Recovery from Strenuous Downhill Running in Young and Older Physically Active Adults

2019 ◽  
Vol 40 (11) ◽  
pp. 696-703 ◽  
Author(s):  
Koichiro Hayashi ◽  
Miriam E. Leary ◽  
Stephen J. Roy ◽  
Jitanan Laosiripisan ◽  
Evan P. Pasha ◽  
...  
Keyword(s):  
Older Adults ◽  
Maximal Oxygen Consumption ◽  
Pain Scale ◽  
Creatine Kinase Activity ◽  
Strenuous Exercise ◽  
Trained Group ◽  
Physically Active ◽  
Downhill Running ◽  
Rate Of Recovery ◽  
Muscle Groups

AbstractThere is a well-conceived notion that rate of recovery from strenuous exercise gets slower with age. However, it is unclear whether older adults who exercise habitually demonstrate slower rates of recovery. We determined whether older adults who are physically active demonstrate slower rates of recovery from unaccustomed strenuous exercise compared with younger peers. Healthy young sedentary (n=10, 28±2 years), young endurance-trained (n=15, 27±2 years), and older endurance-trained (n=14, 58±2 years) men and women were studied. Participants performed 45 min of downhill running at 65% of their maximal oxygen consumption. Visual analog pain scores of muscle groups increased at 24, 48, and 72 h in all three groups (p<0.05), and changes in the muscular pain scale of the legs was smaller in the older trained group than in the young trained group. Maximum isometric strengths at 90° decreased in all groups at 24 h, but the recovery rates were not different at 72 h among the groups. Plasma creatine kinase activity and myoglobin concentration increased at 24 h following downhill running and returned to baseline at 48 h in both the young and older trained groups. The present findings are not consistent with the prevailing notion that older trained adults have a slower rate of recovery from strenuous exercise.

scholarly journals Sport Involvement Among Middle-Aged and Older Adults With Arthritis: Motivations and Constraints to Participation

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 405-405
Author(s):  
Megan Janke ◽  
Julie Son ◽  
Jill Naar ◽  
Stephanie West ◽  
Toni Liechty ◽  
...  
Keyword(s):  
Older Adults ◽  
Sport Participation ◽  
The United States ◽  
Functional Mobility ◽  
Online Questionnaire ◽  
Physically Active ◽  
Social Wellbeing ◽  
Constraint Negotiation ◽  
Active Leisure ◽  
Physically Active Leisure

Abstract Although participation in physical activity is recommended for adults with arthritis, research indicates individuals often stop participating in sports and physically active leisure due to the pain and symptoms associated with arthritis (Wilcox et al., 2006). Examining a group of older adults with arthritis, the present study examines motivations and constraints related to participating in sport and physically active leisure as well as how they negotiate constraints. Data (N=1203) were collected through an online questionnaire of adults aged 50 and older in the United States. This study includes individuals reporting a diagnosis of some form of arthritis (n=288; M age = 64.8, SD = 8.08). Approximately 32% self-reported participation in sport in the past 12 months. Descriptive statistics were conducted to explore motivations and constraints to sport involvement. Regressions were run to determine whether constraints and motivations explained adults’ functional mobility and social wellbeing. The most commonly identified motivation for participation was for health purposes (80.2%). Constraints to participation included not being in good enough shape (51.9%) and not having others their age with whom to participate (47.4%). The most commonly identified constraint negotiation was to budget money (51.4%); this is not surprising since sport participation was perceived as expensive (41.3%). Motivations (p&lt;.01) and constraints (p&lt;.001) significantly predicted functional mobility; constraints significantly predicted some aspects of social wellbeing (i.e., coherence, contribution, actualization; p&lt;.05) while constraint negotiation predicted social acceptance (p&lt;.05) and integration (p&lt;.001). Discussion will include implications and strategies for agencies and professionals who work with adults who have arthritis.

scholarly journals Profiles of Loneliness and Social Isolation in Physically Active and Inactive Older Adults in Rural England

2021 ◽  
Vol 18 (8) ◽  
pp. 3971
Author(s):  
Jolanthe de Koning ◽  
Suzanne H. Richards ◽  
Grace E. R. Wood ◽  
Afroditi Stathi
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Social Isolation ◽  
Physical Environment ◽  
Vigorous Physical Activity ◽  
Social Contact ◽  
Physical Activity Behaviour ◽  
Rural Setting ◽  
Structured Interviews ◽  
Physically Active

Objective: Loneliness and social isolation are associated with higher risk of morbidity and mortality and physical inactivity in older age. This study explored the socioecological context in which both physically active and inactive older adults experience loneliness and/or social isolation in a UK rural setting. Design: A mixed-methods design employed semi structured interviews and accelerometer-measured moderate-to-vigorous physical activity (MVPA). Interviews explored the personal, social and environmental factors influencing engagement with physical activities, guided by an adapted-socioecological model of physical activity behaviour. Findings: Twenty-four older adults (MeanAge = 73 (5.8 SD); 12 women) were interviewed. Transcripts were thematically analysed and seven profiles of physical activity, social isolation and loneliness were identified. The high-MVPA group had established PA habits, reported several sources of social contact and evaluated their physical environment as activity friendly. The low MVPA group had diverse experiences of past engagement in social activities. Similar to the high MVPA, they reported a range of sources of social contact but they did not perceive the physical environment as activity friendly. Conclusions: Loneliness and/or social isolation was reported by both physically active and inactive older adults. There is wide diversity and complexity in types and intensity of PA, loneliness and social isolation profiles and personal, social and environmental contexts.

scholarly journals iNOS-dependent sweating and eNOS-dependent cutaneous vasodilation are evident in younger adults, but are diminished in older adults exercising in the heat

2016 ◽  
Vol 120 (3) ◽  
pp. 318-327 ◽  
Author(s):  
Naoto Fujii ◽  
Robert D. Meade ◽  
Lacy M. Alexander ◽  
Pegah Akbari ◽  
Imane Foudil-bey ◽  
...  
Keyword(s):  
Older Adults ◽  
Intermittent Exercise ◽  
Sweat Rate ◽  
Fixed Rate ◽  
Younger Adults ◽  
Physically Active ◽  
Cutaneous Vasodilation ◽  
Inos Inhibitor ◽  
Oxide Synthase ◽  
Inos Inhibition

Nitric oxide synthase (NOS) contributes to sweating and cutaneous vasodilation during exercise in younger adults. We hypothesized that endothelial NOS (eNOS) and neuronal NOS (nNOS) mediate NOS-dependent sweating, whereas eNOS induces NOS-dependent cutaneous vasodilation in younger adults exercising in the heat. Further, aging may upregulate inducible NOS (iNOS), which may attenuate sweating and cutaneous vasodilator responses. We hypothesized that iNOS inhibition would augment sweating and cutaneous vasodilation in exercising older adults. Physically active younger ( n = 12, 23 ± 4 yr) and older ( n = 12, 60 ± 6 yr) adults performed two 30-min bouts of cycling at a fixed rate of metabolic heat production (400 W) in the heat (35°C). Sweat rate and cutaneous vascular conductance (CVC) were evaluated at four intradermal microdialysis sites with: 1) lactated Ringer (control), 2) nNOS inhibitor (nNOS-I, NPLA), 3) iNOS inhibitor (iNOS-I, 1400W), or 4) eNOS inhibitor (eNOS-I, LNAA). In younger adults during both exercise bouts, all inhibitors decreased sweating relative to control, albeit a lower sweat rate was observed at iNOS-I compared with eNOS-I and nNOS-I sites (all P < 0.05). CVC at the eNOS-I site was lower than control in younger adults throughout the intermittent exercise protocol (all P < 0.05). In older adults, there were no differences between control and iNOS-I sites for sweating and CVC during both exercise bouts (all P > 0.05). We show that iNOS and eNOS are the main contributors to NOS-dependent sweating and cutaneous vasodilation, respectively, in physically active younger adults exercising in the heat, and that iNOS inhibition does not alter sweating or cutaneous vasodilation in exercising physically active older adults.

scholarly journals Increased proinflammatory and oxidant gene expression in circulating mononuclear cells in older adults: amelioration by habitual exercise

2011 ◽  
Vol 43 (14) ◽  
pp. 895-902 ◽  
Author(s):  
Lindsey B. Gano ◽  
Anthony J. Donato ◽  
Gary L. Pierce ◽  
Hamza M. Pasha ◽  
Katherine A. Magerko ◽  
...  
Keyword(s):  
Gene Expression ◽  
Older Adults ◽  
Aerobic Exercise ◽  
Exercise Intervention ◽  
Mononuclear Cells ◽  
Maximal Oxygen Consumption ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
Maximal Heart Rate ◽  
Peripheral Blood Mononuclear ◽  
Monocyte Chemoattractant Protein 1

We tested the hypothesis that peripheral blood mononuclear cells (PBMC) of older adults demonstrate a proinflammatory/-oxidative gene expression profile that can be improved by regular aerobic exercise. PBMC were isolated from young ( n = 25, 18–33 yr) and middle-aged/older ( n = 40, 50–76 yr) healthy adults. The older adults had greater mRNA expression (real-time RT-PCR) of the proinflammatory/-oxidant transcription factor nuclear factor-κB (1.58-fold, P < 0.05) and receptor for advanced glycation end products (1.12-fold, P < 0.05), the proinflammatory cytokines tumor necrosis factor-α (1.90-fold, P < 0.05) and monocyte chemoattractant protein-1 (1.47-fold, P < 0.05), and the oxidant-producing enzymes nicotinamide adenine dinucleotide phosphate-oxidase (0.91-fold, P < 0.05) and inducible nitric oxide synthase (2.60-fold, P < 0.05). In 11 subjects (58–70 yr), maximal oxygen consumption (+11%) and exercise time (+19%) were increased (both P < 0.001), and expression of the above proinflammatory/-oxidative genes was or tended to be decreased in PBMC after vs. before 2 mo of aerobic exercise (brisk walking ∼6 days/wk, 50 min/day, 70% of maximal heart rate). Expression of interleukin-6 was not different with age or exercise intervention. Age group- and exercise intervention-related differences in gene expression were independent of other factors. PBMC of healthy older adults demonstrate increased expression of several genes associated with inflammation and oxidative stress, which is largely ameliorated by habitual aerobic exercise. This proinflammatory/-oxidative gene signature may represent a therapeutic target for lifestyle and pharmacological prevention and treatment strategies.

Relationship Between Mental Health, Resilience, and Physical Activity in Older Adults: A 2-Year Longitudinal Study

2021 ◽  
pp. 1-9
Author(s):  
Maria Priscila Wermelinger Ávila ◽  
Jimilly Caputo Corrêa ◽  
Alessandra Lamas Granero Lucchetti ◽  
Giancarlo Lucchetti
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Older Adults ◽  
Regression Models ◽  
Linear Regression Models ◽  
Physically Active ◽  
Effective Interventions ◽  
Self Sufficiency ◽  
The Relationship

The aim of this study was to longitudinally investigate the association between resilience and mental health in older adults and to determine the influence of physical activity on this relationship. A total of 291 older adults were included in a 2-year follow-up study. Adjusted linear regression models evaluated the association between resilience at baseline and mental health after 2 years in sufficiently and insufficiently physically active older adults. A negative correlation was found between resilience at baseline and depression, anxiety, and stress after 2 years for the overall sample. This association changed after stratifying the group. Sufficiently physically active individuals made greater use of the resilience components “Self-Sufficiency” and “Perseverance,” whereas insufficiently physically active individuals made greater use of “Meaning of Life” and “Existential Singularity.” Physical activity can influence the relationship between resilience and mental health. These results can help guide the devising of more effective interventions for this age group.

Strenuous exercise decreases the percentage of type 1 T cells in the circulation

2001 ◽  
Vol 91 (4) ◽  
pp. 1708-1712 ◽  
Author(s):  
Adam Steensberg ◽  
Anders Dyhr Toft ◽  
Helle Bruunsgaard ◽  
Marie Sandmand ◽  
Jens Halkjær-Kristensen ◽  
...  
Keyword(s):  
T Cells ◽  
Peak Plasma ◽  
Maximal Oxygen Consumption ◽  
Interferon Γ ◽  
Treadmill Running ◽  
Strenuous Exercise ◽  
Plasma Epinephrine ◽  
Lymphocyte Number

Prolonged strenuous exercise is followed by a temporary functional immune impairment. Low numbers of CD4+T helper (Th) and CD8+ T cytotoxic (Tc) cells are found in the circulation. These cells can be divided according to their cytokine profile into type 1 (Th1 and Tc1), which produce interferon-γ and interleukin (IL)-2, and type 2 (Th2 and Tc2) cells, which produce IL-4. The question addressed in the present study was whether exercise affected the relative balance between the circulating levels of these cytokine-producing T cells. Nine male runners performed treadmill running for 2.5 h at 75% of maximal oxygen consumption. The intracellular expression of cytokines was detected following stimulation with ionomycin and phorbol 12-myristate 13-acetate in blood obtained before, during, and after exercise. The percentage of type 1 T cells in the circulation was suppressed at the end of exercise and 2 h after exercise, whereas no changes were found in the percentage of type 2 T cells. Plasma epinephrine correlated negatively with the percentage of circulating CD8+ T cells producing IL-2, whereas peak IL-6 correlated with the percentage of CD8+ IL-4-producing T cells in the circulation. Peak plasma IL-6 correlated with plasma cortisol postrunning. In conclusion, the postexercise decrease in T lymphocyte number is accompanied by a more pronounced decrease in type 1 T cells, which may be linked to high plasma epinephrine. Furthermore, IL-6 may stimulate type 2 T cells, thereby maintaining a relatively unaltered percentage of these cells in the circulation compared with total circulating lymphocyte number.

Meta-analysis of the age-associated decline in maximal aerobic capacity in men: relation to training status

2000 ◽  
Vol 278 (3) ◽  
pp. H829-H834 ◽  
Author(s):  
Teresa M. Wilson ◽  
Hirofumi Tanaka
Keyword(s):  
Meta Analysis ◽  
Maximal Oxygen Consumption ◽  
Group Differences ◽  
Maximal Heart Rate ◽  
Maximal Aerobic Capacity ◽  
Cross Sectional ◽  
Physically Active ◽  
Age Related ◽  
Rate Of Decline ◽  
Exercise Status

Based on cross-sectional data, we recently reported that, in contrast to the prevailing view, the rate of decline in maximal oxygen consumption (V˙o 2 max) with age is greater in physically active compared with sedentary healthy women. We tested this hypothesis in men using a meta-analytic study ofV˙o 2 max values in the published literature. A total of 242 studies (538 subject groups and 13,828 subjects) met the inclusion criteria and were arbitrarily separated into sedentary (214 groups, 6,231 subjects), active (159 groups, 5,621 subjects), and endurance-trained (165 groups, 1,976 subjects) populations. Body fat percent increased with age in sedentary and active men ( P < 0.001), whereas no change was observed in endurance-trained men.V˙o 2 max was inversely and strongly related to age within each population ( r = −0.80 to −0.88, all P < 0.001) and was highest in endurance-trained and lowest in sedentary populations at any age. Absolute rates of decline inV˙o 2 max with age were not different ( P > 0.05) in sedentary (−4.0 ml ⋅ kg−1 ⋅ min−1 ⋅ decade−1), active (−4.0), and endurance-trained (−4.6) populations. Similarly, there were no group differences ( P > 0.05) in the relative (%) rates of decline inV˙o 2 max with advancing age (−8.7, −7.3, and −6.8%/decade, respectively). Maximal heart rate was inversely related to age within each population ( r = −0.88 to −0.93, all P < 0.001), but the rate of age-related reduction was not different among the populations. There was a significant decline in running mileage and speed with advancing age in the endurance-trained men. The present cross-sectional meta-analytic findings do not support the hypothesis that the rate of decline inV˙o 2 max with age is related to habitual aerobic exercise status in men.

Exercise-induced cardiac hypertrophy: a correlation of blood flow and microvasculature

1986 ◽  
Vol 60 (4) ◽  
pp. 1259-1267 ◽  
Author(s):  
E. A. Breisch ◽  
F. C. White ◽  
L. E. Nimmo ◽  
M. D. McKirnan ◽  
C. M. Bloor
Keyword(s):  
Blood Flow ◽  
Aortic Pressure ◽  
Left Ventricular ◽  
Treadmill Running ◽  
Adenosine Infusion ◽  
Strenuous Exercise ◽  
Luminal Surface ◽  
Trained Group ◽  
Cross Sectional ◽  
Maximum Exercise

The effects of exercise conditioning on the myocardium were studied in seven instrumented pigs strenuously exercised for 12 wk by treadmill running. Data were compared with eight instrumented untrained pigs. O2 consumption measured during maximum exercise effort was significantly elevated in the trained pigs (71.7 +/- 4.0 vs. 56.3 +/- 3.0 ml X ml-1 X kg-1). Absolute right and left ventricular mass increased by 20 and 13%, respectively, in response to exercise. Myocyte cross-sectional area increased by 21% in the trained hearts compared with the untrained hearts. Transmural left ventricular myocardial blood flow (ml X min-1 X g-1) was not significantly different at rest, during maximum exercise, or during exercise with adenosine infusion. However, training caused an elevation of the regional epicardial blood flow noted during exercise and exercise with adenosine. In the trained pigs mean aortic pressure during maximum exercise with adenosine infusion was not significantly different compared with untrained pigs. Coronary resistance during exercise with adenosine infusion was the same in both animal groups. In the trained group capillary numerical (no./mm2) and length (mm/mm3) densities were reduced, whereas arteriolar numerical and length densities were significantly increased compared with the untrained group. Measurements of capillary luminal surface density (mm2/mm3) in the trained group were unchanged compared with the untrained group. These results suggest that strenuous exercise does not stimulate the production of new capillaries, but this is modified by the ability of existing capillaries to increase their luminal surface area to parallel increases in myocyte growth. The arteriolar data suggest that exercise promotes the formation of new arterioles.(ABSTRACT TRUNCATED AT 250 WORDS)

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