AbstractThis meta-analysis was conducted to predict and assert a way to discover conjugated linoleic acid (CLA) formation in ruminant-derived products as problem solver of human health issues threated by plant-containing tannins. The objective was to expound, to compare, and to confirm the efficiency of tannins cultivating CLA formation whether using in vitro and/or in vivo study. A database was created using the ruminants with selectively 26 experiments comprising 683 dietary treatments as explained in vitro and in vivo methods that were applied as a statistical SAS 9.4 tool. Basically, increasing level of tannins leaded to an underlying decrease in CLA formation (p<0.001), initially at predicting coefficient determination R2=0.193, R2=0.929, and R2=0.549 for CLA in vitro, in vivo of CLA milk shift, and in vivo of CLA meat precipitation, respectively. In vitro may accurately predict to the in vivo observation. Unfortunately, there were no relationship in vitro towards in vivo observation (R2<0.1). It indicated to be difficult to predict CLA from in vitro to in vivo separately situations. According to all studies, the level of tannin’s utilization for inhibiting biohydrogenation was not exceedingly >50 g/kg DM recommended. Secondly, the in vivo method was more suitable for directly observation that concerned in fatty acid transformation.
Conjugated linoleic acid: A potent fatty acid linked to animal and human health
