The effect of dietary protein source and saponins on serum lipids and the excretion of bile acids and neutral sterols in rabbits

1. Four groups of six rabbits were given purified diets in which the dietary variables were protein source (isolated soya-bean protein or cow's-milk protein) with or without saponin supplementation (10 g/kg).2. Rabbits given soya-based diets showed significantly lower serum concentrations of triglyceride and cholesterol (P < 0·01). The latter changes were confined to the cholesterol fractions of β-lipoproteins.3. These changes in serum cholesterol were associated with a significantly increased excretion of acid and neutral sterols in animals given soya-bean protein.4. There was no evidence to suggest that the effect of dietary protein source on serum lipids and the excretion of total and individual sterols was influenced by saponin supplementation.5. These results do not support the hypothesis that the hypocholesterolaemia associated with plant proteins is due to the presence of saponins.

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Air-classified faba bean protein concentrate is efficiently utilized as a dietary protein source by post-smolt Atlantic salmon ( Salmo salar )

Aquaculture ◽

10.1016/j.aquaculture.2015.10.035 ◽

2016 ◽

Vol 452 ◽

pp. 169-177 ◽

Cited By ~ 6

Author(s):

C. De Santis ◽

D.R. Tocher ◽

K. Ruohonen ◽

A. El-Mowafi ◽

S.A.M. Martin ◽

...

Keyword(s):

Atlantic Salmon ◽

Salmo Salar ◽

Faba Bean ◽

Dietary Protein ◽

Protein Source ◽

Protein Concentrate ◽

Atlantic Salmon Salmo Salar ◽

Dietary Protein Source ◽

Bean Protein

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Effect of dietary protein source on feed intake, growth, pancreatic enzyme activities and jejunal morphology in newly-weaned piglets

British Journal Of Nutrition ◽

10.1079/bjn19940039 ◽

1994 ◽

Vol 72 (3) ◽

pp. 353-368 ◽

Cited By ~ 56

Author(s):

Caroline A. Makkink ◽

George Puia Negulescu ◽

Qin Guixin ◽

Martin W. A. Verstegen

Keyword(s):

Feed Intake ◽

Dietary Protein ◽

Pancreatic Enzyme ◽

Milk Powder ◽

Soya Bean ◽

Protein Source ◽

Weaned Piglets ◽

Tissue Samples ◽

Freeze Dried ◽

Dietary Protein Source

Seventy piglets with no access to creep feed were weaned at 28 d of age and fed on one of four diets based on either skimmed-milk powder (SMP), soya-bean-protein concentrate (SPC), soya-bean meal (SBM) or fish meal (FM). At 0, 3, 6 and 10 d after weaning, piglets were killed and the pancreas and digesta from stomach and small intestine were collected, freeze-dried and analysed for dry matter (DM), N, and trypsin (EC3.4.21.4) and chymotrypsin (EC3.4.21.1) activities. Small-intestinal tissue samples were taken to examine gut wall morphology. Results indicated that dietary protein source affected post-weaning feed intake, pancreatic weight, gastric pH and gastric protein breakdown, and pancreatic and jejunal trypsin and chymotrypsin activities. Post-weaning feed intake appeared to be an important factor in digestive development of newly-weaned piglets.

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Effects of soya-bean protein and casein on serum cholesterol levels in rats

British Journal Of Nutrition ◽

10.1079/bjn19800018 ◽

1980 ◽

Vol 44 (2) ◽

pp. 113-121 ◽

Cited By ~ 49

Author(s):

Y. Nagata ◽

K. Imaizumi ◽

M. Sugano

Keyword(s):

Serum Cholesterol ◽

Dietary Protein ◽

Protein Isolate ◽

Soya Bean ◽

Male Rats ◽

Cholesterol Levels ◽

Definite Pattern ◽

Neutral Sterols ◽

The Difference ◽

Bean Protein

1. The effect of the soya-bean protein isolate and casein, both given 200 g/kg diet for 3–4 weeks, on serum cholesterol was compared in male rats.2. Soya-bean protein exerted a hypocholesteraemic effect only in a cholesterol-free low-fat (10 g maize oil/kg) diet, when the lowering action appeared independent of the strain of the rat or the feeding pattern. The results obtained with diets containing cholesterol or higher levels of fats or both showed no definite pattern of response.3. Although the decrease in serum cholesterol appeared greater in α-lipoprotiens than in β-lipoproteins, the proportion of the former to total cholesterol remained almost unchanged. The concentration of serum apo A-I was significantly lower in rats given the vegetable protein.4. Rats given soya-bean protein excreted significantly more neutral sterols.5. The serum amino acid pattern did not reflect the difference in dietary protein. Addition of cholesterol to the diets modified the serum aminogarm, the decrease in threonine being most marked in both protein groups.6. This study shows that the hypocholesteraemic action of soya-bean protein is easily modified by the type of diet.

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The effect of dietary protein source on serum lipids: Secondary data analysis from a randomized clinical trial

Journal of Clinical Lipidology ◽

10.1016/j.jacl.2016.09.014 ◽

2017 ◽

Vol 11 (1) ◽

pp. 46-54 ◽

Cited By ~ 3

Author(s):

Anda R. Gonciulea ◽

Deborah E. Sellmeyer

Keyword(s):

Clinical Trial ◽

Data Analysis ◽

Randomized Clinical Trial ◽

Dietary Protein ◽

Serum Lipids ◽

Secondary Data ◽

Secondary Data Analysis ◽

Protein Source ◽

Dietary Protein Source

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Digestion in the pig between 7 and 35 d of age

British Journal Of Nutrition ◽

10.1079/bjn19810108 ◽

1981 ◽

Vol 45 (2) ◽

pp. 321-336 ◽

Cited By ~ 39

Author(s):

R. H. Wilson ◽

Jane Leibholz

Keyword(s):

Small Intestine ◽

Milk Protein ◽

Intestinal Tract ◽

Live Weight ◽

Mean Value ◽

Soya Bean ◽

Protein Source ◽

Liquid Form ◽

Gastro Intestinal Tract ◽

Bean Protein

1. In two separate experiments, forty-four pigs weaned at 4–5 d of age were given diets containing milk or soya-bean proteins until slaughtered at 14, 28 or 35 d of age.2. The retention times of digesta in the stomach and the entire gastro-intestinal tract did not differ between pigs given pelleted diets containing milk or soya-bean protein.3. Digesta retention times in the stomach were shorter (61 v. 146 min) in pigs given a milk-protein diet in a liquid form than in pigs given the same diet in a pelleted form. The retention times in the whole gastro-intestinal tract were 42.8 v. 29.6 h on the respective diets.4. The total retention time of digesta in the gastro-intestinal tract increased with age of pigs between 14–35 d of age when given pelleted diets but not when given a liquid diet.5. The daily amount of digesta flowing through the anterior small intestine was unaffected by the source of protein. Greater endogenous secretions into the anterior small intestine were observed when pigs were fed ad lib. than when fed at 2 g nitrogen (45 g dry matter (DM))/kg live weight0.75 per d.6. The apparent digestion of DM to the ileum of pigs given milk, isolated soya-bean protein (ISP) (Promine D) or soya-bean meal (SBM) protein at 28 d of age was 0.826, 0.825 and 0.644 respectively.7. The apparent digestion of DM to the ileum of pigs given ISP (Supro 610) significantly increased with age of pigs from 0.851 at 14 d of age to 0.883 at 35 d of age. No increase was observed for pigs given milk protein.8. Differences in the digestibility of DM between protein sources were greater to the ileum than over the entire gastro-intestinal tract. The greatest increase in DM digestion from the ileum to the faeces occurred in pigs given SBM (0.644–0.874).9. Neither the protein source nor age of pigs influenced gastric pH values, the mean value being 4.05. pH increased along the small intestine and was not affected by the protein source or age of pig.

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Faculty Opinions recommendation of Vegetarian compared with meat dietary protein source and phosphorus homeostasis in chronic kidney disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8486956.8950067 ◽

2011 ◽

Author(s):

Timothy Meyer

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Dietary Protein ◽

Protein Source ◽

Dietary Protein Source

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THE INVOLVEMENT OF DIETARY PROTEIN SOURCE AND CHILLING IN THE ETIOLOGY OF DIARRHEA IN NEWLY WEANED PIGS

Canadian Journal of Animal Science ◽

10.4141/cjas82-140 ◽

1982 ◽

Vol 62 (4) ◽

pp. 1199-1209 ◽

Cited By ~ 8

Author(s):

V. A. POUTEAUX ◽

G. I. CHRISTISON ◽

C. S. RHODES

Keyword(s):

Transit Time ◽

Dietary Protein ◽

The Other ◽

Protein Source ◽

Coliform Bacteria ◽

Protein Concentrate ◽

Feeding Trial ◽

Short Term ◽

Buttermilk Powder ◽

Dietary Protein Source

Two experiments were conducted to evaluate the involvement of dietary protein and short-term chilling on the incidence of diarrhea and on transit time of digesta in pigs weaned at 3–4 wk of age. The three protein sources used were buttermilk powder (BMP), soybean meal (SBM) or pea protein concentrate (PPC), which provided 85% of the dietary protein. In exp. 1, 72 pigs were exposed to a 16 °C decrease in ambient temperature for 8 h on day 4 of a 9-day feeding trial; 72 pigs were not chilled. The pigs on the PPC diet gained less (539 g) (P < 0.05) than pigs on BMP (1183 g) or SBM (952 g) although intakes were similar. Neither diet nor chilling affected fecal moisture content or the incidence of diarrhea. The PPC ration increased (P < 0.05) transit time (slowed rate of passage) on day 8. Chilling on day 4 decreased (P < 0.05) transit time (18.7 vs. 25.6 h) on that day. Neither protein source nor chilling caused differences in total or coliform bacteria isolated from fecal samples on blood agar or MacConkey's agar. In exp. 2, eight chilled and nine control pigs were euthanized and the quantity of three markers in six segments of the gastrointestinal tract was determined. The PPC diet passed more slowly than the other diets. In chilled pigs, the chromic oxide front was closer to the anus, indicating an increased rate of passage. It was concluded that the severity of the cold exposure was not suffficient to induce diarrhea and that there was no interaction between the effects of chilling and of dietary protein. There was, however, a tendency for chilling to increase the rate of passage of digesta which could have an additive effect on the severity of nutritional diarrhea. Key words: Pigs, weaning, diarrhea, protein, cold, transit time.

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