scholarly journals Construction of a lysosome-targetable ratiometric fluorescent probe for H2O2 tracing and imaging in living cells and an inflamed model

RSC Advances ◽  
2021 ◽  
Vol 11 (39) ◽  
pp. 24032-24037
Author(s):  
Rongrong Zhou ◽  
Qiyao Peng ◽  
Dan Wan ◽  
Chao Yu ◽  
Yuan Zhang ◽  
...  

Hydrogen peroxide (H2O2), an important reactive oxygen species (ROS) with unique destructive oxidation properties, can be produced in lysosomes to fight off pathogens.

RSC Advances ◽  
2019 ◽  
Vol 9 (67) ◽  
pp. 39532-39535
Author(s):  
Linan Hu ◽  
Jiayi Liu ◽  
Jie Zhang ◽  
Hailiang Zhang ◽  
Pengfei Xu ◽  
...  

A new ratiometric fluorescent probe JNY-1 for sensitive detection of H2O2 is presented with selectivity over other reactive oxygen species, reactive nitrogen species, and biologically relevant species. Imaging of H2O2 in liver cancer HepG2 cells was achieved.


Author(s):  
Qian Wu ◽  
Youmei Li ◽  
Ying Li ◽  
Dong Wang ◽  
Ben Zhong Tang

Hydrogen peroxide (H2O2), as one kind of key reactive oxygen species (ROS), is mainly produced endogenously primarily in the mitochondria. The selective monitoring of H2O2 in living cells is of...


2012 ◽  
Vol 48 (39) ◽  
pp. 4719 ◽  
Author(s):  
Manoj Kumar ◽  
Naresh Kumar ◽  
Vandana Bhalla ◽  
Parduman Raj Sharma ◽  
Yasrib Qurishi

2013 ◽  
Vol 295-298 ◽  
pp. 475-478 ◽  
Author(s):  
Zhi Xiang Han ◽  
Ming Hui Du ◽  
Guo Xi Liang ◽  
Xiang Yang Wu

Rhodamine B thiohydrazide (RBS) was firstly employed as turn-on fluorescent probe for hypochlorite in aqueous solution and living cells. It exhibits a stable response to hypochlorite from 1.0×10-6to 1.0×10-5M with a detection limit of 3.3×10-7M. The response of this probe to hypochlorite is fast and highly selective compared with other reactive oxygen species (such as.OH,1O2, H2O2) and other common anions (such as X-, ClO2-, ClO4-, NO3-, NO2-, OH-, Ac-, CO32-, SO42-).


The Analyst ◽  
2021 ◽  
Author(s):  
Fangyun Xin ◽  
Jiwei Zhao ◽  
Wei Shu ◽  
Xiaoling Zhang ◽  
Xixian Luo ◽  
...  

Peroxynitrite (ONOO‒), a highly reactive oxygen species (ROS), is implicated with many physiological and pathological processes including cancer, neurodegenerative diseases and inflammation. In this regard, developing effective tools for highly...


The Analyst ◽  
2020 ◽  
Vol 145 (3) ◽  
pp. 939-945 ◽  
Author(s):  
Yuanyuan Zhang ◽  
Yufan Ma ◽  
Zhuo Wang ◽  
Xueyan Zhang ◽  
Xin Chen ◽  
...  

Hypochlorous acid (HOCl)/hypochlorite (OCl−), an important reactive oxygen species, plays a number of important roles in various physiological processes.


2021 ◽  
Vol 13 (14) ◽  
pp. 1715-1719
Author(s):  
Dingyi Guo ◽  
Jie Sun ◽  
Minggang Tian ◽  
Weiying Lin

A fluorescent probe for reversibly monitoring mitochondrial membrane potential in living cells has been constructed successfully, which could be employed to visualize cell damage by reactive oxygen species.


2021 ◽  
Author(s):  
Chunning Sun ◽  
Michael Gradzielski

Hydrogen peroxide (H2O2), a key reactive oxygen species, plays an important role in living organisms, industrial and environmental fields. Here, a non-contact upconversion nanosystem based on the excitation energy attenuation...


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