The study of thermal processes of the skin of the object of the whole-body cryotherapy (WBC) using numerical analysis

Background: The activity of antioxidant enzymes and sirtuins (Sirt) decreases along with age, which is counteracted by aerobic training. Sirtuins increase antioxidant defence. Whole-body cryotherapy (WBC) increases total antioxidant capacity (TAC) in young men. The aim of our study was to assess the impact of 24 WBC treatments on the blood concentration of selected sirtuins and the level of antioxidant defence as well as oxidative stress index of training and non-training men depending on age. Methods: The study involved 40 males. In each group, there were 10 non-training older and young men (60 NTR and 20 NTR), and 10 older and young long-distance runners (60 TR, 20 TR). During an 8-week period, participants underwent 24 WBC treatments (3 min −130 °C), which were performed three times a week (Monday, Wednesday, Friday). The concentrations of Sirt1, Sirt3, TAC, total oxidative status and the activity of superoxide dismutase (SOD), catalase and glutathione peroxidase (GPx) in the blood were determined before 1 WBC and after 1 WBC, 12 WBC and 24 WBC. Results: After 1 WBC, the activity of GPx and the concentration of Sirt1 and TAC in 60 TR and TAC in 60 NTR increased. After 12 WBC, the level of Sirt1 in 20 NTR and SOD in 20 TR increased. After 24 WBC, the level of Sirt1 increased in 60 TR and in 20 NTR, Sirt3 in 60 TR and SOD in 20 TR. Conclusions: Cryogenic temperatures increase blood levels of Sirt1 and Sirt3 and systemic antioxidant defence in men, but the effect is dependent on age, level of performed physical activity and the number of applied treatments.

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The improvement of cognitive deficits after whole-body cryotherapy – A randomised controlled trial

Experimental Gerontology ◽

10.1016/j.exger.2021.111237 ◽

2021 ◽

Vol 146 ◽

pp. 111237

Author(s):

Joanna Rymaszewska ◽

Katarzyna M. Lion ◽

Bartłomiej Stańczykiewicz ◽

Julia E. Rymaszewska ◽

Elżbieta Trypka ◽

...

Keyword(s):

Randomised Controlled Trial ◽

Cognitive Deficits ◽

Controlled Trial ◽

Whole Body ◽

Randomised Controlled ◽

Whole Body Cryotherapy

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Effect of Whole-Body Cryotherapy on Morphological, Rheological and Biochemical Indices of Blood in People with Multiple Sclerosis

Journal of Clinical Medicine ◽

10.3390/jcm10132833 ◽

2021 ◽

Vol 10 (13) ◽

pp. 2833

Author(s):

Bartłomiej Ptaszek ◽

Aneta Teległów ◽

Justyna Adamiak ◽

Jacek Głodzik ◽

Szymon Podsiadło ◽

...

Keyword(s):

Multiple Sclerosis ◽

Neurological Diseases ◽

Venous Blood ◽

Whole Body ◽

Controlled Study ◽

Control Group ◽

Blood Indices ◽

Rheological Indices ◽

Whole Body Cryotherapy ◽

The Impact

The aim of this study was to examine and assess the impact of a series of 20 whole-body cryotherapy (WBC) treatments on the biochemical and rheological indices of blood in people with multiple sclerosis. In this prospective controlled study, the experimental group consisted of 15 women aged 34–55 (mean age, 41.53 ± 6.98 years) with diagnosed multiple sclerosis who underwent a series of whole-body cryotherapy treatments. The first control group consisted of 20 women with diagnosed multiple sclerosis. This group had no intervention in the form of whole-body cryotherapy. The second control group consisted of 15 women aged 30–49 years (mean age, 38.47 ± 6.0 years) without neurological diseases and other chronic diseases who also underwent the whole-body cryotherapy treatment. For the analysis of the blood indices, venous blood was taken twice (first, on the day of initiation of whole-body cryotherapy treatments and, second, after a series of 20 cryotherapy treatments). The blood counts were determined using an ABX MICROS 60 hematological analyzer (USA). The LORCA analyzer (Laser–Optical Rotational Cell Analyzer, RR Mechatronics, the Netherlands) was used to study the aggregation and deformability of erythrocytes. The total protein serum measurement was performed using a Cobas 6000 analyzer, Roche and a Proteinogram-Minicap Sebia analyzer. Fibrinogen determinations were made using a Bio-Ksel, Chrom-7 camera. Statistically significant differences and changes after WBC in the levels of red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), elongation index, total extend of aggregation (AMP), and proteins (including fibrinogen) were observed. However, there was no significant effect of a series of 20 WBC treatments on changes in blood counts, rheology, and biochemistry in women with multiple sclerosis. Our results show that the use of WBC has a positive effect on the rheological properties of the blood of healthy women.

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The effects of whole-body cryotherapy on oxidative stress in multiple sclerosis patients

Journal of Thermal Biology ◽

10.1016/j.jtherbio.2010.08.006 ◽

2010 ◽

Vol 35 (8) ◽

pp. 406-410 ◽

Cited By ~ 24

Author(s):

Elżbieta Miller ◽

MaŁgorzata Mrowicka ◽

Katarzyna Malinowska ◽

Jerzy Mrowicki ◽

Joanna Saluk-Juszczak ◽

...

Keyword(s):

Oxidative Stress ◽

Multiple Sclerosis ◽

Whole Body ◽

Multiple Sclerosis Patients ◽

Whole Body Cryotherapy

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IMPACT OF WHOLE BODY CRYOTHERAPY ON THE BLOOD PLASMA VISCOSITY AND FIBRINOGEN CONCENTRATION IN WOMEN WITH RHEUMATOID ARTHRITIS

Journal of Kinesiology and Exercise Sciences ◽

10.5604/01.3001.0012.1432 ◽

2017 ◽

Vol 27 (79) ◽

pp. 85-89

Author(s):

Bartłomiej Ptaszek ◽

Jakub Marchewka ◽

Aneta Teległów

Keyword(s):

Rheumatoid Arthritis ◽

Blood Plasma ◽

Treatment Time ◽

Venous Blood ◽

Body Height ◽

Plasma Viscosity ◽

Whole Body ◽

Fibrinogen Concentration ◽

Plasma Parameters ◽

Whole Body Cryotherapy

Study aim: The aim of this study was to assess the effects of whole body cryotherapy on the plasma viscosity and fibrinogen in women with rheumatoid arthritis. Study group: The study groups consisted of 10 womens with rheumatoid arthritis, aged 57.2 ± 9.4, who underwent systemic cryotherapy treatments (3 min treatment time, -120°C chamber temperature, 10 treatment sessions, 5 times a week). Their average body height was 165.5 ± 4.6 cm, weight 68.5 ± 4.9 kg and BMI 24.8 ± 2.2 kg/m2. In order to analyse plasma parameters, venous blood samples were drawn from the participants of the study twice. The first study was held on the day of beginning treatments and the second test was conducted after a series of 10 treatments. Methodology: The viscosity of the blood plasma was determined in the viscometer (type D-52159 Roetgen, Myrenne Co., Germany). Determination of plasma fibrinogen was performed using the Bio-Ksel, Chrom – 7 camera. Results: Analysing the average values of plasma viscosity and fibrinogen in women with rheumatoid arthritis before and after whole body cryotherapy, no statistically significant differences were found. Conclusions: Regular usage of cryotherapy treatments (whole body cryotherapy) not affect the levels of fibrinogen and plasma viscosity in women with rheumatoid arthritis.

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AB0661 Impact of whole-body cryotherapy on transcriptome of peripheral blood cells in patients with fibromyalgia

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-eular.2983 ◽

2013 ◽

Vol 72 (Suppl 3) ◽

pp. A990.4-A991

Author(s):

S. Drynda ◽

O. Mika ◽

D. Koczan ◽

J. Kekow

Keyword(s):

Peripheral Blood ◽

Blood Cells ◽

Whole Body ◽

Peripheral Blood Cells ◽

Whole Body Cryotherapy

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Could whole-body cryotherapy (below âˆ’100Â°C) improve muscle recovery from muscle damage?

Frontiers in Physiology ◽

10.3389/fphys.2014.00247 ◽

2014 ◽

Vol 5 ◽

Cited By ~ 18

Author(s):

Joao B. Ferreira-Junior ◽

Martim Bottaro ◽

Jeremy P. Loenneke ◽

Amilton Vieira ◽

Carlos A. Vieira ◽

...

Keyword(s):

Muscle Damage ◽

Whole Body ◽

Muscle Recovery ◽

Whole Body Cryotherapy

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Effects of Whole-Body Cryotherapy in Comparison with Other Physical Modalities Used with Kinesitherapy in Rheumatoid Arthritis

BioMed Research International ◽

10.1155/2015/409174 ◽

2015 ◽

Vol 2015 ◽

pp. 1-7 ◽

Cited By ~ 15

Author(s):

Małgorzata Gizińska ◽

Radosław Rutkowski ◽

Wojciech Romanowski ◽

Jacek Lewandowski ◽

Anna Straburzyńska-Lupa

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis ◽

Rehabilitation Program ◽

Whole Body ◽

Study Group ◽

Clinical Parameters ◽

Positive Effects ◽

Whole Body Cryotherapy ◽

Necrosis Factor ◽

Physical Modalities

Whole-body cryotherapy (WBC) has been frequently used to supplement the rehabilitation of patients with rheumatoid arthritis (RA). The aim of this study was to compare the effect of WBC and traditional rehabilitation (TR) on clinical parameters and systemic levels of IL-6, TNF-αin patients with RA. The study group comprised 25 patients who were subjected to WBC (−110°C) and 19 patients who underwent a traditional rehabilitation program. Some clinical variables and levels of interleukin-6 (IL-6) and tumor necrosis factor-α(TNF-α) were used to assess the outcomes. After therapy both groups exhibited similar improvement in pain, disease activity, fatigue, time of walking, and the number of steps over a distance of 50 m. Only significantly better results were observed in HAQ in TR group (p< 0.05). However, similar significant reduction in IL-6 and TNF-αlevel was observed. The results showed positive effects of a 2-week rehabilitation program for patients with RA regardless of the kind of the applied physical procedure.

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