scholarly journals Pure-Tone Hearing Thresholds and Brainstem Auditory Evoked Potentials in Sporadic Ataxia

2019 ◽  
Vol 24 (01) ◽  
pp. e86-e92
Author(s):  
Bianca Simone Zeigelboim ◽  
Anylize Wachholz Vom Scheidt ◽  
Kairone Fernandes Kronbauer ◽  
Paulo Breno Noronha Liberalesso ◽  
Maria Renata José ◽  
...  

Abstract Introduction Spinocerebellar ataxia (SCA) is part of a genetic and clinical heterogeneous group of neurodegenerative diseases characterized by progressive cerebellar ataxia. Objective To describe the results of audiological and electrophysiological hearing evaluations in patients with sporadic ataxia (SA). Methods A retrospective cross-sectional study was carried out with 11 patients submitted to the following procedures: anamnesis, otorhinolaryngological evaluation, tonal and vocal audiometry, acoustic immittance and brainstem auditory evoked potential (BAEP) tests. Results The patients presented with a prevalence of gait imbalance, of dysarthria, and of dysphagia; in the audiometric and BAEPs, four patients presented with alterations; in the acoustic immittance test, five patients presented with alterations, predominantly bilateral. Conclusion The most evident alterations in the audiological evaluation were the prevalence of the descending audiometric configuration between the frequencies of 2 and 4 kHz and the absence of the acoustic reflex between the frequencies of 3 and 4 kHz bilaterally. In the electrophysiological evaluation, the patients presented changes with a prevalence of increased I, III and V wave latencies and the interval in the interpeak I-III, I-V and III-V. In the present study, it was observed that auditory complaints did not have a significant prevalence in this type of ataxia, which does not occur in some types of autosomal recessive and dominant ataxia.

2013 ◽  
Vol 1 (2) ◽  
pp. 8-12 ◽  
Author(s):  
Shatdal Chaudhary ◽  
Prahlad Karki ◽  
Kumar Bhupender Bajaj ◽  
Sushila Patel

BACKGROUND:  Brainstem auditory evoked potentials (BAEP) have been used for electrophysiological assessment of central neuropathy in diabetes. However, the role of this test in documenting the abnormality, the site of abnormality and relation of these abnormalities with metabolic control of diabetes are not clear as yet. The present study was done to explore the presence of abnormalities, if any, in the test parameters and relation of these with diabetic status. METHODS:  It was a cross sectional study with controls. Thirty patients of diabetes mellitus (group 1) and thirty healthy controls (group 2) were included in the study. All the patients were subjected to detail clinical history, clinical and neurological examination. Detail laboratory investigation including haemogram, fasting and postprandial plasma sugar (2 hours), HbA1c, urine R/E, 24 hour urine for proteins, ECG, RFT, LFT and lipid profile were done. BAEP was done in all the subjects RESULTS:  Mean peak latency of waves I, III, V and interpeak latency of I-III, III-V, I-V were prolonged in group 1, but were not statistically significant. Abnormal BAEP response was found in 8 patients (27%) in group 1. There was no significant relation between abnormal BAEP response with age, sex, type of diabetes, duration of diabetes since detection, fasting plasma sugar level, postprandial plasma sugar level, glycosylated haemoglobin, presence of retinopathy, nephropathy and peripheral neuropathy. CONCLUSIONS:  BAEP is a useful method for obtaining an early diagnosis of central and cranial nerve abnormalities in diabetic patients.DOI: http://dx.doi.org/10.3126/jucms.v1i2.8403 Journal of Universal College of Medical Sciences Vol.1(2) 2013: 8-12


2018 ◽  
Vol 76 (3) ◽  
pp. 170-176 ◽  
Author(s):  
Bianca Simone Zeigelboim ◽  
Hélio A. G. Teive ◽  
Michèlli Rodrigues da Rosa ◽  
Jéssica Spricigo Malisky ◽  
Vinicius Ribas Fonseca ◽  
...  

ABSTRACT Objective To assess central auditory function in Friedreich's ataxia. Methods A cross-sectional, retrospective study was carried out. Thirty patients underwent the anamnesis, otorhinolaryngology examination, pure tone audiometry, acoustic immittance measures and brainstem auditory evoked potential (BAEP) assessments. Results The observed alterations were: 43.3% in the pure tone audiometry, bilateral in 36.7%; 56.6% in the BAEP test, bilateral in 50%; and 46.6% in the acoustic immittance test. There was a significant difference (p < 0.05) in the comparison between the tests performed. Conclusion In the audiological screening, there was a prevalence of the descending audiometric configuration at the frequency of 4kHz, and absence of the acoustic reflex at the same frequency. In the BAEP test, there was a prevalence of an increase of the latencies in waves I, III and V, and in the intervals of interpeaks I-III, I-V and III-V. In 13.3% of the patients, wave V was absent, and all waves were absent in 3.3% of patients.


Author(s):  
Selhan G¨urkan ◽  
Serpil M. Durankaya ◽  
Basak Mutlu ◽  
Yalc¸ın ˙Isler ◽  
Yig˘it O¨. Uzun ◽  
...  

Background: Deteriorated speech understanding is a common complaint in elderly people, and behavioraltests are used for routine clinical assessment of this problem. Cortical auditory evoked potentials(CAEPs) are frequently used for assessing speech detection and discrimination abilities of the elderly,and give promise for differential diagnosis of speech-understanding problems.<br />Purpose: The aim of the study was to compare the P1, N1, and P2 CAEP latencies and amplitudes inpresbycusis with low and high word recognition score (WRS).<br />Research Design: A cross-sectional study design was used for the study. Two groups were formed fromthe patients with presbycusis based on their scores on the speech-recognition test.<br />Study Sample: Fifty-seven elderly volunteers participated in the study. The first group composed of 27participants with high WRS, the other group composed of 30 participants with low WRS.<br />Data Collection and Analysis: The CAEP waves were recorded from these participants using speech signals.Latencies and amplitudes of P1-N1-P2 waves of the two groups were compared with the t-test statistic.<br />Results: There were significant prolongation of P1 and N1 latencies in presbycusis with low WRS whencompared with presbycusis with a relatively high word score (p < 0.05).<br />Conclusion: According to the result of the research, P1 and N1 latencies of presbycusis with low WRSwere longer than the participants with high WRS. Factors affecting peripheral auditory system, such asstimulus sensation level, might be responsible for P1 and N1 latency prolongation of the low WRS group.<br />


Author(s):  
Puguh Setyo Nugroho ◽  
Nyilo Purnami ◽  
Rosa Falerina ◽  
Rizka Fathoni Perdana ◽  
Yoga Rahmadiyanto ◽  
...  

AbstractNoise can have an impact on hearing loss. Changes in hearing thresholds due to noise are some temporary but others potentially permanent. The impact of hearing loss must be controlled so the quality of life will not decrease. A cross-sectional study to assess the quality and increasing knowledge about noise-induced hearing loss was implemented with lectures, discussions and a pre-test before the activity and a post-test after the activity to assess the knowledge development. The polling was conducted to assess the participants' attitudes and psychomotor skills. The study was followed by 77 participants, most of whom were aged 20-30 years, namely 23 (30%). It was found that 16 people (20%) had complaints of hearing loss, 18 people (24%) often used headsets and earphones, 18 (23%) people worked in noisy places. The average pre-test result was 35.06 (+13.72) and the post-test was 77.9 (+20.81). Comparison of pre-test and post-test results of hearing health education obtained different results (p < 0.0001) significantly. Noise-induced hearing loss is permanent deafness and cannot be treated with medicine or surgery. Prevention is the most important thing from noise-induced hearing loss. The counseling education about noise-induced hearing loss on community must always be performed as an prevention and early detection.Keywords: deafness, noise induce hearing loss, prevention, education AbstrakBising dapat berdampak terhadap gangguan pendengaran. Perubahan batas pendengaran akibat bising yang bersifat sementara, dan perubahan batas pendengaran akibat bising yang bersifat menetap. Dampak gangguan pendengaran harus dikendalikan agar tidak menimbulkan penuruna kualitas kehidupan. Studi cross sectional untuk menilai kualitas dan upaya peningkatan pengetahuan tentang gangguan pednegaran akibat bising dilaksanakan dengan ceramah, diskusi dan dilakukan pre test sebelum kegiatan dan post test setelah kegiatan untuk menilai peningkatan pengetahuan. Survei jajak pendapat dilakukan untuk menilai sikap dan psikomotor peserta. Studi diikuti 77 peserta, usia terbanyak di usia 20 – 30 tahun yaitu 23 orang (30%). Didapatkan 16 orang (20%) mengalami keluhan gangguan pendengaran, 18 orang (24%) sering menggunakan headset dan earphone,18 (23%) orang bekerja di tempat bising.  Hasil rata-rata pre test 35,06  (+13,72) dan rata-rata post test 77,9 (+20,81). Perbandingan hasil pre test dan  post  test  penyuluhan  kesehatan  pendengaran  didapatkan  hasil  yang  berbeda signifikan (p < 0,0001). Tuli akibat bising merupakan tuli yang bersifat menetap dan tidak dapat diobati dengan obat maupun pembedahan, pencegahan merupakan hal yang terpenting dari tuli akibat bising atau noise induced hearing loss.Kegiatan edukasi penyuluhan gangguan pendengaran akibat bising harus senantiasa dilakukan di masyarakat sebagai upaya pencegahan dan deteksi dini.Kata kunci: Tuli, gangguan pendengaran karena bising, pencegahan, edukasi 


Neurosciences ◽  
2015 ◽  
Vol 20 (3) ◽  
pp. 253-258 ◽  
Author(s):  
Sonia Garg ◽  
Rajeev Sharma ◽  
Shilekh Mittal ◽  
Satish Thapar

2017 ◽  
Vol 22 (04) ◽  
pp. 342-347
Author(s):  
Daniela Silva ◽  
Georgea Ribeiro ◽  
Gustavo Castilho ◽  
Jair Mantovani

Introduction For the population with risk factors for hearing loss, the first option to assess the hearing status is the performance of the automated brainstem auditory evoked potential (BAEP) test because of its efficacy in identifying retrocochlear hearing loss. Objective To verify the outcomes of automated BAEP performed in different settings as well as the factors associated with the prevalence of hearing impairment. Methods Cross-sectional study conducted from October of 2014 to May of 2015. The sample consisted of 161 infants with at least one risk factor for hearing loss who underwent automated BAEP during the hospital stay or at the outpatient clinic. After 30 days, the altered cases were referred for BAEP diagnosis. Results One hundred and thirty-eight infants (86%) had a result of “pass” and 23 (14%) of “failure” in the automated BAEP. There was no statistically significant difference in the rate of “referred” results between examinations performed in different settings. The infants' ages did not influence the number of abnormal cases. All of the 23 infants who presented a “referred” result in the automated BAEP, unilateral or bilateral, were sent for BAEP diagnosis, and out of these, 9 (39%) remained with at least some degree of alteration. The average age of diagnosis was 2.7 months. Conclusion The results of the automated BAEP were similar when performed during hospitalization or after discharge. Neither the age at the examination nor the gender of the patient influenced the prevalence of hearing loss.


2020 ◽  
Vol 31 (08) ◽  
pp. 559-565
Author(s):  
Julia Campbell ◽  
Mashhood Nielsen ◽  
Connor Bean ◽  
Alison LaBrec

Abstract Background Sensory gating is a measure used to evaluate inhibitory deficits underlying neurological disorders. However, the effects of hearing loss (HL), thought to decrease inhibition, remain unknown on gating function. Purpose The goal of this study was to investigate gating performance in HL. Research Design This was a prospective, cross-sectional study with independent group comparison and correlational design. Study Sample Eleven adults (mean age/standard deviation = 47.546 ± 7.967 years) with normal hearing (NH) and 11 adults (mean age/standard deviation = 56.273 ± 13.871 years) with mild–moderate high-frequency HL. Data Collection and Analysis Cortical auditory evoked potentials (CAEPs) were recorded in response to tonal pairs via high-density electroencephalography. The CAEP response to the second tone in the pair (S2) was compared with the response to the first tone in the pair (S1) within groups. Amplitude gating indices were compared between groups and correlated with auditory behavioral measures. Current density reconstructions were performed to estimate cortical gating generators. Results Amplitude gating indices were decreased and correlated with elevated auditory thresholds. Gating generators in temporal, frontal, and prefrontal regions were localized in the NH group, while HL gating was localized in mainly temporal and parietal areas. Conclusions Reduced inhibition may be associated with compensatory cortical gating networks in HL and should be considered when utilizing gating in clinical populations.


Author(s):  
Geetanjali Sharma

Aims/ Objectives: To study the importance of electrophysiological tests in diagnosing hereditary motor sensory neuropathy in absence of genetic studies. Study Design: Cross-sectional study. Place and Duration of Study: Department of Physiology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India. Methodology: The patients were referred from the Department of Medicine to the Department of Physiology for nerve conduction, F-wave, EMG, VEP & BERA studies. Results: On electrophysiological examination, there was symmetrical decreased motor conduction velocity of median nerve (less than 38 m/sec), ulnar, tibial and peroneal nerves except in the first patient where the left peroneal nerve conduction velocity was not recordable with decreased amplitude and increased distal motor latencies. Sensory conduction velocities for bilateral median nerves were also decreased with increased latency and decreased amplitude in both the patients. Sensory conduction velocity and amplitudes of bilateral sural nerves were decreased in the first patient with increased latencies. However, sensory conduction velocity wasn’t recordable for bilateral sural nerves in the other patient. EMG shows decrease in recruitment of motor unit potentials, amplitude in bilateral tibial, peroneous, abductor digiti minimi & 1st dorsal interosseus muscle in the first patient. In proximal upper & lower limb muscles, EMG showed features of denervation. In the second patient, EMG was not advised. VEP in one patient had increased latency of P100 wave & other had normal VEP. Brainstem auditory evoked potential was normal in both patients. Conclusion: The paper highlights the importance of electrophysiological studies in diagnosis of motor sensory neuropathy in absence of genetic studies. Marked slowing of conduction velocity is the hallmark of CMDT1 [demylinating type].


Author(s):  
Krystin Carlson ◽  
Niladri Basu ◽  
Julius Fobil ◽  
Richard Neitzel

Metals, such as lead, may be ototoxic, but this property is not well understood, especially in conjunction with noise. This cross-sectional study investigated hearing, noise, and metal biomarkers in informal electronic waste (e-waste) recycling workers in Accra, Ghana. Workers (N = 58) participated in audiometric testing, a survey, blood collection, and personal noise dosimetry. Sixty percent of participants displayed audiometric notches indicative of noise-induced hearing loss (NIHL). Most workers (86%) reported high noise while working. Daily average noise levels were in the range 74.4–90.0 dBA. Linear regression models indicated participants who lived at Agbogbloshie Market for longer periods were significantly associated with worse hearing thresholds at 4 and 6 kHz. The models did not identify blood levels of lead, mercury, or cadmium as significant predictors of worse hearing thresholds or larger noise notches, but increased levels of selenium were significantly associated with better hearing at 6 kHz. Models of thresholds at 4 and 6 kHz were improved by including an interaction term between the maximum noise exposure and the level of zinc in whole blood, suggesting that zinc may protect hearing at lower noise levels, but not at higher levels. Further study of the relationships between elements, noise, and NIHL is needed.


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