Synthesis, antibacterial, and antifungal activities of new pyrimidinone derivatives
Keyword(s):
AbstractAn efficient synthesis of new pyrrolopyrimidinones 3a-d and isoxazolopyrimidinones 4a-c from the respective aminocyanopyrroles 1a-d and aminocyanoisoxazoles 2a-c is presented. The synthesized compounds were screened for antimicrobial activity against a panel of bacteria and fungi. Compound 4c exhibits remarkable activity against a broad spectrum of Gram-positive and Gram-negative bacteria and pathogenic fungi.
2015 ◽
Vol 11
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pp. 869-874
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2016 ◽
Vol 65
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pp. 11-26
2018 ◽
Vol 16
(32)
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pp. 5764-5770
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2016 ◽
Vol 11
(7)
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pp. 1934578X1601100