A simple cantilever system for measurement of flow rates in paper microfluidic devices

2019 ◽  
Vol 1 (2) ◽  
pp. 025019
Author(s):  
Omar Mohd ◽  
Mohamad S Sotoudegan ◽  
Frances S Ligler ◽  
Glenn M Walker
Keyword(s):  
Microfluidic Devices ◽  
Flow Rates ◽  
Paper Microfluidic

A Multifunctional Microfluidic Device Based on Bifurcation Geometry

2010 ◽  
Author(s):  
Ahmed Fadl ◽  
Stefanie Demming ◽  
Zongqin Zhang ◽  
Bjo¨rn Hoxhold ◽  
Stephanus Bu¨ttgenbach ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Microfluidic Devices ◽  
Optical Lithography ◽  
Working Fluid ◽  
The Novel ◽  
Flow Rates ◽  
Single Function ◽  
Fluidic Device ◽  
Bifurcation Structures ◽  
Novel Design

Developing multifunctional devices are essential to realize more efficient Microsystems. With miniaturization processes taking place in many different applications, the rooms for single function microfluidic devices are limited. In this study, we introduce a multifunctional micro fluidic device based on bifurcation geometry which is capable of performing pumping and mixing at the same time. Optical lithography is used to fabricate the designed microfluidic device. The microfluidic device is tested at low actuator frequencies, and ethanol is employed as a working fluid. The operational principles are based on rectifying the oscillatory flows by using bifurcation structures for flow rectification. The results prove the feasibility of the novel design, and results are presented in terms of flow rates and maximum back pressures.

scholarly journals Using printer ink color to control the behavior of paper microfluidics

Lab on a Chip ◽  
2019 ◽  
Vol 19 (11) ◽  
pp. 2000-2008 ◽  
Author(s):  
Joshua Potter ◽  
Philip Brisk ◽  
William H. Grover
Keyword(s):  
Microfluidic Devices ◽  
Paper Microfluidics ◽  
Paper Microfluidic

Different colors of wax inks behave differently in paper microfluidic devices, enabling the development of new color-based paper microfluidic components.

A Fast Method for Determining the Flow Conductance of Gas Microfluidic Devices

2010 ◽  
Vol 132 (12) ◽  
Author(s):  
Matteo Martinelli ◽  
Vladimir Viktorov
Keyword(s):  
Pressure Ratio ◽  
Time Derivative ◽  
Microfluidic Devices ◽  
Low Flow ◽  
Thermal Bath ◽  
Fast Method ◽  
Flow Rates ◽  
Pressure Drops ◽  
Upstream Pressure ◽  
Computerized Data Processing

This paper presents a fast method for determining the conductance of gas microfluidic devices with low flow rates and very small pressure drops starting from 30 Pa, corresponding to Re=0.3. This method is based on discharging a gas-pressurized chamber through the microfluidic device under test. The microfluidic device’s conductance can be estimated as a function of inlet pressure and the Reynolds number of the flow by recording the upstream pressure during the discharging process and calculating the time derivative of the gas pressure. The pressurized chamber is considered as an isothermal chamber. Experimental results show that a sufficiently accurate isothermal discharging process up to an upstream-to-downstream pressure ratio of 0.8 can be achieved by immersing the chamber in a thermal bath. The method presented here is very fast, requiring only a few seconds for the acquisition procedure and computerized data processing.

scholarly journals Citizen-Led Sampling to Monitor Phosphate Levels in Freshwater Environments Using a Simple Paper Microfluidic Device

2021 ◽  
Author(s):  
Samantha Richardson ◽  
Alexander Iles ◽  
Jeanette M. Rotchell ◽  
Tim Charlson ◽  
Annabel Hanson ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Mobile Technology ◽  
High Frequency ◽  
Microfluidic Devices ◽  
Cost Effective ◽  
Smartphone App ◽  
Test Device ◽  
Monitoring Campaign ◽  
Paper Microfluidic ◽  
Freshwater Environments

We demonstrate how a combination of paper microfluidic devices and handheld mobile technology can be used by citizen scientists to carry out a sustained water monitoring campaign. We have developed a paper-based analysis device and a 3 minute sampling workflow that requires no more than a container, a test device and a smartphone app. The contaminant measured in these pilots are phosphates, detectable down to 3 mg L<sup>-1</sup>. Together these allow volunteers to successfully carry out cost-effective, high frequency, phosphate monitoring over an extended geographies and periods.

scholarly journals Elasto-Magnetic Pumps Integrated within Microfluidic Devices

2021 ◽  
Vol 4 (1) ◽  
pp. 48
Author(s):  
Jacob L. Binsley ◽  
Elizabeth L. Martin ◽  
Thomas O. Myers ◽  
Stefano Pagliara ◽  
Feodor Y. Ogrin
Keyword(s):  
Magnetic System ◽  
Point Of Care ◽  
Microfluidic Channel ◽  
Lab On A Chip ◽  
Microfluidic Devices ◽  
Point Of Care Testing ◽  
Ongoing Research ◽  
Flow Rates ◽  
Pumping System ◽  
Oscillating Magnetic Field

Many lab-on-a-chip devices require a connection to an external pumping system in order to perform their function. While this is not problematic in typical laboratory environments, it is not always practical when applied to point-of-care testing, which is best utilized outside of the laboratory. Therefore, there has been a large amount of ongoing research into producing integrated microfluidic components capable of generating effective fluid flow from on-board the device. This research aims to introduce a system that can produce practical flow rates, and be easily fabricated and actuated using readily available techniques and materials. We show how an asymmetric elasto-magnetic system, inspired by Purcell’s three-link swimmer, can provide this solution through the generation of non-reciprocal motion in an enclosed environment. The device is fabricated monolithically within a microfluidic channel at the time of manufacture, and is actuated using a weak, oscillating magnetic field. The flow rate can be altered dynamically, and the direction of the resultant flow can be controlled by adjusting the frequency of the driving field. The device has been proven, experimentally and numerically, to operate effectively when applied to fluids with a range of viscosities. Such a device may be able to replace external pumping systems in portable applications.

scholarly journals Modelling-Guided Design of Paper Microfluidic Networks – A Case Study of Sequential Fluid Delivery

2020 ◽  
Author(s):  
Dharitri Rath ◽  
Bhushan Toley
Keyword(s):  
Mathematical Models ◽  
Low Cost ◽  
Microfluidic Devices ◽  
Computational Design ◽  
Engineering Problem ◽  
Richards Equation ◽  
Trial And Error ◽  
Microfluidic Networks ◽  
Paper Microfluidic ◽  
Flow Through

<p>Paper-based microfluidic devices are popular for their ability to automate multi-step assays for chemical or biological sensing at a low cost, but the design of paper microfluidic networks has largely relied on experimental trial and error. A few mathematical models of flow through paper microfluidic devices have been developed and have succeeded in explaining experimental flow behaviour. However, the reverse engineering problem of designing complex paper networks guided by appropriate mathematical models is largely unsolved. In this article, we demonstrate that a two-dimensional paper network (2DPN) designed to sequentially deliver three fluids to a test zone on the device can be computationally designed and experimentally implemented without trial and error. This was accomplished by three new developments in modelling flow through paper networks: i) coupling of the Richards equation of flow through porous media to the species transport equation, ii) modelling flow through assemblies of multiple paper materials (test membrane and wicking pad), and iii) incorporating limited-volume fluid sources. We demonstrate the application of this model in the optimal design of a paper-based signal-enhanced immunoassay for a malaria protein, P<i>f</i>HRP2. This work lays the foundation for the development of a computational design toolbox to aid in the design of paper microfluidic networks.</p>

Formation of Droplets in a T-Junction Microfluidic Device Using the Lattice Boltzmann Method

2009 ◽  
Author(s):  
Amit Gupta ◽  
S. M. Sohel Murshed ◽  
Ranganathan Kumar
Keyword(s):  
Lattice Boltzmann Method ◽  
Lattice Boltzmann ◽  
Microfluidic Devices ◽  
Continuous Phase ◽  
Main Channel ◽  
Flow Rates ◽  
Two Fluids ◽  
Junction Device ◽  
Boltzmann Method ◽  
Parameters Of Interest

In recent years, microfluidic devices that generate micron sized droplets/bubbles have found widespread applications in drug delivery, microanalysis, tumor destruction, as ultrasound agents and in chemical reactions at the micron level. In the current work, simulations results are being presented for a T-junction device for formation of micron-sized droplets using the lattice Boltzmann method. In this work, the key parameters of interest for estimating the frequency and volume of the generated droplets are the flow rates and viscosities of the two fluids, and the geometry of the flow channel. Simulations at low Capillary number indicate that droplets formed occupy the whole volume of the main channel and undergo a squeezing regime. At higher Ca, droplets of size smaller than the width of the channel are formed, and the frequency is dependent on the flow rates of the two liquids. The effect of the width of the dispersed and continuous phase channels is also investigated.

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