scholarly journals Comparative Evaluation of Salivary Interleukin-8 Levels in Diabetics, Hypertensives and Smokers with Chronic Periodontitis

2014 ◽  
Vol 02 (03) ◽  
pp. 145-149
Author(s):  
Sanjeev Jain ◽  
Harjit Kaur ◽  
Nisha Aggarwal ◽  
Milli Gupta ◽  
Divya Saxena ◽  
...  

Abstract Background: Cytokines are pivotal to the pathogenesis of periodontal disease and may be used as markers in diagnosis. Systemic diseases and smoking are considered risk factors that have been associated with periodontal disease progression. Cytokine production may also be influenced by smoking and systemic diseases leading to an imbalance that disturbs the host–parasite relationship. Aim: The aim of the present study was to determine and compare the levels of salivary IL-8 in diabetics, smokers and hypertensive patients with chronic periodontitis. Materials and method: A total of 80 patients with chronic periodontitis were included in the study. They were divided into four groups: 20 controls, 20 diabetics, 20 hypertensives and 20 smokers. Unstimulated saliva samples were collected at first visit and IL-8 levels were measured by enzyme linked immunosorbent assay (ELISA). Results: It was found that as compared to control group, diabetic group presented with higher levels of IL-8 whereas hypertensive and smoker groups presented with lower levels of IL-8. After statistical analysis it was found that this alteration was significant in smokers group only. Conclusion It can be concluded from the study that the levels of inflammatory biomarkers in chronic periodontitis patients are altered with systemic factors.

Parasitology ◽  
1987 ◽  
Vol 95 (3) ◽  
pp. 507-516 ◽  
Author(s):  
H. M. Murare ◽  
M. J. Doenhoff

SUMMARYA laboratory life-cycle ofSchistosoma boviswas established in order to study the host-parasite relationship in immunologically intact and T-cell deprived mice. Normal mice were found to have ‘self-cured’ theirS. bovisinfections almost completely by 10 weeks after cercarial administration, and there was no evidence of self-cure by day 79 in T-cell deprived animals, Thus, groups of deprived mice autopsied between 9 and 11 weeks after infection were invariably found to have greater worm burdens and a greater total number of eggs in the liver than comparably-infected normal mice. However, liver egg counts/worm pair were similar in the two types of host, and differences between normal and deprived mice with respect to totalS. bovisegg counts in the intestine were also not consistently in the same direction in all experiments. Faecal egg counts were always less in deprived mice than in normal mice, even in an experiment in which the deprived mice had a significantly higher intestinal tissue egg count than the normal control group. The results are discussed in relation to the better knownS. mansoni/mouse host-parasite relationship.


1980 ◽  
Vol 58 (4) ◽  
pp. 614-617 ◽  
Author(s):  
T. O. Al Karmi ◽  
G. M. Faubert

The parasite-induced weight gain in animals is an unusual phenomenon which involves a complex host–parasite relationship. Trichinella pseudospiralis exhibits such a phenomenon in mice. Eighty Swiss mice were orally infected with 600 T. pseudospiralis or Trichinella spiralis muscle larvae. The total body weight of the mice was recorded at the time of infection and at 2 and 10 months after, and compared with an uninfected control group. Trichinella pseudospiralis muscle larvae induced an abnormal weight gain. This weight increase is statistically different from the other two groups of mice after 2 and 10 months postinfection. The results indicate the existence of a different type of host–parasite relationship between the two parasites. Some speculative ideas are advanced to explain the rapid growth effect of T. pseudospiralis on its host.


2016 ◽  
Vol 20 (1) ◽  
pp. 29-32
Author(s):  
Alexandra Martu Maria ◽  
Irina-Georgeta Ursarescu ◽  
Sorina Solomon ◽  
Liliana Foia

SummaryThe purpose of the study was to assess the effects of LED-PAD and tolonium chloride on periodontal clinical parameters in chronic periodontitis. Materials and Methods: The study was conducted on patients with chronic periodontitis, divided in 2 groups (study group and control group of patients who, besides the conventional therapy measures, also received PAD therapy). The periodontal clinical parameters were registered at baseline and after 3 months. Results and Discussions: The post-therapy evaluation revealed significantly improved results of periodontal clinical parameters in the study group, when compared to the control group. Our results support the literature studies conducted on chronic periodontitis patients but without any systemic diseases. Conclusion: The PAD disinfection determined a significant improvement for the periodontal clinical parameters in patients with periodontal disease.


2007 ◽  
Vol 49 (5) ◽  
pp. 289-292 ◽  
Author(s):  
Jomara M. Gonçalves ◽  
Mônica C.T. Pereira ◽  
Luciene G. Evangelista ◽  
Antônio C.R. Leite

Expression of circulating white blood cells was investigated in rats (Rattus norvegicus) experimentally infected with larvae of Dermatobia hominis, the human bot fly. Leucocytes were counted prior to infection (control group) as well as at 6, 10, 15, 20 and 28 days post-infection (dpi) and at 7, 15, 30 and 60 days post-larval emergence (dple). Total leucocyte numbers did not differ markedly among the groups. Significant differences were registered when values from control and animals harboring each larval stage of D. hominis were compared; with crescent rank: L1-, L2-, control and L3-infected groups. Leucocyte numbers were significantly higher in the control, 15, 20 or 28 dpi groups than in the 6 dpi animals. Higher counts were observed in control, L2- or L3-infected rats than L1-infected animals. Neutrophils, eosinophils and both large and small lymphocytes were also counted and analyzed. Basophils and monocytes were insufficient in number to permit statistical studies. These results stimulate the continuity of the studies about the host-parasite relationship in the dermatobiosis.


1965 ◽  
Vol 39 (4) ◽  
pp. 363-376 ◽  
Author(s):  
M.F.A. Saoud

In the past two decades, considerable evidence has accumulated in the literature about the differences in the susceptibility of various intermediate hosts of Schistosoma mansoni to different strains of the parasite. Comprehensive studies on this aspect of host-parasite relationship have been published by Files & Cram (1949), Abdel-Malek (1950) and Files (1951). The results of more recent studies have been reported by Wright (1962) and Saoud (1964).In the present paper, the writer has studied the susceptibility of four intermediate hosts of S. mansoni from Brazil, Puerto Rico, Egypt and Tanganyika to some strains of the parasite.


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