Keys to embracing aging: A healthy aging intervention

2021 ◽  
pp. 1-14
Author(s):  
Amy F. Kostelic ◽  
Erin Yelland ◽  
Allison Smith ◽  
Cynthia Shuman ◽  
Adam Cless
Keyword(s):  
Healthy Aging ◽  
Aging Intervention

scholarly journals Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Yuqing Dong ◽  
Sujay Guha ◽  
Xiaoping Sun ◽  
Min Cao ◽  
Xiaoxia Wang ◽  
...  
Keyword(s):  
Healthy Aging ◽  
Intervention Studies ◽  
Biological Process ◽  
Biological Activities ◽  
Model Organisms ◽  
Dietary Interventions ◽  
Aging Intervention ◽  
Effective Interventions ◽  
Invertebrate Models ◽  
Shed Light

Aging is a complex and inevitable biological process that is associated with numerous chronically debilitating health effects. Development of effective interventions for promoting healthy aging is an active but challenging area of research. Mechanistic studies in various model organisms, noticeably two invertebrates,Caenorhabditis elegansandDrosophila melanogaster, have identified many genes and pathways as well as dietary interventions that modulate lifespan and healthspan. These studies have shed light on some of the mechanisms involved in aging processes and provide valuable guidance for developing efficacious aging interventions. Nutraceuticals made from various plants contain a significant amount of phytochemicals with diverse biological activities. Phytochemicals can modulate many signaling pathways that exert numerous health benefits, such as reducing cancer incidence and inflammation, and promoting healthy aging. In this paper, we outline the current progress in aging intervention studies using nutraceuticals from an evolutionary perspective in invertebrate models.

scholarly journals DEVELOPMENT OF TECHNOLOGIES FOR HEALTHY AGING: SEARCHING FOR THE RIGHT WAY

2016 ◽  
pp. 1-4
Author(s):  
A. Piau ◽  
E. Campo ◽  
B. Vellas ◽  
F. Nourhashemi
Keyword(s):  
Healthy Aging ◽  
Older Person ◽  
Field Methods ◽  
Health Technologies ◽  
Aging Intervention ◽  
Multidimensional Evaluation ◽  
Commercial Market ◽  
Number Of Publications ◽  
The Right ◽  
Development Methods

Background: Medical imaging (e.g. PET-scan) and interventional (e.g. robotic surgery) technologies seem- to better fit the actual technological progress than do technologies for aging. The commercial market of aging care remains subdued since the introduction of low-technology devices decades ago (e.g. walker). Revisiting the evaluation and development methods of technologies to support healthy aging could help spread innovative technologies in this field. Methods and findings: In literature, a number of publications have been identified that addresses issues about technological devices that target the different needs of the older person. Nevertheless, a successful evaluation and development often remains unmet. This deficiency arises to a large extent from the confrontation of two worlds: that of technology which is not yet well versed in the field of healthy aging intervention, and the medical world which mainly uses the linear pharmaceutical drug development model. Many methods propose to tackle the global multidimensional evaluation of health technologies. However, they do not address the sequencing of the whole development and evaluation processes. In the present paper, we present a framework to help tackle the complexity of healthy aging technologies assessment and development. Conclusion: The evaluation and development methods usually adopted for healthy aging technologies are not appropriate and that all the collaborative multidisciplinary processes have to be revised.

scholarly journals The Memory Fitness Program: Cognitive Effects of a Healthy Aging Intervention

2012 ◽  
Vol 20 (6) ◽  
pp. 514-523 ◽  
Author(s):  
Karen J. Miller ◽  
Prabha Siddarth ◽  
Jean M. Gaines ◽  
John M. Parrish ◽  
Linda M. Ercoli ◽  
...  
Keyword(s):  
Healthy Aging ◽  
Cognitive Effects ◽  
Fitness Program ◽  
Aging Intervention

scholarly journals Hormesis as a Pro-Healthy Aging Intervention in Human Beings?

Dose-Response ◽  
2009 ◽  
Vol 8 (1) ◽  
pp. dose-response.0 ◽  
Author(s):  
Francine Z. Marques ◽  
M. Andrea Markus ◽  
Brian J. Morris
Keyword(s):  
Healthy Aging ◽  
Human Beings ◽  
Aging Intervention

Longitudinal Changes in Individual BrainAGE in Healthy Aging, Mild Cognitive Impairment, and Alzheimer’s Disease

GeroPsych ◽  
2012 ◽  
Vol 25 (4) ◽  
pp. 235-245 ◽  
Author(s):  
Katja Franke ◽  
Christian Gaser
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Healthy Aging ◽  
Brain Aging ◽  
Elderly Subjects ◽  
Additional Increase ◽  
Longitudinal Changes ◽  
Novel Method ◽  
The Brain

We recently proposed a novel method that aggregates the multidimensional aging pattern across the brain to a single value. This method proved to provide stable and reliable estimates of brain aging – even across different scanners. While investigating longitudinal changes in BrainAGE in about 400 elderly subjects, we discovered that patients with Alzheimer’s disease and subjects who had converted to AD within 3 years showed accelerated brain atrophy by +6 years at baseline. An additional increase in BrainAGE accumulated to a score of about +9 years during follow-up. Accelerated brain aging was related to prospective cognitive decline and disease severity. In conclusion, the BrainAGE framework indicates discrepancies in brain aging and could thus serve as an indicator for cognitive functioning in the future.

Psychophysiological Responses to Stress Related to Anxiety in Healthy Aging

2019 ◽  
Vol 33 (3) ◽  
pp. 188-197 ◽  
Author(s):  
Roberta Adorni ◽  
Agostino Brugnera ◽  
Alessia Gatti ◽  
Giorgio A. Tasca ◽  
Kaoru Sakatani ◽  
...  
Keyword(s):  
Healthy Aging ◽  
Near Infrared ◽  
Response Times ◽  
Cognitive Resources ◽  
Stressful Condition ◽  
Healthy Elderly ◽  
Situational Stress ◽  
Anxiety Response ◽  
Nirs Signal ◽  
Psychophysiological Correlates

Abstract. The aim of the study was to explore the effects of situational stress and anxiety in a group of healthy elderly, both in terms of psychophysiological correlates and cognitive performance. Eighteen participants ( Mage = 70 ± 6.3; range 60–85) were assessed for anxiety and were instructed to perform a computerized math task, under both a stressful and a control condition, while near-infrared spectroscopy (NIRS) signal and electrocardiography (ECG) were recorded. NIRS results evidenced an increased activation of right PFC during the entire procedure, even if effect sizes between left and right channels were larger during the experimental condition. The amount of right activation during the stressful condition was positively correlated with anxiety. Response times (RTs) were slower in more anxious than in less anxious individuals, both during the control and stressful conditions. Accuracy was lower in more anxious than in less anxious individuals, only during the stressful condition. Moreover, heart rate (HR) was not modulated by situational stress, nor by anxiety. Overall, the present study suggests that in healthy elderly, anxiety level has a significant impact on cerebral responses, and both on the amount of cognitive resources and the quality of performance in stressful situations.

Prospective Memory Development Across the Lifespan

2020 ◽  
Vol 25 (3) ◽  
pp. 162-173 ◽  
Author(s):  
Sascha Zuber ◽  
Matthias Kliegel
Keyword(s):  
Prospective Memory ◽  
Healthy Aging ◽  
Present Model ◽  
Current Knowledge ◽  
Well Being ◽  
The Elderly ◽  
Cognitive Factors ◽  
Everyday Functioning ◽  
Integrative Framework

Abstract. Prospective Memory (PM; i.e., the ability to remember to perform planned tasks) represents a key proxy of healthy aging, as it relates to older adults’ everyday functioning, autonomy, and personal well-being. The current review illustrates how PM performance develops across the lifespan and how multiple cognitive and non-cognitive factors influence this trajectory. Further, a new, integrative framework is presented, detailing how those processes interplay in retrieving and executing delayed intentions. Specifically, while most previous models have focused on memory processes, the present model focuses on the role of executive functioning in PM and its development across the lifespan. Finally, a practical outlook is presented, suggesting how the current knowledge can be applied in geriatrics and geropsychology to promote healthy aging by maintaining prospective abilities in the elderly.

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