (DS) in micellar aggregates of ionic liquid-based surfactants and cetyltrimethylammonium bromide at 25 °C induces changes to worm-like micelles and vesicles, with potential use in drug delivery.

Nano-Vehicles for Drug Delivery Using Low-Cost Cationic Surfactants: A Drug Induced Structural Transitions

2018 ◽  
Vol 3 (32) ◽  
pp. 9454-9463 ◽  
Author(s):  
Sargam M. Rajput ◽  
Krishnakant Gangele ◽  
Sugam Kumar ◽  
Vinod K Aswal ◽  
Jitendra P. Mata ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cationic Surfactants ◽  
Low Cost ◽  
Structural Transitions ◽  
Drug Induced

scholarly journals Effect of Methanol on Viscosity of Aqueous Solutions of Cationic Surfactants at 298.15 to 323.15 K

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Sujit Kumar Shah ◽  
Sujeet Kumar Chatterjee ◽  
Ajaya Bhattarai
Keyword(s):  
Critical Micelle Concentration ◽  
Aqueous Solutions ◽  
Cationic Surfactants ◽  
Cetyltrimethylammonium Bromide ◽  
Mixed Solvent ◽  
Relative Viscosity ◽  
Dodecyltrimethylammonium Bromide ◽  
Solvent Interactions ◽  
Volume Fractions ◽  
Surfactant Solutions

Viscosity measurements have been made to the solutions of dodecyltrimethylammonium bromide (DTAB) and cetyltrimethylammonium bromide (CTAB) in 0.10, 0.20, 0.30, and 0.40 volume fractions of methanol in methanol-water mixed solvent media at 298.15, 308.15, 318.15, and 323.25 K. Critical micelle concentration (CMC) values have been determined. From relative viscosity for surfactant solutions, related viscosityBcoefficients are calculated and the values are interpreted in terms of solute-solvent interactions.

Potential Use of Nanomedicine for Drug Delivery Across the Blood-Brain Barrier in Healthy and Diseased Brain

2016 ◽  
Vol 15 (9) ◽  
pp. 1079-1091 ◽  
Author(s):  
Barbara Ruozi ◽  
Daniela Belletti ◽  
Francesca Pederzoli ◽  
Flavio Forni ◽  
Maria Angela Vandelli ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Blood Brain ◽  
Potential Use

scholarly journals Extracellular Vesicles-Based Drug Delivery Systems: A New Challenge and the Exemplum of Malignant Pleural Mesothelioma

2020 ◽  
Vol 21 (15) ◽  
pp. 5432 ◽  
Author(s):  
Stefano Burgio ◽  
Leila Noori ◽  
Antonella Marino Gammazza ◽  
Claudia Campanella ◽  
Mariantonia Logozzi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Early Diagnosis ◽  
Extracellular Vesicles ◽  
Delivery System ◽  
Malignant Pleural Mesothelioma ◽  
Cell Communication ◽  
Cell Types ◽  
Delivery Systems ◽  
Pleural Mesothelioma ◽  
Potential Use

Research for the most selective drug delivery to tumors represents a fascinating key target in science. Alongside the artificial delivery systems identified in the last decades (e.g., liposomes), a family of natural extracellular vesicles (EVs) has gained increasing focus for their potential use in delivering anticancer compounds. EVs are released by all cell types to mediate cell-to-cell communication both at the paracrine and the systemic levels, suggesting a role for them as an ideal nano-delivery system. Malignant pleural mesothelioma (MPM) stands out among currently untreatable tumors, also due to the difficulties in achieving an early diagnosis. Thus, early diagnosis and treatment of MPM are both unmet clinical needs. This review looks at indirect and direct evidence that EVs may represent both a new tool for allowing an early diagnosis of MPM and a potential new delivery system for more efficient therapeutic strategies. Since MPM is a relatively rare malignant tumor and preclinical MPM models developed to date are very few and not reliable, this review will report data obtained in other tumor types, suggesting the potential use of EVs in mesothelioma patients as well.

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