Enterobacter cloacae Complex and CTX-M Extended-Spectrum β-Lactamases in Algeria

ABSTRACT The study evaluated the in vitro activity of ceftolozane-tazobactam (C/T) against 94 unique clinical isolates of Enterobacter cloacae complex (ECC). No difference was observed according to the ECC cluster. The in vitro activity greatly varied depending on the β-lactamase-producing profile: 100%, 67%, and 19% of wild-type, extended-spectrum β-lactamase (ESBL)-producing, and AmpC-overproducing strains, respectively, were susceptible to C/T. The use of C/T could be of interest for the treatment of some infections caused by ESBL-producing AmpC-nonoverexpressing ECC isolates.

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Epidemiology and pathogenicity of Enterobacter cloacae complex clinical isolates recovered from bone and joint infections

10.26226/morressier.56d5ba30d462b80296c955c7 ◽

2016 ◽

Author(s):

Vincent Cattoir

Keyword(s):

Enterobacter Cloacae ◽

Clinical Isolates ◽

Joint Infections ◽

Bone And Joint Infections ◽

Enterobacter Cloacae Complex

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P1346 Seventy Enterobacter cloacae bloodstream infections in central Taiwan during 2001 and 2003: evaluation of the roles of extended-spectrum β-lactamases and class 1 integron

International Journal of Antimicrobial Agents ◽

10.1016/s0924-8579(07)71186-x ◽

2007 ◽

Vol 29 ◽

pp. S373

Author(s):

C. Chen ◽

Y.-J. Chang ◽

C.-E. Liu ◽

C.-C. Huang

Keyword(s):

Bloodstream Infections ◽

Enterobacter Cloacae ◽

Class 1 Integron ◽

Extended Spectrum ◽

Class 1 ◽

Central Taiwan

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Draft Genome Sequences of Two Enterobacter cloacae subsp. cloacae Strains Isolated from Australian Hematology Patients with Bacteremia

Genome Announcements ◽

10.1128/genomea.00756-17 ◽

2017 ◽

Vol 5 (33) ◽

Cited By ~ 1

Author(s):

Lex E. X. Leong ◽

David Shaw ◽

Lito Papanicolas ◽

Diana Lagana ◽

Ivan Bastian ◽

...

Keyword(s):

Gut Microbiota ◽

Draft Genome ◽

Enterobacter Cloacae ◽

Opportunistic Pathogen ◽

Healthy Individuals ◽

Genome Sequences ◽

Content Type ◽

Extended Spectrum ◽

Genes Encoding

ABSTRACT Enterobacter cloacae is a common member of the gut microbiota in healthy individuals. However, it is also an opportunistic pathogen, capable of causing bacteremia. We report the draft genomes of two Enterobacter cloacae subspecies cloacae strains isolated from hematology patients with bacteremia. Both isolates carry genes encoding extended-spectrum β-lactamases.

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Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying blaIMI-Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.01542-17 ◽

2017 ◽

Vol 62 (1) ◽

Cited By ~ 6

Author(s):

Tse H. Koh ◽

Nurdyana Binte Abdul Rahman ◽

Jeanette W. P. Teo ◽

My-Van La ◽

Balamurugan Periaswamy ◽

...

Keyword(s):

Phylogenetic Analysis ◽

Whole Genome Sequencing ◽

Genome Sequencing ◽

Multilocus Sequence Typing ◽

Enterobacter Cloacae ◽

Mobile Elements ◽

Whole Genome ◽

Content Type ◽

Flanking Regions ◽

Enterobacter Cloacae Complex

ABSTRACT Whole-genome sequencing was performed on 16 isolates of the carbapenemase-producing Enterobacter cloacae complex to determine the flanking regions of bla IMI-type genes. Phylogenetic analysis of multilocus sequence typing (MLST) targets separated the isolates into 4 clusters. The bla IMI-type genes were all found on Xer-dependent integrative mobile elements (IMEX). The IMEX elements of 5 isolates were similar to those described in Canada, while the remainder were novel. Five isolates had IMEX elements lacking a resolvase and recombinase.

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