Migraine and Menstruation: A Pilot Study

Cephalalgia ◽  
1990 ◽  
Vol 10 (6) ◽  
pp. 305-310 ◽  
Author(s):  
EA MacGregor ◽  
H Chia ◽  
RC Vohrah ◽  
M Wilkinson
Keyword(s):  
Pilot Study ◽  
Menstrual Cycle ◽  
Hormonal Therapy ◽  
Migraine Without Aura ◽  
Hormonal Treatment ◽  
Menstrual Migraine ◽  
Menstrual Cycles ◽  
Menstrually Related Migraine ◽  
City Of London ◽  
The City

Objective: To define the term “menstrual” migraine and to determine the prevalence of “menstrual” migraine in women attending the City of London Migraine Clinic. Design: Women attending the clinic were asked to keep a record of their migraine attacks and menstrual periods for at least 3 complete menstrual cycles. Results: Fifty-five women completed the study. “Menstrual” migraine was defined as “migraine attacks which occur regularly on or between days -2 to +3 of the menstrual cycle and at no other time”. Using this criterion, 4 (7.2%) of the women in our population had “menstrual” migraine. All 4 women had migraine without aura. A further 19 (34.5%) had an increased number of attacks at the time of menstruation in addition to attacks at other times of the cycle. Eighteen (32.7%) had attacks occurring throughout the cycle but with no increase in number at the time of menstruation. Fourteen (25.5%) had no attacks within the defined period during the 3 cycles studied. Discussion: A small percentage of women have attacks only occurring at the time of menstruation, which can he defined as true “menstrual” migraine. This group is most likely to respond to hormonal treatment. The group of 34.5% who have an increased number of attacks at the time of menstruation in addition to attacks at other times of the month could be defined as having “menstrually related” migraine and might well respond to hormonal therapy. The 32.7% who have attacks throughout the menstrual cycle without an increase at menstruation are unlikely to respond to hormonal therapy. The 25.5% who do not have attacks related to menstruation almost certainly will not respond to hormonal therapy.

The Association of Menstrual Migraine with the Premenstrual Syndrome

Cephalalgia ◽  
1993 ◽  
Vol 13 (6) ◽  
pp. 422-425 ◽  
Author(s):  
F Facchinetti ◽  
I Neri ◽  
E Martignoni ◽  
L Fioroni ◽  
G Nappi ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Negative Affect ◽  
Diagnostic Criteria ◽  
Patient Group ◽  
Premenstrual Syndrome ◽  
Migraine Without Aura ◽  
Menstrual Migraine ◽  
Menstrual Cycles ◽  
Menstrual Distress

To investigate the comorbidity of premenstrual syndrome (PMS) and menstrual migraine, the Menstrual Distress Questionnaire (MDQ) was prospectively administered for two consecutive menstrual cycles to 22 patients with menstrual migraine, 12 cases with migraine without aura and 15 patients with PMS. MDQ scores varied throughout the menstrual cycle in each patient group, the wider changes being shown by patients with PMS. Fourteen menstrual migraine patients and 4 migraine without aura patients achieved diagnostic criteria for PMS over two menstrual cycles. In these patients MDQ scores did not differ from PMS sufferers at any stage of the menstrual cycle. The premenstrual increase of each cluster of PMS symptoms was identical in menstrual migraine and PMS subjects with the exception of negative affect. We suggest that PMS symptoms should be taken into account in the IHS diagnostic criteria for menstrual migraine.

Headache

2017 ◽  
Author(s):  
Regina Krel ◽  
Paul G. Mathew
Keyword(s):  
Menstrual Cycle ◽  
Chief Complaint ◽  
Menstrual Migraine ◽  
Clinical Implications ◽  
Menstrually Related Migraine ◽  
Neurology Clinic ◽  
Gender Specific ◽  
Insight Into ◽  
Pure Menstrual Migraine

Migraine is a common disorder that affects women of menstruating age, and it is frequently the chief complaint of women presenting in the neurology clinic. The prevalence of menstrually related migraine can range from 20–60%, while pure menstrual migraine occurs in less than 10% of women. In addition to utilizing non–gender-specific abortive and preventative strategies, understanding migraine and its relationship to hormones, particularly estrogen, can have clinical implications for optimal treatment. This chapter seeks to provide insight into diagnosing menstrually related migraine, the role of decreased estrogen just prior to menstrual cycle onset and migraine, as well as the therapeutic options that are available to treat and possibly prevent menstrual migraine attacks.

Lack of Seasonal Variation in Menstrually-Related Migraine

Cephalalgia ◽  
2008 ◽  
Vol 28 (12) ◽  
pp. 1277-1281 ◽  
Author(s):  
SI Bekkelund ◽  
KB Alstadhaug ◽  
R Salvesen
Keyword(s):  
Seasonal Variation ◽  
Migraine Headache ◽  
Migraine Without Aura ◽  
Telephone Interview ◽  
Menstrual Migraine ◽  
Menstrually Related Migraine ◽  
Headache Diary ◽  
June July ◽  
Arctic Area ◽  
North Norway

The aim of the study was to study seasonal variation in migraine headache in a group of women with menstrually-related migraine (MRM) compared with non-menstrual migraine. Via newspaper advertisement, women with migraine living in North Norway were invited. The patients were included by questionnaire and telephone interview. We prospectively recorded migraine attacks from a 12-month headache diary performed by a group of 62 women with a mean age of 36.0 years (range 16-46 years), who fulfilled the criteria of migraine without aura. Of these, 29 had MRM and 33 non-menstrual migraine. Mean ratio between number of attacks in the light arctic season (May-June-July) divided with total number of migraine attacks during 12 months was 0.24 (9.4/38.4) in the group of MRM compared with 0.25 (5.6/22.1) in others (confidence interval -4.2, 6.3, P = 0.84). Nor were there more migraine attacks in the dark season in an arctic area (November-December-January) in any group. We found a higher migraine attack rate in those with MRM, but no indication of more or less frequency of attacks during the bright arctic season. These findings support the assumption that MRM and seasonal variation of migraine are due to different mechanisms.

Perfusion Changes with Photic Stimulation During two Phases of the Menstrual Cycle: A Pilot Study Comparing Controls and True Menstrual Migraine Patients

Cephalalgia ◽  
2003 ◽  
Vol 23 (9) ◽  
pp. 907-913 ◽  
Author(s):  
BM Ances ◽  
JA Detre
Keyword(s):  
Pilot Study ◽  
Menstrual Cycle ◽  
Repeated Measures ◽  
Visual Stimulation ◽  
Occipital Lobe ◽  
Menstrual Migraine ◽  
Phase Changes ◽  
Photic Stimulation ◽  
Cycle Phase ◽  
Significant Difference

This pilot study investigated the effect of menstrual cycle phase (late luteal and mid-follicular) on cerebral perfusion changes during photic stimulation in both controls ( n = 5) and true menstrual migraine patients ( n = 5). No significant differences in resting baseline perfusion were observed between the two groups during either phase of the menstrual cycle. During the late luteal phase, changes in perfusion within the occipital lobe due to photic stimulation were similar for both groups. However, during the mid-follicular phase, occipital perfusion during visual stimulation decreased for controls but significantly increased for true menstrual migraine patients ( P < 0.05). A two way repeated measures ANOVA also demonstrated a significant difference between menstrual migraine patients and controls for photic activation ( P < 0.05).

scholarly journals Menstrual versus non-menstrual attacks of migraine without aura in women with and without menstrual migraine

Cephalalgia ◽  
2015 ◽  
Vol 35 (14) ◽  
pp. 1261-1268 ◽  
Author(s):  
Kjersti Grøtta Vetvik ◽  
Jūratė Šaltytė Benth ◽  
E Anne MacGregor ◽  
Christofer Lundqvist ◽  
Michael Bjørn Russell
Keyword(s):  
General Population ◽  
Migraine Without Aura ◽  
Clinical Characteristics ◽  
Repeated Measurements ◽  
Menstrual Migraine ◽  
Headache Disorders ◽  
Severe Nausea ◽  
Menstrual Cycles ◽  
Headache Diary

Objective The objective of this article is to compare clinical characteristics of menstrual and non-menstrual attacks of migraine without aura (MO), prospectively recorded in a headache diary, by women with and without a diagnosis of menstrual migraine without aura (MM) according to the International Classification of Headache Disorders (ICHD). Material and methods A total of 237 women from the general population with self-reported migraine in ≥50% of their menstrual periods were interviewed and classified by a physician according to the criteria of the ICHD II. Subsequently, all participants were instructed to complete a prospective headache diary for at least three menstrual cycles. Clinical characteristics of menstrual and non-menstrual attacks of MO were compared by a regression model for repeated measurements. Results In total, 123 (52%) women completed the diary. In the 56 women who were prospectively diagnosed with MM by diary, the menstrual MO-attacks were longer (on average 10.65 hours, 99% CI 3.17–18.12) and more frequently accompanied by severe nausea (OR 2.14, 99% CI 1.20–3.84) than non-menstrual MO-attacks. No significant differences between menstrual and non-menstrual MO-attacks were found among women with MO, but no MM. Conclusion In women from the general population, menstrual MO-attacks differ from non-menstrual attacks only in women who fulfil the ICHD criteria for MM.

scholarly journals Migraine Associated with Menstruation An Overlooked Trigger

2021 ◽  
Vol 59 (238) ◽  
Author(s):  
Ashlesha Chaudhary
Keyword(s):  
Menstrual Cycle ◽  
Significant Role ◽  
Treatment Method ◽  
Menstrual Migraine ◽  
Menstrual Cycles ◽  
Estrogen Withdrawal ◽  
Hormonal Fluctuations

Menstrual migraine is a condition in females, where headaches are linked with menstruation and may be debilitating. Hormonal fluctuations could have a key role in migraine etiopathogenesis, as several women experience that their migraine attacks correlate with their menstrual cycle. Estrogen withdrawal appears to have a significant role in migraine associated with menstrual cycles, despite the fact that its pathophysiology is not well known. The treatment method can also vary from that used to treat nonmenstrual migraines. However, with proper identification and management of the condition, it can be bearable. This article highlights some portions of what is known about migraine, its triggers including the experience of a sufferer and aims to provide readers with a better understanding of migraine in women by understanding these aspects of the condition.

scholarly journals Menstrual Migraine : How Hormones Impact Migraine

2021 ◽  
Vol 5 (1) ◽  
pp. 9-17
Author(s):  
Restu Susanti ◽  
Syamel Muhammad
Keyword(s):  
Menstrual Cycle ◽  
Trigeminal Nerve ◽  
Menstrual Migraine ◽  
Menstrually Related Migraine ◽  
Female Hormones

Menstrual Migraine is divided into 2 subtypes: Menstrually Related Migraine (MRM) and Pure Menstrual Migraines (PMM). In PMM symptoms do not occur outside the menstrual cycle while MRM, symptoms can occur at other times apart from the menstrual cycle. The occurrence of menstrual migraines is related to the female hormones cycle in the form of the decrease in estrogen levels which usually occurs a week before the onset of menstruation. The mechanism is unclear, but it is thought that a decrease in estrogen levels can trigger decrease in serotonin levels, causing cranial vasodilation and sensitization of the trigeminal nerve.  Keywords: menstrual migraine, hormones

scholarly journals Correlation between circulating leptin and luteinizing hormone during the menstrual cycle in normal-weight women

1998 ◽  
pp. 190-194 ◽  
Author(s):  
T Teirmaa ◽  
V Luukkaa ◽  
J Rouru ◽  
M Koulu ◽  
R Huupponen
Keyword(s):  
Menstrual Cycle ◽  
Luteinizing Hormone ◽  
Young Women ◽  
Hormonal Therapy ◽  
Normal Weight ◽  
Reproductive Hormones ◽  
Major Influence ◽  
Serum Leptin ◽  
Menstrual Cycles ◽  
Significant Difference

OBJECTIVE: Leptin is the hormonal product of the ob gene. It is expressed in adipocytes and participates in the regulation of food intake and metabolism. Since leptin also seems to signal metabolic information to the reproductive system, we studied the association between reproductive hormones and plasma leptin in normal-weight young women. DESIGN: Eight young women with normal menstrual cycles (body mass index (BMI) 21.2 +/- 1.6 kg/m2) and eight young women using hormonal contraception (BMI 21.4 +/- 1.1 kg/m2) were studied. Furthermore, six women with normal menstrual cycles and no hormonal therapy (BMI 20.7 +/- 1.2 kg/m2) were studied around the time of the anticipated ovulation. METHODS: Serum leptin, estradiol, progesterone and luteinizing hormone (LH) concentrations were measured with radioimmunoassays. RESULTS: Serum leptin concentrations were similar at the beginning of the cycle, at the time of the anticipated ovulation and at the end of the menstrual cycle (10.2 +/- 7.1, 10.7 +/- 7.0 and 11.8 +/- 6.9 microg/l respectively). There was an association between leptin and LH concentrations (r= 0.37, P< 0.01) when values recorded during different time points during the cycle were plotted with each other. There was no change in serum leptin in samples taken at different times of the cyclic treatment with an oral contraceptive. There was no significant difference in mean serum leptin concentrations between women using oral contraceptives and women with no hormonal therapy. CONCLUSIONS: There is a link between serum leptin and LH concentrations during the menstrual cycle. Variations in circulating estrogen and/or progesterone concentrations have no major influence on circulating leptin in young female subjects.

The Similarities and Differences of Migraine with Aura and Migraine Without Aura: A Preliminary Study

Cephalalgia ◽  
1991 ◽  
Vol 11 (4) ◽  
pp. 189-192 ◽  
Author(s):  
R Ranson ◽  
H Igarashi ◽  
EA MacGregor ◽  
M Wilkinson
Keyword(s):  
Migraine Attack ◽  
Migraine With Aura ◽  
Migraine Without Aura ◽  
Clinical Evidence ◽  
History Of ◽  
Preliminary Study ◽  
Similarities And Differences ◽  
City Of London ◽  
The City

A preliminary study was undertaken to provide clinical evidence to support the hypothesis that: “Migraine with aura, migraine without aura and aura alone are the same condition, which differ in degree rather than pathophysiology.” At the City of London Migraine Clinic, 50 patients consecutively attending the clinic with a past or present history of migraine with aura were questioned. Of the 50 patients questioned 36 (70%) had a combination of migraine with aura, migraine without aura and/or aura alone; i.e. 70% had had more than one type of migraine attack. The duration, severity and frequency of attacks did not differ between migraine with and migraine without aura. Conclusion-the results support the hypothesis that migraine with and migraine without aura, and aura alone are not separate conditions, because: (1) most patients suffer from more than one type of migraine attack; (2) there are no significant differences in the characteristics of the migraine attacks in the different groups; (3) there are no significant differences in the characteristics of the subjects.

scholarly journals Gangguan Pola Siklus Haid pada Pesenam di Kota Pekanbaru

2020 ◽  
Vol 10 (2) ◽  
pp. 147-157
Author(s):  
Muhammad Muzakir Fahmi ◽  
Syamsul Bahri Riva’i ◽  
Nurlisis
Keyword(s):  
Menstrual Cycle ◽  
P Value ◽  
Menstrual Disorders ◽  
Chi Square ◽  
Cross Sectional ◽  
Menstrual Cycles ◽  
Factors Associated ◽  
Survey Results ◽  
Cycle Disorders ◽  
The City

The average menstrual cycle obtained in the average menstrual cycle survey results was 29.51 days. Some experienced menstrual cycles of more than 35 days (oligomenore) of 10.29% and menstrual cycles of less than 21 days (polimenore) of 1.5%. There are 26.47% with a duration of menstruation more than 8 days. Furthermore, in the turn of the pads with a mean of 2.99 times per day, replace the pads. But there are some excessive dressing changes (> 3 times), while guessing that you experience excessive menstruation with a percentage of 23.5%. There were 63% of women having menstrual disorders with the highest type of disorder 91.7% of other disorders related to menstruation, followed by menstrual disorders 25%, and menstrual cycle disorders 5%. With the average duration of menstruation obtained at 7.16 days which still includes the normal range of 2 to 8 days. Then research was conducted to find out the dominant factors associated with menstrual cycle pattern disorders. With the aim of analyzing the factors associated with menstrual cycle pattern disturbances in gymnasts in the city of Pekanbaru in 2018. This type of cross-sectional analytic study used a sample of 210 gymnasts in the city of Pekanbaru with inclusion and exclusion criteria. Statistical test uses Bivariate (chi square) and Simple Linear Multivaritic Regression. Variables that are significantly associated with p-value 0.20 is 2.7 times the disease history variable at risk of menstrual cycle pattern disorders.

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