Genipin-crosslinked adipose stem cell derived extracellular matrix-nano graphene oxide composite sponge for skin tissue engineering

2018 ◽  
Vol 6 (6) ◽  
pp. 979-990 ◽  
Author(s):  
Batzaya Nyambat ◽  
Chih-Hwa Chen ◽  
Pei-Chun Wong ◽  
Chih-Wei Chiang ◽  
Mantosh Kumar Satapathy ◽  
...  
Keyword(s):  
Mechanical Property ◽  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Graphene Oxide ◽  
Stem Cell ◽  
Adipose Stem Cell ◽  
High Mechanical Property ◽  
Skin Tissue Engineering ◽  
Oxide Composite ◽  
Nano Graphene

3D Bioscaffold with relative high mechanical property was developed using rabbit ADSCs.

Effects of Cyclic Tensioning Duration on the Mechanical Property of a Stem Cell-Based Self-Assembled Tissue (scSAT) Derived From Synovium

2009 ◽  
Author(s):  
Kei Saito ◽  
Atsushi Ogawa ◽  
Wataru Ando ◽  
Norimasa Nakamura ◽  
Hiromichi Fujie
Keyword(s):  
Mechanical Property ◽  
Tissue Engineering ◽  
Stem Cells ◽  
Extracellular Matrix ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Static Loads ◽  
Self Assembled ◽  
Fibrous Tissues ◽  
Bio Synthesis

Various fibrous tissues such as tendons and ligaments functionally adapt to dynamic and static loads. Although a variety of biomechanical studies have been performed so far to determine the mechanism of remodelling in fibrous tissues, it was difficult to obtain detailed information because of complicated constitution of the tissues. Meanwhile we have been developing a stem cell-based self-assembled tissue (scSAT) for tissue engineering, composed of synovial-derived mesenchymal stem cells (MSCs) and their native extracellular matrix. The scSAT used for cartilage repair is called tissue engineered construct (TEC) [1, 2]. Since the scSAT specimen is consisted of stem cells and their native extracellular matrix, it can be a good experimental model of fibrous tissues to determine the process of remodelling. Therefore, the effects of cyclic tensioning and its duration on the mechanical property of the scSAT specimen were investigated in the present study. It was also the purpose of the present study to determine the bio-synthesis condition adequate for improving the mechanical property of the scSAT specimen.

scholarly journals Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Azar Nourian Dehkordi ◽  
Fatemeh Mirahmadi Babaheydari ◽  
Mohammad Chehelgerdi ◽  
Shiva Raeisi Dehkordi
Keyword(s):  
Tissue Engineering ◽  
Wound Healing ◽  
Stem Cell ◽  
Therapeutic Strategies ◽  
Skin Tissue ◽  
Skin Tissue Engineering

Application of marrow mesenchymal stem cell-derived extracellular matrix in peripheral nerve tissue engineering

2016 ◽  
Vol 11 (8) ◽  
pp. 2250-2260 ◽  
Author(s):  
Yun Gu ◽  
Zhenmeiyu Li ◽  
Jing Huang ◽  
Hongkui Wang ◽  
Xiaosong Gu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Peripheral Nerve ◽  
Nerve Tissue ◽  
Nerve Tissue Engineering

Electrospinning adipose tissue-derived extracellular matrix for adipose stem cell culture

2012 ◽  
Vol 100A (7) ◽  
pp. 1716-1724 ◽  
Author(s):  
Michael P. Francis ◽  
Patrick C. Sachs ◽  
Parthasarathy A. Madurantakam ◽  
Scott A. Sell ◽  
Lynne W. Elmore ◽  
...  
Keyword(s):  
Cell Culture ◽  
Extracellular Matrix ◽  
Adipose Tissue ◽  
Stem Cell ◽  
Adipose Stem Cell ◽  
Stem Cell Culture

Curcumin loaded nano graphene oxide reinforced fish scale collagen – a 3D scaffold biomaterial for wound healing applications

RSC Advances ◽  
2015 ◽  
Vol 5 (119) ◽  
pp. 98653-98665 ◽  
Author(s):  
Tapas Mitra ◽  
Piyali Jana Manna ◽  
S. T. K. Raja ◽  
A. Gnanamani ◽  
P. P. Kundu
Keyword(s):  
Tissue Engineering ◽  
Wound Healing ◽  
Graphene Oxide ◽  
Type I Collagen ◽  
Type I ◽  
Fish Scale ◽  
3D Scaffold ◽  
Engineering Research ◽  
Nano Graphene ◽  
Tissue Engineering Research

We prepare a highly stabilized nano graphene oxide functionalized with type I collagen to make a 3D scaffold as a novel platform for better tissue engineering research..

scholarly journals Etched 3D-Printed Polycaprolactone Constructs Functionalized with Reduced Graphene Oxide for Enhanced Attachment of Dental Pulp-Derived Stem Cells

Pharmaceutics ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2146
Author(s):  
Austin J. Bow ◽  
Thomas J. Masi ◽  
Madhu S. Dhar
Keyword(s):  
Tissue Engineering ◽  
Graphene Oxide ◽  
Stem Cell ◽  
Reduced Graphene Oxide ◽  
Dental Pulp ◽  
Fluorescent Protein ◽  
Acetic Acid Solution ◽  
Cell Populations ◽  
Reduced Graphene

A core challenge in the field of tissue engineering is the ability to establish pipeline workflows for the design and characterization of scaffold technologies with clinically translatable attributes. The parallel development of biomaterials and stem cell populations represents a self-sufficient and streamlined approach for establishing such a pipeline. In the current study, rat dental pulp stem cell (rDPSC) populations were established to assess functionalized polycaprolactone (PCL) constructs. Initial optimization and characterization of rDPSC extraction and culture conditions confirmed that cell populations were readily expandable and demonstrated surface markers associated with multi-potency. Subset populations were transduced to express DsRed fluorescent protein as a mechanism of tracking both cells and cell-derived extracellular matrix content on complex scaffold architecture. Thermoplastic constructs included reduced graphene oxide (rGO) as an additive to promote cellular attachment and were further modified by surface etching a weak acetic acid solution to roughen surface topographical features, which was observed to dramatically improve cell surface coverage in vitro. Based on these data, the modified rGO-functionalized PCL constructs represent a versatile platform for bone tissue engineering, capable of being applied as a standalone matrix or in conjunction with bio-active payloads such as DPSCs or other bio-inks.

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