Short Communication: Contribution of the Immunovirological State and Traditional Cardiovascular Risk Factors to Low HDL-Cholesterol in HIV Patients

2010 ◽  
Vol 26 (11) ◽  
pp. 1167-1170 ◽  
Author(s):  
R. Palacios ◽  
S. Puerta ◽  
F. Orihuela ◽  
J. Olalla ◽  
J. Roldán ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Short Communication ◽  
Hdl Cholesterol ◽  
Hiv Patients ◽  
Low Hdl

scholarly journals Cardiovascular Risk Factors among First Year Medical Students

2017 ◽  
Vol 5 (2) ◽  
pp. 64-68
Author(s):  
Raj Krishna Dangol ◽  
Bibek Koju ◽  
Priya Lanjekar ◽  
Chandrashekhar Pulipati
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Medical Students ◽  
Cardiovascular Risk Factors ◽  
Hdl Cholesterol ◽  
First Year ◽  
Low Hdl ◽  
History Of ◽  
First Year Medical Students

Introduction: Detection of cardiovascular risk in young age is important to motivate them to modify life styles and seek health care early to lower the chances of acquiring cardiovascular disease in later age. This study was done to assess cardiovascular risk factors among first year medical students. Methods: A cross-sectional study was conducted throughout September and October 2017 in which all first year medical students from a medical college were assessed for the presence of cardiovascular risk factors. Participants’ demography, family history of illness, anthropometric measurements, and blood reports of lipid profile and fasting glucose were acquired. Data were analyzed with Statistical Package for Social Sciences (SPSS-21). Result: There were 99 participants; 55 males and 44 females. One or more risk factors were present in 87 (87.9%) participants. Moreover, 67.7% (n = 67) participants had more than one risk factors. Low HDL-cholesterol was the most common (n = 55, 55.6%) risk factor followed by elevated triacylglycerol (n = 47, 47.5%) and family history of hypertension (n = 45, 45.5%). There was no significant difference in presence of various risk factors between genders. Conclusion: There was higher prevalence of cardiovascular risk factors among first year medical students. Majority of them had more than one risk factors. Low HDL-cholesterol was the most common risk factor. The risk factors were comparable in males and females.

scholarly journals Associations between low HDL, sex and cardiovascular risk markers are substantially different in sub-Saharan Africa and the UK: analysis of four population studies

2021 ◽  
Vol 6 (5) ◽  
pp. e005222
Author(s):  
Rosamund Greiner ◽  
Moffat Nyrienda ◽  
Lauren Rodgers ◽  
Gershim Asiki ◽  
Louis Banda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Geometric Mean ◽  
Hdl Cholesterol ◽  
Sub Saharan Africa ◽  
Low Hdl ◽  
Sub Saharan ◽  
The Uk ◽  
The Relationship

IntroductionLow high-density lipoprotein (HDL) is widely used as a marker of cardiovascular disease risk, although this relationship is not causal and is likely mediated through associations with other risk factors. Low HDL is extremely common in sub-Saharan African populations, and this has often been interpreted to indicate that these populations will have increased cardiovascular risk. We aimed to determine whether the association between HDL and other cardiovascular risk factors differed between populations in sub-Saharan Africa and the UK.MethodsWe compared data from adults living in Uganda and Malawi (n=26 216) and in the UK (n=8747). We examined unadjusted and adjusted levels of HDL and applied the WHO recommended cut-offs for prevalence estimates. We used spline and linear regression to assess the relationship between HDL and other cardiovascular risk factors.ResultsHDL was substantially lower in the African than in the European studies (geometric mean 0.9–1.2 mmol/L vs 1.3–1.8 mmol/L), with African prevalence of low HDL as high as 77%. Total cholesterol was also substantially lower (geometric mean 3.3–3.9 mmol/L vs 4.6–5.4 mmol/L). In comparison with European studies the relationship between HDL and adiposity (body mass index, waist to hip ratio) was greatly attenuated in African studies and the relationship with non-HDL cholesterol reversed: in African studies low HDL was associated with lower non-HDL cholesterol. The association between sex and HDL was also different; using the WHO sex-specific definitions, low HDL was substantially more common among women (69%–77%) than men (41%–59%) in Uganda/Malawi.ConclusionThe relationship between HDL and sex, adiposity and non-HDL cholesterol in sub-Saharan Africa is different from European populations. In sub-Saharan Africans low HDL is a marker of low overall cholesterol and sex differences are markedly attenuated. Therefore low HDL in isolation is unlikely to indicate raised cardiovascular risk and the WHO sex-based cut-offs are inappropriate.

Abstract P114: Metabolic Syndrome is Associated with Abnormal Ankle Brachial Index: Estimates From the National Health and Nutrition Examination Survey (1999-2004)

Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Sarah Singh ◽  
Courtney Pilkerton ◽  
Stephanie Frisbee
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Ankle Brachial Index ◽  
Hdl Cholesterol ◽  
P Value ◽  
Health And Nutrition ◽  
Low Hdl ◽  
The Relationship

Introduction: Metabolic syndrome (MetS) and low ankle-brachial index (ABI) share interrelated cardiovascular risk factors and are thus both strong indicators of an atherosclerotic process. However, few clinicians consider metabolic syndrome as a risk factor for abnormally low ABI and subsequent peripheral arterial disease. Therefore, it is necessary to highlight the relationship between abnormal ABI and MetS and the role of cardiovascular risk factors on this relationship. Hypothesis: We hypothesize that persons with MetS compared to those without, are more likely to experience abnormally low ABI even after accounting for additional cardiovascular risk factors not defined in the MetS. Methods: The eligible population consisted of 7,458 men and women aged 40 years and older, with and without cardiovascular disease (CVD) participating in The National Health and Nutrition Examination Survey from 1999-2004. Subjects were evaluated, according to the American Heart Association definitions, for abnormally low ABI < 1.0 (which included borderline low and low ABI) and metabolic syndrome with ≥ 3 of the following 5 components; central obesity, hypertriglyceridemia, low HDL cholesterol, hyperglycemia and hypertension. Ordinal logistic regression models were used to identify relationships between abnormal ABI and MetS, with adjustments for additional cardiovascular risk factors in multivariate models. Results: Participants with metabolic syndrome, as compared to those without, were 1.51 (95% CI, 1.01-2.26) times more likely to experience abnormally lower values of ABI after adjusting for gender, race, education, smoking and CRP. The relationship between abnormal ABI and MetS was modified by age (p value 0.01) but not by gender (p value 0.10) or race (p value 0.09). Additionally, odds of a lower ABI was highest for those with 4-5 components of MetS compared to those with 0-2 components (OR, 2.22; 95% CI, 1.44 to 3.43). Examining individual MetS components in fully adjusted models revealed that hypertriglyceridemia (OR, 1.69; 95% CI, 1.16 to 2.46) and low HDL cholesterol (OR, 1.81; 95% CI, 1.15 to 2.87) were associated with higher odds of abnormal ABI. Conclusions: In conclusion, the presence of MetS in adults with and without CVD was associated with abnormally low ABI, even after accounting for additional cardiovascular risk factors not defined by the MetS. This study suggests that timely clinician awareness of abnormally low ABI in persons with at least three MetS components, hypertriglyceridemia or low HDL cholesterol, may be useful in preventing the debilitating effects of peripheral artery disease.

scholarly journals Socioeconomic status and cardiovascular risk factors in young adults: a cross-sectional analysis of a Brazilian birth cohort

2020 ◽  
Vol 23 ◽  
Author(s):  
Fernando Alberto Costa Cardoso da Silva ◽  
Maylla Luanna Barbosa Martins Bragança ◽  
Heloisa Bettiol ◽  
Viviane Cunha Cardoso ◽  
Marco Antonio Barbieri ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Family Income ◽  
Sedentary Lifestyle ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Income ◽  
Low Hdl

ABSTRACT: Introduction: In high-income countries, persons of high socioeconomic status (SES) have a lower cardiovascular risk. However, in middle and low-income countries, the results are controversial. Objective: To evaluate the association between family income and cardiovascular risk factors in young adults. Methods: A total of 2,063 individuals of a birth cohort initiated in 1978/79 in the city of Ribeirão Preto, Brazil, were evaluated at age of 23/25 years. Cardiovascular risk factors (hypertension, sedentary lifestyle, smoking, low high-density lipoprotein (HDL)-cholesterol, high low-density lipoprotein (LDL)-cholesterol, high fibrinogen, insulin resistance, diabetes, abdominal and total obesity, and metabolic syndrome) were evaluated according to family income. Income was assessed in multiples of the minimum wage. Simple Poisson regression models were used to estimate the prevalence ratios (PR) with robust estimation of the variance. Results: High-income women showed lower prevalences of low HDL-cholesterol (PR = 0.47), total obesity (PR = 0.22), abdominal obesity (PR = 0.28), high blood pressure (PR = 0.28), insulin resistance (PR = 0.57), sedentary lifestyle (PR = 0.47), metabolic syndrome (PR = 0.24), and high caloric intake (PR = 0.71) (p < 0.05). High-income men showed lower prevalences of low HDL-cholesterol (PR = 0.73) and sedentarism (PR = 0.81) (p < 0.05). These results may be explained by the fact that high-income women pay more attention to healthy habits and those with the lowest family income are least likely to access health services resources and treatments. Conclusion: Women were in the final phase of the epidemiologic transition, whereas men were in the middle phase.

scholarly journals Burden of cardiovascular risk factors in stable HIV patients aged 50 years old and above

2020 ◽  
Vol 101 ◽  
pp. 284-285
Author(s):  
K.H. Tay ◽  
S. Chidambaram ◽  
L.H. Benedict Sim ◽  
K.C. Christopher Lee
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Hiv Patients

scholarly journals Diabetes and Hypertension among Patients Receiving Antiretroviral Treatment Since 1998 in Senegal: Prevalence and Associated Factors

ISRN AIDS ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Assane Diouf ◽  
Amandine Cournil ◽  
Khadidiatou Ba-Fall ◽  
Ndèye Fatou Ngom-Guèye ◽  
Sabrina Eymard-Duvernay ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Antiretroviral Treatment ◽  
Cross Sectional Study ◽  
Older Age ◽  
World Health ◽  
Resource Constrained ◽  
Hiv Patients ◽  
Cross Sectional

Cardiovascular risk factors in people on antiretroviral treatment (ART) are poorly documented in resource-constrained settings. A cross-sectional study was conducted in 2009 to assess prevalence of diabetes and hypertension in a sample of 242 HIV-infected patients who had initiated ART between 1998 and 2002 in Dakar, Senegal (ANRS 1215 observational cohort). World Health Organization (WHO) criteria were applied to diagnose diabetes and hypertension. Multiple logistic regressions were used to identify factors associated with diabetes and hypertension. Patients had a median age of 46 years and had received ART for a median duration of about 9 years. 14.5% had diabetes and 28.1% had hypertension. Long duration of ART (≥119 months), older age, higher body mass index (BMI), and higher levels of total cholesterol were associated with higher risks of diabetes. Older age, higher BMI at ART initiation, and higher levels of triglycerides were associated with higher risk of hypertension. This study shows that diabetes and hypertension were frequent in these Senegalese HIV patients on ART. It confirms the association between duration of ART and diabetes and highlights the need to implement programs for prevention of cardiovascular risk factors in HIV patients from resource-constrained settings.

scholarly journals A Mediterranean diet supplemented with dairy foods improves markers of cardiovascular risk: results from the MedDairy randomized controlled trial

2018 ◽  
Vol 108 (6) ◽  
pp. 1166-1182 ◽  
Author(s):  
Alexandra T Wade ◽  
Courtney R Davis ◽  
Kathryn A Dyer ◽  
Jonathan M Hodgson ◽  
Richard J Woodman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
At Risk ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Mediterranean Diet ◽  
Hdl Cholesterol ◽  
Mean Difference ◽  
Dairy Foods ◽  
Randomized Controlled

ABSTRACT Background The Mediterranean diet (MedDiet) offers benefits to cardiovascular health but may not meet Western recommendations for calcium and dairy intake, which could impede long-term adoption. Objective The current study aimed to determine the effect of a MedDiet supplemented with dairy foods on cardiovascular risk factors. Design A randomized, controlled, crossover design compared a MedDiet with 3–4 daily servings of dairy (MedDairy) and a low-fat (LF) control diet. Forty-one participants aged ≥45 y and at risk of cardiovascular disease (CVD) were randomly allocated to their first intervention, either the MedDairy or LF diet. Participants followed each intervention for 8 wk, and an 8-wk washout period separated interventions. The primary outcome was home-measured systolic blood pressure (SBP) assessed in the morning, afternoon, and evening. Secondary outcomes included clinic-measured blood pressure (morning), body composition, blood lipids, C-reactive protein (CRP), plasma glucose, serum insulin, and the Framingham Risk Score. Results Compared with the LF intervention, the MedDairy intervention resulted in a significantly lower morning SBP (mean difference: −1.6 mm Hg; 95% CI: −2.8, −0.4 mm Hg; P = 0.01), lower morning diastolic blood pressure (mean difference: −1.0; 95% CI: −1.7, −0.2 mm Hg; P = 0.01) and clinic SBP (mean difference: −3.5 mm Hg; 95% CI: −6.4, −0.7 mm Hg; P = 0.02), significantly higher HDL cholesterol (mean difference: 0.04 mmol/L; 95% CI: 0.01, 0.06 mmol/L; P < 0.01), lower triglycerides (mean difference: = −0.05 mmol/L; 95% CI: −0.08, −0.01 mmol/L; P < 0.01), and lower ratio of total to HDL cholesterol (mean difference: −0.4; 95% CI: −0.6, −0.2; P < 0.001). No effects were observed for other outcome measures. Conclusions Following a MedDiet with additional dairy foods led to significant changes in markers of cardiovascular risk over 8 wk. The MedDiet supplemented with dairy may be appropriate for an improvement in cardiovascular risk factors in a population at risk of CVD. This trial was registered at anzctr.org.au as ACTRN12616000309482.

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