Development of a novel drug targeting delivery system for cervical cancer therapy

2018 ◽  
Vol 30 (7) ◽  
pp. 075604 ◽  
Author(s):  
Li Xiao ◽  
Ni Ma ◽  
Huimin He ◽  
Jinmei Li ◽  
Sinan Cheng ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Therapy ◽  
Delivery System ◽  
Drug Targeting ◽  
Targeting Delivery ◽  
Novel Drug

scholarly journals 622. Oncolytic Adenoviruses Loaded With Active Drugs as a Novel Drug Delivery System for Cancer Therapy

2015 ◽  
Vol 23 ◽  
pp. S247
Author(s):  
Mariangela Garofalo ◽  
Barbara Iovine ◽  
Lukasz Kuryk ◽  
Cristian Capasso ◽  
Mari Hirvinen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oncolytic Adenoviruses ◽  
Novel Drug Delivery System ◽  
Novel Drug

Bionanotherapeutics: niclosamide encapsulated albumin nanoparticles as a novel drug delivery system for cancer therapy

RSC Advances ◽  
2015 ◽  
Vol 5 (16) ◽  
pp. 12078-12086 ◽  
Author(s):  
Bharat Bhushan ◽  
Poornima Dubey ◽  
S. Uday Kumar ◽  
Abhay Sachdev ◽  
Ishita Matai ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Albumin Nanoparticles ◽  
Scope Of Application ◽  
Novel Drug Delivery System ◽  
Novel Drug

In this work niclosamide was encapsulated into albumin nanoparticles through a desolvation method to improve its scope of application in cancer therapy.

scholarly journals A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis

RSC Advances ◽  
2015 ◽  
Vol 5 (116) ◽  
pp. 95545-95550 ◽  
Author(s):  
N. Micale ◽  
A. Piperno ◽  
N. Mahfoudh ◽  
U. Schurigt ◽  
M. Schultheis ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Delivery System ◽  
Drug Targeting ◽  
Biological Recognition ◽  
Targeting Delivery

A new HA–Pent bioconjugate was synthetized and proposed as drug targeting delivery system for the treatment of leishmaniasis, exploiting the specific biological recognition of HA by the macrophage.

scholarly journals Mucoadhesive Microspheres: A Targeted Drug Delivery System

2021 ◽  
Vol 11 (2-S) ◽  
pp. 150-155
Author(s):  
Hans Raj ◽  
Ankita Sharma ◽  
Shagun Sharma ◽  
Kapil Kumar Verma ◽  
Amit Chaudhary
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Targeted Drug Delivery ◽  
Drug Targeting ◽  
Local Effects ◽  
Targeted Drug ◽  
Novel Drug ◽  
Targeted Drug Delivery System ◽  
The Ideal

Carrier technology is a novel and groundbreaking drug delivery system. Microspheres transmit the drug by affixing it to carrier particle-like Microspheres, Nanoparticles and Liposomes due to their smaller size and other useful properties. Mucoadhesive Microspheres are an integral component of this multi-particle drug delivery system and play an important function in the delivery of a novel drug. This drug delivery improves the therapeutic effectiveness of the drug. Mucoadhesive microspheres have a longer duration of residence at the absorption site, which leads to the accuracy of the drug targeting at the absorption site and improves the therapeutic efficacy of the drug. Mucoadhesive microspheres are formed by either systemic or local effects in gastrointestinal, oral, vaginal, nasal, rectal, ocular delivery. This is the ideal targeting device which could be done in a variety of ways. Keywords: Microspheres, Bioadhesion, Polymer, Bioavailability

Cardiological Biopharmaceuticals in the Conception of Drug Targeting Delivery: Practical Results and Research Perspectives

Acta Naturae ◽  
2012 ◽  
Vol 4 (3) ◽  
pp. 72-81 ◽  
Author(s):  
A. V. Maksimenko
Keyword(s):  
Cell Adhesion Molecules ◽  
Drug Targeting ◽  
Interventional Procedures ◽  
Target Localization ◽  
Clinical Use ◽  
Protein Conjugates ◽  
Research Perspectives ◽  
Significant Interest ◽  
Targeting Delivery ◽  
Molecular Sizes

The results of the clinical use of thrombolytic and antithrombotic preparations developed on the basis of protein conjugates obtained within the framework of the conception of drug targeting delivery in the organism are considered. A decrease has been noted in the number of biomedical projects focused on these derivatives as a result of various factors: the significant depletion of financial and organizational funds, the saturation of the pharmaceutical market with preparations of this kind, and the appearance of original means for interventional procedures. Factors that actively facilitate the conspicuous potentiation of the efficacy of bioconjugates were revealed: the biomedical testing of protein domains and their selected combinations, the optimization of molecular sizes for the bioconjugates obtained, the density of target localization, the application of cell adhesion molecules as targets, and the application of connected enzyme activities. Enzyme antioxidants and the opportunity for further elaboration of the drug delivery conception via the elucidation and formation of therapeutic targets for effective drug reactions by means of pharmacological pre- and postconditioning of myocardium arouse significant interest.

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