Antimicrobial Edible Films and Coatings based on N,O-Carboxymethyl Chitosan incorporated with Ferula Asafoetida (Hing) and Adhatoda Vasica (Adulsa) extract

Durian (Durio zibethinus) and cempedak (Artocarpus integer) peels waste are not used by the society. The research aim is to extract pectin from durian and cempedak peels and to formulate the pectin into edible films for food packaging. The research stages were first pre-treatment of durian and cempedak peels, pectin extraction, pectin drying, and pectin application as edible films with concentration of 0%, 5%, and 15%. Based on this research it was concluded that pectin can be extracted from durian and cempedak peels with yield result of 27.97 % and 55.58 %, respectively. Edible film obtained has similar characteristics between raw materials cempedak and durian peels. The higher concentration of cempedak peel pectin increased the thickness, but decreased the tensile strength and elongation at a concentration of 15%. While in edible films from durian peel pectin, the higher concentration of pectin decreased the thickness of edible film on pectin concentration of 15%, lowered tensile strength and raised the edible film elongation.Keywords: waste, durian, cempedak, pectin extraction, edible film

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Obtaining and Characterisation of Starch-Based Edible Films Incorporating Honey, Propolis and Bee Bread

Acta Universitatis Cibiniensis Series E Food Technology ◽

10.2478/aucft-2019-0023 ◽

2019 ◽

Vol 23 (2) ◽

pp. 193-198

Author(s):

Monica Mironescu ◽

Laura Fratila ◽

Alexandru Hupert ◽

Ion Dan Mironescu

Keyword(s):

Water Activity ◽

Mechanical Characteristics ◽

Edible Films ◽

Ash Content ◽

Colour Intensity ◽

Sensorial Analysis ◽

Physical Chemical ◽

Control Film ◽

Bee Bread

Abstract This research investigates the physical-chemical, sensorial and mechanical characteristics of starch-based edible films incorporating three types of bee hive products: honey, propolis and bee bread, in concentrations varying from 1% to 3%, reported to starch. The results indicates an increasing of films moisture, water activity, ash content and acidity, in the order: honey<propolis<bee bread, all values increasing with the increasing of hive products percentage into the control film; aw is remaining at very low values, under 0.4. Sensorial analysis indicated honey as the better suited for improving taste and flavour and bee bread for increasing colour intensity of the films; the sensorial characteristics are maintained during 30 days of films storage, in all cases. Compared with the control starch-based film (which is elastic, brittle and hard), the films containing 2% bee hive products are elasto-plastic and more resistant to penetration, the resistance increasing in the order: bee bread<propolis<honey.

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Antimicrobial Effect of Ferula Asafoetida against Escherichia Coli when Incorporated in Commercially Available Intracanal Medicament- Calcium Hydroxide: An In Vitro Study

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2020.sp1.420 ◽

2020 ◽

Vol 12 (sp1) ◽

Keyword(s):

Escherichia Coli ◽

Calcium Hydroxide ◽

In Vitro Study ◽

Antimicrobial Effect ◽

Vitro Study ◽

Ferula Asafoetida

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Effects of Carboxymethyl Chitosan on Yield and Whey Protein Loss in Cottage Cheese

Preventive Nutrition and Food Science ◽

10.3746/jfn.2005.10.3.231 ◽

2005 ◽

Vol 10 (3) ◽

pp. 231-238 ◽

Cited By ~ 4

Author(s):

Kyung-Tae Kim ◽

Ok-Ju Kang

Keyword(s):

Whey Protein ◽

Carboxymethyl Chitosan ◽

Cottage Cheese ◽

Protein Loss

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Carboxymethyl-hexanoyl Chitosan Nanodroplets for Ultrasonic Imaging and Drug Delivery to Tumor

Current Pharmaceutical Design ◽

10.2174/1381612824666180515122836 ◽

2018 ◽

Vol 24 (15) ◽

pp. 1682-1688 ◽

Cited By ~ 3

Author(s):

Yu Jinsui ◽

Situ Bing ◽

Luo Muhua ◽

Li Yue ◽

Liao Jianyi ◽

...

Keyword(s):

Ultrasound Imaging ◽

Tumor Therapy ◽

Carboxymethyl Chitosan ◽

Great Promise ◽

Ovarian Cancer Cells ◽

Mechanical Index ◽

Surface Charges ◽

Particle Structure ◽

Drug Release Profile ◽

Hexanoyl Chitosan

Introduction: Although a great many strategies have been proposed for tumor-targeted chemotherapy, current delivery methods of anticancer drugs present limited success with inevitable systemic toxicity. The aim of this study was to develop a new kind of theranostic carrier for targeted tumor therapy. Methods: Prior to prepare CHC-PFP-DOX, carboxymethyl-hexanoyl chitosan (CHC) was synthesized by acylation of carboxymethyl chitosan. To develop CHC-PFP, perfluoropentane (PFP), an ultrasound gas precursor, was simultaneously encapsulated into the hydrophobic inner cores of pre-formulated CHC micelle in aqueous phase via using the oil in water (O/W) emulsion method. The size distribution and surface charges of these nanodroplets were measured and the morphology was observed by transmission electron microscopy (TEM). For ultrasound imaging application, in vitro model was established to evaluate the imaging of CHC-PFP-DOX under different concentration and mechanical index. After that, the anti-tumor effect of ultrasound combined with CHC-PFPDOX on ovarian cancer cells was investigated. Results: The resulting CHC-PFP-DOX had a nano-sized particle structure, with hydrophobic anticancer DOX/PFP inner cores and a hydrophilic carboxymethyl chitosan polymer outer shell. The favorable nano-scaled size offers the potential to extravagate from veins and accumulate in tumor tissues via enhanced permeation and retention (EPR) effect. Additionally, CHC-PFP-DOX showed the ability to serve as ultrasound imaging agent at body temperature. Notably, it exhibited an ultrasound-triggered drug release profile through the external ultrasound irradiation. Further study demonstrated that ultrasound combined with CHC-PFP-DOX can improve the killing effect of chemotherapy for tumor. Conclusion: CHC-PFP-DOX holds great promise in simultaneous cancer-targeting ultrasound imaging and ultrasound- mediated delivery for cancer chemotherapy.

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