3D MRI in Musculoskeletal Oncology

2021 ◽  
Vol 25 (03) ◽  
pp. 418-424
Author(s):  
Blake C. Jones ◽  
Shivani Ahlawat ◽  
Laura M. Fayad
Keyword(s):  
Tumor Imaging ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Motion Artifact ◽  
Whole Body ◽  
Acquisition Time ◽  
3D Mri ◽  
Isotropic Resolution ◽  
3D Acquisition ◽  
Magnetic Resonance Imaging Mri

AbstractAdvances in magnetic resonance imaging (MRI) technology now enable the feasible three-dimensional (3D) acquisition of images. With respect to the imaging of musculoskeletal (MSK) tumors, literature is beginning to accumulate on the use of 3D MRI acquisition for tumor detection and characterization. The benefits of 3D MRI, including general advantages, such as decreased acquisition time, isotropic resolution, and increased image quality, are not only inherently useful for tumor imaging, but they also contribute to the feasibility of more specialized tumor-imaging techniques, such as whole-body MRI, and are reviewed here. Disadvantages of 3D acquisition, such as motion artifact and equipment requirements, do exist and are also discussed. Although further study is needed, 3D MRI acquisition will likely prove increasingly useful in the evaluation of patients with tumors of the MSK system.

3D MRI of the Knee

2021 ◽  
Vol 25 (03) ◽  
pp. 455-467
Author(s):  
Faysal Altahawi ◽  
Jason Pierce ◽  
Mercan Aslan ◽  
Xiaojuan Li ◽  
Carl S. Winalski ◽  
...  
Keyword(s):  
Imaging Techniques ◽  
Spin Echo ◽  
Three Dimensional ◽  
Volume Averaging ◽  
Fast Spin Echo ◽  
3D Mri ◽  
Multiplanar Reconstructions ◽  
Out Of Plane ◽  
Magnetic Resonance Imaging Mri ◽  
3D Sequences

AbstractThree-dimensional (3D) magnetic resonance imaging (MRI) of the knee is widely used in musculoskeletal (MSK) imaging. Currently, 3D sequences are most commonly used for morphological imaging. Isotropic 3D MRI provides higher out-of-plane resolution than standard two-dimensional (2D) MRI, leading to reduced partial volume averaging artifacts and allowing for multiplanar reconstructions in any plane with any thickness from a single high-resolution isotropic acquisition. Specifically, isotropic 3D fast spin-echo imaging, with options for tissue weighting similar to those used in multiplanar 2D FSE imaging, is of particular interest to MSK radiologists. New applications for 3D spatially encoded sequences are also increasingly available for clinical use. These applications offer advantages over standard 2D techniques for metal artifact reduction, quantitative cartilage imaging, nerve imaging, and bone shape analysis. Emerging fast imaging techniques can be used to overcome the long acquisition times that have limited the adoption of 3D imaging in clinical protocols.

Immunszintigraphie mit 111ln-DTPA-markierten monoklonalen Antikörpern: Vergleich zwischen ECT und planarer Szintigraphie

1987 ◽  
Vol 26 (06) ◽  
pp. 258-262
Author(s):  
J. Happi ◽  
R. P. Baum ◽  
J. Frohn ◽  
B. Weimer ◽  
A. Halbsguth ◽  
...  
Keyword(s):  
Imaging Techniques ◽  
Diagnostic Procedures ◽  
Undifferentiated Carcinoma ◽  
Whole Body ◽  
Acquisition Time ◽  
Planar Imaging ◽  
Primary Tumors ◽  
Intraindividual Comparison ◽  
Single Detector ◽  
Increased Sensitivity

The present study was done in order to examine if the use of111ln-DTPA- labeled MAb fragments in place of 131l-labeled MAb fragments increases the sensitivity of tomographic immunoscintigraphy to reach the level of that of planar imaging techniques. In 11 patients with various primary tumors, local recurrences or metastases [colorectal carcinoma (n = 7), ovarian carcinoma (n = 2), papillary thyroid carcinoma (n = 1), undifferentiated carcinoma of the lung (n = 1)], immunoscintigraphy (IS) was carried out using 111ln-DTPA- labeled F(ab’)2 fragments of various MAbs (anti-CEA, OC 125, anti-hTG) and planar and tomographic imaging were compared intraindividually. By conventional diagnostic procedures, the presence of a tumor mass was confirmed (transmission computer tomography, ultrasound) or verified (131l whole-body scintigraphy, histology) in all cases. Immunoscintigraphy was positive in 9 out of 11 cases by ECT and in 10 out of 11 cases by planar imaging. When using 111 In-labeled MAb fragments, intraindividual comparison of ECT and planar imaging resulted in a similar sensitivity. The increased sensitivity of ECT using this tracer in contrast to 131l-labeled MAb fragments may be attributed to the fact that the physical properties of111 In are much more suitable for the gamma cameras most commonly used (single detector, 3/8” crystal); using 111 In-labeled MAb fragments, count rates sufficient for ECT can be obtained within a reasonable acquisition time. This allows to combine IS with the advantages of ECT regarding tumour localization and prevention of artefacts due to superposition of background.

scholarly journals Evaluation of Nonradiative Clinical Imaging Techniques for the Longitudinal Assessment of Tumour Growth in Murine CT26 Colon Carcinoma

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Johanne Seguin ◽  
Bich-Thuy Doan ◽  
Heldmuth Latorre Ossa ◽  
Lauriane Jugé ◽  
Jean-Luc Gennisson ◽  
...  
Keyword(s):  
Colon Carcinoma ◽  
Tumour Growth ◽  
Imaging Techniques ◽  
Acquisition Time ◽  
Longitudinal Assessment ◽  
Resonance Imaging ◽  
Orthotopic Model ◽  
Short Acquisition Time ◽  
Magnetic Resonance Imaging Mri ◽  
Good Delineation

Background and Objectives. To determine the most appropriate technique for tumour followup in experimental therapeutics, we compared ultrasound (US) and magnetic resonance imaging (MRI) to characterize ectopic and orthotopic colon carcinoma models. Methods. CT26 tumours were implanted subcutaneously (s.c.) in Balb/c mice for the ectopic model or into the caecum for the orthotopic model. Tumours were evaluated by histology, spectrofluorescence, MRI, and US. Results. Histology of CT26 tumour showed homogeneously dispersed cancer cells and blood vessels. The visualization of the vascular network using labelled albumin showed that CT26 tumours were highly vascularized and disorganized. MRI allowed high-resolution and accurate 3D tumour measurements and provided additional anatomical and functional information. Noninvasive US imaging allowed good delineation of tumours despite an hypoechogenic signal. Monitoring of tumour growth with US could be accomplished as early as 5 days after implantation with a shorter acquisition time (<5 min) compared to MRI. Conclusion. MRI and US afforded excellent noninvasive imaging techniques to accurately follow tumour growth of ectopic and orthotopic CT26 tumours. These two techniques can be appropriately used for tumour treatment followup, with a preference for US imaging, due to its short acquisition time and simplicity of use.

Conventional and Arthrographic Magnetic Resonance Techniques for Hip Evaluation: What the Radiologist Should Know

2019 ◽  
Vol 23 (03) ◽  
pp. 227-251 ◽  
Author(s):  
Florian Schmaranzer ◽  
Luis Cerezal ◽  
Eva Llopis
Keyword(s):  
Magnetic Resonance ◽  
Sports Injuries ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Pain Syndrome ◽  
Volumetric Analysis ◽  
Computer Assisted ◽  
Current Standard ◽  
Increasing Demand ◽  
Magnetic Resonance Imaging Mri

AbstractOver the last 2 decades, the definition of pathomechanical concepts that link osseous deformities to chondrolabral damage and expose young and active patients to the risk of early osteoarthritis has led to a tremendous increase in the number of joint-preserving surgeries performed. The rise in arthroscopic procedures has led to an increasing demand for comprehensive preoperative magnetic resonance imaging (MRI) assessment of the hip joint. This includes conventional MRI for the assessment of extra-articular and periarticular pathologies such as greater trochanteric pain, deep gluteal pain syndrome, and sports injuries. Magnetic resonance arthrography with or without traction is reserved for the accurate evaluation of deformities associated with impingement and hip instability and for detecting the resulting intra-articular lesions. This article summarizes the current standard imaging techniques that the radiologist should know. It also explores the potential of computer-assisted analysis of three-dimensional MRI for virtual impingement simulation and volumetric analysis of cartilage composition and geometry.

scholarly journals Fully Automatic Knee Bone Detection and Segmentation on Three-Dimensional MRI

Diagnostics ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 123
Author(s):  
Rania Almajalid ◽  
Ming Zhang ◽  
Juan Shan
Keyword(s):  
Bone Structure ◽  
Three Dimensional ◽  
Training Data ◽  
3D Mri ◽  
Detection Model ◽  
Biological Images ◽  
Medical Sector ◽  
Fully Automatic ◽  
Magnetic Resonance Imaging Mri ◽  
Bone Structures

In the medical sector, three-dimensional (3D) images are commonly used like computed tomography (CT) and magnetic resonance imaging (MRI). The 3D MRI is a non-invasive method of studying the soft-tissue structures in a knee joint for osteoarthritis studies. It can greatly improve the accuracy of segmenting structures such as cartilage, bone marrow lesion, and meniscus by identifying the bone structure first. U-net is a convolutional neural network that was originally designed to segment the biological images with limited training data. The input of the original U-net is a single 2D image and the output is a binary 2D image. In this study, we modified the U-net model to identify the knee bone structures using 3D MRI, which is a sequence of 2D slices. A fully automatic model has been proposed to detect and segment knee bones. The proposed model was trained, tested, and validated using 99 knee MRI cases where each case consists of 160 2D slices for a single knee scan. To evaluate the model’s performance, the similarity, dice coefficient (DICE), and area error metrics were calculated. Separate models were trained using different knee bone components including tibia, femur, patella, as well as a combined model for segmenting all the knee bones. Using the whole MRI sequence (160 slices), the method was able to detect the beginning and ending bone slices first, and then segment the bone structures for all the slices in between. On the testing set, the detection model accomplished 98.79% accuracy and the segmentation model achieved DICE 96.94% and similarity 93.98%. The proposed method outperforms several state-of-the-art methods, i.e., it outperforms U-net by 3.68%, SegNet by 14.45%, and FCN-8 by 2.34%, in terms of DICE score using the same dataset.

3D MRI of the Hip Joint: Technical Considerations, Advantages, Applications, and Current Perspectives

2021 ◽  
Vol 25 (03) ◽  
pp. 488-500
Author(s):  
Oganes Ashikyan ◽  
Joel Wells ◽  
Avneesh Chhabra
Keyword(s):  
Acetabular Dysplasia ◽  
Three Dimensional ◽  
Resonance Imaging ◽  
3D Mri ◽  
Great Precision ◽  
Conventional Mri ◽  
Labral Tears ◽  
Technical Details ◽  
Magnetic Resonance Imaging Mri ◽  
Technical Considerations

AbstractMagnetic resonance imaging (MRI) is a common choice among various imaging modalities for the evaluation of hip conditions. Conventional MRI with two-dimensional acquisitions requires a significant amount of time and is limited by partial-volume artifacts and suboptimal fluid-to-cartilage contrast. Recent hardware and software advances have resulted in development of novel isotropic three-dimensional (3D) single-acquisition protocols that cover the volume of the entire hip and can be reconstructed in arbitrary planes for submillimeter assessment of bony and labro-cartilaginous structures in their planes of orientation. This technique facilitates superior identification of small labral tears and other hip lesions with better correlations with arthroscopy. In this review, we discuss technical details related to 3D MRI of the hip, its advantages, and its role in commonly encountered painful conditions that can be evaluated with great precision using this technology. The entities described are femoroacetabular impingement with acetabular labral tears, acetabular dysplasia, avascular necrosis, regional tendinopathies and tendon tears, bursitis, and other conditions.

Osteochondral Lesions of the Talus

2010 ◽  
Vol 100 (3) ◽  
pp. 189-194 ◽  
Author(s):  
Da-Peng Hao ◽  
Jian-Zhong Zhang ◽  
Zhen-Chang Wang ◽  
Wen-Jian Xu ◽  
Ji-Hua Liu ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Cartilage Defects ◽  
Osteochondral Lesions ◽  
Talar Dome ◽  
Conventional Mri ◽  
Arthroscopic Findings ◽  
Magnetic Resonance Imaging Mri ◽  
Sensitivity Specificity

Background: Conventional magnetic resonance imaging (MRI) has been demonstrated to be a valuable tool in diagnosing osteochondral lesions of the talus. No previous study, to our knowledge, has evaluated the diagnostic ability of fat-suppressed fast spoiled gradient-echo (FSPGR) MRI in osteochondral lesions of the talus. We sought to compare three-dimensional fat-suppressed FSPGR MRI with conventional MRI in diagnosing osteochondral lesions of the talus. Methods: Thirty-two consecutive patients with clinically suspected cartilage lesions undergoing three-dimensional fat-suppressed FSPGR MRI and conventional MRI were assessed. Sensitivity, specificity, and accuracy of diagnosis were determined using arthroscopic findings as the standard of reference for the different imaging techniques. The location of the lesion on the talar dome was recorded on a nine-zone anatomical grid on MRIs. Results: Arthroscopy revealed 21 patients with hyaline cartilage defects and 11 with normal ankle joints. The sensitivity, specificity, and accuracy of the two methods for detecting articular cartilage defect were 62%, 100%, and 75%, respectively, for conventional MRI and 91%, 100%, and 94% for three-dimensional fat-suppressed FSPGR MRI. Sensitivity and accuracy were significantly higher for FSPGR imaging than for conventional MRI (P &lt; .05), but there was no difference in specificity between these two methods. According to the nine-zone anatomical grid, the area most frequently involved was the middle of the medial talar dome (16 lesions, 76%). Conclusions: T1-weighted three-dimensional fat-suppressed FSPGR MRI is more sensitive than is conventional MRI in detecting defects of articular cartilage covering osteochondral lesions of the talus. (J Am Podiatr Med Assoc 100(3): 189–194, 2010)

Quantitative Musculoskeletal Tumor Imaging

2020 ◽  
Vol 24 (04) ◽  
pp. 428-440
Author(s):  
B Matthew Howe ◽  
Stephen M. Broski ◽  
Laurel A. Littrell ◽  
Kay M. Pepin ◽  
Doris E. Wenger
Keyword(s):  
Tumor Imaging ◽  
Three Dimensional ◽  
Musculoskeletal Tumor ◽  
Dynamic Contrast Enhancement ◽  
Three Dimensional Printing ◽  
Musculoskeletal Tumors ◽  
Quantitative Pet ◽  
Positron Emission ◽  
Pet Ct ◽  
Magnetic Resonance Imaging Mri

AbstractThe role of quantitative magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) techniques continues to grow and evolve in the evaluation of musculoskeletal tumors. In this review we discuss the MRI quantitative techniques of volumetric measurement, chemical shift imaging, diffusion-weighted imaging, elastography, spectroscopy, and dynamic contrast enhancement. We also review quantitative PET techniques in the evaluation of musculoskeletal tumors, as well as virtual surgical planning and three-dimensional printing.

scholarly journals Illuminating the Brain With X-Rays: Contributions and Future Perspectives of High-Resolution Microtomography to Neuroscience

2021 ◽  
Vol 15 ◽  
Author(s):  
Paulla Vieira Rodrigues ◽  
Katiane Tostes ◽  
Beatriz Pelegrini Bosque ◽  
João Vitor Pereira de Godoy ◽  
Dionisio Pedro Amorim Neto ◽  
...  
Keyword(s):  
Imaging Techniques ◽  
Three Dimensional ◽  
X Rays ◽  
Future Perspectives ◽  
Resonance Imaging ◽  
X Ray ◽  
Cellular Resolution ◽  
Magnetic Resonance Imaging Mri ◽  
Non Destructive ◽  
The Brain

The assessment of three-dimensional (3D) brain cytoarchitecture at a cellular resolution remains a great challenge in the field of neuroscience and constant development of imaging techniques has become crucial, particularly when it comes to offering direct and clear obtention of data from macro to nano scales. Magnetic resonance imaging (MRI) and electron or optical microscopy, although valuable, still face some issues such as the lack of contrast and extensive sample preparation protocols. In this context, x-ray microtomography (μCT) has become a promising non-destructive tool for imaging a broad range of samples, from dense materials to soft biological specimens. It is a new supplemental method to be explored for deciphering the cytoarchitecture and connectivity of the brain. This review aims to bring together published works using x-ray μCT in neurobiology in order to discuss the achievements made so far and the future of this technique for neuroscience.

Sign in / Sign up

Export Citation Format

Share Document