scholarly journals Computational screening of chalcones acting against topoisomerase IIα and their cytotoxicity towards cancer cell lines

2018 ◽  
Vol 34 (1) ◽  
pp. 134-143 ◽  
Author(s):  
Kanyani Sangpheak ◽  
Monika Mueller ◽  
Nitchakan Darai ◽  
Peter Wolschann ◽  
Chonticha Suwattanasophon ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Topoisomerase Iiα ◽  
Computational Screening

scholarly journals Enhanced Topoisomerase I Activity and Increased Topoisomerase IIα Content in Cisplatin-resistant Cancer Cell Lines

1997 ◽  
Vol 88 (12) ◽  
pp. 1218-1223 ◽  
Author(s):  
Yukihisa Minagawa ◽  
Junzo Kigawa ◽  
Takashi Irie ◽  
Yasunobu Kanamori ◽  
Hiroaki Itamochi ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Topoisomerase I ◽  
Cancer Cell Lines ◽  
Topoisomerase Iiα

scholarly journals Design and synthesis of DNA-intercalative naphthalimide-benzothiazole/cinnamide derivatives: cytotoxicity evaluation and topoisomerase-IIα inhibition

MedChemComm ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 72-79 ◽  
Author(s):  
N. Sankara Rao ◽  
Narayana Nagesh ◽  
V. Lakshma Nayak ◽  
Satish Sunkari ◽  
Ramya Tokala ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Topoisomerase Iiα ◽  
Human Cancer Cell Lines ◽  
Design And Synthesis

A new series of different naphthalimide-benzothiazole/cinnamide derivatives were designed, synthesized and tested for their in vitro cytotoxicity on selected human cancer cell lines.

scholarly journals Synthesis and photobiological applications of naphthalimide–benzothiazole conjugates: cytotoxicity and topoisomerase IIα inhibition

RSC Advances ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 483-497
Author(s):  
Iqubal Singh ◽  
Vijay Luxami ◽  
Diptiman Choudhury ◽  
Kamaldeep Paul
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Cervix Cancer ◽  
Topoisomerase Iiα ◽  
A549 Lung

Conjugates of naphthalimide, benzothiazole, and indole moieties are synthesized that show excellent cytotoxicity against A549 (lung), MCF7 (breast), and HeLa (cervix) cancer cell lines with IC50 values in the range of 0.14–8.59 μM.

797: Noggin Blocks the Osteoinductive Properties of Human Prostate Cancer Cell Lines

2006 ◽  
Vol 175 (4S) ◽  
pp. 258-258
Author(s):  
Ruth Schwaninger ◽  
Cyrill A. Rentsch ◽  
Antoinette Wetterwald ◽  
Irena Klima ◽  
Gabri Van der Pluijm ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Lines ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Human Prostate Cancer Cell ◽  
Prostate Cancer Cell Lines
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