Can Nanoparticles in Homeopathic Remedies Enhance Phototherapy of Cancer? A Hypothetical Model

Homeopathy ◽  
2021 ◽  
Author(s):  
Ayesha Loonat ◽  
Janice Pellow ◽  
Heidi Abrahamse ◽  
Rahul Chandran

AbstractThe continuous rise in cancer incidence places a massive burden on the health sector to increase efforts in the fight against cancer. As a holistic complementary medicine modality, homeopathy has the potential to assist in the supportive and palliative treatment of cancer patients. Recent empirical studies demonstrate the presence of silica and original source nanoparticles in ultra-high dilutions of several homeopathic medicines. Recent studies have also demonstrated the efficacy of phototherapy in inducing the ablation of cancer cells through laser-activated nanoparticle photosensitizers. A new hypothetical research model is presented herein, in an attempt to investigate and compare the phototherapeutic effects of homeopathic source nanoparticles with photosensitizing nanoparticle agents that have previously been tested.

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Lindi van Niekerk ◽  
Lenore Manderson ◽  
Dina Balabanova

Abstract Background Social innovation has been applied increasingly to achieve social goals, including improved healthcare delivery, despite a lack of conceptual clarity and consensus on its definition. Beyond its tangible artefacts to address societal and structural needs, social innovation can best be understood as innovation in social relations, in power dynamics and in governance transformations, and may include institutional and systems transformations. Methods A scoping review was conducted of empirical studies published in the past 10 years, to identify how social innovation in healthcare has been applied, the enablers and barriers affecting its operation, and gaps in the current literature. A number of disciplinary databases were searched between April and June 2020, including Academic Source Complete, CIHAHL, Business Source Complete Psych INFO, PubMed and Global Health. A 10-year publication time frame was selected and articles limited to English text. Studies for final inclusion was based on a pre-defined criteria. Results Of the 27 studies included in this review, the majority adopted a case research methodology. Half of these were from authors outside the health sector working in high-income countries (HIC). Social innovation was seen to provide creative solutions to address barriers associated with access and cost of care in both low- and middle-income countries and HIC settings in a variety of disease focus areas. Compared to studies in other disciplines, health researchers applied social innovation mainly from an instrumental and technocratic standpoint to foster greater patient and beneficiary participation in health programmes. No empirical evidence was presented on whether this process leads to empowerment, and social innovation was not presented as transformative. The studies provided practical insights on how implementing social innovation in health systems and practice can be enhanced. Conclusions Based on theoretical literature, social innovation has the potential to mobilise institutional and systems change, yet research in health has not yet fully explored this dimension. Thus far, social innovation has been applied to extend population and financial coverage, principles inherent in universal health coverage and central to SDG 3.8. However, limitations exist in conceptualising social innovation and applying its theoretical and multidisciplinary underpinnings in health research. Graphic abstract


BMC Cancer ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Joachim Wiskemann ◽  
Simone Hummler ◽  
Christina Diepold ◽  
Melanie Keil ◽  
Ulrich Abel ◽  
...  

2018 ◽  
Vol 14 (1) ◽  
pp. 60-70 ◽  
Author(s):  
Rosemary Lysaght ◽  
Michael J. Roy ◽  
Jack S. Rendall ◽  
Terry Krupa ◽  
Liam Ball ◽  
...  

Purpose The aim of this exploratory, mixed methods study was to develop and test a tool that identifies foundational dimensions of work integration social enterprises (WISEs) for use in empirical studies and enterprise self-assessment. Construction of the initial prototype was based upon a review of the literature and prior qualitative research by the authors. Design/methodology/approach A 20-item question pool with a four-point response scale was constructed to explore WISE business and employment practices and strategies for worker growth and development. Three sequential field tests were conducted with the prototype – the first with 5 Canadian WISEs, the second with 14 WISEs in the UK and the third with 6 Canadian WISEs involved in an outcome study in the mental health sector. Each field test included completion of the questionnaire by persons with managerial responsibility within the WISE and evaluative feedback captured through questions on the applicability and interpretability of the items. Findings Testing of the prototype instrument revealed the inherent diversity in the field and the difficulty in creating questions that both embrace that diversity and produce unidimensional variables definable along a spectrum. A number of challenges with question structure were identified and have been modified throughout the iterative testing process. Research limitations/implications This study identified central domains for inclusion in a multi-dimensional WISE assessment tool. Further testing will help further refine scaling and establish psychometric properties. Originality/value This measure will provide a descriptive profile of WISEs across sectors and identify WISE core dimensions for research and organizational development.


2018 ◽  
Vol 27 (1) ◽  
pp. 38-43
Author(s):  
MK Sarker ◽  
MM Sarker ◽  
MFK Bhuiyan ◽  
MMR Khan ◽  
ASMA Raihan

Oesophageal cancer is a gastrointestinal malignancy with insidious onset and poor prognosis. The disease predominantly affects the older age groups with pick incidence between 60 to 70 years of age. The total number of oesophageal cancer patients available for the study within the stipulated time was 43. Among them 60.47% patients were male and 39.53% patients were female, 06.98% belonged to age group 31-40, 16.28% belonged to age group 41-50, 37.21% belonged to age group 51-60, 23.25% belonged to age group 61-70 and 16.28% patients were >70 years of age. Mean age was 59.95 years ± 12.63 SD. In our study, 33.3% survived ≤3 months, 09.1% 4–6 months, 15.2 % 7–9 months, 06.1% 10–12 months, 27.2% 13–24 months and 09.1% >24 months. Among the expired patients, 09.10% got curative treatment and rest of 90.90% got palliative treatment. Those who got curative treatment 66.7% survived 13–24 months and 33.3% > 24 months. Those who got palliative treatment 36.7% survived ≤3 months, 10.0% 4–6 months, 06.7% 10–12 months and 30.0% 13–24 months. Overall median survival was 08 months, for curative treatment 18 months and for palliative treatment 07 months.TAJ 2014; 27(1): 38-43


2017 ◽  
Vol 18 (3) ◽  
pp. 195-209 ◽  
Author(s):  
Adel Alferaih

While a number of studies have reviewed empirical research on individuals’ entrepreneurial intentions (EIs), very little is known about the cumulative performance of frequently used constructs and their direct and indirect relationships with EI. This research has exposed 123 usable empirical studies of EI to weight- and meta-analyses to determine the cumulative performance of various frequently explored relationships. A generic research model of the antecedents of EI is proposed on that basis. The outcomes of this research and its limitations have practical and theoretical implications for future entrepreneurship research.


2005 ◽  
Vol 23 (16_suppl) ◽  
pp. 2592-2592 ◽  
Author(s):  
R. I. Dave ◽  
S. V. Shah ◽  
K. M. Patel ◽  
U. B. Tripathi ◽  
A. S. Kapadia ◽  
...  

2020 ◽  
Vol 23 (1) ◽  
Author(s):  
Sylvia Rita Da Rosa ◽  
Federico Gabriel Gómez

This paper presents a research model in didactics of programming elaborated within the theoretical framework of the epistemological theory of Jean Piaget. That theory explains the construction of scientific knowledge based on empirical studies made by Piaget over many years. The model arises from the analysis of the results of the application of principles of the theory, especially the triad of intra-inter-trans stages, to the empirical study of the construction of the concepts of algorithm, data structure and program. The elaboration of the model is a contribution to the development of the didactics of programming and, in general, of the didactics of computer science, since the model can be used in other computer science topics. Didactics is a specific area within computer science, with its own foundations and methods, which studies in depth topics related to education in the discipline. Two empirical studies about the construction of knowledge of algorithms and data structures, and of the corresponding programs as executable objects, are briefly described to illustrate the model.Both examples use a search algorithm (binary and linear) and the implementations are in the programming language C.


2021 ◽  
Author(s):  
xinghe liao ◽  
Cihang Bao ◽  
Minghui Liu ◽  
Menglei Chen ◽  
Xiaoli Gu ◽  
...  

Abstract Background: Hemoglobin is a prognostic factor for many cancer patients. However, its effect on the prognosis of patients with advanced cancer receiving palliative treatment is still unclear.Objective: The aim of this study was to assess whether hemoglobin can be used as a prognostic indicator for patients with advanced cancer receiving palliative treatment.Methods: From July 2013 to October 2015, 368 consecutive patients were treated in the palliative treatment center of the Shanghai Cancer Center of Fudan University. The data for 105 patients were extended in the follow-up. The cut-off value selected for hemoglobin was 100 g/L.Results: The median survival time of patients with low hemoglobin was shorter than that of patients with high hemoglobin (41 days vs. 84 days). In the follow-up readmission cohort (n = 105), the median survival time for patients with high hemoglobin (HHb → HHb) was 3.44 times longer than that of patients with low hemoglobin (HHb → LHb). Thus, both low hemoglobin and decreased hemoglobin were identified as independent prognostic factors for poor prognosis.Conclusions: In palliative treatment, hemoglobin can be used as a stratification factor to determine the prognosis of advanced cancer patients.


Sign in / Sign up

Export Citation Format

Share Document