Annaeus Seneca, Lucius (1), Seneca 'the Elder', Roman author on declamation, c. 50 BCE–c. 40 CE

Author(s):  
Christian James Fordyce ◽  
M. Winterbottom
Keyword(s):  
Classics ◽  
2015 ◽  
Author(s):  
Stefan Feddern

Though Seneca the Elder (c. 50 bce–c. 40 ce) is a person almost unknown to us, his extant work, the Oratorum et rhetorum sententiae divisiones colores (excerpts of the two kinds of declamation, controversiae and suasoriae), is exceedingly rich in information about the early imperial declamation and about the literary culture of that period in general. While his historiographical work, the Historiae, has not survived (apart from a few fragments), his declamation excerpts document not only the declamation as such; they also offer us an insight into the whole process of declamation and the declamation schools. This insight is highly important for the history of declamation because it is the first one we possess, despite the fact that declamation itself is a phenomenon that originated in Greece and has a centuries-long tradition. It is important also for the history of rhetoric and for Roman education and culture in general because declamation formed an integral part of the curriculum of higher education. In its original state, Seneca the Elder’s declamatory work consisted of ten books of excerpts from controversiae (fictitious court cases), and there may have been perhaps at least a second book of excerpts from suasoriae (fictitious speeches of advice to historical or mythical personages). It is not known whether each book was introduced by a preface addressed to his sons, but it is likely that more prefaces existed than we have today. Unfortunately, only parts of the original work survive. In the process of transmission, probably in Late Antiquity, excerpts were drafted of Seneca the Elder’s declamatory work. These excerpts are shortened versions of the excerpts from the controversiae (not from the suasoriae), and they contain some prefaces that otherwise would have been lost. What we possess today is the sum of both of the traditions: the controversiae books 1, 2, 7, 9, and 10 and one book of suasoriae in the form that Seneca the Elder gave to them (the mentioned books of controversiae additionally exist in the form of the excerpts made in Late Antiquity). The controversiae books 3, 4, 5, 6, and 8 have survived only in the shortened form that they received in Late Antiquity. Finally, we possess the prefaces to books 1, 2, 3, 4, 7, 9, and 10 of the controversiae.


Author(s):  
Janet Fairweather
Keyword(s):  

1978 ◽  
Vol 39 (01) ◽  
pp. 193-200 ◽  
Author(s):  
Erwin F Workman ◽  
Roger L Lundblad

SummaryAn improved method for the preparation of bovine α-thrombin is described. The procedure involves the activation of partially purified prothrombin with tissue thromboplastin followed by chromatography on Sulfopropyl-Sephadex C-50. The purified enzyme is homogeneous on polyacrylamide discontinuous gel electrophoresis and has a specific activity toward fibrinogen of 2,200–2,700 N.I.H. U/mg. Its stability on storage in liquid media is dependent on both ionic strenght and temperature. Increasing ionic strength and decreasing temperature result in optimal stability. The denaturation of α-thrombin by guanidine hydrochloride was found to be a partially reversible process with the renatured species possessing properties similar to “aged” thrombin. In addition, the catalytic properties of a-thrombin covalently attached to agarose gel beads were also examined. The activity of the immobilized enzyme toward fibrinogen was affected to a much greater extent than was the hydrolysis of low molecular weight, synthetic substrates.


1981 ◽  
Vol 45 (02) ◽  
pp. 121-126 ◽  
Author(s):  
Utako Okamoto ◽  
Noboru Horie ◽  
Yoko Nagamatsu ◽  
Jun-Ichiro Yamamoto

SummaryMilk plasminogen-activator was partially purified from human transitional milk collected at about 10 days after delivery, by a five-step procedure involving chloroform treatment, ammonium sulfate precipitation, and column chromatography on Sephadex G-150, CM Sephadex C-50 and DEAE Sephadex A-50. This gave milk-activator with a maximum purification factor of about 2,400-fold with respect to the skimmed milk. The CM Sephadex-step preparation showed, on polyacrylamide gel electrophoresis, a single plasminogen-activator activity band located between the bands of albumin and prealbumin of human serum. This preparation exhibited no kinin forming activity. The activator hydrolyzed acetyl-glycyl-L-lysine methyl ester with similar order kinetic constants to urokinase, and was inhibited strongly by diisopropyl-fluorophosphate. The molecular weight of the activator as estimated by gel filtration was approximately 86,000, the isoelectric points as estimated by gel isoelectric focusing were pH 7.2, 6.9 and 6.6, and the activator activity was not quenched by antiurokinase globulin, indicating that the milk-activator is a different entity from urokinase.


2019 ◽  
Vol 30 (2) ◽  
pp. 54
Author(s):  
Leslie Tauany Schneider da Luz ◽  
Sandra Inês Adams Angnes Gomes ◽  
Marilei Casturina Mendes Sandri ◽  
Flávia De Mello ◽  
Juliana Aparecida Bolzan
Keyword(s):  

A síntese do ácido acetilsalicílico (AAS) é muito empregada em aulas experimentais de Química para explorar o ensino de reações nucleofílicas e o processo de purificação por recristalização. Considerando a diversidade de protocolos disponíveis na literatura, com divergências nas condições experimentais, este trabalho teve como objetivo otimizar as condições de tempo e temperatura da síntese do AAS e, concomitante, melhorar a verdura química do processo visando maior eficiência mássica e energética, de acordo com os princípios 1, 2 e 6 da Química Verde (QV). Para isso, propôs-se a síntese de AAS a temperaturas de 40 °C, 50 °C, 60 °C, 70 °C, 80 e 90 °C durante 10, 20, 30 e 40 minutos de reação. Os resultados apontam que o AAS obtido em 20 minutos a 80°C apresentou os melhores resultados: um bom rendimento, 77,70 ± 0,01 %, com ponto de fusão 133 °C-134 °C, com Eficiência de Massa 24 % e Fator E 3,10; as melhores métricas de energia, <em>Throughput</em> 0,101 g min<sup>-1</sup><em>, </em>Intensidade de Tempo  9,869 min g<sup>-1</sup>, Intensidade de Energia 0,073 Kw h g<sup>-1</sup> e o  menor consumo de energia, 0,1485 KWh, um ganho de eficiência energética de aproximadamente 200 %, contribuindo principalmente com melhorias no P6 da QV.


1987 ◽  
Vol 52 (5) ◽  
pp. 1356-1361
Author(s):  
S. Abdel Rahman ◽  
M. Elsafty ◽  
A. Hattaba

The conformation of elastin-like peptides Boc-Ala-Pro-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Ala-Pro-Gly-Val-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Gly-Val-Ala-Pro-Gly-Val-Gly-Val-APEGM were examined in solution using circular dichroism at 30 °C, 50 °C, and 70 °C and in solid state by IR at room temperature. The studies show that the β-turn is a significant conformational feature for peptides under investigation in solution at 30 °C and 50 °C, but at 70 °C the tetra, hexa, and decapeptides show the CD feature characteristic of the β-structure while the dodecapeptide spectra show the presence of β-turn which indicates the stability of the β-turn at this chain length. The IR spectra show that in the solid state at room temperature all investigated peptides assume essentially a β-turn except the tetrapeptide which present evidence of antiparallel β-structure. The β-turn contribution in the IR spectra increases with the increase of the chain length of the peptide.


Situated at the crossroads of rhetoric and fiction, the genre of declamatio offers its practitioners the freedom to experiment with new forms of discourse. This volume places the literariness of Roman declamation into the spotlight by showcasing its theoretical influences, stylistic devices, and generic conventions as related by Seneca the Elder, the author of the Controversiae and Suasoriae, which jointly make up the largest surviving collection of declamatory speeches from antiquity. In so doing, it draws attention to the complexity of these texts, and maps out, for the first time, the sociocultural context for their composition, delivery, and reception. The volume’s chapters have been authored by an international group of leading scholars in Latin literature and rhetoric, and explore not only the historical roles of individual declaimers but also the physical and linguistic techniques upon which they collectively drew. In addition, the ‘dark side of declamation’ is illuminated by contributions on the competitiveness of the arena and the manipulative potential of declamatory skill. In keeping with the volume’s overall treatment of declamation as a literary phenomenon, a section has also been dedicated to intertextuality. This comprehensive, innovative, and up-to-date treatment provides thought-provoking analyses of Roman declamation, and therefore constitutes an essential volume for both students and scholars in the fields of Latin literature, Republican Roman history, and rhetoric.


Catalysts ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1239
Author(s):  
Manuel Ramos ◽  
Félix Galindo-Hernández ◽  
Brenda Torres ◽  
José Manuel Domínguez-Esquivel ◽  
Martin Heilmaier

We report the thermal stability of spherically shaped cobalt-promoted molybdenum disulfide (Co/MoS2) nano-catalysts from in-situ heating under electron irradiation in the scanning transmission electron microscope (STEM) from room temperature to 550 °C ± 50 °C with aid of Fusion® holder (Protochip©, Inc.). The catalytic nanoparticles were synthesized via a hydrothermal method using sodium molybdate (Na2MoO4·2H2O) with thioacetamide (CH3CSNH2) and cobalt chloride (CoCl2) as promoter agent. The results indicate that the layered molybdenum disulfide structure with interplanar distance of ~0.62 nm remains stable even at temperatures of 550 °C, as observed in STEM mode. Subsequently, the samples were subjected to catalytic tests in a Robinson Mahoney Reactor using 30 g of Heavy Crude Oil (AGT-72) from the golden lane (Mexico’s east coast) at 50 atm using (ultrahigh purity) UHP hydrogen under 1000 rpm stirring at 350 °C for 8 h. It was found that there is no damage on the laminar stacking of Co/MoS2 with temperature, with interlayer spacing remaining at 0.62 nm; these sulfided catalytic materials led to aromatics rise of 22.65% and diminution of asphaltenes and resins by 15.87 and 3.53%, respectively.


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