Liposomal formulations of Alkanna tinctoria root extracts for dermal applications

2021 ◽  
Author(s):  
Antigoni E. Koletti ◽  
Konstantinos N. Kontogiannopoulos ◽  
Konstantinos Gardikis ◽  
Sophia Letsiou ◽  
Vassilios P. Papageorgiou ◽  
...  
Keyword(s):  
Root Extracts ◽  
Liposomal Formulations ◽  
Alkanna Tinctoria

Phenolic profile and antioxidant activity of buckwheat (Fagopyrum esculentum) herb and root extracts

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
D Orcic ◽  
E Svirčev ◽  
N Mimica-Dukic ◽  
I Beara ◽  
K Balog ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Fagopyrum Esculentum ◽  
Phenolic Profile ◽  
Root Extracts

Formulation and Evaluation of Carbopol Gel Containing Liposomes of Ketoconazole. (Part-II)

2009 ◽  
Vol 1 (2) ◽  
Author(s):  
Rakesh Patel ◽  
Hardik Patel ◽  
Ashok Baria
Keyword(s):  
Antifungal Activity ◽  
Rat Skin ◽  
Albino Rat ◽  
In Vitro Drug Release ◽  
Carbopol Gel ◽  
Liposomal Formulations ◽  
Release Drug ◽  
In Vitro Permeation ◽  
In Vitro Antifungal Activity

The aim of this work was to prepare and evaluate the topical carbopol gel formulation containing ketoconazole encapsulated liposomes. Ketoconazole loaded liposomes were prepared by thin film hydration technique. The prepared liposomes were incorporated into 1% carbopol gel, and the systems were evaluated for in-vitro drug release, drug retention into skin and in-vitro antifungal activity. The in-vitro permeation of ketoconazole using wistar albino rat skin from liposomal gel was compared with that of plain drug gel and also with plain drug cream containing 2% w/w of ketoconazole. The release of ketoconazole from liposomal gel was much slower than from non liposomal formulations. Gel containing liposomal ketoconazole showed maximum antifungal activity after 30 hours over plain ketoconazole gel and cream formulations.

Invivo Activity of Polyherbal Gels Prepared Using Carbopol

2020 ◽  
Vol 10 (3) ◽  
pp. 63-66
Author(s):  
Parasakthi N ◽  
Deepika R ◽  
Sivanathan C ◽  
Abubackkar Sithiq PD ◽  
Venkateshan N
Keyword(s):  
Physiological Stress ◽  
Defense Responses ◽  
The Body ◽  
Peptic Ulcers ◽  
Onset Of Action ◽  
Standard Drug ◽  
Root Extracts ◽  
Carbopol 940 ◽  
Anti Inflammatory ◽  
Rich Countries

Pain and inflammation are the basic defense responses of the body that the result of the injury and any other damage to the body. During the years the concerns were raised towards the inflammation that is caused to the oxidative damage that is resulted in the physiological stress due to oxidation. There are a lot of drugs that are used to treat the condition effectively and the typical examples are NSAID’s and SAID’s which have a noted mechanism to show the anti-inflammatory activity. They have serious problems with the side effects like Gastrointestinal irritation, Gastric pain, Gastric perforations and peptic ulcers. Herbs have been used as better alternatives that are used to treat diseases. The significance of the medicinal plants had been emphasized significantly in tradition rich countries like India and all over the world. The research proof of those herbs for their activities and their traditional claims were proven. Poly Herbal Gels were prepared using the root extracts of the plant Corchorus olitorius. The gels were prepared using the Carbopol 940 and the prepared gels were investigated for their anti-inflammatory property and the gels showed a significantly better activity compared to the plant extract and the standard drug too. The addition of other drugs in to the gels added and advantage to the increase in the activity and faster onset of action as the gel was applied directly in the place of the inflammation.

Antipyretic Activity of the Root Extracts of Xylocarpus

2019 ◽  
Vol 9 (3) ◽  
pp. 35-38
Author(s):  
Ganesh Kumar Y ◽  
Pranitha D ◽  
Phaneendra D ◽  
Madhava Reddy Ch
Keyword(s):  
Mechanisms Of Action ◽  
Prostaglandin Synthesis ◽  
The Body ◽  
Human Race ◽  
Pharmacological Activities ◽  
Standard Drug ◽  
Root Extracts ◽  
Antipyretic Activity ◽  
Inhibition Of Prostaglandin Synthesis ◽  
Elevated Body Temperature

Various types of conditions exist in the body that causes fever and pain. Drugs that are used to treat fever are called antipyretics, and those are usually prescribed to treat elevated body temperature. But those drugs result in many other side effects like ulcers, perforations, bleedings and obstructions, which make their use questionable and limiting. Medicinal plants are used in the treatment of diseases from the starting of the human race and the process; they had been subjected to rigorous investigations and tests to establish a scientific proof and validation of the various pharmacological activities and their respective mechanisms of action in treating the herbs. Considering the anti-inflammatory properties of the plant, Xylocarpus mekongesis was investigated for its antipyretic activity in yeast method and 3doses out of which 00mg/kg body weight showed a better activity compared to the standard drug and other extracts too. The mechanism of action was similar to the paracetamol action that is inhibition of prostaglandin synthesis.

Antipyretic activity of the root extracts of Desmodium Gangeticum

2018 ◽  
Vol 8 (2) ◽  
pp. 20-23
Author(s):  
Raja Sheker K ◽  
Naveen B ◽  
Anil kumar A ◽  
Abhilash G
Keyword(s):  
Gastric Ulcers ◽  
Plant Leaves ◽  
Medical Systems ◽  
Human Race ◽  
Standard Drug ◽  
Root Extracts ◽  
Antipyretic Activity ◽  
Scientific Investigations ◽  
And Control ◽  
Effective Drugs

Fevers are considered as the most important parameters to evaluate and diagnose most of the disease conditions like inflammations, wounds and other infections. There are effective drugs that treat and control the fevers out of which NSAID's are most important ones. They cause notable side effects like gastric ulcers, gastric mucosal perforations etc. which make the use of those drugs limited. Herbs are used to treat various diseases, starting from the evolution of the human race. During this, herbs had been introduced to many types of tests and scientific investigations to prove the activities that herbs possess. The diseases that the herbs are used for are notable in the medical systems like Ayurveda and other systems. The need for the validation of the activities of the herbs and medicinal plants is utmost important these days. The extracts of the plant leaves of Desmodium gangeticum were extracted with ethanol and then investigated for the antipyretic activity in yeast induced pyretic method. The extract was tested in two doses 200 and 400mg/kg. This was found significant when compared to the standard drug.

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