scholarly journals Moraxella catarrhalis,a Human Respiratory Tract Pathogen

2009 ◽  
Vol 49 (1) ◽  
pp. 124-131 ◽  
Author(s):  
Timothy F. Murphy ◽  
G. Iyer Parameswaran
Keyword(s):  
Respiratory Tract ◽  
Moraxella Catarrhalis ◽  
Human Respiratory Tract ◽  
Tract Pathogen

scholarly journals Genome Analysis of Moraxella catarrhalis Strain RH4, a Human Respiratory Tract Pathogen

2012 ◽  
Vol 194 (24) ◽  
pp. 7021-7021
Author(s):  
S. P. W. de Vries ◽  
S. A. F. T. van Hijum ◽  
W. Schueler ◽  
K. Riesbeck ◽  
J. P. Hays ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Genome Analysis ◽  
Moraxella Catarrhalis ◽  
Human Respiratory Tract ◽  
Tract Pathogen

scholarly journals ATP-Binding Cassette (ABC) Transporters of the Human Respiratory Tract Pathogen, Moraxella catarrhalis: Role in Virulence

PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0158689 ◽  
Author(s):  
Timothy F Murphy ◽  
Aimee L. Brauer ◽  
Antoinette Johnson ◽  
Charmaine Kirkham
Keyword(s):  
Respiratory Tract ◽  
Abc Transporters ◽  
Moraxella Catarrhalis ◽  
Atp Binding ◽  
Human Respiratory Tract ◽  
Tract Pathogen ◽  
Atp Binding Cassette

scholarly journals Prevalence of Moraxella catarrhalis in patients of lower respiratory tract infection with underlying risk factors

2017 ◽  
Vol 4 (2) ◽  
pp. 442
Author(s):  
Alex Aiswariya ◽  
Kundoly Velayudhan Suseela ◽  
Das Subi
Keyword(s):  
Risk Factors ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Moraxella Catarrhalis ◽  
Lower Respiratory Tract ◽  
Care Hospital ◽  
Tract Pathogen ◽  
Underlying Risk

Background: Moraxella catarrhalis is a Gram-negative diplococcus, commonly found as a normal flora in the human upper respiratory tract. Recently, M. catarrhalis has emerged as an important and common human respiratory tract pathogen. This study was aimed to determine the rate of isolation of M. Catarrhalis in patients attending a tertiary care hospital with lower respiratory tract infection (LRTI), antibiotic susceptibility pattern and predisposing factors responsible for their infection.Methods: A prospective study was carried out in 1001 lower respiratory specimens from patients (above 20 years’ age) with suspected LRTI.  The study investigated by microscopic examination, culture and antibiotic sensitivity test according to the standard guidelines. Assessment of clinical significance of M. Catarrhalis was ascertained on the basis of preformed criteria.Results: A total of 60 clinically significant M. Catarrhalis were isolated from the 930 culture positive samples. The isolates showed maximum sensitivity to second and third generation cephalosporins (95%), azithromycin (90%) followed by amoxicillin clavulanic acid (85%). Rate of isolation was more in males (70%) and elderly people above 60 years (63.33%) were found to be more affected. Patients (58.33%) with Chronic Obstructive Pulmonary Diseases (COPD) were found to be more prone to get infection by M. Catarrhalis.Conclusions: Moraxella catarrhalis should be considered as significant lower respiratory tract pathogen especially in elderly patients with underlying risk factors like COPD.

PRELP enhances host innate immunity against respiratory tract pathogen Moraxella catarrhalis

Immunobiology ◽  
2016 ◽  
Vol 221 (10) ◽  
pp. 1154
Author(s):  
Guanghui Liu ◽  
David Ermert ◽  
Martin E. Johansson ◽  
Kristian Riesbeck ◽  
Anna M. Blom
Keyword(s):  
Innate Immunity ◽  
Respiratory Tract ◽  
Moraxella Catarrhalis ◽  
Tract Pathogen ◽  
Host Innate Immunity

scholarly journals Distribution of Virulence Genes in Moraxella catarrhalis Isolated from Clinical Samples in the North of Iran

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Mina Eghbali ◽  
Majid Baserisalehi ◽  
Masood Ghane
Keyword(s):  
Respiratory Failure ◽  
Respiratory Tract ◽  
Otitis Media ◽  
Moraxella Catarrhalis ◽  
Virulence Genes ◽  
Clinical Samples ◽  
Control Group ◽  
P Value ◽  
Human Respiratory Tract ◽  
Cross Sectional

Background: Moraxella catarrhalis is an opportunistic bacterium that has pathogenicity in the human respiratory tract. The rates of colonization and infection of this bacterium are high in the respiratory tract of children and the elderly. Methods: In this descriptive cross-sectional study conducted from April 2016 to March 2018, 400 samples were collected from patients with pharyngitis (n = 92), sinusitis (n = 85), otitis media (n = 43), respiratory failure (n = 60), and healthy individuals as the control group (n = 120) in the Northern part of Iran. The isolates were identified by phenotyping methods. Finally, the virulence genes in the isolates were detected by polymerase chain reaction (PCR) technique. Results: Out of a total number of 400 samples, 32 samples (8%) were positive for M. catarrhalis. The frequency of this bacterium was found to be different in patients with pharyngitis as 5.44%, sinusitis as 8.24%, otitis media as 13.95%, respiratory failure as 15%, and in the control group as 4.16%. Since the P value from the Chi-square test was higher than 0.05, there was no relationship between the prevalence of M. catarrhalis and the type of the disease and control group. The PCR results showed that 100% of the isolates had mcaP, ompJ, and ompCD genes. However, the distribution of other virulence genes was varied. Conclusions: Overall, our findings verified the existence of M. catarrhalis in patients with respiratory diseases. Therefore, the rapid identification and successful treatment can play an important role in preventing their spread. In addition, the results verified the high prevalence of virulence genes in M. catarrhalis isolates from patients compared to controls. Regarding the results of this study and by comparing with similar studies, it can be concluded that the frequency of pathogenic isolates may be different even in regions that are not geographically different.

Moraxella Catarrhalis as a Respiratory Tract Pathogen during Umrah and Hajj Seasons

2018 ◽  
Vol 27 (3) ◽  
pp. 59-64
Author(s):  
Aiman M. Momenah
Keyword(s):  
Respiratory Tract ◽  
Moraxella Catarrhalis ◽  
Tract Pathogen

scholarly journals Draft Genome Sequence ofMoraxella catarrhalisType Strain CCUG 353T

2016 ◽  
Vol 4 (3) ◽  
Author(s):  
Hedvig E. Jakobsson ◽  
Francisco Salvà-Serra ◽  
Kaisa Thorell ◽  
Lucia Gonzales-Siles ◽  
Fredrik Boulund ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Genome Sequence ◽  
Moraxella Catarrhalis ◽  
Type Strain ◽  
Respiratory Tract Infections ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Human Respiratory Tract ◽  
Total Size ◽  
Tract Infections

Moraxella catarrhalisis a Gram-negative commensal and pathogenic bacterium found in the human respiratory tract. It is associated with otitis media and respiratory tract infections. Here, we report the draft genome sequence ofM. catarrhalistype strain CCUG 353T, composed of 18 contigs and a total size of 1.89 Mb.

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