The effect of anthracene-based chalcone derivatives in the resazurin dye reduction assay mechanisms for the investigation of Gram-positive and Gram-negative bacterial and fungal infection

2018 ◽  
Vol 42 (2) ◽  
pp. 1037-1045 ◽  
Author(s):  
Gopi Prakash ◽  
Mani Boopathy ◽  
Ramasamy Selvam ◽  
Samuel Johnsanthosh Kumar ◽  
Kathavarayan Subramanian
Keyword(s):  
Fungal Infection ◽  
Gram Positive ◽  
Gram Negative ◽  
Antifungal Activities ◽  
Chalcone Derivatives ◽  
Antibacterial And Antifungal Activities ◽  
Reduction Assay ◽  
Dye Reduction ◽  
Antibacterial And Antifungal ◽  
Resazurin Dye

A novel series of anthracene-based chalcone derivatives were synthesized and evaluated in terms of their antibacterial and antifungal activities.

scholarly journals Screening of various solvents and extracts of Achillea latiloba Ledeb. ex Nordm for antibacterial and antifungal activities

2014 ◽  
Vol 60 (2) ◽  
pp. 29-40 ◽  
Author(s):  
Ömer Ertürk
Keyword(s):  
Streptococcus Mutans ◽  
Salmonella Enteritidis ◽  
Dilution Method ◽  
Agar Dilution Method ◽  
Gram Positive ◽  
Gram Negative ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal

Abstract In this study the antibacterial and antifungal activities of extracted Achillea latiloba Ledeb. ex Nordm (Asteraceae) samples in acetone, ethyl acetate, ethanol, methanol and dimethyl sulfoxide (DMSO) from Trabzon Province (Turkey) were investigated. Antimicrobial activity of A. latiloba varied depending on the extract of samples, dosage of extracts, and the extraction solvents for all test microorganisms. Staphylococcus aureus, Streptococcus salivarius, Klebsiella pneumoniae, Escherichia coli, Salmonella enteritidis, Streptococcus pneumoniae, Bacillus cereus, Listeria monocytogenes, Streptococcus mutans, Pseudomonas aeruginosa, Bacillus licheniformis, Micrococcus luteus, Bacillus subtillis, Proteus vulgaris and Candida albicans were studied with use of disc diffusion and agar dilution method. The results indicated that each of the crude extracts of Achillea latiloba exhibited a more or less pronounced antibacterial and antifungal potency both in Gram-positive and Gram-negative bacteria and fungi. While in the Gram-negative group, the most sensitive microorganism to Achillea latiloba were S. enteritidis and Streptococcus mutans which is Gram-positive. In the Gram-positive group, the microorganisms most sensitive to Achillea latiloba were Streptococcus mutans and L. monocytogenes. However, the least sensitive microorganism was P. vulgaris. The results presented in this paper suggest that Achillea latiloba possesses additional antimicrobial activities that has an effect against some Gram-negative, Gram-positive bacteria and fungi.

scholarly journals Antibacterial and Antifungal Activities of Rumex Confertus Willd

2021 ◽  
Vol 9 (12) ◽  
pp. 855-856
Author(s):  
G. D. Shermatova
Keyword(s):  
Antibacterial Activity ◽  
Ethyl Acetate ◽  
Gram Positive ◽  
Antifungal Activities ◽  
Gram Positive Bacteria ◽  
Root Part ◽  
Fungal Activity ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

Abstract: The leaves and roots of Rumex confertus Willd were tested in vitro for antibacterial and fungal activity in the fractions of gasoline, chloroform, ethyl acetate and butanol. As a result, it was found that the leaves of the Rumex confertus Willd plant, chloroform and ethyl acetate fractions of the root part have antibacterial activity against fungi and gram-positive bacteria. Keywords: Rumex confertus Willd, fractions, extracts, antibacterial, antifungal

Synthesis, antibacterial, and antifungal activities of new pyrimidinone derivatives

2015 ◽  
Vol 21 (4) ◽  
pp. 191-194 ◽  
Author(s):  
Oussama Cherif ◽  
Fatma Masmoudi ◽  
Fatma Allouche ◽  
Fakher Chabchoub ◽  
Mohamed Trigui
Keyword(s):  
Antimicrobial Activity ◽  
Broad Spectrum ◽  
Pathogenic Fungi ◽  
Gram Negative Bacteria ◽  
Efficient Synthesis ◽  
Gram Negative ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal

AbstractAn efficient synthesis of new pyrrolopyrimidinones 3a-d and isoxazolopyrimidinones 4a-c from the respective aminocyanopyrroles 1a-d and aminocyanoisoxazoles 2a-c is presented. The synthesized compounds were screened for antimicrobial activity against a panel of bacteria and fungi. Compound 4c exhibits remarkable activity against a broad spectrum of Gram-positive and Gram-negative bacteria and pathogenic fungi.

scholarly journals Study of the antibacterial and antifungal activities of synthetic benzyl bromides, ketones, and corresponding chalcone derivatives

2016 ◽  
Vol Volume 10 ◽  
pp. 3653-3660 ◽  
Author(s):  
Muhamad Ali Shakhatreh ◽  
Mousa L. Al-Smadi ◽  
Omar F. Khabour ◽  
Fatima A. Shuaibu ◽  
Emad I. Hussein ◽  
...  
Keyword(s):  
Antifungal Activities ◽  
Chalcone Derivatives ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

scholarly journals Biological Activity of Phenothiazine Sulfonamides

2019 ◽  
Vol 8 (2S6) ◽  
pp. 535-537
Keyword(s):  
Rhizopus Oryzae ◽  
Antibacterial Activities ◽  
Bacillus Sphaericus ◽  
Dilution Method ◽  
Curvularia Lunata ◽  
Gram Negative ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

Background: Antibacterial activities in “dimethylsulfoxide (DMSO)” were executed by the broth dilution method utilizing nutrient agar. By using the agar cup bioassay method antifungal activities were calculated with “Clotrimazole” as the standard. The novel compounds 1a-j have been evaluated in vitro for their antibacterial activity by “Gram-positive bacteria namely Bacillus subtilis, Bacillus sphaericus and Staphylococcus aureus and three Gram-negative bacteria Pseudomonas aeruginosa”, “Klebsiella aerogenes and Chromobacterium violaceum”. All ten compounds were analysed for their antifungal activity against five test “organisms Aspergillus niger, Chrysosporium tropicum, Rhizopus oryzae, Fusarium moniliforme and Curvularia lunata”. Among the isolated compounds 1d and 1e evinced dynamic Movement towards both gram certain What's more gram negative microscopic organisms. Mixes 1d Also 1f uncovered useful antifungal action. All the secluded compounds were scrutinized for their antibacterial and antifungal activities and most of the compounds manifested remarkable anti bacterial and anti fungal activity.

Synthesis and Biological Evaluation of some Novel Pyrano[2,3-d]Pyrimidine Derivatives

2017 ◽  
Vol 74 ◽  
pp. 9-14
Author(s):  
Pratik K. Talpara ◽  
Guarang G. Dubal ◽  
Viresh H. Shah
Keyword(s):  
Biological Evaluation ◽  
Alder Reaction ◽  
Gram Negative Bacteria ◽  
Pyrimidine Derivatives ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

The synthesis of novel Pyrano[2,3-d]pyrimidine derivatives, had been synthesized by three component domino Knoevenagel hetero Diels-Alder reaction. The products were assayed for their in vitro biological assay antibacterial activity against with two Gram-positive bacteria Staphylococcus aureus MTCC-96, Streptococcus pyogenes MTCC 443, two Gram-negative bacteria Escherichia coli MTCC 442, Pseudomonas aeruginosa MTCC 441 and three fungal strains Candida albicans MTCC 227, Aspergillus Niger MTCC 282, Aspergillus clavatus MTCC 1323 taking ampicillin, chloramphenicol, ciprofloxacin, norfloxacin, nystatin, and griseofulvin as standard drugs. Among the various synthesized heterocyclic compounds, 1b, 1c and 1g are display broad spectrum antibacterial and antifungal activities against both gram-positive and gram-negative bacteria as compared with standard drugs.

scholarly journals Conventional and Microwave Irradiated Syntheses of New Symmetric Double Schiff Bases of 1,1’-Bis(4-Amino Phenyl)Cyclohexane, their Spectral Characterization and Microbial Activity

2015 ◽  
Vol 58 ◽  
pp. 33-39 ◽  
Author(s):  
Bhavesh J. Gangani ◽  
Parsotam H. Parsania
Keyword(s):  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Green Chemistry ◽  
Microbial Activity ◽  
Schiff Bases ◽  
Spectral Characterization ◽  
Gram Negative ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

Symmetric double Schiff bases of 1,1’- bis (4-amino phenyl) cyclohexane and substituted aromatic benzaldehydes were synthesized by thermal and microwave irradiated green chemistry techniques. The purity of Schiff bases was checked by TLC. The structure of Schiff bases were supported by UV, FTIR, 1HNMR and MS techniques. The antibacterial and antifungal activities of Schiff bases were checked against gram positive and gram negative microbes. Schiff bases showed moderate antibacterial activity but they showed good comparable antifungal activity against chosen microbes and standard drugs.

scholarly journals Chemical Composition and Antimicrobial Activity of the Essential Oil from Flowers of Eryngium triquetrum (Apiaceae) Collected Wild in Sicily

2016 ◽  
Vol 11 (7) ◽  
pp. 1934578X1601100
Author(s):  
Simona Casiglia ◽  
Maurizio Bruno ◽  
Sergio Rosselli ◽  
Felice Senatore
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Art Works ◽  
Main Components ◽  
Antibacterial And Antifungal ◽  
Historical Art

The chemical composition of the essential oil from flowers of Eringium triquetrum Vahl. collected in Sicily was evaluated by GC and GC-MS. The main components were pulegone (50.6%), piperitenone (30.5%) and menthone (7.0%). Comparison of this oil with other studied oils of Eringium species is discussed. The oil showed good antibacterial and antifungal activities against some microorganisms that infest historical art works.

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