Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature

Abstract Background and study aims We report a case of amelanotic malignant melanoma of the esophagus (AMME), an exceedingly rare disease. A 77-year-old Japanese woman presented to our hospital with features suggestive of a middle esophageal submucosal tumor, which was diagnosed pathologically as AMME. The patient underwent thoracoscopic resection of the esophagus and laparoscopic gastric tube reconstruction. Three years after surgery, computed tomography showed no recurrence. Generally, the prognosis of malignant melanoma of the esophagus is very poor. However, our patient had no recurrence, and is alive 3 years after surgery and 5 years after the tumor was first detected.

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Amelanotic Malignant Melanoma of the Esophagus: Case Report and Review of the Literature

Japanese Journal of Clinical Oncology ◽

10.1093/oxfordjournals.jjco.a039402 ◽

1990 ◽

Keyword(s):

Case Report ◽

Malignant Melanoma ◽

Review Of The Literature ◽

Amelanotic Malignant Melanoma

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Amelanotic Malignant Melanoma of Unknown Primary Origin Metastasizing to the Bone Marrow: A Case Report and Review of the Literature

Internal Medicine ◽

10.2169/internalmedicine.53.1412 ◽

2014 ◽

Vol 53 (4) ◽

pp. 325-328 ◽

Cited By ~ 5

Author(s):

Tomotaka Suzuki ◽

Shigeru Kusumoto ◽

Shinsuke Iida ◽

Toyohiro Tada ◽

Fumiko Mori

Keyword(s):

Bone Marrow ◽

Case Report ◽

Malignant Melanoma ◽

Unknown Primary ◽

Review Of The Literature ◽

Amelanotic Malignant Melanoma ◽

Primary Origin ◽

Unknown Primary Origin

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Dermoscopic Features of Pigmented Bowen's Disease in a Japanese Female Mimicking Malignant Melanoma

Dermatology Research and Practice ◽

10.1155/2010/543091 ◽

2010 ◽

Vol 2010 ◽

pp. 1-3 ◽

Cited By ~ 8

Author(s):

Takayuki Inoue ◽

Ken Kobayashi ◽

Mizuki Sawada ◽

Sumiko Ishizaki ◽

Haruo Ito ◽

...

Keyword(s):

Malignant Melanoma ◽

Skin Lesions ◽

Japanese Woman ◽

Bowen’S Disease ◽

Seborrheic Keratosis ◽

Bowen's Disease ◽

Pathologic Features ◽

Old Japanese ◽

History Of ◽

Pigmented Skin Lesions

Various structures have been reported for dermoscopic features of pigmented Bowen's disease (BD), which could be a mimic of various pigmented skin lesions. A 79-year-old Japanese woman presented with a 3-year history of brown-black macule on her right upper arm without symptom. Dermoscopic examination demonstrated irregular flossy streaks, irregular brown dots/globules, blue-whitish regression structures, and overlaying whitish scaly areas. We suspected pigmented skin lesions including seborrheic keratosis, pigmented eccrine poroma, and malignant melanoma and excised completely with a 5 mm margin. Histopathological features were consistent with a diagnosis of pigmented BD. Although similar dermoscopic features might be revealed in pigmented skin lesions and it may occasionally be difficult to distinguish between pigmented BD and other pigmented skin lesions, dermoscopy would be useful in speculating pathologic features of pigmented BD.

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A case of Sphingomonas paucimobilis causing peritoneal dialysis-associated peritonitis and review of the literature

Renal Replacement Therapy ◽

10.1186/s41100-021-00375-3 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Chiharu Kinoshita ◽

Koichi Matsuda ◽

Yumiko Kawai ◽

Takayuki Hagiwara ◽

Akane Okada

Keyword(s):

Peritoneal Dialysis ◽

Japanese Woman ◽

Catheter Removal ◽

Sphingomonas Paucimobilis ◽

Test Results ◽

Review Of The Literature ◽

Case Presentation ◽

Old Japanese ◽

Empirical Antibiotics ◽

Number Of Cells

Abstract Background Peritoneal dialysis (PD)-associated peritonitis caused by Sphingomonas paucimobilis (S. paucimobilis) is very rare, and most of the characteristics of such cases are still unknown. Case presentation An 80-year-old Japanese woman on PD was diagnosed with PD-associated peritonitis and received ceftazidime and cefazolin. The number of cells in the peritoneal dialysate decreased quickly. However, because S. paucimobilis was detected, the antibiotic was changed to meropenem according to the susceptibility test results. She was treated with meropenem for two weeks and discharged. After 21 days, she was hospitalized for relapsing peritonitis. S. paucimobilis was detected again, and improvement after the administration of meropenem was poor, eventually resulting in catheter removal. Conclusions S. paucimobilis may be resistant to empirical antibiotics; furthermore, catheter removal may still be required, even with sensitive-antibiotic treatment.

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Mesectodermal Leiomyoma of the Ciliary Body: A Unique Variant of Leiomyoma with Myogenic and Neurogenic Histological Features

International Journal of Surgical Pathology ◽

10.1177/10668969211038694 ◽

2021 ◽

pp. 106689692110386

Author(s):

Osamu Inamori ◽

Hideki Fukuoka ◽

Michiko Nagamine ◽

Chie Sotozono ◽

Eiichi Konishi

Keyword(s):

Malignant Melanoma ◽

Ciliary Body ◽

Benign Tumor ◽

Frozen Section ◽

Smooth Muscle Actin ◽

Japanese Woman ◽

Reproductive Age ◽

Positive Staining ◽

Rare Benign Tumor ◽

Slow Growing

Mesectodermal leiomyoma of the ciliary body is a rare benign tumor, showing both neurogenic and myogenic characteristics. This tumor typically shows predilection for women of reproductive age. Because it is almost impossible to clinically distinguish this tumor from malignant melanoma, unnecessary eye enucleations have been unfortunately performed. Herein, we report a case of mesectodermal leiomyoma of the ciliary body in a young Japanese woman. She was referred to our hospital due to a slow-growing mass in her left iris. A malignant tumor could not be clinically ruled out and surgery with intraoperative pathology consultation was performed. Intraoperative frozen section diagnosis was a benign tumor with neurogenic features, and a simple excision of the tumor was performed. Histologically, the tumor was composed of diffuse growth of spindle cells with fibrillary indistinctive cytoplasm. Immunohistochemical examination showed diffuse positive staining of α-smooth muscle actin, h-caldesmon, calponin, and CD56. Scattered tumor cells were weakly positive for desmin. Neither melanocytic markers nor neural markers except for CD56 were positive. We diagnosed this tumor as mesectodermal leiomyoma. Mesectodermal leiomyoma is rare and often misdiagnosed as malignant melanoma. To avoid overtreatment, a correct preoperative diagnosis is essential.

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Renal Squamous Cell Carcinoma with Staghorn Calculus

Case Reports in Oncology ◽

10.1159/000506675 ◽

2020 ◽

Vol 13 (1) ◽

pp. 403-407

Author(s):

Ryo Kasahara ◽

Takashi Kawahara ◽

Ryosuke Tajiri ◽

Hiroji Uemura ◽

Kazuo Kitami

Keyword(s):

Computed Tomography ◽

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Percutaneous Nephrostomy ◽

Japanese Woman ◽

Pathologic Examination ◽

Xanthogranulomatous Inflammation ◽

Old Japanese ◽

Staghorn Calculus

A 70-year-old Japanese woman was referred to our department due to general fatigue and a persistent low fever. We performed percutaneous nephrostomy and administered antibiotics for the pyelonephritis due to her left staghorn calculus. After the infection had been brought under control and her general condition improved, we performed nephrectomy. A pathologic examination revealed renal squamous cell carcinoma (SCC) in addition to xanthogranulomatous inflammation. Seventeen days after the operation, computed tomography demonstrated local recurrence of the tumor; therefore, she received palliative care. Two months after her operation, she died of renal SCC.

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Clinically amyopathic dermatomyositis during the COVID-19 pandemic

Oxford Medical Case Reports ◽

10.1093/omcr/omab061 ◽

2021 ◽

Vol 2021 (8) ◽

Author(s):

Masakazu Kitamura ◽

Hiroshi Sugimoto

Keyword(s):

Computed Tomography ◽

Ct Scan ◽

Oral Prednisolone ◽

Skin Lesions ◽

Japanese Woman ◽

Ground Glass ◽

Amyopathic Dermatomyositis ◽

Chest Computed Tomography ◽

Clinically Amyopathic Dermatomyositis ◽

Old Japanese

ABSTRACT An 84-year-old Japanese woman presented to our hospital with a month-long dry cough during the coronavirus disease 2019 (COVID-19) pandemic. She also had skin lesions on her fingers from 3 months prior. A chest computed tomography (CT) scan showed bilateral ground- glass opacities with a subpleural distribution, similar to the findings of COVID-19. The results of COVID-19 tests were negative. The titer of the anti-melanoma differentiation-associated gene 5 (MDA5) antibody was elevated. Consequently, we confirmed the diagnosis of clinically amyopathic dermatomyositis (CADM) and then administered oral prednisolone combined with tacrolimus. After the treatment, her symptoms, skin lesions and CT findings were gradually resolved.

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Idiopathic collapsing focal segmental glomerulosclerosis in an 81-year-old Japanese woman: a case report and review of the literature

CEN Case Reports ◽

10.1007/s13730-016-0224-3 ◽

2016 ◽

Vol 5 (2) ◽

pp. 197-202 ◽

Cited By ~ 2

Author(s):

Jun Yamazaki ◽

Eriko Kanehisa ◽

Wakaba Yamaguchi ◽

Jiro Kumagai ◽

Kiyotaka Nagahama ◽

...

Keyword(s):

Case Report ◽

Focal Segmental Glomerulosclerosis ◽

Japanese Woman ◽

Review Of The Literature ◽

Segmental Glomerulosclerosis ◽

Old Japanese

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Maxillary haemangioma successfully resected by endoscopic approach

The Journal of Laryngology & Otology ◽

10.1017/s0022215108003071 ◽

2008 ◽

Vol 123 (7) ◽

pp. 793-795 ◽

Cited By ~ 7

Author(s):

T Kanazawa ◽

R Inoue ◽

Y Ohta ◽

Y Watanabe ◽

Y Iino

Keyword(s):

Case Report ◽

Paranasal Sinuses ◽

Endoscopic Sinus Surgery ◽

Rare Case ◽

Japanese Woman ◽

Sinus Surgery ◽

Wide Resection ◽

Review Of The Literature ◽

Large Tumour ◽

Old Japanese

AbstractObjective:We report an extremely rare case of maxillary haemangioma.Method:Case report and review of the literature concerning haemangioma arising from the nasal cavity and paranasal sinuses.Results:Maxillary haemangioma is rare and sometimes requires wider resection than nasal haemangioma if a large tumour is found. We present a case of maxillary haemangioma in a 37-year-old Japanese woman, which was completely resected by pre-operative embolisation and endoscopic sinus surgery.Conclusion:Our findings suggest that if a large maxillary haemangioma is diagnosed pre-operatively, the treatment of choice is pre-operative embolisation followed by endoscopic sinus surgery, in order to avoid the surgical complications associated with wide resection.

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