The impact of a dedicated antenatal clinic on the obstetric and neonatal outcomes in adolescent pregnant women

Abstract Objective: To investigate the outcomes of fetuses or neonates of pregnant women with premature ventricular contractions (PVCs). Study design: 6, 148 pregnant women were prospectively enrolled in the study. Of these women, 103 with a PVC burden >0.5% were divided into two groups based on the presence or absence of adverse fetal or neonatal events. The adverse outcomes were compared between the groups to assess the impact of PVCs on pregnancy. Results: A total of 17 adverse events (12 cases) occurred among 103 pregnant women with PVCs, which was significantly higher than that among women without PVCs (11.65% vs. 2.93%, p<0.01). The median PVC burden among pregnant women with PVCs was 2.84% (1.02% to 6.1%). Furthermore, compared with that of the women without adverse events, the median PVC burden of women with adverse fetal or neonatal outcomes was significantly higher (9.02% vs. 2.30%, p<0.01). Multivariate logistic regression analysis demonstrated that PVC burden was associated with adverse fetal or neonatal outcomes among pregnant women with PVCs (OR: 1.34, 95% CI (1.11-1.61), p<0.01). Conclusions: Frequent PVCs have adverse effects on pregnancy, and the PVC burden might be an important factor associated with adverse fetal and neonatal outcomes among pregnant women with PVCs. Our cohort study indicated that the higher the PVC burden is, the higher the likelihood of adverse events would be.

Download Full-text

The Impact of Response to Iron Therapy on Maternal and Neonatal Outcomes among Pregnant Women with Anemia

American Journal of Obstetrics & Gynecology MFM ◽

10.1016/j.ajogmf.2022.100569 ◽

2022 ◽

pp. 100569

Author(s):

Sarah E. Detlefs ◽

Michael D. Jochum ◽

Bahram Salmanian ◽

Jennifer R McKinney ◽

Kjersti M. Aagaard

Keyword(s):

Pregnant Women ◽

Neonatal Outcomes ◽

Iron Therapy ◽

Maternal And Neonatal Outcomes ◽

The Impact

Download Full-text

Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes

European Thyroid Journal ◽

10.1530/etj-21-0035 ◽

2022 ◽

Vol 11 (1) ◽

Author(s):

Maria Lopes-Pereira ◽

Anna Quialheiro ◽

Patrício Costa ◽

Susana Roque ◽

Nadine Correia Santos ◽

...

Keyword(s):

Pregnant Women ◽

Fetal Loss ◽

Family Health ◽

Neonatal Outcomes ◽

Vulnerable Groups ◽

Psychomotor Development ◽

Obstetric Outcomes ◽

Childbearing Age ◽

Iodine Supplementation ◽

The Impact

Objectives Over 1.9 billion people worldwide are living in areas estimated to be iodine insufficient. Strategies for iodine supplementation include campaigns targeting vulnerable groups, such as women in pre-conception, pregnancy and lactation. Portuguese women of childbearing age and pregnant women were shown to be mildly-to-moderately iodine deficient. As a response, in 2013, the National Health Authority (NHA) issued a recommendation that all women considering pregnancy, pregnant or breastfeeding, take a daily supplement of 150–200 μg iodine. This study explored how the iodine supplementation recommendation has been fulfilled among pregnant and lactating women in Portugal, and whether the reported iodine supplements intake impacted on adverse obstetric and neonatal outcomes. Design and methods Observational retrospective study on pregnant women who delivered or had a fetal loss in the Braga Hospital and had their pregnancies followed in Family Health Units. Results The use of iodine supplements increased from 25% before the recommendation to 81% after the recommendation. This was mostly due to an increase in the use of supplements containing iodine only. Iodine supplementation was protective for the number of adverse obstetric outcomes (odds ratio (OR) = 0.791, P = 0.018) and for neonatal morbidities (OR = 0.528, P = 0.024) after controlling for relevant confounding variables. Conclusion The recommendation seems to have succeeded in implementing iodine supplementation during pregnancy. National prospective studies are now needed to evaluate the impact of iodine supplementation on maternal thyroid homeostasis and offspring psychomotor development and on whether the time of the beginning of iodine supplementation (how early during preconception or pregnancy) is relevant to consider.

Download Full-text

Level of awareness, knowledge and perception on COVID-19 among pregnant women attending antenatal clinics in Central Hospital Benin City, Edo state

Annals of Clinical and Biomedical Research ◽

10.4081/acbr.2021.116 ◽

2021 ◽

Vol 2 (1) ◽

Author(s):

Sunday Eghosasere Omozuwa ◽

Noel Ebehiremen Uwaibi

Keyword(s):

Pregnant Women ◽

Antenatal Clinic ◽

Viral Disease ◽

World Health ◽

Central Hospital ◽

Cross Sectional Survey ◽

Public Health Response ◽

Cross Sectional ◽

Benin City ◽

The Impact

Coronavirus disease (COVID-19) is an infectious viral disease caused by severe acute respiratory syndrome coronavirus-2, which affects mainly the respiratory system and was first discovered during an outbreak in Wuhan community in China December 2019. The outbreak was declared a pandemic by World Health Organization (WHO) March, 11th 2020 and a worldwide public health response has been engaged to address the impact. A descriptive cross sectional survey was utilized. A self- administered questionnaire on awareness, knowledge and perception of COVID-19 infection was administered to a total 420 pregnant women attending antenatal clinic in central Hospital Benin City for Data collection. Four hundred and fourteen (98.6%) of the respondents were aware of COVID-19 and 274 (66.2%) indicated television as their source of information. One hundred (24.2%) indicated radio while 92 (22.2%) implicated friends. One hundred and ninety seven (46.9%) of the respondents had good knowledge of COVID-19 while 68 (16.2%) had poor knowledge. There was a high level of awareness of COVID-19 among the pregnant women attending Antenatal clinic in central hospital Benin City and majority of them got their information from the television.

Download Full-text

EFFECT OF MALARIA INFECTION ON HEPATIC AND RENAL FUNCTIONS IN PREGNANT WOMEN ATTENDING ANTENATAL CLINIC AT GENERAL HOSPITAL DUTSE, JIGAWA-NIGERIA

FUDMA Journal of Sciences ◽

10.33003/fjs-2021-0502-666 ◽

2021 ◽

Vol 5 (2) ◽

pp. 526-530

Author(s):

J. B. Balogun ◽

Shamsiyya Sani Muhammad ◽

Musa Mustapha Dogara

Keyword(s):

Alkaline Phosphatase ◽

Pregnant Women ◽

Malaria Infection ◽

Extracellular Fluid ◽

Antenatal Clinic ◽

Sodium Potassium ◽

Renal Functions ◽

Significant Difference ◽

Two Factors ◽

The Impact

The effect of malaria infection on hepatic and renal functions in pregnancywas investigated. Three malarious and non-malarious pregnant women of age ranges 15 to 40 years with a mean (SD) of 23.5 (6.6) years and a median (IQR) of 20.5 (18.3 to 27) years were enrolled. Liver enzymes (AST, ALT and ALP) and Kidney (UCE) functions were determined using Randox standard assay kits. The levels of alkaline phosphatase (ALP) and albumin were significant as malaria infected pregnant women had significantly lowered levels of ALP and albumin compared to controls (21.3 vs 26.1 IU/L, P = 0.03 and 4.8 vs 6.0 g/dl P = 0.02). There was no significant difference between malaria infected pregnant women and their non-malarious counterparts (P > 0.05) in their renal functions. There was no significant difference in mean concentrations of urea, creatinine, sodium, potassium and chloride regardless of the severity of malaria. Usually in pregnancy markers of liver function decrease due to expansion of extracellular fluid except alkaline phosphatase which is elevated due to its placental origin. Results of this study showed decreased level of ALP which could possibly be an indication that the parasite has not reached its hepatic stage. The severity of gestational malaria depends on the initial immunity of the pregnant woman. The impact of malaria on pregnancy and conversely, the impact of pregnancy on malaria, are two factors which must be put into consideration during gestational malaria

Download Full-text

A Comparison of Capillary and Venous Blood Haematocrits of Pregnant Women in Nigeria: The Impact on Diagnosis and Prevalence of Anaemia in Pregnancy

BioMed Research International ◽

10.1155/2014/467056 ◽

2014 ◽

Vol 2014 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

Cyril Chukwudi Dim ◽

Emmanuel Onyebuchi Ugwu ◽

Ugochukwu Bond Anyaehie ◽

Kingsley Chukwu Obioha

Keyword(s):

Pregnant Women ◽

Venous Blood ◽

Antenatal Clinic ◽

Capillary Blood ◽

Strong Positive Correlation ◽

Blood Samples ◽

Nigeria Teaching Hospital ◽

Anaemia In Pregnancy ◽

The Impact ◽

In Pregnancy

Background. Volume of red cells in capillary blood varies from that of venous blood. The magnitude of this variation as well as its impact on the diagnosis of anaemia in pregnancy needs to be studied. This study demonstrates the disparity between capillary and venous PCV in pregnancy.Objectives. To determine whether capillary blood PCV (cPCV) differed from venous blood PCV (vPCV) of normal pregnant women in Enugu, Nigeria, and its effect on diagnosis and prevalence of anaemia.Methods. PCV was estimated using pairs of venous and capillary blood samples from 200 consecutive pregnant women at the Antenatal Clinic of University of Nigeria Teaching Hospital, Enugu, Nigeria.Results. Participants’ cPCV(median=34.0%,IQR=31.0–35.8)was significantly lower than their vPCV(median=34.0%,IQR=32.0–37.0)(Z=-6.85,P<0.001). However, women’s cPCV had strong positive correlation with their vPCV (r=0.883,P<0.001). The prevalence of anaemia among participants using capillary and venous blood was 33.5% (67/200) and 28.0% (56/200), respectively (O.R=1.3(CI 95%: 0.85, 1.98), P=0.233).Conclusions. Capillary blood PCV was lower than vPCV among pregnant women in Enugu, Nigeria. Nevertheless, the prevalence of anaemia derived from cPCV did not differ significantly from that of vPCV.

Download Full-text

Intramuscular meperidine analgesia at the beginning of active phase shortens labor duration without adverse effects on obstetric lacerations

Journal of Experimental and Clinical Medicine ◽

10.52142/omujecm.38.4.35 ◽

2021 ◽

Vol 38 (4) ◽

pp. 594-598

Author(s):

Mehmet GÜÇLÜ ◽

Nazan YURTÇU ◽

Samettin ÇELİK ◽

Canan Soyer ÇALIŞKAN ◽

Şafak HATIRNAZ ◽

...

Keyword(s):

Pregnant Women ◽

Active Phase ◽

Adverse Outcomes ◽

Neonatal Outcomes ◽

Second Stage Of Labor ◽

Second Stage ◽

Obstetric Lacerations ◽

Increased Risk ◽

The Impact ◽

First Stage Of Labor

The primary objectives of this study were to evaluate the impact of intramuscular meperidine on shortening of the active phase of labor, the neonatal outcome and the rate and severity of perineal lacerations in term pregnant women in the first stage of labor. A total of 571 primiparous term pregnant women delivered vaginally were included into this retrospective study. In 437 of them, meperidine (100 mg IM) at the beginning of the active phase was administered and 134 women did not receive any meperidine dose. The length of labor phases, obstetric lacerations, and neonatal outcomes were recorded. The results of this study showed that meperidine could be used safely as an obstetric analgesic with its additional benefit of shortening the active phase of the first stage and second stage of labor without increased risk of obstetric lacerations and perinatal adverse outcomes. In case of limited use of neuraxial analgesia in a busy state maternity hospital, intramuscular meperidine administration as obstetric analgesia seems beneficial in reducing the length of the active phase of the first stage of labor and the second stage of labor without adversely affecting obstetric lacerations and neonatal outcomes.

Download Full-text

A185 THE IMPACT OF PRIOR SURGERY ON ADVERSE PREGNANCY OUTCOMES IN PREGNANT PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Journal of the Canadian Association of Gastroenterology ◽

10.1093/jcag/gwab002.183 ◽

2021 ◽

Vol 4 (Supplement_1) ◽

pp. 200-201

Author(s):

R Chis ◽

P Tandon ◽

V W Huang

Keyword(s):

Inflammatory Bowel Disease ◽

Pregnant Women ◽

Bowel Disease ◽

Mode Of Delivery ◽

Neonatal Outcomes ◽

Total Proctocolectomy ◽

Increased Risk ◽

Significant Difference ◽

Inflammatory Bowel ◽

The Impact

Abstract Background During the course of inflammatory bowel disease (IBD), approximately 20% of patients with ulcerative colitis (UC) and 80% of Crohn’s disease (CD) patients will require surgery. The most common operation is total proctocolectomy and ileoanal pouch anastomosis (IPAA) for UC patients and ileocecal (IC) resection for CD. In pregnant IBD patients, guidelines name the presence of IPAA as a relative indication for Cesarean section (C-section). The effect of prior IBD-related surgery on mode of delivery and pregnancy-related outcomes remains unknown. Aims To describe pregnancy-related outcomes in pregnant women with IBD who have undergone prior IBD-related surgery. Methods We performed a retrospective cohort study of pregnant women with IBD including those with prior IBD-related surgeries including IPAA, IC resection, total or partial colectomy and ileostomy formation who delivered an infant at our medical center from 2016 to 2020. We assessed the mode of delivery, delivery characteristics (emergency vs. planned C-section) and maternal and neonatal outcomes Results Fifty-six UC patients and 64 CD patients were included in the analysis, of which 10 and 24 had undergone prior IBD-related surgery, respectively. The mean age at conception was 34.10 years in the surgical UC group and 30.30 years in the surgical CD group. Mode of delivery: C-section rates were higher in post-surgical compared to non-surgical UC patients (70% vs. 30.4%, p = 0.02). Similar numbers of C-sections were performed emergently in the surgical compared to non-surgical UC group (10% vs. 18%, p = 0.53). Comparatively, there was no significant difference in C-section rates in post -surgical compared to non-surgical CD mothers (50% vs. 40%, p = 0.44), with 13% performed emergently in both groups. Maternal outcomes: Gestational diabetes developed in 10% of surgical UC and 4.5% of surgical CD patients. Premature rupture of membranes developed in 10% of surgical UC and 9.1% of surgical CD patients. There was no difference in pre-eclampsia rates in the surgical and non-surgical CD groups (9.1% vs 13.2%, p = 0.64). Neonatal outcomes: There was no significant difference in pre-term birth rates in post-surgical compared to non-surgical UC mothers (10% vs. 15.2%, p = 0.67) or in surgical compared to non-surgical CD mothers (13.6% vs. 5.1%, p = 0.29). Neonatal Intensive Care Unit (NICU) requirements were higher in infants born to post-surgical CD compared to non-surgical CD mothers (18.2% vs. 2.7%, p = 0.04). More low birth weight (LBW) infants were born to post-surgical CD vs non-surgical CD mothers (13.6% vs. 0%, p = 0.02). Conclusions Women with IBD who have had prior IBD-related surgery may be at increased risk of developing adverse gestational and neonatal outcomes. Women with surgical UC have an increased incidence of Cesarean delivery. Funding Agencies None

Download Full-text

Educational program about Rubella among pregnant women attending antenatal clinic in Women’s Health Hospital, Assiut University, Egypt

Journal of Nursing Education and Practice ◽

10.5430/jnep.v8n11p111 ◽

2018 ◽

Vol 8 (11) ◽

pp. 111

Author(s):

Walaa H. Ibrahim ◽

Fatma R. Khalaf ◽

Ekram M. Abdel Khalek

Keyword(s):

Pregnant Women ◽

Women’S Health ◽

Women's Health ◽

Educational Program ◽

Personal Data ◽

First Trimester ◽

Antenatal Clinic ◽

Multiple Birth ◽

The Impact ◽

Health Hospital

Background and objective: Rubella or German measles is infectious disease that affects both child and adult, but when associated with pregnancy, especially in first trimester, fetus can be exposed to various problems as abortion, multiple birth defects, and congenital rubella syndrome (CRS). This study aimed to assess awareness of pregnant women about rubella and to identify the impact of an educational program about rubella for pregnant women attending antenatal outpatient clinic in Women’s Health Hospital, Assiut University, Egypt.Methods: Quasi-experimental research design was carried out included 300 pregnant women in their first trimester. Direct interview using a semi-structured questionnaire which involved two parts: part (1) included personal data, family, and medical history, and part (2) involved questions directed to pregnant women to assess their knowledge about rubella. An educational program was applied on women as an intervention by session meeting classes. The data of knowledge were collected after the intervention then analyzed.Results: More than one third (38%) of the studied pregnant women were 25-30 years. The mean score of knowledge regarding rubella among pregnant women was 5.83 ± 2.48 in the pretest which improved significantly in the posttest to 20.07 ± 1.86.Conclusions and recommendations: The results revealed lack of awareness regarding rubella among studied women which increased after the application of the educational program. It is important to increase the availability of antenatal care services and provide adequate counseling for women before pregnancy about Rubella infection.

Download Full-text