scholarly journals Dentin Tubular Occlusion with Bioactive Glass Containing Dentrifice and Gluma Desensitizer–A Comparative Sem Evaluation

2014 ◽  
Vol 02 (01) ◽  
pp. 016-021
Author(s):  
Ashu Gupta ◽  
Neha Sharma ◽  
Manmohan Bramta

AbstractDentinal hypersensitivity (DH) is a painful clinical condition and is characterized by pain arising from exposed dentin in response to various stimuli. Various treatment modalities are available to treat dentinal hypersensitivity which include at-home and in-office treatment. At home treatment generally consists of a variety of dentrifices containing different constituents like stannous fluoride, strontium chloride and potassium oxalate. These agents cause occlusion of dentinal tubules which decreases both dentine permeability and fluid movement thereby reducing hypersensitivity. Recently, bioactive glass (NovaMin) has been incorporated as a remineralising ingredient in dentifrice formulations for treating Dentinal Hyprsensitivity. It relieves the symptoms by precipitating hydroxycarbonate apatite (HCA) onto the tooth surface. Another combination product consisting of an aqueous solution of 5% glutaraldehyde and 35% hydroxyethyl methacrylate (Gluma desensitizer) has also been reported to be an effective desensitizing agent. Thus, the aim of the study was to evaluate and compare the tubule occluding effect of of two desensitizing agents, which are bioactive glass (Novamin), and Gluma Desensitizer. In the present study bioactive glass was found to produce more completely occluded tubules while Gluma desensitizer caused more partial occlusion on initial application. Hence, NovaMin application could be more effective in providing relief from dentinal hypersensitivity when compared with Gluma Desensitizer.

2019 ◽  
Vol 8 (2) ◽  
pp. 96
Author(s):  
Profilia Shinta ◽  
Ketut Suardita ◽  
Moch. Mudjiono

Background : Dentinal hypersensitivity (DH) is a painful clinical condition and is characterized by pain arising from exposed dentin in response to various stimuli. Various treatment modalities are available to treat dentinal hypersensitivity which include at-home and in-office treatment. At home treatment generally consists of a variety of dentrifices containing different constituents like strontium chloride and bioactive glass (Novamin). These agents cause occlusion of dentinal tubules thereby reducing hypersensitivity.Purpose: This study  was  to evaluate the effects of different desensitizing dentifrices on dentinal tubule occlusion by scanning electron microscopy (SEM) of strontium chloride and bioactive glass (Novamin) pastes in the treatment of dentinehypersensitivity (DH) Methods: sixteen extractedspecimens from bovine incisors teeth with randomized into 2 groups (n=8). The crowns were removed from the root and the crown  were sectioned longitudinally into two parts (in a mesiodistaldirection). The cervical toothwere resulting in two samples per tooth.Dentinal tubules were exposedand thesamples provided a 4 mm x 4 mm area of exposed dentinal tubules.Group 1 (treated with strontium chloride), Group 2 (treated with  bioactive glass (novamin))After each treatment for seven days, tubule occlusion on dentin were analyzed by scanning electron microscopy  (SEM).The data were analyzed using “mann-whitneytest” (p<0.05).Result: Groups bioactive glass (novamin) showed tubule occlusion highest when compared with groups strontium chloride.Conclusion: bioactive glass (novamin) paste showed tubule occlusion highest with strontium chloride


2004 ◽  
Vol 12 (2) ◽  
pp. 144-148 ◽  
Author(s):  
César Augusto Galvão Arrais ◽  
Daniel Chi Ngai Chan ◽  
Marcelo Giannini

The aim of this study was to evaluate the features of dentinal tubules occlusion following application of three commercially available desensitizing agents: potassium oxalate-based / Oxa-Gel (OX), HEMA and glutaraldehyde-based / Gluma Desensitizer (GD) and acidulated phosphate fluoride-based / Nupro Gel (AF). Buccal cervical areas of twenty-four extracted human third molars were smoothed and wet-polished with SiC papers and diamond pastes, in order to simulate the clinical aspect of hypersensitive dentin cervical surfaces. The teeth were randomly divided into four groups (n=6), according to the dentin surface treatments: G1: untreated; G2: OX; G3: GD; G4: AF. Specimens were fractured in the lingual-buccal direction and prepared for SEM analysis. OX promoted tubule occlusion by crystal-like deposits in the lumen of the tubules. While GL created a thin layer over the dentin surface, AF application produced precipitates that occluded the tubules. According to the SEM analysis, all desensitizing agents were able to occlude the dentinal tubules.


Author(s):  
Dr. Madhavi Ajit Shetty ◽  
Dr. Sharad Kokate ◽  
Dr. Vibha Hegde

Aim: To comparatively evaluate the occlusion of dentinal tubules by four novel desensitizing agents for treatment of Dentinal Hypersensitivity. Materials and Methods: The Diode Laser and three commercially available Desensitizers the NovaminR group- (SHY-NMTM), Colgate Sensitive Pro-relief, Gluma were investigated in this study. 30 extracted mandibular molars were used (n=30). They were divided into 5 groups including the control group in which no treatment was done. Teeth were ground under water-cooled trimming wheel, to prepare flat dentin surfaces. The dentin surfaces were etched to remove any smear plugs and to mimic the open dentinal tubules of sensitive dentin using 0.5 M Ethylene Diamine Tetraacetic Acid (pH 7.4) for two minutes (applied with a micro brush) and then rinsed with an air-water syringe for 30 seconds.


2020 ◽  
Vol 24 (11) ◽  
pp. 4043-4049
Author(s):  
Chad J. Anderson ◽  
Gerard Kugel ◽  
Yuanshu Zou ◽  
Marco Ferrari ◽  
Robert Gerlach

Abstract Objectives To compare the effects of a stannous fluoride dentifrice and a sodium fluoride dentifrice on dentinal hypersensitivity when used with an oxalate-based regimen combining in-office and at-home treatment. Materials and methods In this single-center, randomized, controlled, double-blind, pilot clinical trial, 30 subjects were professionally treated at baseline with a 3% oxalate/potassium salt solution on up to two target teeth, then randomized 1:1 to either 0.454% stannous fluoride or 0.243% sodium fluoride overlabeled dentifrice. Both groups were given 6 sensitivity strips (3.14% potassium oxalate gel) and a soft, manual toothbrush. Subjects were permitted to apply strips on up to two teeth, up to three times per tooth, at home as desired throughout the study. Dentinal sensitivity (cold air blast challenge) was assessed at baseline, immediately after post-professional treatment, and at day 60 using the Schiff scale and a Visual Analog Scale (VAS). Results Immediately after professional oxalate treatment, the overall mean Schiff and VAS score decreased 25.6% and 22.4% from baseline, respectively (p ≤ 0.001 for both). At day 60, further reductions in both mean scores were seen in both groups. There were no significant differences between the groups at day 60. All treatments were well tolerated. Conclusions In subjects treated with oxalates for dentinal hypersensitivity, both stannous fluoride and sodium fluoride dentifrices are well tolerated, are feasible for routine use, and do not detract from the desensitizing effects of an in-office and at-home oxalate combination treatment regimen. Clinical relevance Either stannous fluoride or sodium fluoride dentifrices can be recommended to dentinal hypersensitivity patients who undergo professional oxalate treatment.


Author(s):  
Priyanka Potdar ◽  
Rohit Shah ◽  
Dipika Mitra ◽  
Samhita Dabak ◽  
Gaurav Shetty

INTRODUCTION Dentinal hypersensitivity is a common clinical condition and the treatment outcome is not consistently successful with any particular treatment modalities. Two chief methods of treatment of dentinal hypersensitivity are tubular occlusion and blockage of nerve activity. Clinicians have used many materials and techniques to treat dentinal hypersensitivity. Research has shown that Lasers effectively occlude the dentinal tubules leading to a decrease in dentinal tubule permeability, thus reducing hypersensitivity. AIM AND OBJECTIVE To evaluate the efficacy of Diode laser in dentinal hypersensitivity. MATERIALS AND METHODS The desensitizing effect of the laser was assessed in a split mouth study. 10 patients underwent the Diode laser therapy. In the test sites effect of laser application was evaluated at 30 sec, 15 mins and 7 days, whereas in the control group sham laser was used with the similar protocol as test side. Pre and post-operative score for sensitivity was recorded on a VAS scale, at 30 sec, 15 mins and 7 days based on response of the patient to the cold air blast. RESULTS / CONCLUSION Diode lasers can be used as an effective treatment option for desensitization. Key Words Hypersensitivity Tubular Occlusion, Tubule Permeability


2017 ◽  
Vol 7 (1) ◽  
pp. 43-47
Author(s):  
Aditya Mitra ◽  
Chandrani Adhikari

ABSTRACT Aim Aim of the study is to evaluate the depth of penetration of different types of desensitizing agents into the dentinal tubules in vivo. Materials and methods Twenty patients requiring tooth extraction for orthodontic purpose were selected. In all four premolars of the selected patients, small class V cavities were prepared on the buccal surface having depth of 0.5 mm. They were divided into four groups and treated with four different types of desensitizing agents (5% NaF solution, Gluma desensitizer, FluorProtector, and SuperSeal) for required time and then they were extracted. They were longitudinally sectioned and each section was studied by scanning electron microscope. Results The mean depth of penetration of SuperSeal and Gluma was significantly higher than that of other agents (sodium fluoride and FluorProtector) (p<0.05). No significant difference was found between SuperSeal and Gluma (p>0.05). Conclusion The depth of penetration of resinous desensitizing agent (Gluma) is maximum followed by potassium oxalate solution (SuperSeal) and fluoride varnish (FluorProtector). Clinical significance Deeper the penetration of desensitizing agents into the dentinal tubules, longer the efficacy. How to cite this article Mitra A, Adhikari C. Comparative Evaluation of the Depth of Penetration of different Types of Desensitizing Agents into the Dentinal Tubules: An in vivo Study. J Contemp Dent 2017;7(1):43-47.


2006 ◽  
Vol 17 (4) ◽  
pp. 300-305 ◽  
Author(s):  
Sérgio Lima Santiago ◽  
José Carlos Pereira ◽  
Ana Christina Bonato Figueiredo Martineli

This study evaluated the influence of time after application of oxalate solutions in reducing dentin hydraulic conductance. Fifty dentin discs were obtained from extracted human third molars and assigned to 5 groups (n=10), according to the desensitizing agent used: Group I: OxaGel; Group II: experimental agent DD-1: Group III: experimental agent DD-2. In Groups IV and V, a placebo gel and deionized water were used as control, respectively. The agents were applied for 3 min, washed out and the hydraulic conductance was measured immediately and at 5-, 15- and 30-min intervals, and after acid etching. Data were analyzed statistically by two-way ANOVA and Duncan's test at 5% significance level. Groups I, II and III did not differ significantly from each other in any of the time intervals (p>0.05). Likewise, Groups IV and V were statistically similar to each other (p>0.05). The active agents reduced significantly dentin permeability in comparison to control groups (p<0.05). Dentin permeability measured in vitro decreased significantly with time regardless of the agent applied (either active or control agents). The results of Group V, in which no dentin desensitizing agent was employed, indicates that the assessment of dentin permeability by this method must be interpreted with caution.


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