scholarly journals Antifungal activity of microbiological drugs in relation to pathogens from the genus Fusarium Link

2021 ◽  
Vol 34 ◽  
pp. 04012
Author(s):  
Irina Astapchuk ◽  
Andrei Nasonov

As a result of studying the antifungal activity of biological drugs against fungi of the genus Fusarium, causative agents of rot of roots and fruits of the apple tree, both weak and very strong mycoparasitism were noted, but in most variants of the experiment, competition for area of nutrition prevailed. Under the influence of some drugs, the shape, edge and color of the fungus colony changed. In general, for the entire sample of pathogens, the best bioagents were antagonists of the drug Trichocin, WP, which suppressed all 5 strains with Biological efficiency (BE) 50-90 % and showed hyperparasitism in 1 strain; and the drug Alirin B, WP, which inhibited the growth of 3 strains with BE 56-85 %, showing antibiosis or fungistatic antibiotic antagonism with the formation of a “sterile” zone.

2009 ◽  
Vol 49 (2) ◽  
pp. 141-144 ◽  
Author(s):  
Kitherian Sahayaraj ◽  
Jesu Francis Borgio ◽  
Ganapathy Raju

Antifungal Activity of Three Fern Extracts on Causative Agents of Groundnut Early Leaf Spot and Rust DiseasesAntimycotic activity of three fern extracts fromHemionitis arifolia(Burm.f.) Moore.,Pteridium aquilinum(Linn.) Kuhn. andChristella parasitica(Linn.) H. Lev. were evaluated against groundnut early leaf spot and rust disease causative agentsviz., Puccinia arachidisSpeg. andPhaeoisariopsis personata(Berk & M.A. Cuortis) Vanarx., espectively by mycelial dry weight method. Both the fungi were sensitive to all the three fern extracts tested. Among the extracts, chloroform extract ofH. arifoliawas found to have maximum antifungal activity against both fungi. Between these two fungi,P. personatawas found to be more sensitive to the tested plant extracts thanP. arachidis.From this study it is concluded that chloroform extract fromH. arifoliacan be utilized for managing rust and leaf spots diseases on groundnut.


2021 ◽  
Vol 5 (71) ◽  
pp. 219-233
Author(s):  
Irina Leonidovna Astapchuk ◽  
◽  
Galina Valentinovna Yakuba ◽  
Andrei Ivanovich Nasonov ◽  
◽  
...  

2020 ◽  
Vol 25 ◽  
pp. 06002
Author(s):  
Irina Astapchuk ◽  
Galina Yakuba ◽  
Andrei Nasonov

Root rot poses a serious threat to the main fruit crop domestic apple in nurseries and young orchards. Obtaining healthy planting material, free from root pathogens and root rot, is an especially priority task in conditions of intensive production. In the process of analyzing the affected plants from nurseries and young orchards at four sampling points, pathogens of apple root rot from 11 genera were identified and 431 isolates were extracted. The most common causative agents of apple root rot seedlings in the entire studied sample were species of the genus Fusarium spp. Soil micromycetes such as Rhizoctonia spp., Cladosporium spp., Cylinrocarpon spp., and oomycetes from the genus Pythium were rare. The composition and occurrence of species were heterogeneous at different points in the studied region. Phomopsis mali (Schulzer & Sacc.) Died., Cytospora spp., Alternaria alternate (Fr.) Keissl., and Aspergillus niger Tiegh. have been associated with root rot of seedlings and young apple trees.


2010 ◽  
Vol 171 (4) ◽  
pp. 267-271 ◽  
Author(s):  
Cheila Denise Ottonelli Stopiglia ◽  
Fabiane Jamono Vieira ◽  
Andressa Grazziotin Mondadori ◽  
Tércio Paschke Oppe ◽  
Maria Lúcia Scroferneker

Molecules ◽  
2019 ◽  
Vol 24 (20) ◽  
pp. 3686 ◽  
Author(s):  
Wang ◽  
Tian ◽  
Tian ◽  
Yan ◽  
Huang ◽  
...  

Abstract: Apple tree canker infected by Valsa mali var. mali is a serious and widely distributed disease in China. Saccharothrix yanglingensis Hhs.015 is an endophytic actinomycete isolated from cucumber roots, and it has been proven that this strain is a promising biocontrol agent on apple tree canker in previous studies. The aim of this study was to elucidate the active ingredients in its metabolites. Two pentaene macrolides, WH01 and WH02, were isolated from strain Hhs.015, and their structures were elucidated based on the extensive spectroscopic analysis. WH01 and WH02 were identified as fungichromin and 1′-deoxyfungichromin, among which WH02 is a novel compound. These two compounds showed strong in vitro and in vivo antifungal activity against V. mali. By comparison of the structures of hyphae cells treated by pure compound and fermentation broth, it has been proven that pentaene macrolides are the main active ingredients in the metabolites of strain Hhs.015. This is the first report on the antifungal activity of fungichromin and its analogs on V. mali, and the 28-member pentaene macrolides were also firstly isolated from the genus of Saccharothrix.


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Francislene J. Martins ◽  
César A. Caneschi ◽  
Mônica P. Senra ◽  
Gustavo S. G. Carvalho ◽  
Adilson D. da Silva ◽  
...  

Nitrogenated heterocyclic compounds are present in both natural and synthetic drugs, and hexahydropyrimidine derivatives may prove to be efficient in treating dermatomycosis causing fungi. This study evaluated the antifungal activity of four hexahydropyrimidine derivatives against the dermatomycosis causing fungi. These derivatives were synthesized, characterized, and assessed in terms of their activity against Trichophyton mentagrophytes, Microsporum canis, Microsporum gypseum, Trichophyton rubrum, Fusarium oxysporum, and Epidermophyton floccosum between concentrations 7.8 and 1,000 μg mL−1. Scanning electron micrographs were assessed for the active derivatives and reference drugs, and these micrographs revealed that new agents cause morphological changes in fungi. The derivatives HHP1, HHP3, and HHP4 revealed poor activity against the four fungal strains (MICs range 500–1000 μg mL−1). Compound HHP3 was found to be the best potential antifungal agent among those tested and was the most effective among all the active derivatives that caused morphological changes in the susceptible strains.


2020 ◽  
Vol 21 ◽  
pp. 00005
Author(s):  
Irina Astapchuk ◽  
Galina Yakuba ◽  
Andrei Nasonov

For horticulture in the North Caucasus, and Southern Russia as a whole, root rot of fruit crops is a serious problem, especially in nurseries and young gardens. In recent years, the harmfulness of species of the genus Fusarium Link as pathogens of root rot in the apple tree of domestic Malus domestica Borkh has been increasing. As a result of the studies, 115 samples of seedlings from four examined regions of Southern Russia were studied, 264 fungal isolates were isolated, among which 11 species of the genus Fusarium were found. The composition and occurrence of species were heterogeneous at its various sampling points. So, in the industrial gardens of the Krasnodar Territory and Karachay-Cherkess Republic, species F. sporotrichioides Sherb. and F. oxysporum Schltdl. prevailed, in the Belgorod region – F. sambucinum Fuskel, in the Rostov region -F. sporotrichioides and F. proliferatum Matsush. The most common pathogens of rotting roots of apple seedlings in the entire studied sample were: F. sporotrichioides – 81 isolates, F. proliferatum – 37 isolates and F. oxysporum – 35 isolates. The rare species among the sample were F. avenaceum – isolates, as well as the pathogens that we isolated for the first time in the region as rot pathogens of F. solani (Mart.) Sacc. and F. poae (Peck) Wollenw.


Holzforschung ◽  
2013 ◽  
Vol 67 (4) ◽  
pp. 473-478 ◽  
Author(s):  
Young Min Lee ◽  
Joo-Hyun Hong ◽  
Hanbyul Lee ◽  
Byoung Jun Ahn ◽  
Gyu-Hyeok Kim ◽  
...  

Abstract Microorganism-based biological protections are alternatives to chemical treatments. Worldwide, Fusarium species are important plant pathogens, and their mycotoxins are antimicrobial. In this study, 18 Fusarium strains isolated in Korea have been investigated. Nine Fusarium species, including two unknown species, were identified based on their genotypic characteristics. Among the identified species, Fusarium armeniacum and Fusarium commune were observed for the first time in Korea. The antifungal activity of Fusarium crude extracts was assessed by growth inhibition against two wood-decay fungi and three sapstain fungi. Most Fusarium strain extracts revealed strong antifungal activity against wood-decay fungi. Strains of the unknown Fusarium sp. 2, which was found in wood samples, showed strong antifungal activity against all wood-decay and sapstain fungi tested in this study.


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