scholarly journals THE POSTMORTEM RIGOR OF THE MAMMALIAN HEART AND THE INFLUENCE OF AN ANTEMORTEM STIMULATION OF THE PNEUMOGASTRIC NERVES UPON ITS DEVELOPMENT

1909 ◽  
Vol 11 (2) ◽  
pp. 314-325 ◽  
Author(s):  
Don R. Joseph ◽  
S. J. Meltzer
Keyword(s):  
Right Ventricle ◽  
Skeletal Muscles ◽  
Inhibitory Influence ◽  
Vital Activity ◽  
Cardiac Tissues ◽  
The Difference ◽  
Probable Interpretation ◽  
The One ◽  
The Right ◽  
Spontaneous Contractions

In normal animals (dogs, cats and rabbits) which were killed by exsanguination, the beginning of rigor in practically all cases was separated from respiratory death by two well characterized periods: (1) a period of pulsation during which each ventricle still exhibited some spontaneous contractions, and (2) a period of relaxation during which the ventricles, while showing neither spontaneous contractions nor rigor, are more relaxed than in normal diastole, and during which the ventricles gradually lose their irritability. (The cardiac rigor or tonic contraction which was observed by recent investigators to set in immediately after death is an artificial phenomenon produced by filling the heart with saline and connecting it with a manometer.) In the right ventricle both periods are longer than in the left ventricle, i. e., rigor sets in later. Moreover the development of rigor from onset to maximum is also longer in the right ventricle than in the left, although here the difference is less striking. The stopping of spontaneous beating, the disappearance of irritability, and the development of rigor, manifest in both ventricles a topographical progress from the base toward the apex, i. e., the stoppage of beating, the disappearance of irritability and the setting in of rigor occur first at the uppermost part of the ventricle and last at the lowest point of the ventricle. It often occurred that rigor was already present in the basal part of a ventricle while the apex was still beating. It is probable also that the loss of vital activity and irritability and the development of rigor progress topographically from the endocardial to the epicardial surfaces. Prolonged etherization retards the onset, but hastens the development of rigor; atropinization hastens both onset and development. Repeated prolonged stoppages of the heart caused by antemortem (and postmortem) stimulations of the pneumogastric nerves hasten the onset as well as the development of rigor of the heart. All three periods are affected by the inhibitory influence of the stimulation, the period of relaxation, however, seems to be the one which is shortened most. The most probable interpretation of this phenomenon is the assumption that it is caused by an asphyxiation of the cardiac tissues. The stimulations of the pneumogastric nerves seem to hasten also the onset of the general rigor—probably this, too, is the result of some premature asphyxiation of the skeletal muscles.

scholarly journals Reciprocal innervation and symmetrical muscles

1913 ◽  
Vol 86 (587) ◽  
pp. 219-232 ◽  
Keyword(s):  
Skeletal Muscles ◽  
Knee Extensor ◽  
General Rule ◽  
The Body ◽  
Ordinary Sense ◽  
Excitatory Effect ◽  
Biological Meaning ◽  
Vasomotor Reflexes ◽  
The One ◽  
The Right

If we attempt to decipher the biological meaning of reciprocal innervation its various instances when marshalled together say plainly that one of the functional problems which it meets and solves is mechanical antagonism. Where two muscles have directly opposed effect on the same lever, “reciprocal innervation” is the general rule observed by the nervous system in dealing with them, and this holds whether the reciprocal innervation is peripheral as with the antagonists of the arthropod claw, or is central as with vertebrate skeletal muscles. Also where one and the same muscle is governed by two nerves influencing it oppositely, reciprocal innervation seems again the principle followed in the co-ordination of the two opponent centres, as has been shown by Bayliss in his observations on vasomotor reflexes. But the distribution and occurrence of reciprocal innervation extend beyond cases of mere mechanical antagonism. The reflex influence exerted by the limb-afferents on symmetrical muscle-pairs such as right knee-extensor and left is reciprocal. Thus right peroneal nerve excites the motoneurones of left vastocrureus, and concomitantly inhibits those of the right. The reflex inhibition of the one is concurrent with, increases with increase, and decreases with decrease of, the excitatory effect on the other. Here the muscles are not in any ordinary sense antagonistic; not only do they not operate on the same lever, but they are not even members of the same limb, nor do they belong even to the same half of the body. They are, however, actuated conversely in the most usual modes of progression—the walking and the running step—though not always in galloping.

Pushmi-Pullyu and the Right Atrium

2011 ◽  
pp. 55-62
Author(s):  
James R. Munis
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Right Ventricle ◽  
Flow Rate ◽  
Blood Flow Rate ◽  
The Other ◽  
Right Atrial ◽  
The One ◽  
The Right ◽  
Point Of Intersection

What does right atrial pressure (PRA) do to cardiac output (CO)? On the one hand, we've been taught that PRA represents preload for the right ventricle. That is, the higher the PRA, the greater the right ventricular output (and, therefore, CO). This is simply an application of Starling's law to the right side of the heart. On the other hand, we've been taught that PRA represents the downstream impedance to venous return (VR) from the periphery. That is, the higher the PRA, the lower the VR, and therefore, the lower the CO. The point of intersection between the 2 curves defines a unique blood flow rate, which is both CO and VR at the same time.

Pulmonary atresia with intact ventricular septum in the fetus

1992 ◽  
Vol 2 (4) ◽  
pp. 367-376 ◽  
Author(s):  
Lindsey D. Allan ◽  
Andrew Cook
Keyword(s):  
Right Ventricle ◽  
Poor Prognosis ◽  
Pulmonary Atresia ◽  
Ventricular Septum ◽  
Fetal Life ◽  
Intact Ventricular Septum ◽  
Cross Sectional ◽  
The One ◽  
The Right ◽  
Echocardiographic Findings

AbstractThe objective of this study was to review the echocardiographic findings and autopsy correlates of pulmonary atresia with an intact ventricular septum when diagnosed during fetal life. All cases with this lesion (nearly 60) seen in the Perinatal Cardiology unit of Guy's Hospital since 1983 are part of this study. More than half of the cases were detected within the last two years, and all bar three were referred because of suspicion of a cardiac malformation detected on routine obstetric scanning. The cases were divided into two distinct groups. On the one hand were those with dilatation of the chambers of the right heart. These had a uniformly poor prognosis. Severe regurgitation of the tricuspid valve was a characteristic feature. On the other hand were the cases with cavitary hypoplasia due to mural overgrowth. Direct measurements of pressure in one such case revealed suprasystemic values in the right ventricle. Although contemplated, fetal intervention proved impossible. Autopsy revealed cases with either valvar or infundibular atresia. In most cases diagnosed prior to 24 weeks of gestation, mothers opted for termination of pregnancy. All cases with dilatation of the right ventricle died. Of pregnancies which continued, only 30% of children are still alive, all but one being less than two years of age at present. The use of cross-sectional and Doppler echocardiography permits the accurate diagnosis of pulmonary atresia with an intact ventricular septum during fetal life. Autopsied cases showed strong correlation with the echocardiographic findings. The poor prognosis in most cases warrants consideration in the future of intervention during fetal life.

scholarly journals The role of focus marking in disjunctive questions: A QUD-based approach

2021 ◽  
Vol 30 ◽  
pp. 654
Author(s):  
Morwenna Hoeks
Keyword(s):  
The Other ◽  
Congruence Condition ◽  
Contrastive Topic ◽  
Structural Differences ◽  
Alternative Questions ◽  
The Difference ◽  
The One ◽  
The Right ◽  
Focus Marking

Disjunctive questions are ambiguous: they can either be interpreted as polar questions (PolQs), as open disjunctive questions (OpenQs), or as closed alternative questions (ClosedQ). The goal of this paper is to show that the difference in interpretation between these questions can be derived via effects of focus marking directly. In doing so, the proposal brings out the striking parallel between the prosody of questions with foci/contrastive topics on the one hand and that of alternative questions on the other. Unlike previous approaches, this proposal does not rely on structural differences between AltQs and PolQs derived via ellipsis or syntactic movement. To show how this works out, an account of focus and contrastive topic marking in questions is put forward in which f-marking in questions determines what constitutes a possible answer by signaling what the speaker's QUD is like. By imposing a congruence condition between f-marked questions and their answers that requires answers to resolve the question itself as well as its signaled QUD, we predict the right answerhood conditions for disjunctive questions.

La dichiarazione Dignitatis Humanae: Rottura o Riforma e Rinnovamento nella continuità dell’unico soggetto Chiesa?

2019 ◽  
Vol 48 (2) ◽  
pp. 377-395
Author(s):  
Agostino Marchetto
Keyword(s):  
Religious Freedom ◽  
Human Person ◽  
Essential Elements ◽  
Historical Background ◽  
The Public ◽  
Vatican Council ◽  
The Difference ◽  
The One ◽  
The Right ◽  
The Church

The contribution starts with a status quaestionis which concerns its title about the hermeneutics of Vatican ii, well based in historical background. The roots are grounded in the difference between “event” and “occurrence” – in italian “evento” e “avvenimento”. This is linked with the change in the perspective of historiography realized in the first part of the last century. The vision of continuity (see “Annales”) was put aside, introducing the one of “events”, which are linked with “ruptures” and not continuity in the course of history. With this frame we can understand that in the one of the Church there must be consideration for the hermeneutics expressed finally in the formula of the title closed by a question mark, that is: D.H.: rupture or reform and renewal in the continuity of the unique subject the Church? The answer is: no rupture in discontinuity but reform and renewal. The initial input of the contribution are the speeches of Pope Francis in the U.S.A. and U.N., an answer to the actual Sitz im Leben as far as religious freedom in nowadays society, 50 years after D.H., in a moment in which more attention is given to the texts of Vatican ii, concretely avoiding to consider “the Council of the Press” (Pope Benedict) instead of the one “of the conciliar Fathers” (= participants). The procedure of the author is certainly inspired by the volume Vatican ii. La liberté religieuse, ed. by J. Hamer and Y. Congar. The first point of attention therefore in the analysis is “homogeneous evolution of the pontifical doctrine on the matter”. It is a fundamental vision which allows even a dogmatic evolution, if it is homogeneous. In fact, the Declaration represented a development of the doctrine, a step forward in the progress of civilization, a progress in the catholic doctrine but in the line of no contradiction. And at this point the thoughts of the two fundamental pillars allowing this step forward are presented; they are J. Courtney Murray and P. Pavan. Very important is the Courtney’s statement in this regard, the following: “The doctrine of D.H. is in plenitude traditional, but it is also new, in the sense that tradition is always a developing and progressive tradition”. The author presents later on some essential elements of the right to religious freedom, with the most important and solemn affirmation in the text (N. 2): This Vatican Council declares that the human person has the right to religious freedom. It is truly an historical affirmation in the life of the Church and also for the human family. It follows the study of the relation between religious freedom and the public powers and the illustration of the education to exercise freedom under the light of the Revelation. In the final part of the essay the author analyses…some consequences of D.H. without forgetting a judgment about the actual situation of religious freedom in the world which is becoming always more serious and worrying. Here two citations of Archbishop Paul R. Gallagher, Secretary of the Relations with the States of the Papal Secretariat, are exemplary, that is: “Unfortunately we have to admit that for years the question of the violence against Christians was not taken in serious consideration. – He concluded: Even if we cannot speak of persecution in the old continent [Europe] nevertheless we must not underestimate the rather alarming phenomenon of the intolerance of religious character”.

Effect of partial hippocampal resection on stress mechanism in rats

1961 ◽  
Vol 201 (2) ◽  
pp. 337-340 ◽  
Author(s):  
Chul Kim ◽  
Chang Uk Kim
Keyword(s):  
Ascorbic Acid ◽  
Chronic Stress ◽  
Acid Content ◽  
Acute Stress ◽  
Ascorbic Acid Content ◽  
Inhibitory Influence ◽  
Acute And Chronic Stress ◽  
The Difference ◽  
The Right ◽  
And Control

Chronic (repeated skin incisions) as well as acute stress (left adrenalectomy) was applied to rats whose hippocampus had been damaged through the neocortex (hippocampus-damaged), to rats in which only the portion of the neocortex over the hippocampus had been damaged (neocortex-damaged), and to control rats. Both in the acute and chronic stress series, the left adrenal ascorbic acid content before stress was compared with that of the right adrenal gland following stress, and the difference served as a measure of reaction to the stress. Under acute stress, 72 rats showed a decrease in adrenal ascorbic acid content more pronounced in hippocampus-damaged rats and control animals than in the neocortex-damaged animals. Under chronic stress, increase in adrenal ascorbic acid content in 68 rats was least pronounced in hippocampus-damaged rats, most marked in neocortex-damaged animals, while the value was intermediate in control rats. The inference from these data is that the hippocampus exerts a sustained inhibitory influence upon the pituitary-adrenocortical mechanism.

scholarly journals The Right Way Through the Region of Sin: Islam, Bioethics and New Reproductive Technologies

2010 ◽  
Vol 5 (3) ◽  
pp. 133-163
Author(s):  
Marko Pišev
Keyword(s):  
Reproductive Technologies ◽  
The Other ◽  
Religious Thought ◽  
Islamic Ethics ◽  
House Of Lords ◽  
Scientific Approach ◽  
The Difference ◽  
Religious Dogma ◽  
The One ◽  
The Right

In the 1980s numerous debates were held in the House of Lords on the scientific research of embryos, with certain participants attempting to point out the difference between two styles of thought, namely, religious and scientific thought. Yet was the conflict in the House of Lords between two styles of thinking, or rather between the proponents of the scientific approach, on the one hand, and the proponents of religious thought, on the other, for intellectual and moral domination in society? Clearly, these debates hinted at something beyond and something more complex than a mere concern about embryos. What was actually being problematized? Or, to put it differently, to what extent does the use of bioreproductive technologies call into question the notions and issues of ethics, procreation and kinship, regardless of the religious dogma that considers the possibilities of their application? This paper will be confined to an analysis of Islamic dogma and any correspondences between this dogma and certain aspects of the new reproductive technologies. Still, in order to be able to discuss the relation between the new reproductive technologies and Islamic ethics, it is necessary to devote the greater part of this paper to an interpretation of how man is perceived in the context of the Koran.

scholarly journals UJI BEDA PELANGGARAN TRAFFIC LIGHT BERDASARKAN LOKASI PELANGGARANNYA

2017 ◽  
Vol 8 (2) ◽  
pp. 65
Author(s):  
Ridayati Ridayati
Keyword(s):  
Traffic Light ◽  
Traffic Regulation ◽  
Significant Difference ◽  
Traffic Violations ◽  
Traffic Violation ◽  
The Difference ◽  
Mind Set ◽  
The One ◽  
The Right

The increasing of the vehicles flow on Yogya-Solo street causing congestion at some points in the Klaten district. The main cause of the congestion is the number of traffic violations which lead to the accidents. Bendogantungan, south Klaten, is one of the most congested point in this district. This study is aimed to determine the causes and the effects of traffic light violations and to examine the difference o f traffic light violations based on the point of violations in the intersection of bendogantungan, Yogya-Solo street. The results show that the practical mind-set of Klaten community in driving has created an instant community. Many people of that community have not realized yet on the importance of traffic regulation, this causes the number of accident. The result of analysis using SPSS 15 shows that there is a significant difference between the one way traffic violation at Empu Sedah street and eastward of Yogya-Solo street. The difference also appears between the one way traffic violations at Empu Sedah street and the westward of Yogya-Solo street. It also happens between the right turn of Ki Ageng Pandanaran street and the westward of Yogya-Solo street.

scholarly journals THE LAW AS VALUE

2019 ◽  
Vol 3 (88) ◽  
pp. 208
Author(s):  
Aleksandrs Baikovs
Keyword(s):  
Legal Aspect ◽  
Semantic Content ◽  
Research Literature ◽  
Apparent Lack ◽  
A Value ◽  
The Subject ◽  
The Difference ◽  
The One ◽  
The Right ◽  
Fundamental Values

The paper deals with the category of “values”, the right as a value, and fundamental values of law; including freedom, justice, and equality are analyzed.The relevance of the research is determined not only by the apparent lack of exploration of the problem but also by the fact that the value of right and legal values determine direction and meaning, as well as the content of the rules of law, which is their normative expression, and, ultimately, appearing as a kind of basis for the legal culture, the source of the legal consciousness’s formation and establishing a legal order, ensuring the efficiency of legal regulations due to the using the embodiment in reality of freedom, justice, equality.Legal norms themselves acquire the importance of values and become the subject of evaluation. Among values themselves, which act as an ideal justification of the rules of law, the rules of law themselves and assessments, on the one hand, there are not only close ties but also mutual transitions. Therefore, both their interrelated explanations and differentiation are necessary.In this regard, the role and importance of rights and of the abovestated legal values, including the historically-legal aspect, their historical conditionality are disclosed, the semantic content and the importance in the establishment of the legitimacy regime are analyzed, the points of view expressed in the  research literature on the nature of legal values, signs, hierarchy,  the role in social and normative regulation are considered, the difference between value and the object of value or good is emphasized.

Mastoid Pneumatization in Otosclerosis

1989 ◽  
Vol 98 (6) ◽  
pp. 451-454 ◽  
Author(s):  
Jacob Sadé ◽  
Susan Kremer ◽  
Anat Shatz ◽  
Irena Levit
Keyword(s):  
Hereditary Disease ◽  
The Other ◽  
Mastoid Pneumatization ◽  
X Ray ◽  
Healthy Control ◽  
The Difference ◽  
Ray Projection ◽  
The One ◽  
The Right

The extent of mastoid pneumatization in 150 otosclerotic ears was compared with that of 150 healthy control ears. The size of mastoid pneumatization was measured by use of the Schüller lateral x-ray projection with the help of computed planimetry. The measurements showed the average pneumatized area in otosclerotic ears to be 17.4 ± 5 cm2, in contrast to 12.9 ± 4 cm2 for the healthy control ears. The difference between the two groups was highly significant (p<.0001). While both groups showed a bell-shaped distribution of the measured pneumatized area, the curve of the otosclerotic ears was shifted significantly to the right. Our findings indicate a link between otosclerosis on the one hand and highly pneumatized mastoids on the other. This link between a hereditary disease and a specific type of pneumatization points to the likelihood that heredity also plays some role in determining the final type of pneumatization.

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