scholarly journals Composites Similarity Analysis Method Based on Knowledge Set in Composites Quality Control

2016 ◽  
Vol 61 ◽  
pp. 05011
Author(s):  
Haifeng Li
Keyword(s):  
Quality Control ◽  
Similarity Analysis ◽  
Analysis Method ◽  
Knowledge Set

Development of Simultaneous Analysis Method for Multi-Compounds Content of New Shilajit Using HPLC-UV and the Cognitive Enhancing Effect: Mongolian Shilajit

2021 ◽  
Vol 16 (7) ◽  
pp. 1934578X2110304
Author(s):  
SukJin Lee ◽  
HyeSung Ryu ◽  
WanKyunn Whang
Keyword(s):  
Quality Control ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
High Resolution Mass Spectrometry ◽  
Radical Scavenging ◽  
Original Material ◽  
Analysis Method ◽  
Quality Control Standard ◽  
Quantitative Hplc Analysis

Shilajit has a longstanding use as an anti-aging and memory enhancing drug. It is known to have excellent anti-bacterial effects and is believed to be effective for cognitive enhancement, but is difficult to standardize because of the lack of quality control standards. This study, for the first time, proposes a quality control standard using a simultaneous analytical method for the drug’s multi-compound content using high-performance liquid chromatography-ultraviolet detection (HPLC-UV) as an aid for the internationalization of Mongolian Shilajit. Phenolic compounds 1-6 were isolated from Mongolian Shilajit extract using bioassay-guided isolation, and the isolated compounds were evaluated for cognitive-related anti-Alzheimer’s disease (AD) activities using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), β-site amyloid precursor protein-cleaving enzyme 1 (BACE1), and advanced glycation end-product (AGE) formation assays. The isolated compounds showed good effects for each activity. In addition, the isolated compounds were successfully quantified using a validated quantitative HPLC analysis method. As a result, the isolated compounds were suggested as standard marker compounds for Mongolian Shilajit. Also, we proved that the original material of Mongolian Shilajit is a lichen named Xanthoparmelia somloensis (Gyel.) Hale using HPLC-UV, ultra-high-performance liquid chromatography-electrospray ionization/hybrid linear trap-quadruple-orbitrap-high-resolution mass spectrometry (UHPLC-ESI/LTQ-HRMS).

An Improved Multivariate Image Analysis Method for Quality Control of Nanofiber Membranes

2011 ◽  
Vol 44 (1) ◽  
pp. 12066-12071
Author(s):  
Pierantonio Facco ◽  
Andrea Masiero ◽  
Fabrizio Bezzo ◽  
Alessandro Beghi ◽  
Massimiliano Barolo
Keyword(s):  
Quality Control ◽  
Image Analysis ◽  
Analysis Method ◽  
Image Analysis Method ◽  
Multivariate Image Analysis ◽  
Nanofiber Membranes ◽  
Multivariate Image

scholarly journals ANALISIS PENGENDALIAN KUALITAS PRODUK DI CV. BILO DATANG

2020 ◽  
Vol 12 (2) ◽  
pp. 179-190
Author(s):  
Aloysius Pansewidi ◽  
Ronald P C Fanggidae ◽  
Reyner F Makatita
Keyword(s):  
Quality Control ◽  
Production Process ◽  
Descriptive Analysis ◽  
Control Level ◽  
Analysis Method ◽  
Product Quality Control ◽  
Quantitative Descriptive Analysis ◽  
Quality Control Level ◽  
Quantitative Descriptive ◽  
Diagram Analysis

The purpose of this study is to analyze the level and the type of damage in the production process CV.Bilo Datang and the solutions of quality control are carried out. The method used in this research is quantitative descriptive analysis method using Pareto diagram analysis tools and Cause-effect diagrams. The results of the study showed that the quality control conducted by the company was less than optimal, especially in controlling for half defective products. This is due to several things such as lack of employee skills and maintenance of machinery and equipment that is less than the maximum resulting in the product being half defective. Although in the amount of damage is greater than half defective products but there are also products damaged due to pest attack on wood. The solution provided by the researcher is also appropriate to the stage of the damage that occurred. Keywords: Product Quality Control, Level of damage and Type of damage

Evaluation of stability using one versus three tubes for each quality control concentration in matrix-based bioanalysis

Bioanalysis ◽  
2019 ◽  
Vol 11 (20) ◽  
pp. 1823-1834 ◽  
Author(s):  
Sam H Haidar ◽  
Diaa Shakleya ◽  
Jiang Wang ◽  
Xiaohan Cai ◽  
Patrick Faustino
Keyword(s):  
Quality Control ◽  
Salicylic Acid ◽  
Stability Testing ◽  
Analysis Method ◽  
Single Tube ◽  
Pharmaceutical Firms ◽  
Concentration Method ◽  
Research Organizations ◽  
Significant Difference ◽  
Tenofovir Alafenamide

Aim: Contract research organizations and pharmaceutical firms have performed stability testing using one of two methods: storing in the freezer a single tube of matrix for each quality control concentration (Method 1), followed by aliquoting and analysis; and storing three tubes for each quality control concentration, followed by analysis (Method 2). This research project was conducted to determine if there were detectable differences between Method 1 and Method 2. Methodology: Five model drugs were selected: teriflunomide (stable compound) and acetyl salicylic acid, simvastatin, tenofovir alafenamide and valganciclovir (stability concerns). Samples were stored at -80°C for 1, 3 and 12 months and then analyzed. Samples were also placed at different locations within the freezer. Results: For the drugs tested, the results suggest that there is no significant difference in the outcome of stability testing, regardless whether Method 1 or Method 2 was followed.

scholarly journals Fingerprint Analysis of Ginkgo biloba Leaves and Related Health Foods by High-Performance Liquid Chromatography/Electrospray Ionization-Mass Spectrometry

2010 ◽  
Vol 93 (6) ◽  
pp. 1798-1805 ◽  
Author(s):  
Jiajia Song ◽  
Guozhen Fang ◽  
Yan Zhang ◽  
Qiliang Deng ◽  
Shuo Wang
Keyword(s):  
Electrospray Ionization ◽  
Ginkgo Biloba ◽  
High Performance ◽  
Quality Evaluation ◽  
Similarity Analysis ◽  
Ionization Mass ◽  
Analysis Method ◽  
Fingerprint Analysis ◽  
Wide Range ◽  
Different Sources

Abstract A fingerprint analysis method was developed for Ginkgo biloba leaves and was successfully used for quality evaluation of related health foods by HPLC with electrospray ionization MS. Fifteen samples of G. biloba leaves, which were collected from 15 different locations in China, were analyzed and identified in this study. By both peak analysis and similarity analysis of the fingerprint chromatograms, variation of constituents was easily observed in the leaves from different sources. By comparison with batches of authentic leaves, the authenticity, and quality consistency of related health foods in different matrixes were effectively estimated. It is important to mention that studying a wide range of authentic leaves from various habitats made the quality evaluation of commercial products more convincing and reasonable. The fingerprint-based strategy of the developed method should provide improved QC of G. biloba leaves and products.

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