A pre-column derivatization method allowing quantitative metabolite profiling of carboxyl and phenolic hydroxyl group containing pharmaceuticals in human plasma via liquid chromatography-inductively coupled plasma-tandem mass spectrometry (LC-ICP-MS/MS)

2018 ◽  
Vol 33 (2) ◽  
pp. 274-282 ◽  
Author(s):  
Sanwang Li ◽  
Balázs Klencsár ◽  
Lieve Balcaen ◽  
Filip Cuyckens ◽  
Frederic Lynen ◽  
...  

Novel analytical strategies for investigating drug ADME (absorption, distribution, metabolism and excretion).

2019 ◽  
Vol 34 (7) ◽  
pp. 1433-1438 ◽  
Author(s):  
Jenny Nelson ◽  
Laura Poirier ◽  
Francisco Lopez-Linares

The potential of using inductively coupled plasma tandem mass spectrometry, ICP-MS/MS, (also known as triple quadrupole ICP-MS) for the determination of chloride in petroleum crude samples following direct dilution was investigated.


2014 ◽  
Vol 6 (13) ◽  
pp. 4516-4520 ◽  
Author(s):  
Renata S. Amais ◽  
Clarice D. B. Amaral ◽  
Lucimar L. Fialho ◽  
Daniela Schiavo ◽  
Joaquim A. Nóbrega

The feasibility of inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) to overcome polyatomic interferents in severely affected isotope determination is demonstrated here.


2016 ◽  
Vol 10 (4) ◽  
pp. 992-998 ◽  
Author(s):  
Fernanda C. Pinheiro ◽  
Clarice D. B. Amaral ◽  
Daniela Schiavo ◽  
Joaquim A. Nóbrega

Author(s):  
Stefano Bertinetti ◽  
Eduardo Bolea-Fernandez ◽  
Mery Malandrino ◽  
Beatrice Moroni ◽  
David Cappelletti ◽  
...  

In this work, a new method has been developed for accurate and precise Sr isotopic analysis of microsamples via inductively coupled plasma - tandem mass spectrometry (ICP-MS/MS). For introduction of...


2015 ◽  
Vol 30 (8) ◽  
pp. 1799-1808 ◽  
Author(s):  
Jason D. Palcic ◽  
Janet S. Jones ◽  
E. Lindsay Flagg ◽  
Stephen F. Donovan

A simple and robust LC-ICP-MS/MS method is described for quantitative analysis of human urine for (2-chlorovinyl)arsonic acid (CVAOA), a metabolite of Lewisite.


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