The role of enhanced plantar-surface sensory feedback on lower limb EMG during planned gait termination

2021 ◽  
pp. 1-11
Author(s):  
Kelly A. Robb ◽  
Jordan D. Hyde ◽  
Stephen D. Perry
Keyword(s):  
Lower Limb ◽  
Sensory Feedback ◽  
Gait Termination ◽  
Plantar Surface

The role of delayed lower limb embolectomy in patients with late ischemia

Chirurgia ◽  
2020 ◽  
Vol 32 (6) ◽  
Author(s):  
Walid M. Gamal ◽  
Abdrheem F. Mohamed ◽  
Zeniab M. Askary
Keyword(s):  
Lower Limb

scholarly journals The Role of Circulating Biomarkers in Peripheral Arterial Disease

2021 ◽  
Vol 22 (7) ◽  
pp. 3601
Author(s):  
Goren Saenz-Pipaon ◽  
Esther Martinez-Aguilar ◽  
Josune Orbe ◽  
Arantxa González Miqueo ◽  
Leopoldo Fernandez-Alonso ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Lower Limb ◽  
Prediction Models ◽  
Arterial Disease ◽  
Cardiac Damage ◽  
Thrombotic Occlusion ◽  
Medical Treatments ◽  
Peripheral Arterial ◽  
Inflammatory Molecules

Peripheral arterial disease (PAD) of the lower extremities is a chronic illness predominantly of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is one of the most prevalent CV conditions worldwide in subjects >65 years, estimated to increase greatly with the aging of the population, becoming a severe socioeconomic problem in the future. The narrowing and thrombotic occlusion of the lower limb arteries impairs the walking function as the disease progresses, increasing the risk of CV events (myocardial infarction and stroke), amputation and death. Despite its poor prognosis, PAD patients are scarcely identified until the disease is advanced, highlighting the need for reliable biomarkers for PAD patient stratification, that might also contribute to define more personalized medical treatments. In this review, we will discuss the usefulness of inflammatory molecules, matrix metalloproteinases (MMPs), and cardiac damage markers, as well as novel components of the liquid biopsy, extracellular vesicles (EVs), and non-coding RNAs for lower limb PAD identification, stratification, and outcome assessment. We will also explore the potential of machine learning methods to build prediction models to refine PAD assessment. In this line, the usefulness of multimarker approaches to evaluate this complex multifactorial disease will be also discussed.

Bilateral asymmetries in professional cyclists during a Grand Tour

2020 ◽  
pp. 1-7
Author(s):  
Alejandro Javaloyes ◽  
Manuel Mateo-March ◽  
Felipe P. Carpes ◽  
Manuel Moya-Ramon ◽  
Raúl Lopez-Grueso ◽  
...  
Keyword(s):  
Injury Prevention ◽  
Intensity Distribution ◽  
Power Output ◽  
Lower Limb ◽  
Overuse Injury ◽  
Power Balance ◽  
Grand Tour ◽  
Race Time ◽  
Potential Link

BACKGROUND: Pedalling asymmetries are a topic of interest to cycling coaches and athletes due to a potential link with performance and injury prevention. OBJECTIVES: The aim of this study is to describe the bilateral asymmetry of professional cyclists during two editions of a Grand Tour. METHODS: Here we set out to determine the power balance (power produced by each lower limb) between stronger and weaker leg (dominant vs. non-dominant) of 12 UCI professional cyclists competing at two Giro d’Italia editions. Power data were recorded during competition stages. Further analysis considered power data clustered into individual intensity zones (from Z1 to Z7). RESULTS: Higher intensity elicited better power balance (lower asymmetry) regardless of the stage profile. Intensity distribution analysed according to the role of the cyclist was lower for climbers in Z2 (p= 0.006) and Z7 (p= 0.002) and higher in Z5 (p= 0.023) compared to team helpers. Power balance ranged from 0 to 9 % across the different athletes. CONCLUSIONS: Increase in power output improves power balance, especially in team helpers, and the lower power balance at lower exercise intensities, which are most of the race time, may elicit significant cumulative loading on a given leg of the cyclists, which requires further attention regarding risks of overuse injury.

scholarly journals Role of adhesion molecules in the induction of restenosis after angioplasty in the lower limb

2006 ◽  
Vol 43 (5) ◽  
pp. 969-977 ◽  
Author(s):  
Peter Heider ◽  
Moritz Georg Wildgruber ◽  
Wolfgang Weiss ◽  
Hermann Jakob Berger ◽  
Eckstein Hans Henning ◽  
...  
Keyword(s):  
Adhesion Molecules ◽  
Lower Limb

Deep dissecting haematoma in patients with dermatoporosis: implications for home nursing

2021 ◽  
Vol 26 (Sup3) ◽  
pp. S6-S13
Author(s):  
Valentina Vanzi ◽  
Elena Toma
Keyword(s):  
Wound Healing ◽  
Emergency Management ◽  
Lower Limb ◽  
Essential Role ◽  
Early Recognition ◽  
Wound Management ◽  
Home Nursing ◽  
High Prevalence ◽  
Clinical Emergency

Dermatoporosis is a chronic cutaneous insufficiency/fragility syndrome with a high prevalence in older adults. Dermatoporotic skin becomes thin and fragile and tends to tear. It may lead to deep dissecting haematomas (DDHs) as a final stage of dermatoporosis, which is a clinical emergency. Management can be challenging, as patients with lower-limb haematomas are frequently older and affected by multiple comorbidities, or are probably on medications that negatively influence wound healing. This article describes the essential role of nurses in prevention, early recognition and wound management of DDHs in patients with dermatoporosis.

Pain relief with elastic therapeutic taping

2021 ◽  
pp. bmjspcare-2021-003381
Author(s):  
Ekta Gupta ◽  
Courtland Lee ◽  
Amy Ng ◽  
Eduardo Bruera
Keyword(s):  
Rating Scale ◽  
Symptom Burden ◽  
Substantial Improvement ◽  
Functional Mobility ◽  
Background Information ◽  
Symptom Improvement ◽  
Plantar Surface ◽  
Pain Rating Scale ◽  
Pain Improvement

Background and purposeChemotherapy-induced peripheral neuropathy (CIPN) occurs in 19%–85% of patients undergoing cancer treatment. Due to the high symptom burden, specifically pain in the soles of feet, we explore the role of elastic therapeutic (ET) taping for treatment of CIPN.Case descriptionWe report two cases of patients with CIPN-induced foot pain while admitted to the hospital. Their background information, including chemotherapy history, treatments trialed and effects of ET on their pain, is discussed. Each patient underwent ET using the epidermis, dermis, fascia technique for CIPN. An occupational therapist applied ET to the plantar surface of both feet to the ankle with 0% stretch on the tape for 24–96 hours. We also showed the effect of symptom improvement in their individualized rehabilitation session following application of ET.OutcomesPain score, verbally documented by 10 point numerical pain rating scale, decreased by >50% in both patients within 24 hours of application. This reflects a substantial improvement in pain with the intervention of ET. This allowed for improved tolerance in engaging in functional mobility, with improvement in distances ambulated.DiscussionET taping of the distal leg and foot showed pain improvement for these two patients. Our findings suggest that a clinical trial aimed at better characterising the role of ET in these patients is justified.

scholarly journals Shared mechanisms of auditory and non-auditory vocal learning in the songbird brain

2021 ◽  
Author(s):  
James McGregor ◽  
Abigail Grassler ◽  
Paul I. Jaffe ◽  
Amanda Louise Jacob ◽  
Michael Brainard ◽  
...  
Keyword(s):  
Reinforcement Learning ◽  
Basal Ganglia ◽  
General Principle ◽  
Auditory Feedback ◽  
Sensory Feedback ◽  
Vocal Learning ◽  
Neural Systems ◽  
Auditory Information ◽  
Vocal Plasticity

Songbirds and humans share the ability to adaptively modify their vocalizations based on sensory feedback. Prior studies have focused primarily on the role that auditory feedback plays in shaping vocal output throughout life. In contrast, it is unclear whether and how non-auditory information drives vocal plasticity. Here, we first used a reinforcement learning paradigm to establish that non-auditory feedback can drive vocal learning in adult songbirds. We then assessed the role of a songbird basal ganglia-thalamocortical pathway critical to auditory vocal learning in this novel form of vocal plasticity. We found that both this circuit and its dopaminergic inputs are necessary for non-auditory vocal learning, demonstrating that this pathway is not specialized exclusively for auditory-driven vocal learning. The ability of this circuit to use both auditory and non-auditory information to guide vocal learning may reflect a general principle for the neural systems that support vocal plasticity across species.

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