Listeria monocytogenes-reactive T lymphocyte clones with cytolytic activity against infected target cells.
1986 ◽
Vol 164
(1)
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pp. 363-368
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Keyword(s):
T Cells
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Lyt-2+ T cell clones were established from Listeria monocytogenes-infected mice. The clones secreted IFN-gamma after stimulation with spleen cells from L. monocytogenes-infected mice plus IL-2. Spleen cells from normal mice were not stimulatory. Furthermore, cloned T cells lysed L. monocytogenes-infected macrophages. Cytolysis was antigen-specific and H-2K-restricted. These findings suggest a role for specific cytotoxic T cells in the immune response to intracellular bacteria.
1976 ◽
Vol 143
(2)
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pp. 437-443
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2003 ◽
Vol 77
(12)
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pp. 7139-7142
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Keyword(s):
Identification and Characterization of Murine Cytotoxic T Cells That Kill Mycobacterium tuberculosis
2000 ◽
Vol 68
(6)
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pp. 3269-3274
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