Effects of high-concentration salt solutions and pH on swelling behavior of physically and chemically cross-linked hybrid hydrophobic association hydrogels with good mechanical strength

2018 ◽  
Vol 16 (4) ◽  
pp. 249-264 ◽  
Author(s):  
Shuling Gao ◽  
Guoqing Jiang ◽  
Bo Li ◽  
Peihui Han
2010 ◽  
Vol 47 (7) ◽  
pp. 663-670 ◽  
Author(s):  
Guoqing Jiang ◽  
Chang Liu ◽  
Xiaoli Liu ◽  
Guohui Zhang ◽  
Meng Yang ◽  
...  

Polymers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 2535
Author(s):  
Ji-Bong Choi ◽  
Yu-Kyoung Kim ◽  
Seon-Mi Byeon ◽  
Jung-Eun Park ◽  
Tae-Sung Bae ◽  
...  

In this study, a hydrogel using single and double crosslinking was prepared using GelMA, a natural polymer, and the effect was evaluated when the double crosslinked hydrogel and tannic acid were treated. The resulting hydrogel was subjected to physicochemical property evaluation, biocompatibility evaluation, and animal testing. The free radicals generated through APS/TEMED have a scaffold form with a porous structure in the hydrogel, and have a more stable structure through photo crosslinking. The double crosslinked hydrogel had improved mechanical strength and better results in cell compatibility tests than the single crosslinked group. Moreover, in the hydrogel transplanted into the femur of a rat, the double crosslinked group showed an osteoinductive response due to the attachment of bone minerals after 4 and 8 weeks, but the single crosslinked group did not show an osteoinductive response due to rapid degradation. Treatment with a high concentration of tannic acid showed significantly improved mechanical strength through H-bonding. However, cell adhesion and proliferation were limited compared to the untreated group due to the limitation of water absorption capacity, and no osteoinduction reaction was observed. As a result, it was confirmed that the treatment of high-concentration tannic acid significantly improved mechanical strength, but it was not a suitable method for improving bone induction due to the limitation of water absorption.


RSC Advances ◽  
2015 ◽  
Vol 5 (108) ◽  
pp. 89083-89091 ◽  
Author(s):  
Huijuan Zhang ◽  
Xianjuan Pang ◽  
Yuan Qi

A pH-sensitive and mechanically strong graphene oxide/sodium alginate/polyacrylamide nanocomposite semi-IPN hydrogel was designed and prepared. The composite semi-IPN hydrogel showed superior mechanical strength and pH-dependent swelling behavior.


2015 ◽  
Vol 74 (1) ◽  
pp. 793-802 ◽  
Author(s):  
W. M. Ye ◽  
C. M. Zhu ◽  
Y. G. Chen ◽  
B. Chen ◽  
Y. J. Cui ◽  
...  

Micromachines ◽  
2020 ◽  
Vol 11 (4) ◽  
pp. 425
Author(s):  
Daniela Franke ◽  
Gerald Gerlach

In this article, we present a semi-interpenetrating network (IPN) hydrogel of reasonable size with improved swelling behavior. The semi-IPN is composed of N-isopropylacrylamide and 2-acrylamido-2-methyl-1-propanesulfonic acid. Porosity was generated chemically by a surfactant-based template method. The swelling behavior was measured after an abrupt change of the temperature to 25 °C or 40 °C or after an abrupt change of the salt concentration of the aqueous medium surrounding the hydrogel samples. A set of static swelling degrees was determined from swelling measurements in salt solutions of varying concentrations and at different temperatures. Introducing porosity to the semi-IPN decreases the swelling times for most measurements while the sensor and actuator characteristics of the hydrogel found in previous studies are preserved. Additionally, we propose theoretical assumptions and explanations regarding the differences in the swelling kinetics of the porous and the nonporous semi-IPN and deduce implications for sensor and actuator applications.


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