:
Phytocompounds isolated from plants are well appraised for their broad pharmacological propensities in several
pathologies. One key benefit of phytoconstituents is their relatively low toxicity and adverse effects. Nonetheless, poor
solubility, permeation, and poor specificity at the target site tend to hinder its therapeutic efficacy. Hence, novel technologies
for drug delivery systems are being developed via the use of various nanoformulation strategies to overcome these
challenges and give uniform medication focusing at the dynamic site in desired concentration and improved therapeutic
efficacy. Such approaches comprise of novel drug delivery systems (NDDS). The utilisation of herbal formulations for
NDDS is more beneficious and advantageous as opposed to others. The utilisation of ethosome, liposome, emulsion,
phytosomes, microsphere, and strong lipid nanoparticles of herbal formulation have improved the remedial impacts of plant
extricates. With the utilisation of all these, directed delivery of the formulation is accomplished, because of which the
formulation exhibits impact on the site, and the bioavailability of the formulation is likewise expanded. With these novel
medication conveyance frameworks, the actives and concentrates which are utilised as part of natural formulations exhibit
sustained release of formulation, enhancement in stability, improved therapeutic efficacy, and protection from toxicity. The
primary motivation behind creating alternative drug delivery technologies is to expand the effectiveness of drug conveyance
and safety in the process of drug conveyance and give more comfort to the patient. In this review, the importance of various
phytocompounds in the delivery of drugs are highlighted as well as their importance in reducing the risk or diseases.